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PRJNA207719: Tissue specific transcriptome profiling

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Results for tbr1b_tbx16+tbx16l+tbx2a+tbx2b

Z-value: 1.85

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Transcription factors associated with tbr1b_tbx16+tbx16l+tbx2a+tbx2b

Gene Symbol Gene ID Gene Info
ENSDARG00000004712 T-box brain transcription factor 1b
ENSDARG00000006120 T-box transcription factor 2b
ENSDARG00000006939 T-box transcription factor 16, like
ENSDARG00000007329 T-box transcription factor 16
ENSDARG00000018025 T-box transcription factor 2a
ENSDARG00000109541 T-box transcription factor 2a
ENSDARG00000116135 T-box transcription factor 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tbr1bdr11_v1_chr9_-_51436377_51436377-0.951.1e-02Click!
tbx16dr11_v1_chr8_-_51753604_51753604-0.951.4e-02Click!
tbx2bdr11_v1_chr15_+_27364394_27364394-0.847.5e-02Click!
tbx2adr11_v1_chr5_-_56513825_56513825-0.474.3e-01Click!
tbx6ldr11_v1_chr5_+_42280372_42280372-0.108.7e-01Click!

Activity profile of tbr1b_tbx16+tbx16l+tbx2a+tbx2b motif

Sorted Z-values of tbr1b_tbx16+tbx16l+tbx2a+tbx2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_51846224 2.59 ENSDART00000184663

chr17_+_26965351 2.12 ENSDART00000114215
ENSDART00000147192
grainyhead-like transcription factor 3
chr6_+_56141852 1.64 ENSDART00000149665
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr19_+_791538 1.57 ENSDART00000146554
ENSDART00000138406
transmembrane protein 79a
chr23_+_23232136 1.51 ENSDART00000126479
ENSDART00000187764
pleckstrin homology domain containing, family N member 1
chr22_+_661711 1.49 ENSDART00000113795
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr19_+_7735157 1.46 ENSDART00000186717
tuftelin 1b
chr19_-_7420867 1.44 ENSDART00000081741
RAB25, member RAS oncogene family a
chr7_+_38750871 1.37 ENSDART00000114238
ENSDART00000052325
ENSDART00000137001
coagulation factor II (thrombin)
chr2_+_36007449 1.34 ENSDART00000161837
laminin, gamma 2
chr3_-_32603191 1.27 ENSDART00000150997
si:ch73-248e21.7
chr1_-_49521407 1.24 ENSDART00000189845
ENSDART00000143474
zona pellucida glycoprotein 3c
chr2_-_42234484 1.17 ENSDART00000132617
ENSDART00000136690
ENSDART00000141358
apolipoprotein M
chr16_-_54455573 1.17 ENSDART00000075275
pyruvate kinase L/R
chr13_+_33606739 1.16 ENSDART00000026464
cofilin 1 (non-muscle), like
chr9_-_443451 1.12 ENSDART00000165642
si:dkey-11f4.14
chr21_+_5531138 1.10 ENSDART00000163825
lymphocyte antigen 6 family member M6
chr13_+_18533005 1.10 ENSDART00000136024
finTRIM family, member 14-like
chr11_+_37178271 1.10 ENSDART00000161771
inter-alpha-trypsin inhibitor heavy chain 3b
chr18_+_7591381 1.09 ENSDART00000136313
si:dkeyp-1h4.6
chr22_+_25715925 1.09 ENSDART00000150650
si:dkeyp-98a7.7
chr19_+_9305964 1.08 ENSDART00000136241
si:ch73-15n24.1
chr11_-_25257045 1.07 ENSDART00000130477
snail family zinc finger 1a
chr19_-_5332784 1.05 ENSDART00000010373
keratin, type 1, gene 19d
chr11_-_25257595 1.05 ENSDART00000123567
snail family zinc finger 1a
chr22_+_25693295 1.04 ENSDART00000123888
ENSDART00000150783
si:dkeyp-98a7.4
si:dkeyp-98a7.3
chr14_+_48862987 1.04 ENSDART00000167810
zgc:154054
chr11_+_6650966 1.00 ENSDART00000131236
si:dkey-246j7.1
chr7_-_53117131 0.97 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cadherin 1, type 1, E-cadherin (epithelial)
chr22_+_25720725 0.96 ENSDART00000150778
si:dkeyp-98a7.8
chr5_-_25037454 0.95 ENSDART00000027237
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr15_-_1590858 0.94 ENSDART00000081875
nanor
chr22_+_25681911 0.91 ENSDART00000113381
si:dkeyp-98a7.3
chr5_-_38170996 0.90 ENSDART00000145805
si:ch211-284e13.12
chr15_-_32131 0.89 ENSDART00000099074
ENSDART00000164323
si:zfos-411a11.2
chr14_+_21106444 0.88 ENSDART00000075744
ENSDART00000132363
aldolase b, fructose-bisphosphate
chr3_+_47245764 0.88 ENSDART00000193581
TNF superfamily member 14
chr22_+_25710148 0.87 ENSDART00000150446
si:dkeyp-98a7.4
chr14_+_17376940 0.87 ENSDART00000054590
ENSDART00000010148
spondin 2b, extracellular matrix protein
chr22_+_25687525 0.87 ENSDART00000135717
si:dkeyp-98a7.3
chr22_+_25704430 0.86 ENSDART00000143776
si:dkeyp-98a7.3
chr11_-_7380674 0.85 ENSDART00000014979
ENSDART00000103418
vitellogenin 3, phosvitinless
chr24_-_27419198 0.85 ENSDART00000141124
chemokine (C-C motif) ligand 34b, duplicate 4
chr25_+_4960509 0.85 ENSDART00000155984
si:ch73-265h17.4
chr24_-_26369185 0.85 ENSDART00000080039
leucine rich repeat containing 31
chr11_-_12198765 0.84 ENSDART00000104203
ENSDART00000128364
ENSDART00000166887
ENSDART00000041533
kertain 95
chr22_+_25734180 0.84 ENSDART00000143367
si:dkeyp-98a7.9
chr5_+_43006422 0.83 ENSDART00000009182
aquaporin 3a
chr7_-_38638809 0.81 ENSDART00000144341
six-cysteine containing astacin protease 4
chr5_-_68022631 0.81 ENSDART00000143199
WAS protein family, member 3a
chr24_-_36593876 0.80 ENSDART00000160901

chr23_+_19814371 0.80 ENSDART00000182897
emerin (Emery-Dreifuss muscular dystrophy)
chr5_-_44843738 0.79 ENSDART00000003926
fructose-1,6-bisphosphatase 1a
chr21_-_22928214 0.78 ENSDART00000182760
duboraya
chr1_-_7603734 0.77 ENSDART00000009315
myxovirus (influenza) resistance B
chr21_+_25226558 0.77 ENSDART00000168480
syncollin, tandem duplicate 2
chr21_-_3700334 0.76 ENSDART00000137844
ATPase phospholipid transporting 8B1
chr16_-_31686602 0.75 ENSDART00000170357
complement component 1, s subcomponent
chr22_+_16022211 0.75 ENSDART00000062618
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr18_+_29156827 0.74 ENSDART00000137587
ENSDART00000135633
PTPRF interacting protein, binding protein 2a (liprin beta 2)
chr12_-_10567188 0.74 ENSDART00000144283
myoferlin
chr10_+_38417512 0.73 ENSDART00000112457
SAM domain, SH3 domain and nuclear localisation signals 1b
chr4_+_14981854 0.73 ENSDART00000067046
cation/H+ exchanger protein 1
chr7_-_19614916 0.73 ENSDART00000169029
zgc:194655
chr22_-_24757785 0.72 ENSDART00000078225
vitellogenin 5
chr3_+_43086548 0.72 ENSDART00000163579
si:dkey-43p13.5
chr17_-_8907668 0.72 ENSDART00000155996
ENSDART00000155624
NK-lysin tandem duplicate 1
chr5_-_32505109 0.72 ENSDART00000188219
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr16_-_20312146 0.71 ENSDART00000134980
si:dkeyp-86h10.3
chr3_-_32958505 0.71 ENSDART00000147374
ENSDART00000136919
caspase 6, apoptosis-related cysteine peptidase, like 1
chr7_-_5070794 0.70 ENSDART00000097877
leukotriene B4 receptor 2a
chr2_+_27403300 0.70 ENSDART00000099180
ELOVL fatty acid elongase 8a
chr7_+_13988075 0.69 ENSDART00000186812
furin (paired basic amino acid cleaving enzyme) a
chr8_-_24252933 0.69 ENSDART00000057624
zgc:110353
chr3_-_15451097 0.68 ENSDART00000163836
Danio rerio linker for activation of T cells (lat), mRNA.
chr12_+_6002715 0.68 ENSDART00000114961
si:ch211-131k2.3
chr8_+_20994433 0.68 ENSDART00000141736
si:dkeyp-82a1.8
chr23_+_9867483 0.68 ENSDART00000023099
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr20_-_40360571 0.67 ENSDART00000144768
sphingomyelin phosphodiesterase, acid-like 3A
chr15_-_43164591 0.67 ENSDART00000171305
adaptor-related protein complex 1, sigma 3 subunit, a
chr7_-_8014186 0.66 ENSDART00000190012
si:cabz01030277.1
chr13_-_25767210 0.66 ENSDART00000131792
PDZ and LIM domain 1 (elfin)
chr6_+_34868156 0.66 ENSDART00000149364
interleukin 23 receptor
chr7_-_54320088 0.66 ENSDART00000172396
Fas (tnfrsf6)-associated via death domain
chr7_+_69841017 0.66 ENSDART00000169107

chr18_-_7539166 0.66 ENSDART00000133541
si:dkey-30c15.2
chr12_-_43711918 0.65 ENSDART00000193110

chr22_-_34609528 0.65 ENSDART00000190781
ENSDART00000171712
telomeric repeat binding factor 2, interacting protein
chr16_+_23978978 0.65 ENSDART00000058964
ENSDART00000135084
apolipoprotein A-II
chr20_-_26846028 0.65 ENSDART00000136687
myosin light chain kinase family, member 4b
chr7_-_52417777 0.64 ENSDART00000110265
myocardial zonula adherens protein
chr19_-_5372572 0.64 ENSDART00000151326
keratin 17
chr22_+_15315655 0.64 ENSDART00000141249
sulfotransferase family 3, cytosolic sulfotransferase 3
chr10_-_32524035 0.63 ENSDART00000137608
diacylglycerol O-acyltransferase 2
chr12_-_4206869 0.63 ENSDART00000106572
si:dkey-32n7.9
chr1_-_52505279 0.62 ENSDART00000052907
aspartoacylase (aminocyclase) 3, tandem duplicate 1
chr22_-_9649627 0.61 ENSDART00000164721
si:dkey-286j17.4
chr2_-_30182353 0.61 ENSDART00000019149
ribosomal protein L7
chr4_-_12790886 0.61 ENSDART00000182535
ENSDART00000067131
ENSDART00000186426
interleukin-1 receptor-associated kinase 3
chr11_-_11575070 0.61 ENSDART00000142208
zgc:110712
chr13_-_15702672 0.61 ENSDART00000144445
ENSDART00000168950
creatine kinase, brain a
chr10_+_38610741 0.61 ENSDART00000126444
matrix metallopeptidase 13a
chr13_-_41908583 0.60 ENSDART00000136515
inositol polyphosphate multikinase a
chr7_+_15329819 0.60 ENSDART00000006018
mesoderm posterior aa
chr20_+_15600167 0.59 ENSDART00000171991
Fas ligand (TNF superfamily, member 6)
chr1_-_6028876 0.59 ENSDART00000168117
si:ch1073-345a8.1
chr3_+_12848123 0.59 ENSDART00000166689
si:ch211-8c17.4
chr25_+_36292057 0.59 ENSDART00000152329
brambleberry
chr25_+_25085349 0.58 ENSDART00000192166
si:ch73-182e20.4
chr9_-_42873700 0.58 ENSDART00000125953
titin, tandem duplicate 1
chr21_-_34951265 0.58 ENSDART00000135222
lipase, member Ia
chr7_+_3357973 0.57 ENSDART00000172853
si:ch211-285c6.5
chr12_+_27231212 0.57 ENSDART00000133023
ENSDART00000123739
transmembrane protein 106A
chr15_-_47848544 0.57 ENSDART00000098711
eukaryotic translation initiation factor 3, subunit K
chr24_-_34680956 0.57 ENSDART00000171009
catenin (cadherin-associated protein), alpha 1
chr19_-_5369486 0.57 ENSDART00000105004
keratin 17
chr8_+_36354125 0.57 ENSDART00000109439
si:zfos-367g9.1
chr7_+_2797795 0.57 ENSDART00000161208
si:ch211-217i17.1
chr6_+_36839509 0.57 ENSDART00000190605
ENSDART00000104160
zgc:110788
chr9_+_48108174 0.56 ENSDART00000077260
chemokine (C-X-C motif) receptor 2
chr16_+_38201840 0.56 ENSDART00000044971
myosin IE, b
chr19_+_30990815 0.56 ENSDART00000134645
syncoilin, intermediate filament protein
chr22_-_17652112 0.56 ENSDART00000189205
histocompatibility (minor) HA-1 b
chr12_-_14143344 0.55 ENSDART00000152742
bucky ball 2-like
chr9_+_54984900 0.55 ENSDART00000191622
motile sperm domain containing 2
chr9_+_33423170 0.54 ENSDART00000141542
si:dkey-216e24.9
chr3_-_53465223 0.54 ENSDART00000057123
ENSDART00000125515
ENSDART00000143096
nuclear receptor subfamily 5, group A, member 5
chr21_+_21010786 0.54 ENSDART00000079692
nodal-related 1
chr2_-_59247811 0.53 ENSDART00000141384
finTRIM family, member 32
chr20_-_14114078 0.53 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
chr6_+_21062416 0.52 ENSDART00000141643
si:dkey-91f15.1
chr9_-_40011673 0.52 ENSDART00000184726
si:zfos-1425h8.1
chr22_+_9939901 0.52 ENSDART00000169777
ENSDART00000081420
zgc:171686
chr1_-_52498146 0.51 ENSDART00000122217
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr22_+_7439186 0.51 ENSDART00000190667
zgc:92041
chr22_+_38762693 0.51 ENSDART00000015016
ENSDART00000150187
alkaline phosphatase, intestinal, tandem duplicate 1
chr10_-_1961930 0.51 ENSDART00000122446
teratocarcinoma-derived growth factor 1
chr5_+_27525477 0.50 ENSDART00000051491
secreted frizzled-related protein 1a
chr16_+_29516098 0.50 ENSDART00000174895
cathepsin S, ortholog 2, tandem duplicate 2
chr13_-_27354003 0.50 ENSDART00000101479
ENSDART00000044652
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr19_+_917852 0.50 ENSDART00000082466
transforming growth factor beta receptor 2a
chr7_+_15324830 0.50 ENSDART00000189088
mesoderm posterior aa
chr23_-_16734009 0.50 ENSDART00000125449
si:ch211-224l10.4
chr8_+_48848200 0.50 ENSDART00000130673
tumor protein p73
chr21_-_41870029 0.50 ENSDART00000182035
endonuclease, polyU-specific 2
chr19_-_34999379 0.50 ENSDART00000051751
zgc:113424
chr24_-_18919562 0.50 ENSDART00000144244
ENSDART00000106188
ENSDART00000182518
carboxypeptidase A6
chr2_-_53481912 0.50 ENSDART00000189610
hydroxysteroid (11-beta) dehydrogenase 1-like b
chr7_+_19482084 0.50 ENSDART00000173873
si:ch211-212k18.7
chr16_+_21790870 0.50 ENSDART00000155039
tripartite motif containing 108
chr6_-_38930726 0.49 ENSDART00000154151
histone deacetylase 7b
chr10_-_11376491 0.49 ENSDART00000145346
placenta-specific 8, tandem duplicate 2
chr7_-_18508815 0.49 ENSDART00000173539
regulator of G protein signaling 12a
chr3_-_36750068 0.48 ENSDART00000173388
ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1
chr8_+_29593986 0.48 ENSDART00000077642
atonal bHLH transcription factor 1a
chr17_+_34186632 0.48 ENSDART00000014306
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr24_+_27511734 0.48 ENSDART00000105771
chemokine (C-X-C motif) ligand 32b, duplicate 1
chr20_+_35857399 0.48 ENSDART00000102611
CD2-associated protein
chr3_-_49514874 0.48 ENSDART00000167179
anti-silencing function 1Ba histone chaperone
chr15_+_32711663 0.48 ENSDART00000157854
ENSDART00000167515
periostin, osteoblast specific factor b
chr7_+_6969909 0.48 ENSDART00000189886
actinin alpha 3b
chr11_-_21304452 0.48 ENSDART00000163008
si:dkey-85p17.3
chr15_-_17099560 0.48 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr5_-_4204580 0.48 ENSDART00000049197
ENSDART00000132130
si:ch211-283g2.1
chr22_+_1123110 0.47 ENSDART00000171017
si:ch1073-181h11.2
chr1_+_59070762 0.47 ENSDART00000100195
si:ch1073-110a20.7
chr4_-_13509946 0.47 ENSDART00000134720
interferon, gamma 1-2
chr16_-_32233463 0.47 ENSDART00000102016
calcium homeostasis modulator family member 6
chr15_-_41689684 0.46 ENSDART00000143447
splA/ryanodine receptor domain and SOCS box containing 4b
chr6_-_15639087 0.46 ENSDART00000128940
ENSDART00000183092
melanophilin a
chr15_-_5580093 0.46 ENSDART00000143726
WD repeat domain 62
chr1_+_51615506 0.46 ENSDART00000152767
zgc:165656
chr3_+_30968176 0.46 ENSDART00000186266
perforin 1.9
chr2_-_14793343 0.45 ENSDART00000132264
si:ch73-366i20.1
chr25_-_37322081 0.45 ENSDART00000128285
immunoglobulin light 4 variable 10
chr22_-_23000815 0.45 ENSDART00000137111
protein tyrosine phosphatase, receptor type, C
chr22_+_5478353 0.45 ENSDART00000160596
tubulin polymerization promoting protein
chr1_-_52447364 0.45 ENSDART00000140740
si:ch211-217k17.10
chr5_-_42878178 0.45 ENSDART00000162981
C-X-C motif chemokine ligand 11
chr22_+_9772754 0.45 ENSDART00000130194

chr22_-_4439311 0.45 ENSDART00000169317
ubiquitin-like with PHD and ring finger domains 1
chr10_-_13116337 0.44 ENSDART00000164568
muscle, skeletal, receptor tyrosine kinase
chr25_+_11002640 0.44 ENSDART00000156646
ENSDART00000073383
major histocompatibility complex class I LGA
chr6_+_36877968 0.44 ENSDART00000155187
TRAF3 interacting protein 2-like
chr1_-_11616295 0.44 ENSDART00000188891
si:dkey-26i13.5
chr2_-_51330642 0.44 ENSDART00000163043
si:dkeyp-104b3.21
chr2_+_11029138 0.44 ENSDART00000138737
ENSDART00000081058
ENSDART00000153662
acyl-CoA thioesterase 11a
chr6_-_21726758 0.44 ENSDART00000083085
myotubularin related protein 14
chr8_+_36142734 0.43 ENSDART00000159361
ENSDART00000161194
major histocompatibility complex class II integral membrane beta chain gene
chr18_-_48550426 0.43 ENSDART00000145189
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1
chr23_+_24085531 0.43 ENSDART00000139710
tubulin tyrosine ligase-like family, member 10
chr8_-_25327809 0.43 ENSDART00000137242
EPS8-like 3b
chr22_+_26600834 0.43 ENSDART00000157411
adenylate cyclase 9
chr7_+_25221757 0.43 ENSDART00000173551
exocyst complex component 6B
chr1_+_56873359 0.43 ENSDART00000152713
si:ch211-152f2.2
chr17_-_27976031 0.42 ENSDART00000154829
platelet-activating factor receptor
chr6_+_40794015 0.42 ENSDART00000144479
GATA binding protein 2b
chr10_+_21899753 0.42 ENSDART00000080155
histamine receptor H2b
chr7_+_30051880 0.42 ENSDART00000075609
proline-serine-threonine phosphatase interacting protein 1b
chr2_+_45081489 0.42 ENSDART00000123966
cholinergic receptor, nicotinic, gamma

Network of associatons between targets according to the STRING database.

First level regulatory network of tbr1b_tbx16+tbx16l+tbx2a+tbx2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.4 1.5 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.3 1.3 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.3 0.9 GO:0046351 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.3 0.8 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045) hypoblast development(GO:0090008)
0.3 0.8 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.2 0.7 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.2 0.7 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.2 1.7 GO:0002526 acute inflammatory response(GO:0002526) acute-phase response(GO:0006953)
0.2 0.6 GO:0071706 tumor necrosis factor production(GO:0032640) tumor necrosis factor superfamily cytokine production(GO:0071706)
0.2 0.7 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 0.7 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.2 1.0 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.2 0.5 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.2 0.5 GO:0044785 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.2 0.6 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 0.3 GO:0034087 establishment of mitotic sister chromatid cohesion(GO:0034087)
0.1 2.6 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 0.3 GO:0048320 axial mesoderm formation(GO:0048320) axial mesodermal cell differentiation(GO:0048321) axial mesodermal cell fate commitment(GO:0048322) axial mesodermal cell fate specification(GO:0048327)
0.1 2.0 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.4 GO:0070228 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.1 0.5 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.6 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 0.6 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.1 0.4 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.1 0.5 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.6 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 0.2 GO:0002432 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.1 0.4 GO:0060043 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.1 0.4 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.1 1.2 GO:0048382 mesendoderm development(GO:0048382)
0.1 0.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.3 GO:0045218 cell-cell junction maintenance(GO:0045217) zonula adherens maintenance(GO:0045218)
0.1 0.3 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.1 0.9 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.1 0.3 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.1 1.5 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.7 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.1 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.3 GO:0070199 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.1 0.2 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.1 0.4 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 0.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 0.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.7 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.3 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.8 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.4 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.9 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.4 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.1 0.7 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.2 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.2 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 1.0 GO:0016203 muscle attachment(GO:0016203)
0.1 0.8 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.2 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.1 0.3 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.1 0.2 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.1 0.4 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.1 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.8 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 2.1 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 1.9 GO:0032355 response to estradiol(GO:0032355)
0.0 0.9 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.4 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:0015911 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.0 0.3 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.7 GO:0032264 IMP salvage(GO:0032264)
0.0 0.4 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.3 GO:0071623 negative regulation of leukocyte chemotaxis(GO:0002689) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.4 GO:0003262 cell fate determination(GO:0001709) endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.0 0.3 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.0 0.9 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.4 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.4 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.5 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.3 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.6 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.1 GO:0052576 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.0 0.2 GO:0048901 anterior lateral line neuromast development(GO:0048901) anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.0 0.3 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.8 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 1.5 GO:0043113 receptor clustering(GO:0043113)
0.0 0.3 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 0.4 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.0 1.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0030238 female sex determination(GO:0030237) male sex determination(GO:0030238)
0.0 0.5 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0070640 vitamin D3 metabolic process(GO:0070640)
0.0 0.1 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.8 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.1 GO:0072679 thymocyte migration(GO:0072679)
0.0 0.6 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.1 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.6 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.4 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 1.7 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.2 GO:0043102 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.5 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.4 GO:0001941 postsynaptic membrane organization(GO:0001941) presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.3 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.2 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.2 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.0 0.1 GO:0051661 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.7 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.0 0.2 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.3 GO:0003207 cardiac chamber formation(GO:0003207)
0.0 0.1 GO:0060437 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.0 0.5 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.3 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.6 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.4 GO:0003128 heart field specification(GO:0003128)
0.0 0.1 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.1 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.3 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.9 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.3 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.0 0.2 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.7 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.4 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.2 GO:0035587 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.6 GO:0051923 sulfation(GO:0051923)
0.0 0.3 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.1 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.0 0.4 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.1 GO:0021698 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698)
0.0 0.2 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.3 GO:0032438 melanosome organization(GO:0032438)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.9 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 1.1 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 1.8 GO:0031101 fin regeneration(GO:0031101)
0.0 0.1 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.3 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.6 GO:0039021 pronephric glomerulus development(GO:0039021)
0.0 0.5 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:0086003 cardiac muscle cell contraction(GO:0086003)
0.0 0.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 1.3 GO:0006959 humoral immune response(GO:0006959)
0.0 0.5 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.1 GO:0042987 Notch receptor processing(GO:0007220) beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.1 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.0 GO:0014826 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.8 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.0 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.3 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.4 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:0010165 response to X-ray(GO:0010165)
0.0 0.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.0 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222)
0.0 0.2 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0033505 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.0 0.0 GO:1903722 regulation of centriole elongation(GO:1903722) negative regulation of centriole elongation(GO:1903723)
0.0 0.1 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.1 GO:1901317 regulation of sperm motility(GO:1901317)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.6 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 1.8 GO:0009617 response to bacterium(GO:0009617)
0.0 0.2 GO:0030168 platelet activation(GO:0030168)
0.0 0.4 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.0 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.2 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 1.5 GO:0006954 inflammatory response(GO:0006954)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.5 GO:0048821 erythrocyte development(GO:0048821)
0.0 0.0 GO:0016038 absorption of visible light(GO:0016038)
0.0 0.1 GO:0002761 regulation of myeloid leukocyte differentiation(GO:0002761)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.6 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.1 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.0 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:1990923 PET complex(GO:1990923)
0.1 0.5 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 1.7 GO:0030057 desmosome(GO:0030057)
0.1 0.4 GO:0097433 dense body(GO:0097433)
0.1 0.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 0.2 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.1 1.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.3 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.3 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.1 0.3 GO:0031415 NatA complex(GO:0031415)
0.1 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.2 GO:0031511 Mis6-Sim4 complex(GO:0031511)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0000939 condensed chromosome inner kinetochore(GO:0000939) condensed nuclear chromosome inner kinetochore(GO:0000941)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.0 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0070187 telosome(GO:0070187)
0.0 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.8 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.7 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.6 GO:0000792 heterochromatin(GO:0000792)
0.0 0.1 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 3.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.4 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 1.3 GO:0005902 microvillus(GO:0005902)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 1.3 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.4 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 1.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.8 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 0.8 GO:0001726 ruffle(GO:0001726)
0.0 0.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.7 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.4 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0072686 mitotic spindle(GO:0072686)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.5 1.5 GO:1901612 cardiolipin binding(GO:1901612)
0.3 0.9 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.2 0.7 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.2 1.6 GO:0045735 nutrient reservoir activity(GO:0045735)
0.2 0.8 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.2 0.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2 1.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 0.7 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 1.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.6 GO:0051916 C-X-C chemokine receptor activity(GO:0016494) granulocyte colony-stimulating factor binding(GO:0051916)
0.1 1.5 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.6 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.1 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.1 1.5 GO:0070697 activin receptor binding(GO:0070697)
0.1 0.9 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.5 GO:0032190 acrosin binding(GO:0032190)
0.1 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 0.4 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.7 GO:0034584 piRNA binding(GO:0034584)
0.1 0.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.2 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.6 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.3 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 0.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.9 GO:0002020 protease binding(GO:0002020)
0.1 0.2 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.9 GO:0031386 protein tag(GO:0031386)
0.1 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.2 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.6 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.8 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.2 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.7 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.4 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.8 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 0.2 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.2 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 2.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.2 GO:0030251 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.0 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.3 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0070052 collagen V binding(GO:0070052)
0.0 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.9 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.0 0.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.5 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.5 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.3 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 1.9 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0043394 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.0 0.4 GO:0070035 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.7 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.4 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 1.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.5 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.3 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.4 GO:0045503 dynein light chain binding(GO:0045503)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.0 0.3 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 5.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.3 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 4.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 1.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 1.4 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0016918 retinal binding(GO:0016918)
0.0 2.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.0 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.2 GO:0005163 death receptor binding(GO:0005123) nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 1.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.6 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 2.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 1.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 0.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 1.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 2.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.5 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.1 PID ATR PATHWAY ATR signaling pathway
0.0 0.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.0 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.2 PID FGF PATHWAY FGF signaling pathway
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.7 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 1.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.0 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.9 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 1.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.4 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA