Project
PRJNA207719: Tissue specific transcriptome profiling
Navigation
Downloads
Results for sox21b
Z-value: 1.79
Motif logo
Transcription factors associated with sox21b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| sox21b | dr11_v1_chr9_+_53276356_53276356 | 0.96 | 8.4e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_+_37582872 Show fit | 2.92 |
ENSDART00000169331
|
adhesion G protein-coupled receptor B1a |
|
| chr2_-_54387550 Show fit | 2.28 |
ENSDART00000097388
|
N-ethylmaleimide-sensitive factor attachment protein, gamma b |
|
| chr14_+_49135264 Show fit | 2.27 |
ENSDART00000084119
|
si:ch1073-44g3.1 |
|
| chr4_+_75200467 Show fit | 2.16 |
ENSDART00000122593
|
|
|
| chr15_+_28685625 Show fit | 2.11 |
ENSDART00000188797
ENSDART00000166036 |
neuro-oncological ventral antigen 2 |
|
| chr21_-_42007213 Show fit | 2.02 |
ENSDART00000188804
ENSDART00000092821 ENSDART00000165743 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 |
|
| chr13_-_24448278 Show fit | 1.93 |
ENSDART00000057584
|
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
|
| chr8_-_49431939 Show fit | 1.87 |
ENSDART00000011453
ENSDART00000088240 ENSDART00000114173 |
synaptophysin b |
|
| chr19_-_7450796 Show fit | 1.83 |
ENSDART00000104750
|
MLLT11, transcription factor 7 cofactor |
|
| chr25_+_4837915 Show fit | 1.68 |
ENSDART00000168016
|
guanine nucleotide binding protein (G protein), beta 5a |
Network of associatons between targets according to the STRING database.
First level regulatory network of sox21b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.4 | GO:0016525 | negative regulation of angiogenesis(GO:0016525) |
| 0.7 | 3.7 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.0 | 3.6 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 2.1 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.1 | 1.9 | GO:0048168 | regulation of neuronal synaptic plasticity(GO:0048168) |
| 0.4 | 1.8 | GO:0090199 | regulation of mitochondrial membrane potential(GO:0051881) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
| 0.2 | 1.6 | GO:0099550 | trans-synaptic signalling, modulating synaptic transmission(GO:0099550) |
| 0.1 | 1.5 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.1 | 1.4 | GO:0007634 | optokinetic behavior(GO:0007634) |
| 0.1 | 1.3 | GO:1902868 | positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.2 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.0 | 4.1 | GO:0014069 | postsynaptic density(GO:0014069) |
| 0.0 | 1.9 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 1.9 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 1.6 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.2 | 1.4 | GO:0016011 | dystroglycan complex(GO:0016011) |
| 0.0 | 1.4 | GO:0016342 | catenin complex(GO:0016342) |
| 0.0 | 1.2 | GO:0048788 | cytoskeleton of presynaptic active zone(GO:0048788) |
| 0.0 | 0.9 | GO:0008305 | integrin complex(GO:0008305) |
| 0.0 | 0.8 | GO:0030175 | filopodium(GO:0030175) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.9 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.3 | 3.7 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851) |
| 0.5 | 3.0 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
| 0.1 | 2.9 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 2.1 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.0 | 2.1 | GO:0015293 | symporter activity(GO:0015293) |
| 0.1 | 1.7 | GO:0031682 | G-protein gamma-subunit binding(GO:0031682) |
| 0.0 | 1.4 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.0 | 1.3 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.0 | 1.2 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.5 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 1.3 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.1 | 0.9 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 0.9 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 0.6 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 0.5 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.1 | 0.4 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.0 | 0.3 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.0 | 0.3 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.3 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.7 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 1.9 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.3 | 1.5 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.0 | 1.1 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.9 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 0.8 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.1 | 0.6 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |
| 0.1 | 0.6 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.0 | 0.6 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.1 | 0.5 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |