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PRJNA207719: Tissue specific transcriptome profiling

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Results for tcf3a+tcf3b

Z-value: 1.62

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Transcription factors associated with tcf3a+tcf3b

Gene Symbol Gene ID Gene Info
ENSDARG00000005915 transcription factor 3a
ENSDARG00000099999 transcription factor 3b
ENSDARG00000112646 transcription factor 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tcf3adr11_v1_chr2_-_57378748_57378748-0.553.3e-01Click!
tcf3bdr11_v1_chr22_-_20342260_20342260-0.039.6e-01Click!

Activity profile of tcf3a+tcf3b motif

Sorted Z-values of tcf3a+tcf3b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_11756040 1.71 ENSDART00000105808
keratin 97
chr22_+_11775269 1.01 ENSDART00000140272
keratin 96
chr23_-_5683147 0.93 ENSDART00000102766
ENSDART00000067351
troponin T type 2a (cardiac)
chr8_+_1009831 0.79 ENSDART00000172414
fatty acid binding protein 1b, liver, tandem duplicate 2
chr23_+_25893020 0.75 ENSDART00000144769
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr13_-_438705 0.74 ENSDART00000082142

chr14_+_31651533 0.72 ENSDART00000172835
four and a half LIM domains 1a
chr22_-_10541372 0.71 ENSDART00000179708
si:dkey-42i9.4
chr7_+_31838320 0.70 ENSDART00000144679
ENSDART00000174217
ENSDART00000122506
myosin binding protein C, cardiac
chr4_-_4834347 0.69 ENSDART00000141803
cytochrome c oxidase assembly factor 6
chr2_-_42128714 0.69 ENSDART00000047055
tripartite motif containing 55a
chr16_+_813780 0.68 ENSDART00000162474
ENSDART00000161774
iroquois homeobox 1a
chr23_-_10177442 0.66 ENSDART00000144280
ENSDART00000129044
keratin 5
chr8_-_1051438 0.66 ENSDART00000067093
ENSDART00000170737
SET and MYND domain containing 1b
chr22_+_16308806 0.65 ENSDART00000162685
leucine rich repeat containing 39
chr3_-_29962345 0.63 ENSDART00000136819
branched chain amino-acid transaminase 2, mitochondrial
chr20_-_9436521 0.62 ENSDART00000133000
zgc:101840
chr6_-_35439406 0.61 ENSDART00000073784
regulator of G protein signaling 5a
chr22_+_16308450 0.59 ENSDART00000105678
leucine rich repeat containing 39
chr6_-_42003780 0.58 ENSDART00000032527
caveolin 3
chr7_+_31891110 0.58 ENSDART00000173883
myosin binding protein C, cardiac
chr19_-_11336782 0.58 ENSDART00000131014
septin 7a
chr18_-_14337065 0.57 ENSDART00000135703
heat shock factor binding protein 1b
chr1_+_55137943 0.55 ENSDART00000138070
ENSDART00000150510
ENSDART00000133472
ENSDART00000136378
myoglobin
chr6_-_35401282 0.55 ENSDART00000127612
regulator of G protein signaling 5a
chr9_-_100579 0.55 ENSDART00000006099
LIM and senescent cell antigen-like domains 2
chr21_+_13205859 0.54 ENSDART00000102253
spectrin alpha, non-erythrocytic 1
chr14_+_31657412 0.54 ENSDART00000105767
four and a half LIM domains 1a
chr23_+_25879320 0.54 ENSDART00000124963
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr6_-_15653494 0.53 ENSDART00000038133
tripartite motif containing 63a
chr2_+_55982940 0.52 ENSDART00000097753
ENSDART00000097751
nicotinamide riboside kinase 2
chr7_-_35708450 0.52 ENSDART00000193886
iroquois homeobox 5a
chr23_+_19790962 0.51 ENSDART00000142228
filamin A, alpha (actin binding protein 280)
chr18_-_6634424 0.51 ENSDART00000062423
ENSDART00000179955
troponin I, skeletal, slow c
chr20_+_46040666 0.50 ENSDART00000060744
si:dkey-7c18.24
chr18_+_5454341 0.50 ENSDART00000192649
DTW domain containing 1
chr5_+_1911814 0.49 ENSDART00000172233
si:ch73-55i23.1
chr3_-_34095221 0.49 ENSDART00000164235
ENSDART00000151377
immunoglobulin heavy variable 1-4
immunoglobulin heavy variable 5-4
chr18_+_2228737 0.49 ENSDART00000165301
RAB27A, member RAS oncogene family
chr22_-_10541712 0.49 ENSDART00000013933
si:dkey-42i9.4
chr5_-_26118855 0.48 ENSDART00000009028
elastase 3 like
chr22_-_651719 0.48 ENSDART00000148692
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a
chr22_-_57177 0.48 ENSDART00000163959

chr11_-_18705303 0.47 ENSDART00000059732
inhibitor of DNA binding 1
chr12_-_26064105 0.45 ENSDART00000168825
LIM domain binding 3b
chr5_-_36837846 0.45 ENSDART00000032481
creatine kinase, muscle a
chr18_-_49020066 0.45 ENSDART00000174394

chr17_+_1323699 0.45 ENSDART00000172540
adenylosuccinate synthase like 1
chr3_-_50865079 0.44 ENSDART00000164295
peripheral myelin protein 22a
chr7_+_65586624 0.44 ENSDART00000184344
microtubule associated monooxygenase, calponin and LIM domain containing 2a
chr8_+_21376290 0.44 ENSDART00000136765
elastase 2
chr17_-_681142 0.44 ENSDART00000165583
heme-binding protein soul3
chr3_-_30685401 0.44 ENSDART00000151097
si:ch211-51c14.1
chr7_-_44963154 0.43 ENSDART00000073735
Ras-related associated with diabetes
chr24_-_9300160 0.43 ENSDART00000152378
TGFB-induced factor homeobox 1
chr17_+_26657896 0.43 ENSDART00000152037
tetratricopeptide repeat domain 7B
chr19_-_5372572 0.43 ENSDART00000151326
keratin 17
chr7_-_48263516 0.42 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
RNA binding protein with multiple splicing 2b
chr16_+_26012569 0.42 ENSDART00000148846
protease, serine, 59, tandem duplicate 1
chr13_+_23157053 0.42 ENSDART00000162359
sorbin and SH3 domain containing 1
chr8_-_4586696 0.42 ENSDART00000143511
ENSDART00000134324
glycoprotein Ib (platelet), beta polypeptide
chr4_-_14915268 0.42 ENSDART00000067040
si:dkey-180p18.9
chr6_-_21189295 0.42 ENSDART00000137136
obscurin-like 1a
chr9_-_98982 0.42 ENSDART00000147882
LIM and senescent cell antigen-like domains 2
chr4_-_20181964 0.41 ENSDART00000022539
fibrinogen-like 2a
chr1_-_47431453 0.41 ENSDART00000101104
gap junction protein, alpha 5b
chr1_-_156375 0.41 ENSDART00000160221
PCI domain containing 2
chr20_+_23501535 0.40 ENSDART00000177922
ENSDART00000058532
palladin, cytoskeletal associated protein
chr3_+_59935606 0.40 ENSDART00000154157
Rho GDP dissociation inhibitor (GDI) alpha
chr7_+_35229805 0.40 ENSDART00000173911
tubulin polymerization-promoting protein family member 3
chr22_-_27115241 0.40 ENSDART00000019442
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr1_+_38142354 0.40 ENSDART00000179352
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr11_+_24313931 0.40 ENSDART00000017599
ENSDART00000166045
RAS (RAD and GEM)-like GTP-binding 1
chr11_+_37096520 0.40 ENSDART00000181503
caspase recruitment domain family, member 19
chr17_+_38573471 0.39 ENSDART00000040627
spectrin, beta, erythrocytic
chr2_-_21352101 0.39 ENSDART00000057021
hedgehog acyltransferase like, a
chr11_-_28050559 0.39 ENSDART00000136859
endothelin converting enzyme 1
chr2_+_55982300 0.38 ENSDART00000183903
nicotinamide riboside kinase 2
chr25_-_3867990 0.38 ENSDART00000075663
calcium release activated channel regulator 2B
chr14_-_25956804 0.38 ENSDART00000135627
ENSDART00000146022
ENSDART00000039660
secreted protein, acidic, cysteine-rich (osteonectin)
chr18_+_29145681 0.38 ENSDART00000089031
ENSDART00000193336
PTPRF interacting protein, binding protein 2a (liprin beta 2)
chr24_+_39108243 0.37 ENSDART00000156353
MSS51 mitochondrial translational activator
chr23_+_25708787 0.37 ENSDART00000060059
RNA binding motif, single stranded interacting protein 2b
chr1_-_38816685 0.37 ENSDART00000075230
ankyrin repeat and SOCS box containing 5b
chr12_-_28570989 0.37 ENSDART00000008010
pyruvate dehydrogenase kinase, isozyme 2a
chr14_+_146857 0.37 ENSDART00000122521

chr17_-_25382367 0.37 ENSDART00000162306
ENSDART00000165282
LCK proto-oncogene, Src family tyrosine kinase
chr13_+_52061034 0.37 ENSDART00000170383

chr1_+_1915967 0.37 ENSDART00000131463
si:ch211-132g1.1
chr11_+_24314148 0.36 ENSDART00000171491
RAS (RAD and GEM)-like GTP-binding 1
chr13_-_349952 0.36 ENSDART00000133731
ENSDART00000140326
ENSDART00000189389
ENSDART00000185865
ENSDART00000109634
ENSDART00000147058
ENSDART00000142695
si:ch1073-291c23.2
chr18_+_26899316 0.36 ENSDART00000050230
tetraspanin 3a
chr6_-_39051319 0.36 ENSDART00000155093
tensin 2b
chr5_-_26566435 0.35 ENSDART00000146070
ARVCF, delta catenin family member b
chr7_-_41858513 0.35 ENSDART00000109918
myosin light chain kinase 3
chr14_-_17563773 0.35 ENSDART00000082667
fibroblast growth factor receptor like 1a
chr5_-_22052852 0.35 ENSDART00000002938
myotubularin related protein 8
chr16_-_31469065 0.35 ENSDART00000182397
si:ch211-251p5.5
chr7_+_22767678 0.35 ENSDART00000137203
plac8 onzin related protein 6
chr8_-_18582922 0.35 ENSDART00000123917
transmembrane protein 47
chr21_+_28747069 0.35 ENSDART00000014058
zgc:100829
chr21_+_28747236 0.34 ENSDART00000137874
zgc:100829
chr23_+_18722715 0.34 ENSDART00000137438
myosin, heavy chain 7B, cardiac muscle, beta b
chr19_+_46113828 0.34 ENSDART00000159331
ENSDART00000161826
RNA binding motif protein 24a
chr23_+_18722915 0.33 ENSDART00000025057
myosin, heavy chain 7B, cardiac muscle, beta b
chr24_+_8736497 0.33 ENSDART00000181904
transmembrane protein 14Ca
chr17_+_32360673 0.33 ENSDART00000155519
si:ch211-139d20.3
chr10_-_35410518 0.32 ENSDART00000048430
gamma-aminobutyric acid (GABA) A receptor, rho 3a
chr23_+_19213472 0.32 ENSDART00000185985
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2b
chr18_-_14337450 0.32 ENSDART00000061435
heat shock factor binding protein 1b
chr8_-_7093507 0.32 ENSDART00000045669
si:dkey-222n6.2
chr2_+_45643122 0.32 ENSDART00000138179
fibronectin type III domain containing 7, related sequence 4
chr20_-_26551210 0.32 ENSDART00000077715
si:dkey-25e12.3
chr21_+_28749720 0.31 ENSDART00000145178
zgc:100829
chr1_-_59567685 0.31 ENSDART00000159144
ENSDART00000182913
zmp:0000001082
chr19_+_31904836 0.31 ENSDART00000162297
ENSDART00000088340
ENSDART00000151280
ENSDART00000151218
tumor protein D52
chr3_+_13559199 0.31 ENSDART00000166547
si:ch73-106n3.1
chr18_-_26101800 0.31 ENSDART00000004692
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr7_-_73843720 0.31 ENSDART00000111622
caspase activity and apoptosis inhibitor 1
chr22_+_7439186 0.31 ENSDART00000190667
zgc:92041
chr13_-_37615029 0.31 ENSDART00000111199
si:dkey-188i13.6
chr10_-_35220285 0.30 ENSDART00000180439
yippee-like 2a
chr5_+_64900223 0.30 ENSDART00000191677
prostaglandin-endoperoxide synthase 1
chr16_+_44768361 0.30 ENSDART00000036302
uroplakin 1a
chr21_-_20840714 0.30 ENSDART00000144861
ENSDART00000139430
complement component 6
chr12_+_5708400 0.30 ENSDART00000017191
distal-less homeobox 3b
chr13_+_25200105 0.30 ENSDART00000039640
adaptor-related protein complex 3, mu 1 subunit
chr12_-_25380028 0.30 ENSDART00000142674
zinc finger protein 36, C3H type-like 2
chr11_-_544187 0.30 ENSDART00000173161

chr13_+_32148338 0.29 ENSDART00000188591
odd-skipped related transciption factor 1
chr25_-_20258508 0.29 ENSDART00000133860
ENSDART00000006840
ENSDART00000173434
dynamin 1-like
chr13_+_228045 0.29 ENSDART00000161091
zgc:64201
chr14_-_15699528 0.29 ENSDART00000161123
neuralized E3 ubiquitin protein ligase 1B
chr19_+_24488403 0.29 ENSDART00000052421
thioredoxin interacting protein a
chr3_+_27713610 0.29 ENSDART00000019004
Rho GDP dissociation inhibitor (GDI) gamma
chr6_+_2097690 0.29 ENSDART00000193770
transglutaminase 2b
chr3_-_34060153 0.29 ENSDART00000151610
immunoglobulin heavy variable 1-1
chr21_+_30950097 0.29 ENSDART00000187572
ras homolog family member Gb
chr21_-_4250682 0.29 ENSDART00000099389
DNL-type zinc finger
chr9_-_105135 0.28 ENSDART00000180126

chr3_-_34069637 0.28 ENSDART00000151588
immunoglobulin heavy variable 9-1
chr21_-_45882643 0.28 ENSDART00000168703
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr13_+_32144370 0.28 ENSDART00000020270
odd-skipped related transciption factor 1
chr11_+_13166750 0.28 ENSDART00000169961
MOB kinase activator 3C
chr23_-_30041065 0.28 ENSDART00000131209
ENSDART00000127192
coiled-coil domain containing 187
chr11_-_30636163 0.28 ENSDART00000140516
zgc:153665
chr23_+_19814371 0.28 ENSDART00000182897
emerin (Emery-Dreifuss muscular dystrophy)
chr6_-_10912424 0.28 ENSDART00000036456
cytochrome c, somatic b
chr3_-_180860 0.28 ENSDART00000059956
ENSDART00000192506
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr13_+_42124566 0.28 ENSDART00000074707
CDC42 effector protein (Rho GTPase binding) 3
chr19_-_43639331 0.28 ENSDART00000138009
ENSDART00000086138
family with sequence similarity 83, member Hb
chr21_+_11776328 0.28 ENSDART00000134469
ENSDART00000081646
glutaredoxin (thioltransferase)
chr8_-_44298964 0.27 ENSDART00000098520
frizzled class receptor 10
chr12_-_48168135 0.27 ENSDART00000186624
phosphatase domain containing, paladin 1a
chr15_-_29387446 0.27 ENSDART00000145976
ENSDART00000035096
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr10_-_342564 0.27 ENSDART00000157633
vasodilator stimulated phosphoprotein a
chr23_-_31512496 0.27 ENSDART00000158755
ENSDART00000143425
EYA transcriptional coactivator and phosphatase 4
chr14_+_38786298 0.27 ENSDART00000164440
si:ch211-195b11.3
chr11_-_43104475 0.27 ENSDART00000125368
acylphosphatase 2, muscle type
chr25_+_16601839 0.27 ENSDART00000008986
ATPase H+ transporting V1 subunit E1a
chr5_-_26466169 0.27 ENSDART00000144035
ARVCF, delta catenin family member b
chr3_-_32590164 0.27 ENSDART00000151151
tetraspanin 4b
chr2_-_44255537 0.27 ENSDART00000011188
ENSDART00000093298
ATPase Na+/K+ transporting subunit alpha 2
chr3_-_4574372 0.27 ENSDART00000172023
ENSDART00000168724
finTRIM family, member 50
chr15_-_4528326 0.27 ENSDART00000158122
ENSDART00000155619
ENSDART00000128602
transcription factor Dp-2
chr14_+_30340251 0.27 ENSDART00000148448
microtubule associated tumor suppressor 1a
chr2_+_22851832 0.27 ENSDART00000145944
angiomotin like 2b
chr8_-_30242706 0.26 ENSDART00000139864
ENSDART00000143809
zgc:162939
chr5_+_37854685 0.26 ENSDART00000051222
ENSDART00000185283
preproinsulin
chr7_+_35229645 0.26 ENSDART00000144327
tubulin polymerization-promoting protein family member 3
chr9_-_48281941 0.26 ENSDART00000099787
kelch-like family member 41a
chr20_+_46385907 0.26 ENSDART00000060710
adhesion G protein-coupled receptor G11
chr6_-_48082525 0.26 ENSDART00000192049
solute carrier family 2 (facilitated glucose transporter), member 1b
chr20_+_2039518 0.26 ENSDART00000043157

chr5_+_24287927 0.26 ENSDART00000143563
zinc finger, DHHC-type containing 23a
chr9_+_30585552 0.26 ENSDART00000160590
ENSDART00000189815
ENSDART00000143766
TBC1 domain family, member 4
chr14_-_36412473 0.26 ENSDART00000128244
ENSDART00000138376
ankyrin repeat and SOCS box containing 5a
chr21_+_5974590 0.26 ENSDART00000098499
deoxycytidine kinase
chr3_-_34089310 0.26 ENSDART00000151774
immunoglobulin heavy variable 5-5
chr18_+_35842933 0.25 ENSDART00000151587
ENSDART00000131121
protein phosphatase 1, regulatory subunit 13 like
chr4_-_16412084 0.25 ENSDART00000188460
decorin
chr17_+_132555 0.25 ENSDART00000158159
zgc:77287
chr6_-_10788065 0.25 ENSDART00000190968
WAS/WASL interacting protein family, member 1b
chr17_+_16090436 0.25 ENSDART00000136059
ENSDART00000138734
zinc finger protein 395a
chr24_-_14711597 0.25 ENSDART00000131830
junctophilin 1a
chr9_-_23990416 0.25 ENSDART00000113176
collagen, type VI, alpha 3
chr16_+_3004422 0.25 ENSDART00000189969

chr16_-_21810668 0.25 ENSDART00000156575
diverse immunoglobulin domain-containing protein 3.3
chr9_+_40874194 0.25 ENSDART00000141548
3-hydroxyisobutyryl-CoA hydrolase
chr16_-_7239457 0.24 ENSDART00000148992
ENSDART00000149260
5'-nucleotidase, cytosolic IIIA
chr1_-_17587552 0.24 ENSDART00000039917
acyl-CoA synthetase long chain family member 1a
chr20_-_37831849 0.24 ENSDART00000188483
ENSDART00000153005
ENSDART00000142364
si:ch211-147d7.5
chr13_-_15994419 0.24 ENSDART00000079724
ENSDART00000042377
ENSDART00000046079
ENSDART00000050481
ENSDART00000016430
IKAROS family zinc finger 1 (Ikaros)
chr15_-_23814330 0.24 ENSDART00000153843
si:ch211-167j9.5
chr18_+_25752592 0.24 ENSDART00000111767
si:ch211-39k3.2
chr5_-_14521500 0.24 ENSDART00000176565
si:ch211-244o22.2
chr8_+_50946379 0.24 ENSDART00000139649
beta-2-microglobulin, like
chr2_+_16191852 0.24 ENSDART00000152046
SH3-domain GRB2-like endophilin B1b
chr17_-_45370200 0.24 ENSDART00000186208
zinc finger protein 106a
chr23_-_18130264 0.24 ENSDART00000016976
nuclear casein kinase and cyclin-dependent kinase substrate 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of tcf3a+tcf3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.3 0.8 GO:0043388 cytidine to uridine editing(GO:0016554) positive regulation of DNA binding(GO:0043388)
0.3 1.3 GO:0003210 cardiac atrium formation(GO:0003210)
0.2 1.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 1.3 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.2 0.6 GO:0048389 intermediate mesoderm development(GO:0048389)
0.2 0.9 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.5 GO:0060254 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.2 0.5 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.2 0.6 GO:0009098 leucine biosynthetic process(GO:0009098)
0.1 1.0 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.3 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.3 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.8 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.3 GO:0065001 specification of axis polarity(GO:0065001)
0.1 0.4 GO:0051148 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.1 0.2 GO:0009595 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.1 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.1 0.3 GO:0030858 positive regulation of epithelial cell differentiation(GO:0030858) negative regulation of behavior(GO:0048521) negative regulation of feeding behavior(GO:2000252)
0.1 0.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 1.0 GO:0048769 sarcomerogenesis(GO:0048769)
0.1 0.2 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.2 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134) toll-like receptor 3 signaling pathway(GO:0034138)
0.1 0.2 GO:0098801 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093) regulation of renal system process(GO:0098801)
0.1 0.2 GO:1901207 regulation of heart looping(GO:1901207)
0.1 0.2 GO:0003156 regulation of organ formation(GO:0003156)
0.1 1.2 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.1 0.2 GO:0051037 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1 0.5 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.1 0.2 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.3 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.3 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.0 0.2 GO:0060406 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.0 0.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.0 0.5 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711) chiasma assembly(GO:0051026)
0.0 0.2 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.5 GO:2000403 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.2 GO:0070254 mucus secretion(GO:0070254)
0.0 0.5 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:1903573 negative regulation of response to endoplasmic reticulum stress(GO:1903573)
0.0 2.3 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.1 GO:1990120 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.2 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.2 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.1 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.7 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.3 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.0 0.2 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.3 GO:0035912 establishment of cell polarity involved in ameboidal cell migration(GO:0003365) aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0033292 T-tubule organization(GO:0033292)
0.0 0.2 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:1900157 negative regulation of chondrocyte differentiation(GO:0032331) negative regulation of cartilage development(GO:0061037) negative regulation of chondrocyte development(GO:0061182) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158) negative regulation of bone development(GO:1903011)
0.0 0.1 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.1 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.0 0.6 GO:0015671 oxygen transport(GO:0015671)
0.0 0.7 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:1903334 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.0 0.1 GO:0071380 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.7 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.2 GO:1990402 embryonic liver development(GO:1990402)
0.0 0.1 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.0 0.3 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:0070084 protein initiator methionine removal(GO:0070084)
0.0 0.4 GO:0030534 adult behavior(GO:0030534)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.4 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0045582 positive regulation of T cell differentiation(GO:0045582)
0.0 0.2 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.1 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.5 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.2 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.1 GO:0043300 mast cell activation involved in immune response(GO:0002279) mast cell mediated immunity(GO:0002448) regulation of mast cell activation(GO:0033003) regulation of mast cell activation involved in immune response(GO:0033006) leukocyte degranulation(GO:0043299) regulation of leukocyte degranulation(GO:0043300) mast cell degranulation(GO:0043303) regulation of mast cell degranulation(GO:0043304)
0.0 0.2 GO:1903039 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.2 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.3 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0051103 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.0 0.0 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.8 GO:0014029 neural crest formation(GO:0014029)
0.0 1.2 GO:0051693 actin filament capping(GO:0051693)
0.0 0.2 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.2 GO:1901998 toxin transport(GO:1901998)
0.0 0.1 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.0 0.2 GO:0030104 water homeostasis(GO:0030104)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 0.2 GO:0019320 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) hexose catabolic process(GO:0019320) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.4 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.2 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.0 0.1 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.6 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.3 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.0 0.2 GO:0021794 thalamus development(GO:0021794)
0.0 0.5 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 1.7 GO:0031101 fin regeneration(GO:0031101)
0.0 0.1 GO:0086002 cardiac muscle cell action potential involved in contraction(GO:0086002)
0.0 0.1 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.1 GO:0032370 positive regulation of lipid transport(GO:0032370)
0.0 0.0 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.0 0.1 GO:0045988 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) positive regulation of striated muscle contraction(GO:0045989) relaxation of skeletal muscle(GO:0090076)
0.0 0.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0003207 cardiac chamber formation(GO:0003207)
0.0 0.1 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.0 GO:0021571 rhombomere 5 development(GO:0021571) rhombomere 6 development(GO:0021572)
0.0 0.2 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.3 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.2 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.7 GO:0050879 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.0 0.1 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.5 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.0 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.7 GO:0072676 lymphocyte migration(GO:0072676)
0.0 0.4 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.2 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.0 0.1 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.0 0.4 GO:0048794 swim bladder development(GO:0048794)
0.0 0.1 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.5 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.1 GO:0032447 protein urmylation(GO:0032447)
0.0 0.1 GO:0071688 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.1 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124) caudal fin morphogenesis(GO:0035143)
0.0 0.1 GO:0032418 lysosome localization(GO:0032418)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.5 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0021986 habenula development(GO:0021986)
0.0 0.2 GO:0061055 myotome development(GO:0061055)
0.0 0.0 GO:0003342 proepicardium development(GO:0003342) septum transversum development(GO:0003343)
0.0 0.0 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.0 0.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.0 0.3 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.0 GO:1903792 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.0 0.5 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 1.1 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.1 GO:0051122 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.0 GO:0060036 notochord cell vacuolation(GO:0060036)
0.0 0.0 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.2 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.1 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0008592 regulation of Toll signaling pathway(GO:0008592)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0033268 node of Ranvier(GO:0033268)
0.1 1.4 GO:0045095 keratin filament(GO:0045095)
0.1 0.5 GO:0070390 transcription export complex 2(GO:0070390)
0.1 1.9 GO:0031430 M band(GO:0031430)
0.1 0.4 GO:0008091 spectrin(GO:0008091)
0.1 0.2 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 1.5 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0008352 katanin complex(GO:0008352)
0.0 0.1 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.3 GO:0070449 elongin complex(GO:0070449)
0.0 0.1 GO:0072380 TRC complex(GO:0072380)
0.0 2.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0031672 A band(GO:0031672)
0.0 0.1 GO:0097541 axonemal basal plate(GO:0097541)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 2.2 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.9 GO:0030055 cell-substrate junction(GO:0030055)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.6 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.0 GO:1990879 CST complex(GO:1990879)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.3 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.0 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.0 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 0.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.6 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.6 GO:0071253 connexin binding(GO:0071253)
0.1 0.8 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.9 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 1.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.3 GO:1990825 mRNA CDS binding(GO:1990715) sequence-specific mRNA binding(GO:1990825)
0.1 0.3 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.1 0.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.5 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 0.9 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.4 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.3 GO:0031005 filamin binding(GO:0031005)
0.1 0.3 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.1 0.2 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.2 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.2 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 0.2 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 2.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0004557 alpha-galactosidase activity(GO:0004557)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0004473 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.5 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.2 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.6 GO:0005344 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.5 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.3 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.2 GO:0070095 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:1990931 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.0 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.0 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.0 GO:0031704 apelin receptor binding(GO:0031704)
0.0 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.0 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 2.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 PID FOXO PATHWAY FoxO family signaling
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.9 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.5 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.1 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.3 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase