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PRJNA207719: Tissue specific transcriptome profiling

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Results for tcf21

Z-value: 1.63

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Transcription factors associated with tcf21

Gene Symbol Gene ID Gene Info
tcf21
ENSDARG00000036869 transcription factor 21
tcf21
ENSDARG00000111209 transcription factor 21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tcf21dr11_v1_chr23_-_31555696_31555696-0.266.8e-01Click!

Activity profile of tcf21 motif

Sorted Z-values of tcf21 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_34794829 1.78 ENSDART00000009698
ENSDART00000075089
ENSDART00000173456
esrp2
epithelial splicing regulatory protein 2
chr3_+_1055588 1.72 ENSDART00000143220
zgc:153921
zgc:153921
chr5_+_28830643 1.57 ENSDART00000051448
serpina7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr6_+_112579 1.50 ENSDART00000034505
ap1m2
adaptor-related protein complex 1, mu 2 subunit
chr11_-_5865744 1.39 ENSDART00000104360
gamt
guanidinoacetate N-methyltransferase
chr5_+_28849155 1.38 ENSDART00000079090
zgc:174259
zgc:174259
chr5_+_28858345 1.12 ENSDART00000111180
si:ch211-186e20.2
si:ch211-186e20.2
chr7_+_6652967 0.96 ENSDART00000102681
pnp5a
purine nucleoside phosphorylase 5a
chr9_-_35633827 0.96 ENSDART00000077745
zp2l1
zona pellucida glycoprotein 2, like 1
chr19_+_43119014 0.89 ENSDART00000023156
eef1a1l1
eukaryotic translation elongation factor 1 alpha 1, like 1
chr7_+_10610791 0.87 ENSDART00000166064
fah
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr3_-_21094437 0.85 ENSDART00000153739
ENSDART00000109790
nlk1
nemo-like kinase, type 1
chr20_-_26551210 0.83 ENSDART00000077715
si:dkey-25e12.3
si:dkey-25e12.3
chr7_+_2455344 0.80 ENSDART00000172942
si:dkey-125e8.4
si:dkey-125e8.4
chr6_-_8360918 0.80 ENSDART00000004716
acp5a
acid phosphatase 5a, tartrate resistant
chr2_+_4208323 0.80 ENSDART00000167906
gata6
GATA binding protein 6
chr16_+_23972126 0.79 ENSDART00000132742
ENSDART00000145330
apoc1
apolipoprotein C-I
chr15_-_945804 0.79 ENSDART00000063257
alox5b.1
arachidonate 5-lipoxygenase b, tandem duplicate 1
chr5_+_28857969 0.78 ENSDART00000149850
si:ch211-186e20.2
si:ch211-186e20.2
chr20_+_42668875 0.77 ENSDART00000048890
slc22a2
solute carrier family 22 (organic cation transporter), member 2
chr10_-_25217347 0.76 ENSDART00000036906
kpna7
karyopherin alpha 7 (importin alpha 8)
chr16_-_31686602 0.74 ENSDART00000170357
c1s
complement component 1, s subcomponent
chr7_-_24364536 0.73 ENSDART00000064789
txn
thioredoxin
chr2_-_17114852 0.73 ENSDART00000006549
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr15_-_39969988 0.71 ENSDART00000146054
rps5
ribosomal protein S5
chr5_+_28848870 0.68 ENSDART00000149563
zgc:174259
zgc:174259
chr10_+_31809226 0.67 ENSDART00000087898
foxo1b
forkhead box O1 b
chr21_-_20929575 0.66 ENSDART00000163889
c6
complement component 6
chr24_+_22056386 0.65 ENSDART00000132390
ankrd33ba
ankyrin repeat domain 33ba
chr12_+_20693743 0.64 ENSDART00000153023
ENSDART00000153370
st6galnac1.2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 2
chr19_+_43119698 0.64 ENSDART00000167847
ENSDART00000186962
ENSDART00000187305
eef1a1l1
eukaryotic translation elongation factor 1 alpha 1, like 1
chr8_-_25247284 0.64 ENSDART00000132697
gnat2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr15_+_46344655 0.64 ENSDART00000155893
si:ch1073-340i21.2
si:ch1073-340i21.2
chr5_+_28830388 0.63 ENSDART00000149150
serpina7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr5_-_65000312 0.63 ENSDART00000192893
ANXA1 (1 of many)
zgc:110283
chr25_-_7650335 0.62 ENSDART00000089034
myo5ab
myosin VAb
chr8_+_45334255 0.62 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
pabpc1l
poly(A) binding protein, cytoplasmic 1-like
chr14_-_34605607 0.61 ENSDART00000191608
afap1l1a
actin filament associated protein 1-like 1a
chr20_-_35578435 0.60 ENSDART00000142444
adgrf6
adhesion G protein-coupled receptor F6
chr11_-_183328 0.59 ENSDART00000168562
avil
advillin
chr8_+_39724138 0.59 ENSDART00000009323
pla2g1b
phospholipase A2, group IB (pancreas)
chr8_-_19280856 0.59 ENSDART00000100473
zgc:77486
zgc:77486
chr10_+_35491216 0.59 ENSDART00000109705
phldb2a
pleckstrin homology-like domain, family B, member 2a
chr12_+_30360184 0.58 ENSDART00000190718
si:ch211-225b10.3
si:ch211-225b10.3
chr1_+_52560549 0.58 ENSDART00000167514
abca1a
ATP-binding cassette, sub-family A (ABC1), member 1A
chr23_-_18057270 0.57 ENSDART00000173385
zgc:92287
zgc:92287
chr1_+_33390286 0.57 ENSDART00000139004
dhrsx
dehydrogenase/reductase (SDR family) X-linked
chr2_-_44344321 0.57 ENSDART00000084174
lig1
ligase I, DNA, ATP-dependent
chr9_-_3519253 0.57 ENSDART00000169586
dcaf17
ddb1 and cul4 associated factor 17
chr23_+_29908348 0.57 ENSDART00000186622
ENSDART00000150174
si:ch73-236e11.2
si:ch73-236e11.2
chr6_-_54348568 0.55 ENSDART00000156501
zgc:101577
zgc:101577
chr19_+_2877079 0.55 ENSDART00000160847
hgh1
HGH1 homolog (S. cerevisiae)
chr22_-_16154771 0.55 ENSDART00000009464
slc30a7
solute carrier family 30 (zinc transporter), member 7
chr5_+_25762271 0.54 ENSDART00000181323
tmem2
transmembrane protein 2
chr7_-_8010102 0.54 ENSDART00000190305
si:cabz01030277.1
si:cabz01030277.1
chr2_-_17115256 0.53 ENSDART00000190488
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr5_-_64900552 0.53 ENSDART00000073963
si:ch211-236k19.2
si:ch211-236k19.2
chr10_+_29849977 0.53 ENSDART00000180242
hspa8
heat shock protein 8
chr17_+_8323348 0.52 ENSDART00000169900
cdc42bpaa
CDC42 binding protein kinase alpha (DMPK-like) a
chr18_+_34861568 0.52 ENSDART00000192825
LO018333.1

chr17_-_14836320 0.51 ENSDART00000157051
nid2a
nidogen 2a (osteonidogen)
chr10_-_44560165 0.51 ENSDART00000181217
ENSDART00000076084
npm2b
nucleophosmin/nucleoplasmin, 2b
chr7_+_49664174 0.51 ENSDART00000137059
ENSDART00000131210
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr10_+_29850330 0.51 ENSDART00000168898
hspa8
heat shock protein 8
chr14_-_34605804 0.50 ENSDART00000144547
afap1l1a
actin filament associated protein 1-like 1a
chr5_+_1911814 0.50 ENSDART00000172233
si:ch73-55i23.1
si:ch73-55i23.1
chr10_+_26667475 0.49 ENSDART00000133281
ENSDART00000147013
si:ch73-52f15.5
si:ch73-52f15.5
chr24_+_37709191 0.49 ENSDART00000066558
decr2
2,4-dienoyl CoA reductase 2, peroxisomal
chr21_-_39253647 0.48 ENSDART00000133034
tusc5b
tumor suppressor candidate 5b
chr19_+_7636941 0.48 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cgnb
cingulin b
chr5_+_13549603 0.48 ENSDART00000171270
ckap2l
cytoskeleton associated protein 2-like
chr10_+_24445698 0.48 ENSDART00000146370
slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr9_+_21146862 0.48 ENSDART00000136365
hao2
hydroxyacid oxidase 2 (long chain)
chr25_+_3326885 0.48 ENSDART00000104866
ldhbb
lactate dehydrogenase Bb
chr19_+_31541607 0.47 ENSDART00000181604
gmnn
geminin, DNA replication inhibitor
chr1_-_39895859 0.46 ENSDART00000135791
ENSDART00000035739
tmem134
transmembrane protein 134
chr3_-_14571514 0.45 ENSDART00000137197
swsap1
SWIM-type zinc finger 7 associated protein 1
chr8_-_27687095 0.45 ENSDART00000086946
mov10b.1
Moloney leukemia virus 10b, tandem duplicate 1
chr3_-_16537441 0.45 ENSDART00000080749
ENSDART00000133824
eps8l1
eps8-like1
chr11_+_21096339 0.45 ENSDART00000124574
il19l
interleukin 19 like
chr7_-_6357952 0.45 ENSDART00000173197
zgc:165555
zgc:165555
chr24_-_25166416 0.45 ENSDART00000111552
ENSDART00000169495
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr12_+_30360579 0.44 ENSDART00000152900
si:ch211-225b10.3
si:ch211-225b10.3
chr17_+_8799451 0.44 ENSDART00000189814
ENSDART00000191577
tonsl
tonsoku-like, DNA repair protein
chr5_-_29152457 0.44 ENSDART00000078469
noxa1
NADPH oxidase activator 1
chr13_+_40770628 0.43 ENSDART00000085846
nkx1.2la
NK1 transcription factor related 2-like,a
chr24_-_25166720 0.43 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr9_-_49531762 0.43 ENSDART00000121875
xirp2b
xin actin binding repeat containing 2b
chr23_+_1730663 0.42 ENSDART00000149545
tgm1
transglutaminase 1, K polypeptide
chr3_+_4266289 0.42 ENSDART00000101636
si:dkey-73p2.1
si:dkey-73p2.1
chr17_+_53156530 0.41 ENSDART00000126277
ENSDART00000156774
dph6
diphthamine biosynthesis 6
chr11_-_35171162 0.41 ENSDART00000017393
traip
TRAF-interacting protein
chr6_+_56141852 0.41 ENSDART00000149665
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr5_-_24238733 0.40 ENSDART00000138170
plscr3a
phospholipid scramblase 3a
chr19_+_9666961 0.40 ENSDART00000104596
ENSDART00000132124
si:dkey-14o18.6
si:dkey-14o18.6
chr7_+_30051880 0.40 ENSDART00000075609
pstpip1b
proline-serine-threonine phosphatase interacting protein 1b
chr2_-_31833347 0.39 ENSDART00000109460
nol7
nucleolar protein 7
chr12_-_44196222 0.39 ENSDART00000171730
si:ch73-329n5.1
si:ch73-329n5.1
chr5_-_57480660 0.39 ENSDART00000147875
ENSDART00000142776
si:ch211-202f5.2
si:ch211-202f5.2
chr22_+_19264181 0.39 ENSDART00000192750
ENSDART00000137591
ENSDART00000136197
si:dkey-78l4.5
si:dkey-21e2.11
si:dkey-78l4.5
si:dkey-21e2.11
chr22_+_8701238 0.39 ENSDART00000106092
zmp:0000000652
zmp:0000000652
chr1_-_52498146 0.39 ENSDART00000122217
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr18_+_3052408 0.38 ENSDART00000181563
kctd14
potassium channel tetramerization domain containing 14
chr15_-_18197008 0.37 ENSDART00000147632
si:ch211-247l8.8
si:ch211-247l8.8
chr15_+_20403084 0.37 ENSDART00000141388
ENSDART00000152734
cox7a1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr7_+_4971938 0.37 ENSDART00000172889
ENSDART00000145389
si:dkey-81n2.2
si:dkey-81n2.2
chr2_+_36620011 0.37 ENSDART00000177428
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr13_-_37619159 0.37 ENSDART00000186348
zgc:152791
zgc:152791
chr14_+_34952883 0.36 ENSDART00000182812
il12ba
interleukin 12Ba
chr5_+_50879545 0.36 ENSDART00000128402
nol6
nucleolar protein 6 (RNA-associated)
chr1_-_34450784 0.36 ENSDART00000140515
lmo7b
LIM domain 7b
chr2_+_32016256 0.35 ENSDART00000005143
mycb
MYC proto-oncogene, bHLH transcription factor b
chr15_+_32727848 0.35 ENSDART00000161361
postnb
periostin, osteoblast specific factor b
chr16_+_41135018 0.35 ENSDART00000139435
si:ch211-53m15.2
si:ch211-53m15.2
chr5_+_37068223 0.35 ENSDART00000164279
si:dkeyp-110c7.4
si:dkeyp-110c7.4
chr14_+_9287683 0.35 ENSDART00000122485
msnb
moesin b
chr22_-_10470663 0.34 ENSDART00000143352
omd
osteomodulin
chr18_+_33132266 0.34 ENSDART00000151623
si:ch211-229c8.14
si:ch211-229c8.14
chr13_-_24260609 0.34 ENSDART00000138747
urb2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr8_-_32805214 0.34 ENSDART00000131597
zgc:194839
zgc:194839
chr5_+_4366431 0.33 ENSDART00000168560
ENSDART00000149185
sat1a.2
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr13_+_24584401 0.33 ENSDART00000057599
fuom
fucose mutarotase
chr1_+_58137020 0.33 ENSDART00000180887
si:ch211-15j1.4
si:ch211-15j1.4
chr18_-_7948188 0.32 ENSDART00000091805
shank3a
SH3 and multiple ankyrin repeat domains 3a
chr7_+_34231782 0.32 ENSDART00000173547
lctla
lactase-like a
chr7_+_30051488 0.32 ENSDART00000169410
pstpip1b
proline-serine-threonine phosphatase interacting protein 1b
chr16_-_42750295 0.32 ENSDART00000176570
slc4a7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr2_+_32016516 0.32 ENSDART00000135040
mycb
MYC proto-oncogene, bHLH transcription factor b
chr5_+_23630384 0.32 ENSDART00000013745
cx39.9
connexin 39.9
chr22_+_1049367 0.32 ENSDART00000065380
camk1ga
calcium/calmodulin-dependent protein kinase IGa
chr14_+_80685 0.32 ENSDART00000188443
stag3
stromal antigen 3
chr22_+_19230434 0.32 ENSDART00000132929
si:dkey-21e2.8
si:dkey-21e2.8
chr18_-_10995410 0.32 ENSDART00000136751
tspan33b
tetraspanin 33b
chr7_-_66864756 0.31 ENSDART00000184462
ENSDART00000189424
ampd3a
adenosine monophosphate deaminase 3a
chr6_+_25261297 0.31 ENSDART00000162824
ENSDART00000163490
ENSDART00000157790
ENSDART00000160978
ENSDART00000161545
ENSDART00000159978
kyat3
kynurenine aminotransferase 3
chr13_+_21601149 0.31 ENSDART00000179369
sh2d4ba
SH2 domain containing 4Ba
chr13_+_11876437 0.31 ENSDART00000179753
trim8a
tripartite motif containing 8a
chr1_+_56843411 0.30 ENSDART00000152312
si:ch211-152f2.1
si:ch211-152f2.1
chr8_+_24747865 0.30 ENSDART00000078656
slc16a4
solute carrier family 16, member 4
chr21_-_12749501 0.30 ENSDART00000179724
LO018011.1

chr1_+_58228542 0.30 ENSDART00000132423
si:dkey-222h21.9
si:dkey-222h21.9
chr22_-_906757 0.30 ENSDART00000193182
FP016205.1

chr3_-_12227359 0.30 ENSDART00000167356
tfap4
transcription factor AP-4 (activating enhancer binding protein 4)
chr20_+_18163355 0.30 ENSDART00000011287
aqp4
aquaporin 4
chr16_+_33144112 0.29 ENSDART00000183149
rhbdl2
rhomboid, veinlet-like 2 (Drosophila)
chr7_+_44715224 0.29 ENSDART00000184630
si:dkey-56m19.5
si:dkey-56m19.5
chr6_-_43007264 0.29 ENSDART00000124623
si:ch73-361p23.3
si:ch73-361p23.3
chr8_+_22404981 0.29 ENSDART00000185211
ENSDART00000099972
si:dkey-23c22.7
si:dkey-23c22.9
si:dkey-23c22.7
si:dkey-23c22.9
chr15_+_28096152 0.29 ENSDART00000100293
ENSDART00000140092
crybb1l3
crystallin, beta B1, like 3
chr7_+_1473929 0.29 ENSDART00000050687
lpcat4
lysophosphatidylcholine acyltransferase 4
chr16_-_36905789 0.29 ENSDART00000102212
tdp2a
tyrosyl-DNA phosphodiesterase 2a
chr23_-_18057851 0.29 ENSDART00000173075
ENSDART00000173230
ENSDART00000173135
ENSDART00000173431
ENSDART00000173068
ENSDART00000172987
zgc:92287
zgc:92287
chr11_+_44503774 0.28 ENSDART00000169295
ero1b
endoplasmic reticulum oxidoreductase beta
chr14_+_21905492 0.28 ENSDART00000054437
tbc1d10c
TBC1 domain family, member 10C
chr1_-_40911332 0.28 ENSDART00000027463
hmx4
H6 family homeobox 4
chr5_-_19400166 0.28 ENSDART00000008994
foxn4
forkhead box N4
chr6_+_58915889 0.28 ENSDART00000083628
ddit3
DNA-damage-inducible transcript 3
chr15_+_6459847 0.28 ENSDART00000157250
ENSDART00000065824
bace2
beta-site APP-cleaving enzyme 2
chr7_-_24046999 0.28 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr1_-_52497834 0.28 ENSDART00000136469
ENSDART00000004233
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr2_-_51741711 0.27 ENSDART00000171301
si:ch211-9d9.1
si:ch211-9d9.1
chr1_-_34450622 0.27 ENSDART00000083736
lmo7b
LIM domain 7b
chr3_-_34724879 0.27 ENSDART00000177021
thraa
thyroid hormone receptor alpha a
chr12_-_9294819 0.27 ENSDART00000003805
pth1rb
parathyroid hormone 1 receptor b
chr4_-_43374443 0.27 ENSDART00000191022
BX927253.3

chr11_-_35171768 0.27 ENSDART00000192896
traip
TRAF-interacting protein
chr12_+_2660733 0.26 ENSDART00000152235
irbpl
interphotoreceptor retinoid-binding protein like
chr18_+_2228737 0.26 ENSDART00000165301
rab27a
RAB27A, member RAS oncogene family
chr11_+_29975830 0.26 ENSDART00000148929
si:ch73-226l13.2
si:ch73-226l13.2
chr6_+_42475730 0.26 ENSDART00000150226
mst1ra
macrophage stimulating 1 receptor a
chr4_+_7508316 0.26 ENSDART00000170924
ENSDART00000170933
ENSDART00000164985
ENSDART00000167571
ENSDART00000158843
ENSDART00000158999
tnnt2e
troponin T2e, cardiac
chr9_+_3519191 0.26 ENSDART00000008606
mettl8
methyltransferase like 8
chr15_+_37973197 0.25 ENSDART00000156661
si:dkey-238d18.9
si:dkey-238d18.9
chr14_+_32837914 0.25 ENSDART00000158888
arr3b
arrestin 3b, retinal (X-arrestin)
chr3_+_14571813 0.25 ENSDART00000146728
ENSDART00000171731
znf653
zinc finger protein 653
chr16_-_22004402 0.24 ENSDART00000145100
ENSDART00000188217
ENSDART00000180083
si:dkey-71b5.7
si:dkey-71b5.7
chr8_+_22405477 0.24 ENSDART00000148267
si:dkey-23c22.7
si:dkey-23c22.7
chr2_+_44977889 0.24 ENSDART00000144024
alg3
asparagine-linked glycosylation 3 (alpha-1,3-mannosyltransferase)
chr19_-_10432134 0.24 ENSDART00000081440
il11b
interleukin 11b
chr4_+_76353418 0.24 ENSDART00000171289
si:ch73-158p21.2
si:ch73-158p21.2
chr6_-_39344259 0.23 ENSDART00000104074
zgc:158846
zgc:158846
chr9_-_12811936 0.23 ENSDART00000188490
myo10l3
myosin X-like 3
chr15_-_38009344 0.23 ENSDART00000157094
si:dkey-238d18.6
si:dkey-238d18.6
chr21_-_293146 0.23 ENSDART00000157781
plgrkt
plasminogen receptor, C-terminal lysine transmembrane protein
chr23_-_19831739 0.23 ENSDART00000125066
haus7
HAUS augmin-like complex, subunit 7
chr5_-_23729590 0.23 ENSDART00000014831
si:dkey-110k5.10
si:dkey-110k5.10
chr12_-_33859950 0.23 ENSDART00000131181
sema4gb
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Gb
chr5_+_64900223 0.22 ENSDART00000191677
ptgs1
prostaglandin-endoperoxide synthase 1
chr15_-_25365319 0.22 ENSDART00000152651
cluha
clustered mitochondria (cluA/CLU1) homolog a
chr2_+_17508323 0.22 ENSDART00000169703
pimr199
Pim proto-oncogene, serine/threonine kinase, related 199
chr10_+_1590604 0.22 ENSDART00000166646
ora5
olfactory receptor class A related 5
chr21_+_19418563 0.22 ENSDART00000181113
ENSDART00000080110
amacr
alpha-methylacyl-CoA racemase
chr10_-_20065149 0.21 ENSDART00000182603
BX323022.1

chr3_+_58379450 0.21 ENSDART00000155759
sdr42e2
short chain dehydrogenase/reductase family 42E, member 2
chr21_-_37435162 0.21 ENSDART00000133585
fam114a2
family with sequence similarity 114, member A2
chr19_+_23308419 0.21 ENSDART00000141558
irgf2
immunity-related GTPase family, f2
chr2_-_7131657 0.21 ENSDART00000175565
ENSDART00000092116
extl2
exostosin-like glycosyltransferase 2
chr4_-_76154252 0.21 ENSDART00000161269
BX957252.1

chr23_-_44470253 0.21 ENSDART00000176333
si:ch1073-228j22.2
si:ch1073-228j22.2
chr2_-_49997055 0.20 ENSDART00000140294
si:ch211-106n13.3
si:ch211-106n13.3

Network of associatons between targets according to the STRING database.

First level regulatory network of tcf21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.3 0.8 GO:0050995 negative regulation of lipid transport(GO:0032369) negative regulation of lipid catabolic process(GO:0050995)
0.3 0.8 GO:0015695 organic cation transport(GO:0015695)
0.2 1.0 GO:0048260 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.2 0.8 GO:0043011 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.1 0.6 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.1 0.9 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.4 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 1.3 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.1 0.6 GO:0006266 DNA ligation(GO:0006266) DNA ligation involved in DNA repair(GO:0051103)
0.1 0.3 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.6 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.1 0.7 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.1 0.5 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.3 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 0.6 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.2 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.1 0.6 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.8 GO:0045453 bone resorption(GO:0045453)
0.1 6.1 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.4 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.8 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.4 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.3 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.4 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.3 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.3 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.6 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.0 0.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.5 GO:2000403 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.0 0.6 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.3 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.4 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0070084 protein initiator methionine removal(GO:0070084)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.3 GO:0006833 water transport(GO:0006833)
0.0 0.4 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0015860 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.0 0.3 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.0 0.2 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.5 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 1.5 GO:0006414 translational elongation(GO:0006414)
0.0 0.3 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.6 GO:0019835 cytolysis(GO:0019835)
0.0 1.3 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.5 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.6 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.0 0.5 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.3 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.0 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.0 0.7 GO:0031638 zymogen activation(GO:0031638)
0.0 0.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.5 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.3 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.0 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.0 0.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0032545 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.1 0.4 GO:0043514 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.1 1.1 GO:0002102 podosome(GO:0002102)
0.1 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.8 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.1 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 1.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.0 1.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.3 GO:0005657 replication fork(GO:0005657)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0097519 DNA recombinase complex(GO:0097519)
0.0 0.5 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.0 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 0.5 GO:0043186 P granule(GO:0043186)
0.0 0.3 GO:0045178 basal part of cell(GO:0045178) basal cortex(GO:0045180)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.2 0.6 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2 0.9 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 0.5 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.1 0.6 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.8 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.1 0.3 GO:0042806 fucose binding(GO:0042806)
0.1 1.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.8 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 0.3 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.4 GO:0019972 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.1 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 1.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.8 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.1 0.3 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.8 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.1 0.7 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 1.1 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.5 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 5.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 1.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0070738 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 0.1 GO:0015217 ATP:ADP antiporter activity(GO:0005471) ADP transmembrane transporter activity(GO:0015217)
0.0 0.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.2 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.3 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.5 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 1.1 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.6 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.7 GO:0019843 rRNA binding(GO:0019843)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0005501 retinoid binding(GO:0005501) isoprenoid binding(GO:0019840)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.8 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 2.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 0.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.6 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.2 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 1.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives