Project

PRJNA207719: Tissue specific transcriptome profiling

Navigation
Downloads

Results for vsx2

Z-value: 1.45

Motif logo

logo of

Transcription factors associated with vsx2

Gene Symbol Gene ID Gene Info
vsx2
ENSDARG00000005574 visual system homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
vsx2dr11_v1_chr17_-_31659670_316596700.828.9e-02Click!

Activity profile of vsx2 motif

Sorted Z-values of vsx2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_28731379 2.47 ENSDART00000047378
cort
cortistatin
chr4_+_21129752 2.30 ENSDART00000169764
syt1a
synaptotagmin Ia
chr3_-_46817499 2.25 ENSDART00000013717
elavl3
ELAV like neuron-specific RNA binding protein 3
chr15_-_16098531 1.94 ENSDART00000080377
aldoca
aldolase C, fructose-bisphosphate, a
chr16_+_46111849 1.76 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr20_+_35382482 1.48 ENSDART00000135284
vsnl1a
visinin-like 1a
chr21_-_27185915 1.42 ENSDART00000135052
slc8a4a
solute carrier family 8 (sodium/calcium exchanger), member 4a
chr18_-_1185772 1.42 ENSDART00000143245
nptnb
neuroplastin b
chr5_-_16996482 1.40 ENSDART00000144501
galnt9
polypeptide N-acetylgalactosaminyltransferase 9
chr21_+_28958471 1.38 ENSDART00000144331
ENSDART00000005929
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr9_+_11532025 1.37 ENSDART00000109037
cdk5r2b
cyclin-dependent kinase 5, regulatory subunit 2b (p39)
chr21_+_32820175 1.24 ENSDART00000076903
adra2db
adrenergic, alpha-2D-, receptor b
chr22_-_20011476 1.15 ENSDART00000093312
ENSDART00000093310
celf5a
cugbp, Elav-like family member 5a
chr1_+_9290103 1.06 ENSDART00000055009
uncx4.1
Unc4.1 homeobox (C. elegans)
chr17_+_31185276 1.04 ENSDART00000062887
disp2
dispatched homolog 2 (Drosophila)
chr23_+_28582865 1.03 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr3_-_43356082 1.00 ENSDART00000171213
uncx
UNC homeobox
chr23_-_24195723 0.95 ENSDART00000145489
ano11
anoctamin 11
chr15_-_9272328 0.95 ENSDART00000172114
calm2a
calmodulin 2a (phosphorylase kinase, delta)
chr23_-_24195519 0.93 ENSDART00000112370
ENSDART00000180377
ano11
anoctamin 11
chr21_-_37790727 0.92 ENSDART00000162907
gabrb4
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr3_-_46811611 0.92 ENSDART00000134092
elavl3
ELAV like neuron-specific RNA binding protein 3
chr16_+_39159752 0.87 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr11_-_42554290 0.87 ENSDART00000130573
atp6ap1la
ATPase H+ transporting accessory protein 1 like a
chr11_+_18873619 0.73 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr11_-_37425407 0.71 ENSDART00000160911
erc2
ELKS/RAB6-interacting/CAST family member 2
chr5_-_64831207 0.71 ENSDART00000144816
lix1
limb and CNS expressed 1
chr14_+_25817628 0.71 ENSDART00000047680
glra1
glycine receptor, alpha 1
chr13_+_19322686 0.68 ENSDART00000058036
emx2
empty spiracles homeobox 2
chr6_-_12275836 0.68 ENSDART00000189980
pkp4
plakophilin 4
chr4_+_3980247 0.68 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr12_-_19862912 0.68 ENSDART00000145788
shisa9a
shisa family member 9a
chr12_-_35386910 0.67 ENSDART00000153453
camk2g1
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr18_+_7639401 0.66 ENSDART00000092416
rabl2
RAB, member of RAS oncogene family-like 2
chr4_-_17629444 0.65 ENSDART00000108814
nrip2
nuclear receptor interacting protein 2
chr24_-_23320223 0.64 ENSDART00000135846
zfhx4
zinc finger homeobox 4
chr21_+_6751405 0.61 ENSDART00000037265
ENSDART00000146371
olfm1b
olfactomedin 1b
chr15_-_22074315 0.59 ENSDART00000149830
drd2a
dopamine receptor D2a
chr10_+_42423318 0.57 ENSDART00000134282
npy8ar
neuropeptide Y receptor Y8a
chr11_+_38280454 0.56 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr18_-_2433011 0.56 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr18_+_14529005 0.51 ENSDART00000186379
kcng4a
potassium voltage-gated channel, subfamily G, member 4a
chr17_+_3379673 0.47 ENSDART00000176354
sntg2
syntrophin, gamma 2
chr24_-_21923930 0.47 ENSDART00000131944
tagln3b
transgelin 3b
chr7_+_36898850 0.43 ENSDART00000113342
tox3
TOX high mobility group box family member 3
chr5_+_5398966 0.43 ENSDART00000139553
mapkap1
mitogen-activated protein kinase associated protein 1
chr23_-_24483311 0.43 ENSDART00000185793
ENSDART00000109248
spen
spen family transcriptional repressor
chr14_+_23717165 0.43 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr22_-_21897203 0.42 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
gna11a
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr20_-_46362606 0.42 ENSDART00000153087
bmf2
BCL2 modifying factor 2
chr6_-_40713183 0.38 ENSDART00000157113
ENSDART00000154810
ENSDART00000153702
si:ch211-157b11.12
si:ch211-157b11.12
chr11_+_18873113 0.38 ENSDART00000103969
ENSDART00000103968
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr21_+_6751760 0.38 ENSDART00000135914
olfm1b
olfactomedin 1b
chr19_+_22062202 0.36 ENSDART00000100181
sall3b
spalt-like transcription factor 3b
chr2_-_16216568 0.36 ENSDART00000173758
arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr24_+_35881124 0.36 ENSDART00000143015
klhl14
kelch-like family member 14
chr13_-_44630111 0.35 ENSDART00000110092
mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr12_+_30367079 0.30 ENSDART00000190112
ccdc186
si:ch211-225b10.4
chr11_-_40418975 0.29 ENSDART00000086296
trim62
tripartite motif containing 62
chr20_+_29209615 0.29 ENSDART00000062350
katnbl1
katanin p80 subunit B-like 1
chr14_+_21820034 0.29 ENSDART00000122739
ctbp1
C-terminal binding protein 1
chr8_+_18588551 0.29 ENSDART00000177476
ENSDART00000063539
prrg1
proline rich Gla (G-carboxyglutamic acid) 1
chr14_+_23874062 0.27 ENSDART00000172149
sh3rf2
SH3 domain containing ring finger 2
chr5_-_48268049 0.24 ENSDART00000187454
mef2cb
myocyte enhancer factor 2cb
chr24_-_25004553 0.23 ENSDART00000080997
ENSDART00000136860
zdhhc20b
zinc finger, DHHC-type containing 20b
chr12_+_30367371 0.23 ENSDART00000153364
ccdc186
si:ch211-225b10.4
chr24_+_39518774 0.22 ENSDART00000132939
dcun1d3
defective in cullin neddylation 1 domain containing 3
chr18_-_24989580 0.18 ENSDART00000163449
chd2
chromodomain helicase DNA binding protein 2
chr23_+_23658474 0.17 ENSDART00000162838
agrn
agrin
chr1_+_10318089 0.16 ENSDART00000029774
pip4p1b
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr20_-_9436521 0.14 ENSDART00000133000
zgc:101840
zgc:101840
chr3_+_17537352 0.12 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr5_-_28109416 0.11 ENSDART00000042002
si:ch211-48m9.1
si:ch211-48m9.1
chr8_-_23776399 0.10 ENSDART00000114800
INAVA
si:ch211-163l21.4
chr20_-_20270191 0.09 ENSDART00000009356
ppp2r5ea
protein phosphatase 2, regulatory subunit B', epsilon isoform a
chr11_-_29768054 0.09 ENSDART00000079117
plekha3
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chr18_+_28106139 0.09 ENSDART00000089615
kiaa1549lb
KIAA1549-like b
chr24_-_35282568 0.08 ENSDART00000167406
ENSDART00000088609
sntg1
syntrophin, gamma 1
chr21_+_27370671 0.07 ENSDART00000009234
ENSDART00000142071
rbm14a
RNA binding motif protein 14a
chr7_+_22313533 0.07 ENSDART00000123457
TMEM102
si:dkey-11f12.2
chr20_+_29209767 0.07 ENSDART00000141252
katnbl1
katanin p80 subunit B-like 1
chr21_+_25231160 0.07 ENSDART00000063089
ENSDART00000139127
gng8
guanine nucleotide binding protein (G protein), gamma 8
chr13_-_36663358 0.04 ENSDART00000085319
sos2
son of sevenless homolog 2 (Drosophila)
chr5_+_38900249 0.03 ENSDART00000097856
fras1
Fraser extracellular matrix complex subunit 1
chr20_+_29209926 0.02 ENSDART00000152949
ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr6_-_8264751 0.00 ENSDART00000091628
ccdc151
coiled-coil domain containing 151

Network of associatons between targets according to the STRING database.

First level regulatory network of vsx2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.2 0.7 GO:0071361 cellular response to ethanol(GO:0071361)
0.2 0.9 GO:0060074 synapse maturation(GO:0060074)
0.2 1.9 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.1 1.4 GO:0042044 fluid transport(GO:0042044)
0.1 2.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.4 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 1.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.7 GO:0060118 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.1 0.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.4 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 0.7 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.1 0.2 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.0 1.4 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 1.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 1.0 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0042755 eating behavior(GO:0042755)
0.0 0.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 1.0 GO:0035195 gene silencing by miRNA(GO:0035195)
0.0 0.7 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.7 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.6 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.7 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.9 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.8 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.9 GO:0019722 calcium-mediated signaling(GO:0019722)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 1.4 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 1.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.9 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.7 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.5 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.8 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.6 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 1.4 GO:0042383 sarcolemma(GO:0042383)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 1.4 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 1.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 1.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.4 GO:0050699 WW domain binding(GO:0050699)
0.1 0.7 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.4 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 2.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.6 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.7 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.6 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 2.8 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.1 GO:1902387 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 0.5 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 2.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.4 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis