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PRJNA207719: Tissue specific transcriptome profiling

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Results for sox7

Z-value: 0.54

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Transcription factors associated with sox7

Gene Symbol Gene ID Gene Info
sox7
ENSDARG00000030125 SRY-box transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox7dr11_v1_chr20_+_19066858_190668580.741.5e-01Click!

Activity profile of sox7 motif

Sorted Z-values of sox7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_29191152 0.54 ENSDART00000132702
pvalb7
parvalbumin 7
chr22_-_29204960 0.51 ENSDART00000131386
pvalb7
parvalbumin 7
chr15_-_23647078 0.50 ENSDART00000059366
ckmb
creatine kinase, muscle b
chr2_-_24996441 0.39 ENSDART00000144795
slc35g2a
solute carrier family 35, member G2a
chr22_-_29205327 0.37 ENSDART00000183161
ENSDART00000189515
pvalb7
parvalbumin 7
chr20_+_50956369 0.31 ENSDART00000170854
gphnb
gephyrin b
chr16_+_10777116 0.27 ENSDART00000190902
atp1a3b
ATPase Na+/K+ transporting subunit alpha 3b
chr25_-_22639133 0.25 ENSDART00000073583
islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr16_+_46111849 0.24 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr1_-_470812 0.23 ENSDART00000192527
zgc:92518
zgc:92518
chr8_+_23174137 0.23 ENSDART00000189470
dnajc5aa
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr20_-_25709247 0.21 ENSDART00000146711
si:dkeyp-117h8.2
si:dkeyp-117h8.2
chr13_+_24829996 0.21 ENSDART00000147194
si:ch211-223p8.8
si:ch211-223p8.8
chr22_-_12862415 0.18 ENSDART00000145156
ENSDART00000137280
glsa
glutaminase a
chr17_-_26537928 0.18 ENSDART00000155692
ENSDART00000122366
ccser2a
coiled-coil serine-rich protein 2a
chr14_+_6546516 0.16 ENSDART00000097214
adam19b
ADAM metallopeptidase domain 19b
chr11_+_10541258 0.16 ENSDART00000132365
b3gnt5a
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr17_-_22010668 0.16 ENSDART00000031998
slc22a7b.1
solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 1
chr10_-_7913591 0.16 ENSDART00000139661
slc35e4
solute carrier family 35, member E4
chr15_-_21692630 0.15 ENSDART00000039865
sdhdb
succinate dehydrogenase complex, subunit D, integral membrane protein b
chr17_+_15534815 0.14 ENSDART00000159426
marcksb
myristoylated alanine-rich protein kinase C substrate b
chr12_+_26621906 0.14 ENSDART00000158440
ENSDART00000046959
arhgap12b
Rho GTPase activating protein 12b
chr14_-_30490465 0.14 ENSDART00000173107
micu3b
mitochondrial calcium uptake family, member 3b
chr11_-_35970966 0.14 ENSDART00000188805
itpr1b
inositol 1,4,5-trisphosphate receptor, type 1b
chr14_-_6365223 0.13 ENSDART00000167446
slc44a1b
solute carrier family 44 (choline transporter), member 1b
chr18_-_39200557 0.13 ENSDART00000132367
ENSDART00000183672
si:ch211-235f12.2
mapk6
si:ch211-235f12.2
mitogen-activated protein kinase 6
chr19_-_42462491 0.13 ENSDART00000131715
psmb4
proteasome subunit beta 4
chr16_+_27345383 0.13 ENSDART00000078250
ENSDART00000162857
nr4a3
nuclear receptor subfamily 4, group A, member 3
chr10_-_23379146 0.12 ENSDART00000056369
cadm2a
cell adhesion molecule 2a
chr25_-_7999756 0.11 ENSDART00000159908
camk1db
calcium/calmodulin-dependent protein kinase 1Db
chr5_-_69923241 0.10 ENSDART00000187389
fktn
fukutin
chr5_+_34982318 0.10 ENSDART00000160504
ankra2
ankyrin repeat, family A (RFXANK-like), 2
chr22_-_26558166 0.10 ENSDART00000111125
glis2a
GLIS family zinc finger 2a
chr21_+_31811202 0.09 ENSDART00000189846
si:ch211-12m10.1
si:ch211-12m10.1
chr19_-_11031145 0.09 ENSDART00000151375
ENSDART00000027598
ENSDART00000137865
ENSDART00000188025
tpm3
tropomyosin 3
chr12_+_30109698 0.09 ENSDART00000042572
ENSDART00000153025
ablim1b
actin binding LIM protein 1b
chr9_-_23033818 0.09 ENSDART00000022392
rnd3b
Rho family GTPase 3b
chr12_+_4114401 0.09 ENSDART00000025912
si:dkey-32n7.4
si:dkey-32n7.4
chr19_+_5480327 0.08 ENSDART00000148794
jupb
junction plakoglobin b
chr1_+_36674584 0.08 ENSDART00000186772
ENSDART00000192274
ednraa
endothelin receptor type Aa
chr11_+_44356707 0.08 ENSDART00000165219
srsf7b
serine/arginine-rich splicing factor 7b
chr11_-_3613558 0.08 ENSDART00000163578
dnajc16l
DnaJ (Hsp40) homolog, subfamily C, member 16 like
chr11_+_44356504 0.07 ENSDART00000160678
srsf7b
serine/arginine-rich splicing factor 7b
chr8_+_35664152 0.07 ENSDART00000144520
si:dkeyp-14d3.1
si:dkeyp-14d3.1
chr2_-_16986894 0.06 ENSDART00000145720
clcn2a
chloride channel, voltage-sensitive 2a
chr1_+_6206950 0.06 ENSDART00000146473
retreg2
reticulophagy regulator family member 2
chr3_+_52737565 0.06 ENSDART00000108639
gmip
GEM interacting protein
chr24_-_20652473 0.05 ENSDART00000179984
nktr
natural killer cell triggering receptor
chr5_-_67911111 0.05 ENSDART00000051833
gsx1
GS homeobox 1
chr7_+_41421998 0.05 ENSDART00000083967
chpf2
chondroitin polymerizing factor 2
chr20_-_4766645 0.05 ENSDART00000147071
ENSDART00000152398
ak7a
adenylate kinase 7a
chr22_+_2239254 0.04 ENSDART00000131396
ENSDART00000135320
znf1144
zinc finger protein 1144
chr15_-_35252522 0.04 ENSDART00000144153
ENSDART00000059195
mff
mitochondrial fission factor
chr12_-_4540564 0.04 ENSDART00000106566
CABZ01030107.1

chr7_-_35083184 0.04 ENSDART00000100253
ENSDART00000135250
ENSDART00000173511
agrp
agouti related neuropeptide
chr1_-_49649122 0.03 ENSDART00000134399
slkb
STE20-like kinase b
chr3_-_51142942 0.03 ENSDART00000160789
si:ch211-148f13.1
si:ch211-148f13.1
chr18_+_15876385 0.03 ENSDART00000142527
eea1
early endosome antigen 1
chr13_+_10799380 0.03 ENSDART00000126427
lrpprc
leucine-rich pentatricopeptide repeat containing
chr9_+_38369872 0.02 ENSDART00000193914
plcd4b
phospholipase C, delta 4b
chr19_+_10860485 0.02 ENSDART00000169962
si:ch73-347e22.4
si:ch73-347e22.4
chr24_+_35787629 0.02 ENSDART00000136721
si:dkeyp-7a3.1
si:dkeyp-7a3.1
chr16_+_40024883 0.02 ENSDART00000110100
hint3
histidine triad nucleotide binding protein 3
chr8_-_20291922 0.02 ENSDART00000148304
myo1f
myosin IF
chr23_+_21261313 0.01 ENSDART00000104268
ENSDART00000159046
emc1
ER membrane protein complex subunit 1
chr4_-_71311438 0.01 ENSDART00000168021
si:dkeyp-123a12.2
si:dkeyp-123a12.2
chr7_-_4107423 0.01 ENSDART00000172971
zgc:55733
zgc:55733
chr5_-_3960161 0.01 ENSDART00000111453
myo19
myosin XIX
chr8_+_2787042 0.00 ENSDART00000155275
sh3glb2a
SH3-domain GRB2-like endophilin B2a
chr14_+_1124409 0.00 ENSDART00000190043
ENSDART00000106708
ENSDART00000160246
sec24b
SEC24 homolog B, COPII coat complex component
chr22_-_26852516 0.00 ENSDART00000005829
gde1
glycerophosphodiester phosphodiesterase 1
chr22_+_29204885 0.00 ENSDART00000133409
ENSDART00000059820
ncf4
neutrophil cytosolic factor 4
chr13_+_43650632 0.00 ENSDART00000141024
zfyve21
zinc finger, FYVE domain containing 21

Network of associatons between targets according to the STRING database.

First level regulatory network of sox7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0018315 establishment of synaptic specificity at neuromuscular junction(GO:0007529) molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.5 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.2 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.0 0.3 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.1 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.2 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.5 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)