Project

PRJNA207719: Tissue specific transcriptome profiling

Navigation
Downloads

Results for tal1

Z-value: 2.11

Motif logo

Transcription factors associated with tal1

Gene Symbol Gene ID Gene Info
ENSDARG00000019930 T-cell acute lymphocytic leukemia 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tal1dr11_v1_chr22_+_16535575_16535575-0.424.8e-01Click!

Activity profile of tal1 motif

Sorted Z-values of tal1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_19790962 1.83 ENSDART00000142228
filamin A, alpha (actin binding protein 280)
chr25_-_18470695 1.77 ENSDART00000034377
carboxypeptidase A5
chr3_-_3209432 1.59 ENSDART00000140635
si:ch211-229i14.2
chr10_-_342564 1.58 ENSDART00000157633
vasodilator stimulated phosphoprotein a
chr3_+_58833306 1.55 ENSDART00000113223
immunoglobulin light 1 constant 3
chr16_-_41990421 1.38 ENSDART00000055921
PYD and CARD domain containing
chr22_-_10541372 1.38 ENSDART00000179708
si:dkey-42i9.4
chr21_+_5531138 1.31 ENSDART00000163825
lymphocyte antigen 6 family member M6
chr13_+_669177 1.19 ENSDART00000190085

chr7_+_71535045 1.15 ENSDART00000047069
thymidylate synthetase
chr3_-_61181018 1.15 ENSDART00000187970
parvalbumin 4
chr19_+_48117995 1.14 ENSDART00000170865
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
chr23_+_44614056 1.12 ENSDART00000188379
enolase 3, (beta, muscle)
chr12_+_13256415 1.11 ENSDART00000144542
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr7_+_39389273 1.06 ENSDART00000191298
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr6_+_40629066 1.04 ENSDART00000103757
solute carrier family 6 (neurotransmitter transporter), member 11a
chr5_-_60885935 1.03 ENSDART00000128350
RAD51 paralog D
chr3_+_3598555 1.02 ENSDART00000191152

chr3_+_4266289 1.00 ENSDART00000101636
si:dkey-73p2.1
chr2_+_45191049 0.99 ENSDART00000165392
chemokine (C-C motif) ligand 20a, duplicate 3
chr7_+_8456999 0.99 ENSDART00000172880
jacalin 4
chr4_+_77943184 0.98 ENSDART00000159094
protein kinase C and casein kinase substrate in neurons 2
chr5_+_338154 0.97 ENSDART00000191743
ring finger protein 170
chr21_+_10577527 0.97 ENSDART00000165070
ENSDART00000127963
collagen and calcium binding EGF domains 1
chr22_+_20720808 0.96 ENSDART00000171321
si:dkey-211f22.5
chr19_-_25519612 0.95 ENSDART00000133150
si:dkey-202e17.1
chr2_-_7666021 0.95 ENSDART00000180007

chr1_-_59141715 0.95 ENSDART00000164941
ENSDART00000138870
si:ch1073-110a20.1
chr7_-_8438657 0.94 ENSDART00000173054
si:dkeyp-32g11.8
chr13_-_438705 0.93 ENSDART00000082142

chr9_+_307863 0.93 ENSDART00000163474
SH3 and cysteine rich domain 3
chr20_+_2281933 0.92 ENSDART00000137579
si:ch73-18b11.2
chr17_-_2584423 0.90 ENSDART00000013506
zona pellucida glycoprotein 3, tandem duplicate 2
chr4_+_38550788 0.90 ENSDART00000157412
si:ch211-209n20.1
chr24_-_6029314 0.87 ENSDART00000136155
finTRIM family, member 60
chr11_+_6136220 0.85 ENSDART00000082223
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr21_+_5974590 0.84 ENSDART00000098499
deoxycytidine kinase
chr3_-_3939785 0.84 ENSDART00000049593
un-named sa1506
chr23_+_16807945 0.83 ENSDART00000080660
zgc:114081
chr2_+_11031360 0.82 ENSDART00000180020
ENSDART00000145093
acyl-CoA thioesterase 11a
chr25_-_18454016 0.81 ENSDART00000005877
carboxypeptidase A1 (pancreatic)
chr20_+_172162 0.81 ENSDART00000168765

chr9_+_33220342 0.81 ENSDART00000100893
ENSDART00000113451
si:ch211-125e6.13
chr21_-_217589 0.80 ENSDART00000185017

chr23_+_16807785 0.79 ENSDART00000146992
zgc:114081
chr22_-_26353916 0.78 ENSDART00000077958
calpain 2, (m/II) large subunit b
chr4_-_16354292 0.78 ENSDART00000139919
lumican
chr15_+_47525073 0.77 ENSDART00000067583
SID1 transmembrane family, member 2
chr3_-_4574372 0.77 ENSDART00000172023
ENSDART00000168724
finTRIM family, member 50
chr3_-_47235997 0.76 ENSDART00000047071
transmembrane p24 trafficking protein 1a
chr7_+_2455344 0.76 ENSDART00000172942
si:dkey-125e8.4
chr1_-_52494122 0.75 ENSDART00000131407
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr9_+_51225345 0.75 ENSDART00000132896
fibroblast activation protein, alpha
chr8_-_27687095 0.75 ENSDART00000086946
Moloney leukemia virus 10b, tandem duplicate 1
chr2_-_45191319 0.74 ENSDART00000192272

chr25_+_15933411 0.73 ENSDART00000191581
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr3_-_44012748 0.72 ENSDART00000167248
ENSDART00000157463
ENSDART00000159111
interleukin 4 receptor, tandem duplicate 1
chr18_+_38321039 0.72 ENSDART00000132534
ENSDART00000111260
ENSDART00000192806
ALX homeobox 4b
chr7_+_56577522 0.72 ENSDART00000149130
ENSDART00000149624
haptoglobin
chr3_+_3545825 0.72 ENSDART00000109060

chr12_-_48168135 0.72 ENSDART00000186624
phosphatase domain containing, paladin 1a
chr17_-_2595736 0.72 ENSDART00000128797
zona pellucida glycoprotein 3, tandem duplicate 2
chr19_-_48010490 0.70 ENSDART00000159938
zgc:158376
chr7_+_35229805 0.70 ENSDART00000173911
tubulin polymerization-promoting protein family member 3
chr22_+_987788 0.70 ENSDART00000149486
differentially expressed in FDCP 6b homolog (mouse)
chr3_+_54581987 0.67 ENSDART00000018071
eukaryotic translation initiation factor 3, subunit G
chr1_+_55703120 0.67 ENSDART00000141089
adhesion G protein-coupled receptor E6
chr2_+_3452590 0.67 ENSDART00000153935
cytochrome P450, family 8, subfamily B, polypeptide 2
chr1_+_277731 0.65 ENSDART00000133431
centromere protein E
chr8_-_1219815 0.65 ENSDART00000016800
ENSDART00000149969
zinc finger protein 367
chr5_+_25762271 0.65 ENSDART00000181323
transmembrane protein 2
chr20_-_26929685 0.62 ENSDART00000132556
finTRIM family, member 79
chr9_-_105135 0.62 ENSDART00000180126

chr3_-_7990516 0.62 ENSDART00000167877
si:ch211-175l6.2
chr3_-_180860 0.62 ENSDART00000059956
ENSDART00000192506
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr22_+_5971404 0.61 ENSDART00000122153

chr5_-_65000312 0.61 ENSDART00000192893
zgc:110283
chr7_+_26029672 0.61 ENSDART00000101126
arachidonate 12-lipoxygenase
chr1_-_513762 0.61 ENSDART00000148162
ENSDART00000144606
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr3_-_34098731 0.61 ENSDART00000150999
immunoglobulin heavy variable 5-3
chr17_-_2573021 0.61 ENSDART00000074181
zona pellucida glycoprotein 3, tandem duplicate 2
chr16_+_9495583 0.60 ENSDART00000150750
ENSDART00000150457
Pim proto-oncogene, serine/threonine kinase, related 208
chr25_+_25202213 0.60 ENSDART00000150744
chemokine (C-C motif) ligand 39, duplicate 10
chr19_-_3783141 0.60 ENSDART00000162260
bloodthirsty-related gene family, member 19
chr11_+_42587900 0.59 ENSDART00000167529
ankyrin repeat and SOCS box containing 14a
chr6_-_35439406 0.59 ENSDART00000073784
regulator of G protein signaling 5a
chr22_+_36704764 0.59 ENSDART00000146662
tripartite motif containing 35-33
chr2_-_44255537 0.58 ENSDART00000011188
ENSDART00000093298
ATPase Na+/K+ transporting subunit alpha 2
chr8_-_1051438 0.58 ENSDART00000067093
ENSDART00000170737
SET and MYND domain containing 1b
chr7_-_8470860 0.58 ENSDART00000172793
hypothetical protein LOC564481
chr15_+_38299563 0.58 ENSDART00000099375
si:dkey-24p1.6
chr17_-_2578026 0.58 ENSDART00000065821
zona pellucida glycoprotein 3, tandem duplicate 2
chr18_+_5547185 0.57 ENSDART00000193977
nicotinamide nucleotide transhydrogenase 2
chr7_-_6346859 0.57 ENSDART00000172913
si:ch73-368j24.11
chr22_-_10541712 0.56 ENSDART00000013933
si:dkey-42i9.4
chr1_+_55002583 0.56 ENSDART00000037250
si:ch211-196h16.12
chr9_+_44994214 0.55 ENSDART00000141434
retinol saturase (all-trans-retinol 13,14-reductase) like
chr4_-_58964138 0.55 ENSDART00000150259
si:ch211-64i20.3
chr6_-_13206255 0.55 ENSDART00000065373
eukaryotic translation elongation factor 1 beta 2
chr3_+_2669813 0.55 ENSDART00000014205

chr17_+_53439606 0.54 ENSDART00000154946
si:zfos-1714f5.3
chr3_-_4760384 0.54 ENSDART00000108810

chr1_+_55452892 0.54 ENSDART00000122508

chr18_-_11729 0.53 ENSDART00000159781
WAS protein homolog associated with actin, golgi membranes and microtubules
chr19_-_27588842 0.53 ENSDART00000121643
si:dkeyp-46h3.2
chr15_+_47746176 0.53 ENSDART00000154481
ENSDART00000160914
StAR-related lipid transfer (START) domain containing 10
chr1_-_9644630 0.53 ENSDART00000123725
ENSDART00000161164
UDP glucuronosyltransferase 5 family, polypeptide B3
chr17_-_2590222 0.53 ENSDART00000185711

chr9_+_33217243 0.52 ENSDART00000053061
si:ch211-125e6.12
chr10_+_40629616 0.52 ENSDART00000147476

chr24_-_30275735 0.52 ENSDART00000168723
sorting nexin 7
chr21_-_31210749 0.51 ENSDART00000185356
zgc:152891
chr3_+_1179601 0.51 ENSDART00000173378
TRIO and F-actin binding protein b
chr4_-_77636185 0.51 ENSDART00000152915
ENSDART00000131964
si:dkey-61p9.9
chr1_+_292545 0.50 ENSDART00000148261
centromere protein E
chr2_-_51757328 0.50 ENSDART00000189286
si:ch211-9d9.1
chr21_+_53504 0.50 ENSDART00000170452
dimethylglycine dehydrogenase
chr25_+_37289088 0.50 ENSDART00000073438
si:dkey-234i14.9
chr4_+_77709678 0.49 ENSDART00000036856

chr5_-_7829657 0.49 ENSDART00000158374
PDZ and LIM domain 5a
chr1_-_53880639 0.49 ENSDART00000010543
LTV1 ribosome biogenesis factor
chr4_-_32456788 0.49 ENSDART00000151862
si:dkey-16p6.1
chr25_+_37290206 0.49 ENSDART00000086474
si:dkey-234i14.12
chr13_-_42560662 0.48 ENSDART00000124898

chr7_+_8358547 0.48 ENSDART00000173016
jacalin 7
chr4_+_50401133 0.48 ENSDART00000150644
si:dkey-156k2.7
chr22_+_18469004 0.48 ENSDART00000061430
cartilage intermediate layer protein 2
chr25_-_37501371 0.47 ENSDART00000160498

chr21_-_30293224 0.47 ENSDART00000101051
stem-loop binding protein 2
chr3_-_29977495 0.47 ENSDART00000077111
hydroxysteroid (17-beta) dehydrogenase 14
chr22_+_9262800 0.47 ENSDART00000143041
si:ch211-250k18.6
chr16_+_42772678 0.46 ENSDART00000155575
si:ch211-135n15.2
chr25_-_36369057 0.46 ENSDART00000064400
si:ch211-113a14.24
chr1_+_50293938 0.46 ENSDART00000084184
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
chr21_-_44081540 0.46 ENSDART00000130833

chr23_+_29908348 0.45 ENSDART00000186622
ENSDART00000150174
si:ch73-236e11.2
chr3_+_4726621 0.45 ENSDART00000184186

chr12_-_44151296 0.44 ENSDART00000168734
si:ch73-329n5.3
chr1_+_57235896 0.44 ENSDART00000152621
si:dkey-27j5.7
chr9_+_32178050 0.44 ENSDART00000169526
coenzyme Q10B
chr5_-_26181863 0.44 ENSDART00000098500
coiled-coil domain containing 125
chr2_-_59345920 0.44 ENSDART00000134662
finTRIM family, member 37
chr8_+_39570615 0.44 ENSDART00000142557
leucine zipper, putative tumor suppressor 1
chr21_+_2203316 0.43 ENSDART00000185659

chr14_+_17382803 0.43 ENSDART00000040383
si:ch211-255i20.3
chr20_-_54377933 0.43 ENSDART00000182664
ectonucleoside triphosphate diphosphohydrolase 5b
chr11_+_37909654 0.43 ENSDART00000172211
si:ch211-112f3.4
chr5_+_37744625 0.43 ENSDART00000014031
D4, zinc and double PHD fingers family 2
chr23_-_45319592 0.42 ENSDART00000189861
coiled-coil domain containing 171
chr7_-_6415991 0.42 ENSDART00000173349
Histone H3.2
chr1_+_56823437 0.42 ENSDART00000129527
si:ch211-1f22.5
chr13_-_50565338 0.42 ENSDART00000062684
B cell linker
chr17_+_132555 0.41 ENSDART00000158159
zgc:77287
chr5_-_30984010 0.41 ENSDART00000182367
spinster homolog 3 (Drosophila)
chr14_-_25928899 0.41 ENSDART00000143518
GTPase activating protein (SH3 domain) binding protein 1
chr2_-_32624577 0.41 ENSDART00000112797
si:dkeyp-73d8.6
chr16_-_19568795 0.41 ENSDART00000185141
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr3_-_61203203 0.41 ENSDART00000171787
parvalbumin 1
chr7_+_5964296 0.41 ENSDART00000173380
si:dkey-23a13.17
chr16_-_48914757 0.41 ENSDART00000166740

chr20_+_25225112 0.40 ENSDART00000153088
ENSDART00000127291
ENSDART00000130494
monooxygenase, DBH-like 1
chr8_+_28469054 0.40 ENSDART00000062716
solute carrier family 52 (riboflavin transporter), member 3
chr23_-_18057270 0.40 ENSDART00000173385
zgc:92287
chr10_+_4987766 0.40 ENSDART00000121959
si:ch73-234b20.5
chr17_-_7457698 0.40 ENSDART00000144492
ENSDART00000172035
si:ch211-278p9.1
chr4_+_2267641 0.40 ENSDART00000165503
si:ch73-89b15.3
chr24_+_5789582 0.39 ENSDART00000141504

chr7_+_33132074 0.39 ENSDART00000073554
zgc:153219
chr6_-_51573975 0.39 ENSDART00000073865
retinoblastoma-like 1 (p107)
chr7_+_25053331 0.39 ENSDART00000173998
si:dkey-23i12.7
chr7_+_56577906 0.39 ENSDART00000184023
haptoglobin
chr8_+_40275830 0.39 ENSDART00000164414
ORAI calcium release-activated calcium modulator 1a
chr15_-_551177 0.39 ENSDART00000066774
ENSDART00000154617
transgelin
chr18_+_5454341 0.39 ENSDART00000192649
DTW domain containing 1
chr7_+_35229645 0.39 ENSDART00000144327
tubulin polymerization-promoting protein family member 3
chr12_-_44148073 0.38 ENSDART00000166273
si:ch73-329n5.1
chr1_-_56717813 0.38 ENSDART00000159196

chr7_-_6470431 0.38 ENSDART00000081359
zgc:110425
chr19_-_10432134 0.38 ENSDART00000081440
interleukin 11b
chr4_+_37952218 0.38 ENSDART00000186865
si:dkeyp-82b4.2
chr17_+_53156530 0.38 ENSDART00000126277
ENSDART00000156774
diphthamine biosynthesis 6
chr5_-_8907819 0.38 ENSDART00000188523
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr1_-_55118745 0.38 ENSDART00000133915
SERTA domain containing 2a
chr7_+_24523017 0.38 ENSDART00000077047
bloodthirsty-related gene family, member 9
chr17_+_20607487 0.37 ENSDART00000154123
si:ch73-288o11.5
chr4_-_43911462 0.37 ENSDART00000189056
ENSDART00000162441
ENSDART00000171367
zinc finger protein 1104
chr2_-_59265521 0.37 ENSDART00000146341
ENSDART00000097799
finTRIM family, member 33
chr7_-_7984015 0.37 ENSDART00000163203
si:cabz01030277.1
chr22_+_38310957 0.37 ENSDART00000040550
Tnf receptor-associated factor 5
chr15_-_4485828 0.36 ENSDART00000062868
transcription factor Dp-2
chr4_-_65747476 0.36 ENSDART00000142421
si:dkey-28k24.2
chr5_-_15692030 0.36 ENSDART00000099545

chr2_-_59247811 0.36 ENSDART00000141384
finTRIM family, member 32
chr4_+_8638622 0.36 ENSDART00000186829
wingless-type MMTV integration site family, member 5b
chr17_+_1627379 0.36 ENSDART00000184050

chr2_-_36497113 0.36 ENSDART00000109291

chr19_-_24555935 0.36 ENSDART00000132660
ENSDART00000162801
polymerase (RNA) III (DNA directed) polypeptide G like a
chr4_+_75577480 0.35 ENSDART00000188196
si:ch211-227e10.1
chr6_+_27315173 0.35 ENSDART00000108831
espin like a
chr3_-_45848043 0.35 ENSDART00000055132
insulin-like growth factor binding protein, acid labile subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of tal1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.3 1.0 GO:0042148 strand invasion(GO:0042148)
0.3 0.8 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.2 0.6 GO:0065001 specification of axis polarity(GO:0065001)
0.2 0.9 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.2 0.7 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.2 0.8 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.2 2.8 GO:0060046 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.7 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.6 GO:0006740 NADPH regeneration(GO:0006740)
0.1 2.2 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.0 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.1 0.4 GO:0050787 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.1 0.4 GO:0042420 octopamine biosynthetic process(GO:0006589) dopamine catabolic process(GO:0042420) norepinephrine biosynthetic process(GO:0042421) octopamine metabolic process(GO:0046333)
0.1 0.3 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.1 1.0 GO:0044857 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 0.3 GO:0006824 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.1 0.8 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 1.1 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.3 GO:1900182 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 0.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 1.8 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 2.0 GO:0001843 neural tube closure(GO:0001843)
0.1 0.4 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.1 1.1 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.4 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.5 GO:0040016 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) embryonic cleavage(GO:0040016)
0.1 0.3 GO:1901207 regulation of heart looping(GO:1901207)
0.1 0.4 GO:0070254 mucus secretion(GO:0070254)
0.1 0.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.4 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.3 GO:0032530 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.1 0.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.3 GO:1990592 IRE1-mediated unfolded protein response(GO:0036498) negative regulation of response to endoplasmic reticulum stress(GO:1903573) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.6 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 2.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.5 GO:0003211 cardiac ventricle formation(GO:0003211)
0.1 0.3 GO:0051972 regulation of telomerase activity(GO:0051972)
0.1 0.3 GO:0051031 tRNA transport(GO:0051031)
0.0 0.2 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.0 0.2 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.0 1.4 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 1.7 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 0.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.2 GO:1904396 regulation of neuromuscular junction development(GO:1904396)
0.0 0.1 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.3 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 1.2 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0008594 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.4 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.7 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 1.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.2 GO:0046247 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.4 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.7 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.8 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0014743 regulation of muscle hypertrophy(GO:0014743)
0.0 0.2 GO:0042987 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.0 0.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.2 GO:0043330 response to exogenous dsRNA(GO:0043330)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0070874 negative regulation of peptidyl-serine phosphorylation(GO:0033137) negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.2 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.4 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.5 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 1.7 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.0 GO:0019264 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
0.0 0.4 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.3 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) response to interleukin-15(GO:0070672) cellular response to interleukin-15(GO:0071350)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0061702 inflammasome complex(GO:0061702)
0.2 1.0 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.3 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.6 GO:0032797 SMN complex(GO:0032797)
0.1 0.9 GO:0030315 T-tubule(GO:0030315)
0.1 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.1 2.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 1.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.6 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.7 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0030428 cell septum(GO:0030428)
0.0 0.6 GO:0031430 M band(GO:0031430)
0.0 1.2 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 1.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 2.3 GO:0000786 nucleosome(GO:0000786)
0.0 1.0 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 0.2 GO:0016528 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.8 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.3 GO:0000784 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0 0.4 GO:0043186 P granule(GO:0043186)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 0.7 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.2 0.7 GO:0008397 sterol 12-alpha-hydroxylase activity(GO:0008397)
0.2 0.8 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.2 0.6 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 0.5 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.2 1.6 GO:0005522 profilin binding(GO:0005522)
0.2 0.6 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.6 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.4 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.5 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.8 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.8 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 1.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 1.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 2.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.3 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.8 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.5 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 0.2 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.1 0.4 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.4 GO:0004104 cholinesterase activity(GO:0004104)
0.1 1.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.0 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
0.1 0.3 GO:0031005 filamin binding(GO:0031005)
0.1 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.6 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 2.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.3 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.7 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.6 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.6 GO:0031729 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 1.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 1.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.3 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.2 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.2 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.1 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.0 0.4 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 0.2 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.2 GO:0030250 calcium sensitive guanylate cyclase activator activity(GO:0008048) cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.0 0.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.3 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.7 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 1.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.0 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 0.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism