PRJNA207719: Tissue specific transcriptome profiling


Results for sox21b

Z-value: 1.79

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Transcription factors associated with sox21b

Gene Symbol Gene ID Gene Info
ENSDARG00000008540 SRY-box transcription factor 21b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot

Activity profile of sox21b motif

Sorted Z-values of sox21b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_37582872 2.92 ENSDART00000169331
adhesion G protein-coupled receptor B1a
chr2_-_54387550 2.28 ENSDART00000097388
N-ethylmaleimide-sensitive factor attachment protein, gamma b
chr14_+_49135264 2.27 ENSDART00000084119
chr4_+_75200467 2.16 ENSDART00000122593

chr15_+_28685625 2.11 ENSDART00000188797
neuro-oncological ventral antigen 2
chr21_-_42007213 2.02 ENSDART00000188804
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr13_-_24448278 1.93 ENSDART00000057584
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr8_-_49431939 1.87 ENSDART00000011453
synaptophysin b
chr19_-_7450796 1.83 ENSDART00000104750
MLLT11, transcription factor 7 cofactor
chr25_+_4837915 1.68 ENSDART00000168016
guanine nucleotide binding protein (G protein), beta 5a
chr21_-_42007482 1.66 ENSDART00000075740
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr16_-_42390441 1.59 ENSDART00000148475
chondroitin sulfate proteoglycan 5a
chr7_+_73630751 1.51 ENSDART00000159745
chr5_-_13167097 1.50 ENSDART00000149700
mitogen-activated protein kinase 1
chr15_+_28685892 1.46 ENSDART00000155815
neuro-oncological ventral antigen 2
chr19_-_28360033 1.38 ENSDART00000186994
chr8_-_52473054 1.35 ENSDART00000193658
phytanoyl-CoA 2-hydroxylase interacting protein
chr3_-_50127668 1.29 ENSDART00000062116
claudin k
chr5_+_64732036 1.27 ENSDART00000073950
olfactomedin 1a
chr11_-_1509773 1.21 ENSDART00000050762
phosphatase and actin regulator 3b
chr16_-_44399335 1.19 ENSDART00000165058
regulating synaptic membrane exocytosis 2a
chr16_+_37470717 1.16 ENSDART00000112003
adhesion G protein-coupled receptor B1a
chr18_+_13837746 1.14 ENSDART00000169552
cadherin 13, H-cadherin (heart)
chr6_-_48473395 1.14 ENSDART00000185096
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr9_+_17971935 1.13 ENSDART00000149736
A kinase (PRKA) anchor protein 11
chr8_-_1838315 1.13 ENSDART00000114476
phosphatidylinositol 4-kinase, catalytic, alpha b
chr20_-_34801181 1.10 ENSDART00000048375
stathmin-like 4
chr8_+_49149907 1.08 ENSDART00000138746
syntaphilin a
chr25_-_12203952 1.08 ENSDART00000158204
neurotrophic tyrosine kinase, receptor, type 3a
chr8_-_31403938 1.05 ENSDART00000159168
NIM1 serine/threonine protein kinase
chr5_+_66353750 1.03 ENSDART00000143410
chr25_-_19433244 1.01 ENSDART00000154778
microtubule-associated protein 1Ab
chr19_-_41069573 1.00 ENSDART00000111982
sarcoglycan, epsilon
chr17_-_36936856 1.00 ENSDART00000010274
dihydropyrimidinase-like 5a
chr10_-_34871737 0.98 ENSDART00000138755
doublecortin-like kinase 1a
chr12_-_19102736 0.98 ENSDART00000180364
cold shock domain containing C2, RNA binding a
chr5_+_27137473 0.96 ENSDART00000181833
unc-5 netrin receptor Db
chr9_-_6661657 0.96 ENSDART00000133178
POU class 3 homeobox 3a
chr18_-_8313686 0.95 ENSDART00000182187
mitogen-activated protein kinase 8 interacting protein 2
chr25_+_29662411 0.93 ENSDART00000077445
Pim-3 proto-oncogene, serine/threonine kinase
chr17_-_44249720 0.91 ENSDART00000156648
orthodenticle homeobox 2b
chr19_+_2279051 0.89 ENSDART00000182103
integrin, beta 8
chr3_-_21037840 0.87 ENSDART00000002393
RUN domain containing 3Aa
chr8_+_25913787 0.86 ENSDART00000190257
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3H
chr6_-_35310224 0.85 ENSDART00000148997
nitric oxide synthase 1 (neuronal) adaptor protein a
chr12_-_37734973 0.84 ENSDART00000140353
sidekick cell adhesion molecule 2b
chr14_-_2217285 0.83 ENSDART00000157949
protocadherin 2 alpha b2
protocadherin 2 alpha b2
chr6_-_46403475 0.82 ENSDART00000154148
calcium/calmodulin-dependent protein kinase Ia
chr9_+_13733468 0.82 ENSDART00000165954
abl-interactor 2a
chr14_-_2327825 0.81 ENSDART00000180328
protocadherin 2 alpha b 8
protocadherin 2 alpha a 1
chr19_-_867071 0.80 ENSDART00000122257
eomesodermin homolog a
chr2_-_32356539 0.80 ENSDART00000169316
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a
chr23_-_7125494 0.79 ENSDART00000111929
solute carrier organic anion transporter family, member 4A1
chr19_-_38872650 0.78 ENSDART00000146641
adhesion G protein-coupled receptor B2
chr7_-_71434298 0.78 ENSDART00000180507
leucine-rich repeat LGI family, member 2a
chr17_+_44780166 0.77 ENSDART00000156260
transmembrane protein 63C
chr1_+_41666611 0.75 ENSDART00000145789
F-box protein 41
chr20_-_45661049 0.72 ENSDART00000124582
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr17_-_8656155 0.70 ENSDART00000148990
C-terminal binding protein 2a
chr24_-_24271629 0.70 ENSDART00000135060
ribosomal protein S6 kinase, polypeptide 3b
chr13_-_39399967 0.70 ENSDART00000190791
solute carrier family 35, member F3b
chr14_+_34966598 0.69 ENSDART00000004550
ring finger protein 145a
chr2_+_31833997 0.69 ENSDART00000066788
ependymin related 1
chr1_-_625875 0.68 ENSDART00000167331
amyloid beta (A4) precursor protein a
chr18_+_29950233 0.68 ENSDART00000146431
ATM interactor
chr19_+_1835940 0.67 ENSDART00000167372
protein tyrosine kinase 2aa
chr11_-_25733910 0.65 ENSDART00000171935
bromodomain and PHD finger containing, 3a
chr22_+_12798569 0.63 ENSDART00000005720
signal transducer and activator of transcription 1a
chr4_+_5506952 0.62 ENSDART00000032857
mitogen-activated protein kinase 11
chr14_+_35405518 0.62 ENSDART00000171565
zinc finger and BTB domain containing 3
chr22_-_1245226 0.62 ENSDART00000161292
adenosine monophosphate deaminase 2a
chr17_-_277046 0.61 ENSDART00000182587

chr12_-_15002563 0.61 ENSDART00000108852
protein kinase, membrane associated tyrosine/threonine 1
chr7_+_72012397 0.60 ENSDART00000011303
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2
chr12_+_41991635 0.60 ENSDART00000186161
transcription elongation regulator 1 like
chr18_+_924949 0.58 ENSDART00000170888
pyruvate kinase M1/2a
chr11_-_42980535 0.57 ENSDART00000181160

chr19_-_42045372 0.57 ENSDART00000144275
trio Rho guanine nucleotide exchange factor a
chr5_-_67895656 0.56 ENSDART00000158917
abhydrolase domain containing 10a
chr3_-_60142530 0.56 ENSDART00000153247
chr11_+_36231248 0.55 ENSDART00000131104
chr5_-_33825465 0.55 ENSDART00000110645
DAB2 interacting protein b
chr16_-_40841363 0.54 ENSDART00000163380
chr23_-_42810664 0.54 ENSDART00000102328
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr14_+_44545092 0.54 ENSDART00000175454
leucine rich repeat and Ig domain containing 2a
chr24_+_8904741 0.53 ENSDART00000140924
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr23_+_6795709 0.52 ENSDART00000149136
chr17_+_15882533 0.52 ENSDART00000164124
gamma-aminobutyric acid (GABA) A receptor, rho 2a
chr7_+_26466826 0.52 ENSDART00000058908
mannose-P-dolichol utilization defect 1b
chr23_+_6795531 0.51 ENSDART00000092131
chr14_+_28281744 0.51 ENSDART00000173292
midline 2
chr3_-_34296361 0.50 ENSDART00000181485
trinucleotide repeat containing 6C1
chr22_-_38480186 0.50 ENSDART00000171704
heme-binding protein soul4
chr7_-_51603276 0.49 ENSDART00000174054
NHS-like 2
chr9_-_27805801 0.49 ENSDART00000140608
chr5_+_21144269 0.49 ENSDART00000028087
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr14_-_4273396 0.49 ENSDART00000127318
FERM and PDZ domain containing 1b
chr5_-_64865521 0.49 ENSDART00000043397
chr18_+_9493720 0.47 ENSDART00000053125
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr1_+_34295925 0.46 ENSDART00000075584
potassium channel tetramerisation domain containing 12.2
chr10_+_35275965 0.46 ENSDART00000077404
P450 (cytochrome) oxidoreductase a
chr1_+_26445615 0.45 ENSDART00000180810
GTPase activating protein (SH3 domain) binding protein 2
chr17_+_24320861 0.43 ENSDART00000179858
orthodenticle homeobox 1
chr23_+_21482571 0.42 ENSDART00000187368
chr13_-_41546779 0.42 ENSDART00000163331
protocadherin-related 15a
chr8_-_13184989 0.42 ENSDART00000135738
chr9_+_34641237 0.42 ENSDART00000133996
short stature homeobox
chr23_+_5565261 0.41 ENSDART00000059307
sphingomyelin phosphodiesterase 2a, neutral membrane (neutral sphingomyelinase)
chr7_-_40122139 0.41 ENSDART00000173982
chr22_+_33131891 0.41 ENSDART00000126885
dystroglycan 1
chr5_+_66353589 0.40 ENSDART00000138246
chr15_-_2184638 0.40 ENSDART00000135460
short stature homeobox 2
chr5_+_20693724 0.40 ENSDART00000141368
chr5_-_31035198 0.39 ENSDART00000086534
cytochrome b5 domain containing 2
chr5_-_28767573 0.39 ENSDART00000158299
Tnf receptor-associated factor 2a
chr16_-_37372613 0.38 ENSDART00000124090
chr21_-_37951819 0.38 ENSDART00000139549
chr7_-_35708450 0.37 ENSDART00000193886
iroquois homeobox 5a
chr2_-_31791633 0.36 ENSDART00000180662
reticulophagy regulator 1
chr23_-_27050083 0.36 ENSDART00000142324
chr7_+_828289 0.35 ENSDART00000173796
chr23_-_21946603 0.35 ENSDART00000148120
eph receptor B2a
chr23_+_40951443 0.35 ENSDART00000115161
RALBP1 associated Eps domain containing 2
chr13_+_50151407 0.35 ENSDART00000031858
G protein-coupled receptor 137Ba
chr6_+_52235441 0.34 ENSDART00000056319
cytochrome c oxidase subunit VIc
chr17_-_22010668 0.34 ENSDART00000031998
solute carrier family 22 (organic anion transporter), member 7b, tandem duplicate 1
chr21_+_39423974 0.34 ENSDART00000031470
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b
chr8_-_50981175 0.34 ENSDART00000004065
chr17_+_3993772 0.33 ENSDART00000170822
thioredoxin-related transmembrane protein 4
chr13_+_23132666 0.33 ENSDART00000164639
sorbin and SH3 domain containing 1
chr8_+_2487883 0.33 ENSDART00000101841
dynein, light chain, LC8-type 1
chr10_+_43188678 0.32 ENSDART00000012522
versican b
chr17_+_23146976 0.32 ENSDART00000114212
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr4_+_72742212 0.32 ENSDART00000171021
RAB3A interacting protein (rabin3)
chr11_-_26362294 0.31 ENSDART00000184654
forkhead box J3
chr21_+_27278120 0.31 ENSDART00000193882
chr18_-_46882056 0.31 ENSDART00000108574
GRAM domain containing 1Bb
chr21_+_26389391 0.31 ENSDART00000077197
thymosin, beta
chr19_+_32401278 0.30 ENSDART00000184353
ataxin 1a
chr13_-_11035420 0.30 ENSDART00000108709
centrosomal protein 170Aa
chr19_+_30450125 0.29 ENSDART00000073704
chr17_+_19630272 0.29 ENSDART00000104895
regulator of G protein signaling 7a
chr7_-_24390879 0.28 ENSDART00000036680
prostaglandin reductase 1
chr17_+_28533102 0.28 ENSDART00000156218
MAM domain containing glycosylphosphatidylinositol anchor 2a
chr8_+_2487250 0.28 ENSDART00000081325
dynein, light chain, LC8-type 1
chr5_+_54555567 0.28 ENSDART00000171159
anaphase promoting complex subunit 2
chr1_+_26444986 0.27 ENSDART00000046376
GTPase activating protein (SH3 domain) binding protein 2
chr12_+_15002757 0.27 ENSDART00000135036
myosin light chain, phosphorylatable, fast skeletal muscle b
chr12_+_25097754 0.27 ENSDART00000050070
phosphatidylinositol glycan anchor biosynthesis, class F
chr13_-_19799824 0.27 ENSDART00000058032
family with sequence similarity 204, member A
chr11_-_34522249 0.26 ENSDART00000158616
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr6_+_41099787 0.26 ENSDART00000186884
FK506 binding protein 5
chr21_-_29117670 0.26 ENSDART00000124327
hepatitis A virus cellular receptor 2
chr3_-_30488063 0.26 ENSDART00000055393
mediator complex subunit 25
chr17_+_2214283 0.26 ENSDART00000189187
p21 protein (Cdc42/Rac)-activated kinase 6a
chr22_+_17399124 0.26 ENSDART00000145769
RAB GTPase activating protein 1-like
chr6_-_57539141 0.26 ENSDART00000156967
itchy E3 ubiquitin protein ligase a
chr12_+_16967715 0.25 ENSDART00000138174
solute carrier family 16, member 12b
chr11_-_44979281 0.25 ENSDART00000190972
LIM-domain binding 1b
chr4_+_5333988 0.25 ENSDART00000129398
APEX nuclease (multifunctional DNA repair enzyme) 1
chr11_+_41981959 0.24 ENSDART00000055707
hairy and enhancer of split-related 15, tandem duplicate 1
chr5_+_13521081 0.24 ENSDART00000171975
chr5_-_55623443 0.24 ENSDART00000005671
heterogeneous nuclear ribonucleoprotein K, like
chr10_-_26430168 0.24 ENSDART00000128894
dachsous cadherin-related 1b
chr12_+_499881 0.24 ENSDART00000167527
myosin phosphatase Rho interacting protein
chr5_-_65691512 0.24 ENSDART00000189255
notch 1b
chr1_+_11822 0.23 ENSDART00000166393
centrosomal protein 97
chr2_+_24374305 0.23 ENSDART00000022379
nuclear receptor subfamily 2, group F, member 6a
chr6_-_52234796 0.23 ENSDART00000001803
translocase of outer mitochondrial membrane 34
chr10_-_15963903 0.23 ENSDART00000142357
chr10_-_8197049 0.23 ENSDART00000129467
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr16_-_38067952 0.22 ENSDART00000114266
pleckstrin homology domain containing, family O member 1b
chr16_-_8342749 0.22 ENSDART00000028108
dopa decarboxylase
chr17_+_8175998 0.21 ENSDART00000131200
myc target 1b
chr15_-_47338769 0.21 ENSDART00000164983
anaphase promoting complex subunit 15
chr9_-_27805644 0.20 ENSDART00000192431
chr9_+_9112943 0.20 ENSDART00000083033
salt-inducible kinase 1
chr20_-_7069612 0.20 ENSDART00000040793
sirtuin 5
chr8_+_16726386 0.20 ENSDART00000144621
small integral membrane protein 15
chr6_-_29086473 0.20 ENSDART00000124947
ecotropic viral integration site 5b
chr8_+_18010568 0.20 ENSDART00000121984
single stranded DNA binding protein 3b
chr13_-_43637371 0.20 ENSDART00000127930
family with sequence similarity 160, member B1
chr2_-_24981356 0.19 ENSDART00000111212
NCK adaptor protein 1a
chr7_+_24023653 0.19 ENSDART00000141165
TERF1 (TRF1)-interacting nuclear factor 2
chr2_-_1548330 0.19 ENSDART00000082155
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr14_-_49896795 0.19 ENSDART00000168142
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), like
chr21_-_4250682 0.19 ENSDART00000099389
DNL-type zinc finger
chr23_-_35821521 0.19 ENSDART00000103169
nuclear receptor subfamily 1, group D, member 4a
chr18_+_6039141 0.19 ENSDART00000138972
chr25_-_28668776 0.18 ENSDART00000126490
formin binding protein 4
chr1_-_46650022 0.18 ENSDART00000148759
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr21_+_21263988 0.18 ENSDART00000089651
coiled-coil domain containing 61
chr9_-_23118350 0.18 ENSDART00000020884
LY6/PLAUR domain containing 6
chr8_-_13678415 0.17 ENSDART00000134153
chr25_+_36046287 0.17 ENSDART00000185324
chr20_-_26420939 0.17 ENSDART00000110883
A kinase (PRKA) anchor protein 12b
chr12_+_46869271 0.17 ENSDART00000166560
4-hydroxyphenylpyruvate dioxygenase-like
chr20_-_894374 0.16 ENSDART00000104725
sorting nexin 14
chr1_+_19764995 0.16 ENSDART00000138276
chr6_-_52235118 0.16 ENSDART00000191243
translocase of outer mitochondrial membrane 34

Network of associatons between targets according to the STRING database.

First level regulatory network of sox21b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 GO:0070208 protein heterotrimerization(GO:0070208)
0.4 1.8 GO:0090199 regulation of mitochondrial membrane potential(GO:0051881) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.3 0.8 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.2 1.1 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.2 0.7 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.2 1.6 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.1 0.9 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.1 1.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.1 1.3 GO:1902868 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.1 5.4 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 0.3 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.1 1.0 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.5 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.6 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.7 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.1 0.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.3 GO:0021611 facial nerve formation(GO:0021611)
0.1 1.9 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 1.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.3 GO:0051012 reelin-mediated signaling pathway(GO:0038026) microtubule sliding(GO:0051012)
0.1 0.2 GO:1903673 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.1 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.2 GO:0090231 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 1.1 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.1 0.5 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.4 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.2 GO:1904969 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.1 1.0 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.1 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 1.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.7 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.4 GO:0033292 T-tubule organization(GO:0033292)
0.1 1.4 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.6 GO:0060337 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0010312 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.0 0.7 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.6 GO:0032264 IMP salvage(GO:0032264)
0.0 2.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 3.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:0061709 reticulophagy(GO:0061709)
0.0 0.2 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 1.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.5 GO:0006003 fructose metabolic process(GO:0006000) fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.5 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0034163 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.2 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.0 0.3 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.9 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.2 GO:1901739 regulation of myoblast fusion(GO:1901739)
0.0 1.3 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.2 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.2 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 1.3 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 0.2 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.8 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.3 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.2 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 1.0 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.2 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 1.1 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.5 GO:0021986 habenula development(GO:0021986)
0.0 0.6 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.8 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.1 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.2 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.4 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.7 GO:0006096 glycolytic process(GO:0006096)
0.0 0.2 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 1.4 GO:0016011 dystroglycan complex(GO:0016011)
0.1 4.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.3 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 0.3 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.2 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.7 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 4.1 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 1.9 GO:0031201 SNARE complex(GO:0031201)
0.0 1.4 GO:0016342 catenin complex(GO:0016342)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.9 GO:0008305 integrin complex(GO:0008305)
0.0 0.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.0 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.8 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.3 3.7 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.2 1.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.2 1.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.9 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.5 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.5 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 1.7 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 1.0 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 1.1 GO:0038191 neuropilin binding(GO:0038191)
0.1 2.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.1 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 0.3 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 2.1 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.7 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.2 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1 0.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.7 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 1.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.0 1.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.3 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.6 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 1.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.4 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0003785 actin monomer binding(GO:0003785)
0.0 4.9 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.4 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 2.1 GO:0015293 symporter activity(GO:0015293)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 0.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 0.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.2 3.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 0.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 0.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 0.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 1.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.3 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions