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PRJNA207719: Tissue specific transcriptome profiling

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Results for tfe3a+tfe3b

Z-value: 1.76

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Transcription factors associated with tfe3a+tfe3b

Gene Symbol Gene ID Gene Info
ENSDARG00000019457 transcription factor binding to IGHM enhancer 3b
ENSDARG00000098903 transcription factor binding to IGHM enhancer 3a
ENSDARG00000111231 transcription factor binding to IGHM enhancer 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tfe3bdr11_v1_chr11_+_25504215_25504215-0.553.3e-01Click!
tfe3adr11_v1_chr8_+_7778770_7778770-0.444.5e-01Click!

Activity profile of tfe3a+tfe3b motif

Sorted Z-values of tfe3a+tfe3b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_31665836 1.55 ENSDART00000135411
ENSDART00000143914
si:ch211-106h4.12
chr22_-_17677947 1.35 ENSDART00000139911
tight junction protein 3
chr5_-_29534748 1.32 ENSDART00000159587

chr20_-_17041025 1.24 ENSDART00000063764
si:dkey-5n18.1
chr16_-_45178430 1.22 ENSDART00000165186
si:dkey-33i11.9
chr3_-_16784280 1.19 ENSDART00000137108
ENSDART00000137276
si:dkey-30j10.5
chr9_-_56272465 1.07 ENSDART00000039235
lymphocyte cytosolic protein 1 (L-plastin)
chr9_-_33063083 1.05 ENSDART00000048550
si:ch211-125e6.5
chr21_-_22673758 1.00 ENSDART00000164910
grass carp reovirus (GCRV)-induced gene 2i
chr20_+_38257766 0.98 ENSDART00000147485
ENSDART00000149160
chemokine (C-C motif) ligand 38, duplicate 6
chr12_+_20336070 0.97 ENSDART00000066385
zgc:163057
chr23_-_31913231 0.97 ENSDART00000146852
ENSDART00000085054
mitochondrial fission regulator 2
chr14_+_52571134 0.93 ENSDART00000166708
ribosomal protein L26
chr20_-_39735952 0.92 ENSDART00000101049
ENSDART00000137485
ENSDART00000062402
tumor protein D52-like 1
chr7_-_19923249 0.92 ENSDART00000078694
zgc:110591
chr5_+_27404946 0.91 ENSDART00000121886
ENSDART00000005025
hematopoietic death receptor
chr7_-_67214972 0.90 ENSDART00000156861
switching B cell complex subunit SWAP70a
chr20_-_37813863 0.87 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr14_-_15171435 0.86 ENSDART00000159148
ENSDART00000166622
si:dkey-77g12.1
chr2_+_36007449 0.86 ENSDART00000161837
laminin, gamma 2
chr2_+_24507770 0.85 ENSDART00000154802
ENSDART00000052063
ribosomal protein S28
chr12_-_13155653 0.85 ENSDART00000152467
CX chemokine ligand 34c
chr18_-_1414760 0.83 ENSDART00000171881
peptidase D
chr10_+_41159241 0.82 ENSDART00000141657
annexin A4
chr7_-_8374950 0.82 ENSDART00000057101
aerolysin-like protein
chr19_+_791538 0.80 ENSDART00000146554
ENSDART00000138406
transmembrane protein 79a
chr1_+_12135129 0.77 ENSDART00000126020
serine peptidase inhibitor, Kazal type 4
chr21_-_22689805 0.77 ENSDART00000157560
ENSDART00000110792
grass carp reovirus (GCRV)-induced gene 2e
chr21_+_25226558 0.76 ENSDART00000168480
syncollin, tandem duplicate 2
chr1_-_58059134 0.76 ENSDART00000160970
caspase b
chr18_+_44703343 0.75 ENSDART00000131510
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2, like
chr19_+_48117995 0.74 ENSDART00000170865
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
chr22_+_5120033 0.73 ENSDART00000169200
muscle-specific beta 1 integrin binding protein
chr23_-_5719453 0.72 ENSDART00000033093
ladinin
chr23_+_39089574 0.72 ENSDART00000164711
nuclear factor of activated T cells 2a
chr25_+_10547228 0.71 ENSDART00000067678
zgc:110339
chr13_-_214122 0.71 ENSDART00000169273
protein phosphatase 1, regulatory subunit 21
chr18_-_5509616 0.71 ENSDART00000142945
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr5_+_4564233 0.70 ENSDART00000193435

chr21_-_42876565 0.68 ENSDART00000126480
zmp:0000001268
chr11_+_24729346 0.68 ENSDART00000087740
zgc:153953
chr21_-_25741096 0.68 ENSDART00000181756
claudin h
chr18_+_26422124 0.67 ENSDART00000060245
cathepsin H
chr21_-_10773344 0.67 ENSDART00000063244
gastrin-releasing peptide
chr15_-_17099560 0.67 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr7_-_55633475 0.67 ENSDART00000149478
galactosamine (N-acetyl)-6-sulfatase
chr6_+_112579 0.66 ENSDART00000034505
adaptor-related protein complex 1, mu 2 subunit
chr9_+_35077546 0.66 ENSDART00000142688
si:dkey-192g7.3
chr3_-_39488482 0.66 ENSDART00000135192
zgc:100868
chr3_-_39488639 0.66 ENSDART00000161644
zgc:100868
chr24_+_7631797 0.65 ENSDART00000187464
caveolae associated protein 1b
chr1_+_57145072 0.63 ENSDART00000152776
si:ch73-94k4.4
chr15_+_20403903 0.62 ENSDART00000134182
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr16_-_5143124 0.61 ENSDART00000131876
ENSDART00000060630
ttk protein kinase
chr5_+_4575800 0.61 ENSDART00000180952
cystatin 14b, tandem duplicate 2
chr5_-_1963498 0.60 ENSDART00000073462
ribosomal protein, large, P0
chr23_+_31913292 0.59 ENSDART00000136910
armadillo repeat containing 1, like
chr8_+_13389115 0.59 ENSDART00000184428
ENSDART00000154266
ENSDART00000049469
Janus kinase 3 (a protein tyrosine kinase, leukocyte)
chr7_+_39410180 0.58 ENSDART00000168641

chr3_-_13546610 0.57 ENSDART00000159647
amidohydrolase domain containing 2
chr19_-_15229421 0.57 ENSDART00000055619
phosphatase and actin regulator 4a
chr10_-_35149513 0.57 ENSDART00000063434
ENSDART00000131291
receptor-interacting serine-threonine kinase 4
chr25_-_19608382 0.56 ENSDART00000022279
ENSDART00000135201
ENSDART00000147223
ENSDART00000190220
ENSDART00000184242
ENSDART00000166824
G-2 and S-phase expressed 1
chr10_-_21953643 0.56 ENSDART00000188921
ENSDART00000193569

chr22_-_17653143 0.56 ENSDART00000089171
histocompatibility (minor) HA-1 b
chr7_+_46019780 0.56 ENSDART00000163991
cyclin E1
chr5_+_61475451 0.56 ENSDART00000163444
leucine-rich repeats and WD repeat domain containing 1
chr2_-_24069331 0.55 ENSDART00000156972
ENSDART00000181691
ENSDART00000157041
solute carrier family 12 (potassium/chloride transporter), member 7a
chr16_+_20895904 0.55 ENSDART00000052662
homeobox A13b
chr21_-_22715297 0.55 ENSDART00000065548
complement component 1, q subcomponent, B chain
chr24_+_42149453 0.55 ENSDART00000128766
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3
chr19_+_7895086 0.55 ENSDART00000132180
si:dkey-266f7.1
chr24_+_27511734 0.54 ENSDART00000105771
chemokine (C-X-C motif) ligand 32b, duplicate 1
chr7_-_11383933 0.54 ENSDART00000163949
mesoderm development LRP chaperone
chr17_-_24916889 0.54 ENSDART00000156157
si:ch211-195o20.7
chr7_-_11384279 0.54 ENSDART00000102515
ENSDART00000172796
mesoderm development LRP chaperone
chr3_-_18805225 0.54 ENSDART00000133471
ENSDART00000131758
methionine sulfoxide reductase B1a
chr7_+_39410393 0.53 ENSDART00000158561
ENSDART00000185173

chr15_-_4580763 0.52 ENSDART00000008170
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr6_+_392815 0.52 ENSDART00000163142
cytohesin 4b
chr22_+_978867 0.52 ENSDART00000148981
differentially expressed in FDCP 6b homolog (mouse)
chr18_+_44649804 0.52 ENSDART00000059063
EH-domain containing 2b
chr21_-_3007412 0.52 ENSDART00000190839
zgc:86839
chr24_-_42072886 0.52 ENSDART00000171389

chr3_-_4591643 0.52 ENSDART00000138144
finTRIM family, member 50
chr3_+_31662126 0.52 ENSDART00000113441
myosin, light chain kinase 5
chr22_+_29991834 0.51 ENSDART00000147728
si:dkey-286j15.3
chr12_+_37401331 0.51 ENSDART00000125040
si:ch211-152f22.4
chr8_+_8671229 0.51 ENSDART00000131963
ubiquitin specific peptidase 11
chr1_+_59538755 0.51 ENSDART00000166354
Sp6 transcription factor
chr19_+_19756425 0.51 ENSDART00000167606
homeobox A3a
chr3_-_3209432 0.51 ENSDART00000140635
si:ch211-229i14.2
chr13_+_22717366 0.50 ENSDART00000134122
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr23_+_32028574 0.50 ENSDART00000145501
ENSDART00000143121
ENSDART00000111877
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr25_+_19718504 0.50 ENSDART00000036702
myxovirus (influenza virus) resistance D
chr17_+_25331576 0.50 ENSDART00000157309
transmembrane protein 54a
chr3_+_19621034 0.49 ENSDART00000025358
integrin beta 3a
chr15_-_37850969 0.49 ENSDART00000031418
heat shock cognate 70
chr2_-_10877765 0.49 ENSDART00000100607
cell division cycle 7 homolog (S. cerevisiae)
chr7_-_59054322 0.49 ENSDART00000165390
charged multivesicular body protein 5b
chr15_+_1534644 0.49 ENSDART00000130413
structural maintenance of chromosomes 4
chr14_+_45471642 0.49 ENSDART00000126979
ENSDART00000172952
ENSDART00000173284
UBX domain protein 1
chr20_-_32045057 0.48 ENSDART00000152970
ENSDART00000034248
RAB32a, member RAS oncogene family
chr19_-_11336782 0.48 ENSDART00000131014
septin 7a
chr21_-_22669669 0.48 ENSDART00000101784
grass carp reovirus (GCRV)-induced gene 2j
chr10_-_15053507 0.48 ENSDART00000157446
ENSDART00000170441
si:ch211-95j8.5
chr1_+_14253118 0.48 ENSDART00000161996
chemokine (C-X-C motif) ligand 8a
chr11_+_10541258 0.47 ENSDART00000132365
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr15_-_28596507 0.47 ENSDART00000156800
si:ch211-225b7.5
chr5_+_26204561 0.47 ENSDART00000137178
MARVEL domain containing 2b
chr25_+_245438 0.46 ENSDART00000004689
zgc:92481
chr16_+_33143503 0.46 ENSDART00000058471
ENSDART00000179385
rhomboid, veinlet-like 2 (Drosophila)
chr21_-_3700334 0.46 ENSDART00000137844
ATPase phospholipid transporting 8B1
chr22_+_19494996 0.45 ENSDART00000140829
ENSDART00000135168
si:dkey-78l4.10
chr7_-_73717082 0.45 ENSDART00000164301
ENSDART00000082625

chr23_+_44644911 0.45 ENSDART00000140799
zgc:85858
chr3_+_16922226 0.45 ENSDART00000017646
ATPase H+ transporting V0 subunit a1a
chr7_-_6340998 0.45 ENSDART00000172884
zgc:165555
chr17_-_114121 0.45 ENSDART00000172408
ENSDART00000157784
Rho GTPase activating protein 11A
chr9_+_563547 0.45 ENSDART00000162761

chr14_+_23709543 0.44 ENSDART00000136909
glucosamine-6-phosphate deaminase 1
chr6_-_15641686 0.44 ENSDART00000135583
melanophilin a
chr11_-_270210 0.44 ENSDART00000005217
ENSDART00000172779
aminolevulinate, delta-, synthase 1
chr23_+_35847200 0.44 ENSDART00000129222
retinoic acid receptor gamma a
chr22_+_19478140 0.44 ENSDART00000135291
ENSDART00000136576
si:dkey-78l4.8
chr15_-_1198886 0.44 ENSDART00000063285
latexin
chr19_-_808265 0.44 ENSDART00000082454
glycosylated lysosomal membrane protein
chr7_+_49654588 0.44 ENSDART00000025451
ENSDART00000141934
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr7_+_53156810 0.43 ENSDART00000189816
cadherin 29
chr17_-_20143946 0.43 ENSDART00000138911
actinin, alpha 2b
chr7_-_5316901 0.43 ENSDART00000181505
ENSDART00000124367
si:cabz01074946.1
chr6_-_1761256 0.43 ENSDART00000171313
origin recognition complex, subunit 4
chr18_-_11729 0.43 ENSDART00000159781
WAS protein homolog associated with actin, golgi membranes and microtubules
chr8_+_41229233 0.42 ENSDART00000131135
zgc:152830
chr17_+_53425037 0.42 ENSDART00000154983
fatty acid binding protein 10b, liver basic
chr8_+_30797363 0.42 ENSDART00000077280
matrix metallopeptidase 11a
chr7_+_49695904 0.42 ENSDART00000183550
ENSDART00000126991
achaete-scute family bHLH transcription factor 1b
chr8_+_17167876 0.41 ENSDART00000134665
centromere protein H
chr15_-_43625549 0.41 ENSDART00000168589
cathepsin C
chr23_+_384850 0.41 ENSDART00000114000
zgc:101663
chr5_-_69944084 0.41 ENSDART00000188557
ENSDART00000127782
UDP glucuronosyltransferase 2 family, polypeptide A4
chr17_+_53424415 0.41 ENSDART00000157022
solute carrier family 9 member A1b
chr23_+_32039386 0.40 ENSDART00000133801
myosin light chain kinase 2
chr7_-_3669868 0.40 ENSDART00000172907
si:ch211-282j17.12
chr20_+_7584211 0.40 ENSDART00000132481
ENSDART00000127975
ENSDART00000144551
biogenesis of lysosomal organelles complex-1, subunit 2
chr10_+_36650222 0.40 ENSDART00000126963
uncoupling protein 3
chr7_-_3693303 0.40 ENSDART00000166949
si:ch211-282j17.13
chr10_+_36662640 0.40 ENSDART00000063359
uncoupling protein 2
chr9_+_36946340 0.39 ENSDART00000135281
si:dkey-3d4.3
chr19_+_7152966 0.39 ENSDART00000080348
bromodomain containing 2a
chr7_-_15118140 0.39 ENSDART00000179985
si:dkey-172h23.2
chr10_+_32050906 0.38 ENSDART00000137373
si:ch211-266i6.3
chr11_-_42730063 0.38 ENSDART00000169776
si:ch73-106k19.2
chr3_+_43086548 0.38 ENSDART00000163579
si:dkey-43p13.5
chr20_+_46213553 0.38 ENSDART00000100532
syntaxin 7-like
chr25_+_31323978 0.38 ENSDART00000067030
lymphocyte-specific protein 1
chr12_-_2800809 0.37 ENSDART00000152682
ENSDART00000083784
ubiquitin domain containing 1b
chr18_-_46280578 0.37 ENSDART00000131724
phospholipase D family, member 3
chr18_-_7539166 0.37 ENSDART00000133541
si:dkey-30c15.2
chr19_+_19762183 0.37 ENSDART00000163611
ENSDART00000187604
homeobox A3a
chr17_+_6563307 0.37 ENSDART00000156454
adhesion G protein-coupled receptor F3a
chr14_+_23709134 0.37 ENSDART00000191162
ENSDART00000179754
ENSDART00000054266
glucosamine-6-phosphate deaminase 1
chr8_+_17168114 0.37 ENSDART00000183901
centromere protein H
chr1_-_8140763 0.36 ENSDART00000091508
si:dkeyp-9d4.4
chr19_+_19772765 0.36 ENSDART00000182028
ENSDART00000161019
homeobox A3a
chr21_+_7298687 0.36 ENSDART00000187746

chr14_+_39156 0.36 ENSDART00000082184
transmembrane protein 107
chr1_+_57041549 0.36 ENSDART00000152198
si:ch211-1f22.16
chr2_+_24507597 0.36 ENSDART00000133109
ribosomal protein S28
chr5_-_54714789 0.36 ENSDART00000063357
cyclin B1
chr1_-_18811517 0.36 ENSDART00000142026
si:dkey-167i21.2
chr8_-_20245892 0.36 ENSDART00000136911
alkaline ceramidase 1
chr25_+_258883 0.36 ENSDART00000155256
zgc:92481
chr3_+_23710839 0.36 ENSDART00000151584
homeobox B4a
chr14_+_94946 0.36 ENSDART00000165766
ENSDART00000163778
minichromosome maintenance complex component 7
chr19_+_48176745 0.36 ENSDART00000164963
PR domain containing 1b, with ZNF domain
chr6_+_153146 0.35 ENSDART00000097468
zinc finger, GATA-like protein 1
chr18_-_7539469 0.35 ENSDART00000101296
si:dkey-30c15.2
chr4_+_5341592 0.35 ENSDART00000123375
ENSDART00000067371
zgc:113263
chr4_-_42242844 0.35 ENSDART00000163476
si:ch211-129p6.2
chr3_-_34098731 0.35 ENSDART00000150999
immunoglobulin heavy variable 5-3
chr20_+_32406011 0.34 ENSDART00000018640
ENSDART00000137910
sorting nexin 3
chr2_-_10386738 0.34 ENSDART00000016369
wntless Wnt ligand secretion mediator
chr23_+_45025909 0.34 ENSDART00000188105
high mobility group box 2b
chr20_+_192170 0.34 ENSDART00000189675
connexin 28.8
chr3_-_8765165 0.33 ENSDART00000191131

chr14_+_22076596 0.33 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
solute carrier family 43 (amino acid system L transporter), member 1a
chr14_+_41318881 0.33 ENSDART00000192137
XK, Kell blood group complex subunit-related, X-linked
chr6_+_12968101 0.33 ENSDART00000013781
minichromosome maintenance complex component 6
chr4_-_13614797 0.33 ENSDART00000138366
ENSDART00000165212
interferon regulatory factor 5
chr19_-_1855368 0.33 ENSDART00000029646
ribosomal protein, large, P1
chr11_-_42472941 0.33 ENSDART00000166624
ADP-ribosylation factor 4b
chr17_+_30843881 0.33 ENSDART00000149600
ENSDART00000148547
tripeptidyl peptidase I
chr3_+_61391636 0.33 ENSDART00000126417
brain protein I3
chr9_+_55857193 0.33 ENSDART00000160980
septin 10
chr14_+_8456870 0.33 ENSDART00000007738
transmembrane and coiled-coil domains 6
chr17_+_32622933 0.33 ENSDART00000077418
cathepsin Ba
chr19_+_10493607 0.32 ENSDART00000003031
si:ch211-171h4.6
chr15_+_6652396 0.32 ENSDART00000192813
ENSDART00000157678
NOP53 ribosome biogenesis factor
chr4_-_68853063 0.32 ENSDART00000162386
si:dkey-264f17.1

Network of associatons between targets according to the STRING database.

First level regulatory network of tfe3a+tfe3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:1901994 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.3 1.3 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.2 0.9 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.2 1.1 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.2 1.4 GO:0060017 parathyroid gland development(GO:0060017)
0.2 0.5 GO:0002544 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.2 0.9 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 0.6 GO:0070199 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.1 1.4 GO:0030104 water homeostasis(GO:0030104)
0.1 0.6 GO:0030101 natural killer cell activation(GO:0030101)
0.1 0.4 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.3 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.3 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.7 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 0.6 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.3 GO:0019626 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.1 0.3 GO:0051503 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 0.2 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.1 0.2 GO:0032677 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.1 0.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.5 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.3 GO:0089709 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.6 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.2 GO:0065001 specification of axis polarity(GO:0065001)
0.1 0.3 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.1 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 1.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 0.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852) water-soluble vitamin biosynthetic process(GO:0042364)
0.1 0.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.3 GO:0051182 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.1 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.2 GO:0016139 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.1 0.6 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.2 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.3 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.1 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.1 1.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.8 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.8 GO:0051382 kinetochore assembly(GO:0051382)
0.0 1.0 GO:0015671 oxygen transport(GO:0015671)
0.0 0.9 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.7 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 1.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.7 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.8 GO:0032438 melanosome organization(GO:0032438)
0.0 1.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:1903358 regulation of Golgi organization(GO:1903358)
0.0 0.1 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.0 0.3 GO:0021561 facial nerve development(GO:0021561)
0.0 0.1 GO:0051039 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.9 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.4 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.3 GO:0046546 development of primary male sexual characteristics(GO:0046546)
0.0 0.2 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.8 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 1.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.1 GO:0090148 membrane fission(GO:0090148)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.5 GO:0090224 regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.0 0.4 GO:0001845 phagolysosome assembly(GO:0001845)
0.0 0.2 GO:0055016 hypochord development(GO:0055016)
0.0 0.2 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.5 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.5 GO:0042026 protein refolding(GO:0042026)
0.0 0.4 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.4 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.2 GO:0035513 oxidative RNA demethylation(GO:0035513)
0.0 0.1 GO:0071514 genetic imprinting(GO:0071514)
0.0 0.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:1903332 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.0 0.4 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.3 GO:0030719 P granule organization(GO:0030719)
0.0 0.8 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0070914 nucleotide-excision repair, DNA gap filling(GO:0006297) UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0098773 ventricular trabecula myocardium morphogenesis(GO:0003222) trabecula formation(GO:0060343) heart trabecula formation(GO:0060347) skin epidermis development(GO:0098773)
0.0 0.2 GO:0034205 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.5 GO:1903051 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) negative regulation of proteasomal protein catabolic process(GO:1901799) negative regulation of proteolysis involved in cellular protein catabolic process(GO:1903051)
0.0 0.2 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 1.7 GO:0051607 defense response to virus(GO:0051607)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.8 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.4 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.2 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0009098 leucine biosynthetic process(GO:0009098)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.7 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.1 GO:0009092 homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) transsulfuration(GO:0019346)
0.0 0.3 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.4 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.3 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.0 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0090299 regulation of neural crest formation(GO:0090299)
0.0 0.9 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0 0.0 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.5 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.3 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.1 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.6 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.1 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.0 0.7 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.2 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.0 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.3 GO:0008272 sulfate transport(GO:0008272)
0.0 0.3 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.0 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0 0.2 GO:0016075 rRNA catabolic process(GO:0016075)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.2 0.7 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 0.8 GO:0061702 inflammasome complex(GO:0061702)
0.1 0.6 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.5 GO:0005880 nuclear microtubule(GO:0005880)
0.1 1.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.6 GO:0032797 SMN complex(GO:0032797)
0.1 0.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.2 GO:0033391 chromatoid body(GO:0033391)
0.1 0.2 GO:0005775 vacuolar lumen(GO:0005775) lysosomal lumen(GO:0043202)
0.1 0.2 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.1 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.0 0.3 GO:0035101 FACT complex(GO:0035101)
0.0 0.2 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.8 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.8 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0030428 cell septum(GO:0030428)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 1.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0072380 TRC complex(GO:0072380)
0.0 0.3 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 1.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.5 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 1.5 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.4 GO:0070187 telosome(GO:0070187)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.2 GO:0071546 pi-body(GO:0071546)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 0.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.6 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.9 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 0.5 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.4 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.0 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0016234 inclusion body(GO:0016234)
0.0 0.3 GO:0000776 kinetochore(GO:0000776)
0.0 0.0 GO:0098842 postsynaptic early endosome(GO:0098842)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0048030 disaccharide binding(GO:0048030)
0.2 0.7 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.2 0.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.2 0.7 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 0.6 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.2 0.5 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.4 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.7 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.4 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.5 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.1 0.3 GO:0034618 arginine binding(GO:0034618)
0.1 0.7 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.6 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 1.0 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.8 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.4 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 0.4 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 0.2 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.1 0.3 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 0.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.3 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.2 GO:0019777 Atg12 transferase activity(GO:0019777)
0.1 0.2 GO:0042806 fucose binding(GO:0042806)
0.1 0.9 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.3 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.3 GO:0009374 biotin binding(GO:0009374)
0.1 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0003913 DNA photolyase activity(GO:0003913)
0.0 2.4 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0035516 oxidative DNA demethylase activity(GO:0035516)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.0 0.8 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.6 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0030250 calcium sensitive guanylate cyclase activator activity(GO:0008048) cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.1 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.6 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0004903 growth hormone receptor activity(GO:0004903)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.8 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0035804 structural constituent of egg coat(GO:0035804)
0.0 0.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 3.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 0.2 GO:2001069 glycogen binding(GO:2001069)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.5 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.7 GO:0003823 antigen binding(GO:0003823)
0.0 1.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.0 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.1 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0031491 nucleosome binding(GO:0031491)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.9 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.9 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.4 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.3 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 3.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.8 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 1.1 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.6 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.5 REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX Genes involved in Formation of RNA Pol II elongation complex
0.0 0.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism