Project

PRJNA207719: Tissue specific transcriptome profiling

Navigation
Downloads

Results for tfap4

Z-value: 1.75

Motif logo

Transcription factors associated with tfap4

Gene Symbol Gene ID Gene Info
ENSDARG00000103923 transcription factor AP-4 (activating enhancer binding protein 4)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tfap4dr11_v1_chr3_-_12227359_122273590.434.7e-01Click!

Activity profile of tfap4 motif

Sorted Z-values of tfap4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr25_-_4482449 1.74 ENSDART00000056278
ENSDART00000149425
solute carrier family 25 member 22a
chr13_+_36764715 1.49 ENSDART00000111832
ENSDART00000085230
atlastin GTPase 1
chr23_+_35714574 1.29 ENSDART00000164616
tubulin, alpha 1c
chr5_+_71999996 1.22 ENSDART00000179933
ENSDART00000187070
phospholipid phosphatase 7 (inactive)
chr21_-_43952958 1.17 ENSDART00000039571
calcium/calmodulin-dependent protein kinase II alpha
chr15_+_40188076 1.08 ENSDART00000063779
EF-hand domain family, member D1
chr1_-_14233815 1.07 ENSDART00000044896
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr20_-_29864390 1.06 ENSDART00000161834
ENSDART00000132278
ring finger protein 144ab
chr1_+_25801648 1.03 ENSDART00000129471
guanylate cyclase 1 soluble subunit beta 1
chr20_+_35382482 1.03 ENSDART00000135284
visinin-like 1a
chr15_+_29088426 1.00 ENSDART00000187290
si:ch211-137a8.4
chr18_+_38908903 0.99 ENSDART00000159834
myosin VAa
chr1_-_26131088 0.98 ENSDART00000193973
ENSDART00000054209
cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4)
chr25_+_35250976 0.98 ENSDART00000003494
solute carrier family 17 (vesicular glutamate transporter), member 6a
chr14_-_32016615 0.98 ENSDART00000105761
zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)
chr19_+_1184878 0.96 ENSDART00000163539
scratch family zinc finger 1a
chr13_-_30028103 0.95 ENSDART00000183889
stearoyl-CoA desaturase b
chr1_-_26782573 0.93 ENSDART00000090611
SH3 domain containing GRB2 like 2a, endophilin A1
chr2_+_6181383 0.89 ENSDART00000153307
si:ch73-344o19.1
chr5_-_2636078 0.88 ENSDART00000122274
citron rho-interacting serine/threonine kinase a
chr3_-_32320537 0.87 ENSDART00000113550
ENSDART00000168483
si:dkey-16p21.7
chr4_+_25950372 0.84 ENSDART00000125767
methionyl aminopeptidase 2a
chr6_-_43092175 0.83 ENSDART00000084389
leucine rich repeat neuronal 1
chr6_+_18520859 0.81 ENSDART00000158263
si:dkey-10p5.10
chr18_-_46208581 0.79 ENSDART00000141278
si:ch211-14c7.2
chr22_-_16443199 0.79 ENSDART00000006290
ENSDART00000193335
pleckstrin homology domain containing, family B (evectins) member 2
chr22_+_17203752 0.78 ENSDART00000143376
RAB3B, member RAS oncogene family
chr16_-_31188715 0.77 ENSDART00000058829
scratch family zinc finger 1b
chr23_+_23182037 0.77 ENSDART00000137353
kelch-like family member 17
chr13_-_30027730 0.77 ENSDART00000044009
stearoyl-CoA desaturase b
chr12_-_47601845 0.76 ENSDART00000169548
ENSDART00000182889
regulator of G protein signaling 7b
chr3_-_62380146 0.76 ENSDART00000155853
G protein-coupled receptor, class C, group 5, member Ba
chr16_+_52748263 0.75 ENSDART00000032275
ATPase H+ transporting V1 subunit C1a
chr8_-_22639794 0.75 ENSDART00000188029
IQ motif and Sec7 domain 2a
chr4_-_5247335 0.75 ENSDART00000050221
ATPase H+ transporting V1 subunit E1b
chr3_+_54168007 0.74 ENSDART00000109894
olfactomedin 2a
chr21_+_13205859 0.74 ENSDART00000102253
spectrin alpha, non-erythrocytic 1
chr19_-_32150078 0.74 ENSDART00000134934
ENSDART00000186410
ENSDART00000181780
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
chr5_-_21065094 0.73 ENSDART00000143785
si:dkey-13n15.2
chr4_+_20255160 0.73 ENSDART00000188658
leucine-rich repeats and transmembrane domains 2a
chr10_+_15777258 0.72 ENSDART00000140511
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr13_+_42124566 0.72 ENSDART00000074707
CDC42 effector protein (Rho GTPase binding) 3
chr7_-_41964877 0.72 ENSDART00000092351
ENSDART00000193395
ENSDART00000187947
neuropilin (NRP) and tolloid (TLL)-like 2b
chr2_-_22286828 0.72 ENSDART00000168653
family with sequence similarity 110, member B
chr1_+_41666611 0.72 ENSDART00000145789
F-box protein 41
chr15_-_18432673 0.72 ENSDART00000146853
neural cell adhesion molecule 1b
chr21_-_16632808 0.71 ENSDART00000172645
unc-5 netrin receptor Da
chr21_-_43015383 0.70 ENSDART00000065097
dihydropyrimidinase-like 3
chr13_-_27675212 0.70 ENSDART00000141035
regulating synaptic membrane exocytosis 1a
chr25_+_19999623 0.69 ENSDART00000026401
zgc:194665
chr14_+_30730749 0.69 ENSDART00000087884
coiled-coil domain containing 85B
chr24_+_24461558 0.68 ENSDART00000182424
basic helix-loop-helix family, member e22
chr3_-_40836081 0.67 ENSDART00000143135
WD repeat domain, phosphoinositide interacting 2
chr5_-_21030934 0.67 ENSDART00000133461
ENSDART00000098667
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr19_+_32947910 0.67 ENSDART00000052091
ATPase H+ transporting V1 subunit C1b
chr13_+_16521898 0.67 ENSDART00000122557
potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr22_+_21618121 0.66 ENSDART00000133939
transducin like enhancer of split 2a
chr6_+_46431848 0.65 ENSDART00000181056
ENSDART00000144569
ENSDART00000064865
ENSDART00000133992
staufen double-stranded RNA binding protein 1
chr14_+_21783229 0.65 ENSDART00000170784
ankyrin repeat domain 13 family, member D
chr25_-_35542739 0.64 ENSDART00000097651
si:ch211-87j1.4
chr8_+_1082100 0.64 ENSDART00000149276
leucine zipper, putative tumor suppressor family member 3b
chr12_-_29624638 0.64 ENSDART00000126744
neuregulin 3b
chr14_+_34068075 0.64 ENSDART00000135556
LON peptidase N-terminal domain and ring finger 1
chr14_+_21783400 0.63 ENSDART00000164023
ankyrin repeat domain 13 family, member D
chr14_-_32258759 0.63 ENSDART00000052949
fibroblast growth factor 13a
chr9_-_889567 0.63 ENSDART00000155921
si:ch73-250a16.5
chr23_-_16692312 0.63 ENSDART00000046784
FK506 binding protein 1Ab
chr12_+_33038757 0.63 ENSDART00000153146
RNA binding fox-1 homolog 3a
chr10_+_15777064 0.63 ENSDART00000114483
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr9_-_43375205 0.63 ENSDART00000138436
zinc finger protein 385B
chr10_-_24371312 0.62 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr7_+_427503 0.62 ENSDART00000185942
neurexin 2
chr5_+_24245682 0.61 ENSDART00000049003
ATPase H+ transporting V1 subunit Aa
chr3_+_15817644 0.61 ENSDART00000055787
zgc:110779
chr6_+_59818275 0.61 ENSDART00000165213
calcium/calmodulin-dependent serine protein kinase b
chr21_+_26726936 0.60 ENSDART00000065392
calmodulin 2a (phosphorylase kinase, delta)
chr2_+_37480669 0.60 ENSDART00000029801
signal peptide peptidase-like 2
chr12_-_45669050 0.60 ENSDART00000124455
F-box and leucine-rich repeat protein 15
chr18_-_898870 0.59 ENSDART00000151777
ENSDART00000062654
poly (ADP-ribose) polymerase family, member 6a
chr9_+_38168012 0.59 ENSDART00000102445
cytoplasmic linker associated protein 1a
chr8_+_7144066 0.59 ENSDART00000146306
solute carrier family 6 (neurotransmitter transporter), member 6a
chr10_-_34870667 0.59 ENSDART00000161272
doublecortin-like kinase 1a
chr23_-_29667544 0.58 ENSDART00000059339
calsyntenin 1
chr6_-_6775821 0.58 ENSDART00000141126
ENSDART00000106610
coiled-coil domain containing 85A, like
chr9_+_13733468 0.58 ENSDART00000165954
ENSDART00000160355
ENSDART00000081040
ENSDART00000138254
ENSDART00000081015
ENSDART00000141314
abl-interactor 2a
chr21_+_32332616 0.58 ENSDART00000154105
si:ch211-247j9.1
chr14_-_32744464 0.58 ENSDART00000075617
SRY (sex determining region Y)-box 3
chr18_-_50862939 0.57 ENSDART00000180407

chr9_-_23824290 0.57 ENSDART00000059209
WD repeat and FYVE domain containing 2
chr10_+_399363 0.56 ENSDART00000147449
si:ch211-242f23.8
chr2_-_37059966 0.56 ENSDART00000137967
DIRAS family, GTP-binding RAS-like 1b
chr21_+_39361040 0.56 ENSDART00000085453
clustered mitochondria (cluA/CLU1) homolog b
chr15_+_22435460 0.55 ENSDART00000031976
transmembrane protein 136a
chr1_-_54997746 0.55 ENSDART00000152666
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23a
chr9_+_51891 0.55 ENSDART00000163529
zgc:158316
chr5_+_57320113 0.54 ENSDART00000036331
ATPase H+ transporting V1 subunit G1
chr15_-_20949692 0.54 ENSDART00000185548
tubulin folding cofactor E-like a
chr9_+_33154841 0.53 ENSDART00000132465
dopey family member 2
chr16_-_23372666 0.53 ENSDART00000158786
tripartite motif containing 46a
chr10_-_11840353 0.53 ENSDART00000127581
tripartite motif containing 23
chr5_+_42912966 0.53 ENSDART00000039973
RUN and FYVE domain containing 3
chr22_+_34430310 0.53 ENSDART00000109860
adhesion molecule with Ig-like domain 3
chr23_-_36724575 0.53 ENSDART00000159560
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr10_+_34315719 0.53 ENSDART00000135303
StAR-related lipid transfer (START) domain containing 13a
chr6_+_4872883 0.52 ENSDART00000186730
ENSDART00000092290
ENSDART00000151674
protocadherin 9
chr18_+_16960966 0.52 ENSDART00000193969
ENSDART00000100131
si:ch211-242e8.1
chr13_+_1575276 0.52 ENSDART00000165987
dystonin
chr5_+_39994283 0.51 ENSDART00000112728
transmembrane protein 175
chr12_+_19036380 0.51 ENSDART00000153086
ENSDART00000181060
potassium channel tetramerization domain containing 17
chr3_-_29968015 0.51 ENSDART00000077119
ENSDART00000139310
branched chain amino-acid transaminase 2, mitochondrial
chr19_-_28789404 0.51 ENSDART00000191453
ENSDART00000026992
SRY (sex determining region Y)-box 4a
chr1_-_45920632 0.50 ENSDART00000140890
patatin-like phospholipase domain containing 6
chr4_+_26496489 0.50 ENSDART00000160652
IQ motif and Sec7 domain 3a
chr5_+_30624183 0.50 ENSDART00000141444
ATP-binding cassette, sub-family G (WHITE), member 4a
chr18_+_43183749 0.50 ENSDART00000151166
nectin cell adhesion molecule 1b
chr20_-_45423498 0.49 ENSDART00000098424
tribbles pseudokinase 2
chr20_+_18580176 0.48 ENSDART00000185310
si:dkeyp-72h1.1
chr21_-_7178348 0.48 ENSDART00000187467
family with sequence similarity 69, member B
chr20_-_25878586 0.48 ENSDART00000153347
ENSDART00000063154
exocyst complex component 1
chr6_+_59991076 0.48 ENSDART00000163575

chr18_-_25905574 0.47 ENSDART00000143899
ENSDART00000163369
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Ba
chr1_-_25911292 0.47 ENSDART00000145012
ubiquitin specific peptidase 53b
chr18_+_39028417 0.47 ENSDART00000148428
myosin VAa
chr18_+_39074139 0.47 ENSDART00000142390
guanine nucleotide binding protein (G protein), beta 5b
chr16_-_30655980 0.46 ENSDART00000146508
low density lipoprotein receptor class A domain containing 4b
chr8_-_50981175 0.46 ENSDART00000004065
zgc:91909
chr2_+_31957554 0.46 ENSDART00000012413
ANKH inorganic pyrophosphate transport regulator b
chr5_+_31779911 0.46 ENSDART00000098163
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25b
chr20_+_54280549 0.46 ENSDART00000151048
ARP10 actin related protein 10 homolog
chr8_+_25254435 0.46 ENSDART00000143554
adenosine monophosphate deaminase 2b
chr4_+_15605844 0.46 ENSDART00000101619
ENSDART00000021384
exocyst complex component 4
chr4_-_20051141 0.46 ENSDART00000066963
ATPase H+ transporting V1 subunit F
chr20_+_20731052 0.46 ENSDART00000047662
protein phosphatase 1, regulatory subunit 13Bb
chr12_-_17147473 0.45 ENSDART00000106035
STAM binding protein-like 1
chr14_+_16083818 0.45 ENSDART00000168462
ring finger protein 103
chr3_-_51912019 0.45 ENSDART00000149914
apoptosis-associated tyrosine kinase a
chr14_-_48939560 0.44 ENSDART00000021736
short coiled-coil protein b
chr12_-_33359654 0.44 ENSDART00000001907
solute carrier family 16 (monocarboxylate transporter), member 3
chr11_+_45448212 0.44 ENSDART00000173341
son of sevenless homolog 1 (Drosophila)
chr10_-_6867282 0.44 ENSDART00000144001
ENSDART00000109744
diphosphoinositol pentakisphosphate kinase 2
chr2_+_47623202 0.44 ENSDART00000154465
si:ch211-165b10.3
chr10_-_20481763 0.43 ENSDART00000091156
ENSDART00000192358
transforming, acidic coiled-coil containing protein 1
chr10_+_1849874 0.43 ENSDART00000158897
ENSDART00000149956
adenomatous polyposis coli
chr10_+_3875716 0.43 ENSDART00000189268
ENSDART00000180624
tetratricopeptide repeat domain 28
chr20_+_9781932 0.42 ENSDART00000053841
DDHD domain containing 1b
chr7_+_26224211 0.42 ENSDART00000173999
VGF nerve growth factor inducible
chr1_+_49686408 0.42 ENSDART00000140824
si:ch211-149l1.2
chr9_-_52678146 0.41 ENSDART00000169179
phosphofructokinase, liver a
chr5_-_51819027 0.41 ENSDART00000164267
homer scaffolding protein 1b
chr17_+_23964132 0.41 ENSDART00000154823
exportin 1 (CRM1 homolog, yeast) b
chr3_+_51563695 0.41 ENSDART00000008607
tweety homolog 2, like
chr7_-_40578733 0.41 ENSDART00000173926
ENSDART00000010035
DnaJ (Hsp40) homolog, subfamily B, member 6b
chr8_+_29749017 0.41 ENSDART00000185144
mitogen-activated protein kinase 4
chr21_-_12030654 0.41 ENSDART00000139145
tubulin polyglutamylase complex subunit 2
chr20_-_51100669 0.40 ENSDART00000023488
ATPase H+ transporting V1 subunit D
chr4_-_5597167 0.40 ENSDART00000132431
vascular endothelial growth factor Ab
chr21_-_31143903 0.40 ENSDART00000111571
RAP1 GTPase activating protein 2b
chr19_-_10214264 0.40 ENSDART00000053300
ENSDART00000148225
zinc finger protein 865
chr9_+_31556043 0.40 ENSDART00000140220
si:ch211-168k14.2
chr8_+_52701811 0.40 ENSDART00000179692
BCL2 like 16
chr18_+_25003207 0.40 ENSDART00000099476
ENSDART00000132285
family with sequence similarity 174, member B
chr12_-_25150239 0.40 ENSDART00000038415
ENSDART00000135368
ras homolog family member Q
chr13_-_8446341 0.39 ENSDART00000080382
endothelial PAS domain protein 1b
chr21_-_35324091 0.39 ENSDART00000185042
ubiquitin-like domain containing CTD phosphatase 1
chr14_-_25577094 0.39 ENSDART00000163669
complexin 2
chr16_-_263658 0.39 ENSDART00000129303
solute carrier family 6 (neurotransmitter transporter), member 3
chr22_+_24157807 0.39 ENSDART00000159165
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr17_+_23968214 0.39 ENSDART00000183053
exportin 1 (CRM1 homolog, yeast) b
chr19_+_21408709 0.39 ENSDART00000186194
teashirt zinc finger homeobox 1
chr8_+_53311965 0.38 ENSDART00000130104
guanine nucleotide binding protein (G protein), beta polypeptide 1a
chr13_-_40499296 0.38 ENSDART00000158338
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr3_-_28075756 0.38 ENSDART00000122037
RNA binding fox-1 homolog 1
chr3_+_14317802 0.38 ENSDART00000162023
phospholipid phosphatase related 2a
chr13_+_22119798 0.38 ENSDART00000173206
ENSDART00000078652
ENSDART00000165842
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2
chr12_-_3840664 0.38 ENSDART00000160967
TAO kinase 2b
chr14_+_25986895 0.38 ENSDART00000149087
solute carrier family 36 (proton/amino acid symporter), member 1
chr21_-_24865217 0.38 ENSDART00000101136
immunoglobulin superfamily, member 9Bb
chr23_+_21638258 0.37 ENSDART00000104188
immunoglobin superfamily, member 21b
chr24_-_30091937 0.37 ENSDART00000148249
phospholipid phosphatase related 4b
chr5_-_48995955 0.37 ENSDART00000074592
arrestin domain containing 3a
chr18_-_1228688 0.37 ENSDART00000064403
neuroplastin b
chr10_+_40160502 0.36 ENSDART00000171879
GRAM domain containing 1Ba
chr11_+_30161699 0.36 ENSDART00000190504
cyclin-dependent kinase-like 5
chr10_+_10738880 0.36 ENSDART00000004181
solute carrier family 27 (fatty acid transporter), member 4
chr11_+_30161168 0.36 ENSDART00000157385
cyclin-dependent kinase-like 5
chr17_-_38887424 0.36 ENSDART00000141177
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4a
chr19_+_4463389 0.36 ENSDART00000168805
potassium channel, subfamily K, member 9
chr7_-_24390879 0.36 ENSDART00000036680
prostaglandin reductase 1
chr8_-_4010887 0.35 ENSDART00000163678
myotubularin related protein 3
chr25_-_29987839 0.35 ENSDART00000154088
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5b
chr20_-_26421112 0.35 ENSDART00000183767
ENSDART00000182330
A kinase (PRKA) anchor protein 12b
chr14_-_15699528 0.35 ENSDART00000161123
neuralized E3 ubiquitin protein ligase 1B
chr22_+_30335936 0.34 ENSDART00000059923
max interactor 1, dimerization protein
chr20_-_26467307 0.34 ENSDART00000078072
ENSDART00000158213
A kinase (PRKA) anchor protein 12b
chr12_-_41662327 0.34 ENSDART00000191602
ENSDART00000170423
Janus kinase and microtubule interacting protein 3
chr3_+_22935183 0.34 ENSDART00000157378
histone deacetylase 5
chr18_+_6479963 0.34 ENSDART00000092752
ENSDART00000136333
WAS protein family homolog 1
chr15_-_16177603 0.33 ENSDART00000156352
si:ch211-259g3.4
chr13_+_22317216 0.33 ENSDART00000110794
ubiquitin specific peptidase 54a
chr13_+_1928361 0.33 ENSDART00000164764
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of tfap4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.3 1.0 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.3 1.0 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.2 0.8 GO:0070084 protein initiator methionine removal(GO:0070084)
0.2 0.8 GO:0009098 leucine biosynthetic process(GO:0009098)
0.2 0.4 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.2 1.7 GO:0015800 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.2 0.5 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.2 0.5 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.2 0.5 GO:0044650 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.2 1.5 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.4 GO:0015874 norepinephrine transport(GO:0015874)
0.1 0.4 GO:0015808 L-alanine transport(GO:0015808) proline transport(GO:0015824)
0.1 1.0 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.6 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.6 GO:0061551 trigeminal ganglion development(GO:0061551)
0.1 0.4 GO:1905067 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.1 0.8 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 0.6 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 1.1 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 0.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.5 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.3 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.4 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.1 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.1 0.5 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.9 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.4 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 0.7 GO:0031274 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.3 GO:1900136 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 0.5 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.3 GO:0099623 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.1 0.7 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.2 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.2 GO:0036316 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.2 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 0.6 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.2 GO:0090299 regulation of neural crest formation(GO:0090299)
0.1 0.2 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.1 0.3 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 1.6 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.2 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.3 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.1 GO:0035046 pronuclear migration(GO:0035046)
0.0 0.7 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.4 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.1 GO:1903332 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.2 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
0.0 0.3 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.3 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.6 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.7 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.3 GO:0043304 mast cell activation involved in immune response(GO:0002279) mast cell mediated immunity(GO:0002448) regulation of mast cell activation involved in immune response(GO:0033006) leukocyte degranulation(GO:0043299) regulation of leukocyte degranulation(GO:0043300) mast cell degranulation(GO:0043303) regulation of mast cell degranulation(GO:0043304)
0.0 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.6 GO:0043507 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.4 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.2 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.3 GO:0021871 forebrain regionalization(GO:0021871)
0.0 0.1 GO:0010660 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.5 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.5 GO:0032264 IMP salvage(GO:0032264)
0.0 0.2 GO:0061162 establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.6 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.6 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.9 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.2 GO:0016081 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.0 1.2 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.0 0.3 GO:0061620 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097) negative regulation of autophagosome assembly(GO:1902902)
0.0 0.3 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0044783 G1 DNA damage checkpoint(GO:0044783)
0.0 0.2 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 1.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0061709 reticulophagy(GO:0061709)
0.0 0.1 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 1.1 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.5 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.3 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.5 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.2 GO:0031937 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.7 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.4 GO:0014029 neural crest formation(GO:0014029)
0.0 0.7 GO:0050868 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 1.1 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.6 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.6 GO:0090307 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.1 GO:0035777 pronephric distal tubule development(GO:0035777)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.4 GO:0043049 otic placode formation(GO:0043049)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.8 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.2 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.5 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0046887 positive regulation of hormone secretion(GO:0046887)
0.0 0.2 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121) respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.5 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0030901 midbrain development(GO:0030901)
0.0 0.4 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.7 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 1.1 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.1 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.0 0.3 GO:0072114 pronephros morphogenesis(GO:0072114)
0.0 0.5 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.3 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.8 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0044154 histone H3-K14 acetylation(GO:0044154)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0033268 node of Ranvier(GO:0033268)
0.2 0.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 0.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.6 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.9 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.8 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.5 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.8 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.1 0.3 GO:1990745 EARP complex(GO:1990745)
0.1 0.5 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.2 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.3 GO:0071203 WASH complex(GO:0071203)
0.1 1.0 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0072380 TRC complex(GO:0072380)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 1.0 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.9 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 1.3 GO:0030426 growth cone(GO:0030426)
0.0 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.4 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 2.6 GO:0005770 late endosome(GO:0005770)
0.0 0.5 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 1.7 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.2 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 3.9 GO:0005912 adherens junction(GO:0005912)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.1 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0032896 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.2 0.8 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 0.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 0.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 2.7 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 0.4 GO:0005333 dopamine transmembrane transporter activity(GO:0005329) dopamine:sodium symporter activity(GO:0005330) norepinephrine transmembrane transporter activity(GO:0005333) norepinephrine:sodium symporter activity(GO:0005334)
0.1 0.4 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.4 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 2.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.5 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.1 0.3 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 0.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.3 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 3.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.7 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.6 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.7 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 1.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.9 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 1.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.3 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 0.3 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.2 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.0 0.2 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.7 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0070728 leucine binding(GO:0070728)
0.0 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 1.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.0 0.9 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.3 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.8 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 1.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.5 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0070095 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 1.0 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 1.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882) structural constituent of synapse(GO:0098918)
0.0 0.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.6 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.8 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:1990931 RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.6 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.0 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.1 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.9 PID INSULIN PATHWAY Insulin Pathway
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.7 PID SHP2 PATHWAY SHP2 signaling
0.0 0.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 0.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.9 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway