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PRJNA207719: Tissue specific transcriptome profiling

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Results for sox10

Z-value: 1.41

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Transcription factors associated with sox10

Gene Symbol Gene ID Gene Info
ENSDARG00000077467 SRY-box transcription factor 10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox10dr11_v1_chr3_+_1492174_1492174-0.856.6e-02Click!

Activity profile of sox10 motif

Sorted Z-values of sox10 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_3629201 1.62 ENSDART00000136577
ENSDART00000132121
inter-alpha-trypsin inhibitor heavy chain 3a
chr1_-_19845378 1.16 ENSDART00000139314
ENSDART00000132958
ENSDART00000147502
glyoxylate reductase/hydroxypyruvate reductase b
chr2_-_39017838 1.16 ENSDART00000048838
retinol binding protein 2b, cellular
chr20_-_25518488 0.97 ENSDART00000186993
cytochrome P450, family 2, subfamily N, polypeptide 13
chr16_+_26732086 0.95 ENSDART00000138496
RAD54 homolog B (S. cerevisiae)
chr21_+_20771082 0.85 ENSDART00000079732
3-oxoacid CoA transferase 1b
chr15_-_108414 0.83 ENSDART00000170044
apolipoprotein A-Ib
chr16_-_45917322 0.82 ENSDART00000060822
antifreeze protein type IV
chr16_-_26731928 0.82 ENSDART00000135860
ring finger protein 41, like
chr15_-_32365940 0.82 ENSDART00000155371
complement component 4
chr8_-_50147948 0.81 ENSDART00000149010
haptoglobin
chr23_+_36144487 0.80 ENSDART00000082473
homeobox C3a
chr1_-_33645967 0.78 ENSDART00000192758
claudin g
chr22_-_23591493 0.77 ENSDART00000170266
coagulation factor XIII, B polypeptide
chr21_-_40083432 0.73 ENSDART00000141160
ENSDART00000191195
info solute carrier family 13 (sodium-dependent citrate transporter), member 5a
chr7_-_53117131 0.70 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cadherin 1, type 1, E-cadherin (epithelial)
chr23_+_17981127 0.66 ENSDART00000012571
ENSDART00000145200
chitinase, acidic.6
chr21_-_25756119 0.66 ENSDART00000002341
claudin c
chr23_-_31506854 0.64 ENSDART00000131352
ENSDART00000138625
ENSDART00000133002
EYA transcriptional coactivator and phosphatase 4
chr2_-_43653328 0.64 ENSDART00000037808
integrin, beta 1b.2
chr7_+_39444843 0.63 ENSDART00000143999
ENSDART00000173554
ENSDART00000173698
ENSDART00000173754
ENSDART00000144075
ENSDART00000138192
ENSDART00000145457
ENSDART00000141750
ENSDART00000103056
ENSDART00000142946
ENSDART00000173748
troponin T type 3b (skeletal, fast)
chr14_+_15155684 0.62 ENSDART00000167966
zgc:158852
chr9_+_8396755 0.62 ENSDART00000043067
zgc:171776
chr3_+_15505275 0.62 ENSDART00000141714
nuclear protein 1
chr8_+_39802506 0.61 ENSDART00000018862
HNF1 homeobox a
chr6_-_39313027 0.60 ENSDART00000012644
keratin 4
chr8_-_50482781 0.60 ENSDART00000056361
indoleamine 2,3-dioxygenase 1
chr18_-_6634424 0.57 ENSDART00000062423
ENSDART00000179955
troponin I, skeletal, slow c
chr24_+_10027902 0.57 ENSDART00000175961
ENSDART00000172773
si:ch211-146l10.8
chr22_-_23591340 0.57 ENSDART00000167024
coagulation factor XIII, B polypeptide
chr10_+_9550419 0.56 ENSDART00000064977
si:ch211-243g18.2
chr3_-_18030938 0.55 ENSDART00000013540
si:ch73-141c7.1
chr9_-_18911608 0.54 ENSDART00000138785
si:dkey-239h2.3
chr3_-_34069637 0.53 ENSDART00000151588
immunoglobulin heavy variable 9-1
chr14_+_46313135 0.53 ENSDART00000172902
crystallin, beta A1, like 1
chr20_-_54014539 0.53 ENSDART00000060466
si:dkey-241l7.6
chr14_-_33348221 0.53 ENSDART00000187749
ribosomal protein L39
chr24_-_40700596 0.53 ENSDART00000162635
slow myosin heavy chain 2
chr11_+_12052791 0.51 ENSDART00000158479
si:ch211-156l18.8
chr19_-_27588842 0.50 ENSDART00000121643
si:dkeyp-46h3.2
chr12_-_36045283 0.50 ENSDART00000160646
G protein-coupled receptor, class C, group 5, member C
chr5_+_28849155 0.50 ENSDART00000079090
zgc:174259
chr7_+_35268880 0.49 ENSDART00000182231
dipeptidase 2
chr3_+_3598555 0.49 ENSDART00000191152

chr23_+_36063599 0.49 ENSDART00000103147
homeobox C12a
chr5_+_28848870 0.48 ENSDART00000149563
zgc:174259
chr13_+_46941930 0.47 ENSDART00000056962
F-box protein 5
chr22_-_10541372 0.47 ENSDART00000179708
si:dkey-42i9.4
chr3_+_3545825 0.47 ENSDART00000109060

chr6_-_7020162 0.46 ENSDART00000148982
bridging integrator 1b
chr24_-_26820698 0.46 ENSDART00000147788
fibronectin type III domain containing 3Bb
chr7_+_24814866 0.45 ENSDART00000173581
si:ch211-226l4.6
chr2_-_20052561 0.45 ENSDART00000100133
dihydropyrimidine dehydrogenase b
chr2_-_25140022 0.45 ENSDART00000134543
neutral cholesterol ester hydrolase 1a
chr19_+_9786722 0.44 ENSDART00000138310
calcium channel, voltage-dependent, gamma subunit 6a
chr11_+_29965822 0.44 ENSDART00000127049
interleukin-1 family member A
chr11_-_10659195 0.44 ENSDART00000115255
MCF.2 cell line derived transforming sequence-like 2
chr20_-_40360571 0.43 ENSDART00000144768
sphingomyelin phosphodiesterase, acid-like 3A
chr15_+_22390076 0.43 ENSDART00000183764
OAF homolog a (Drosophila)
chr3_+_56645710 0.43 ENSDART00000193978

chr20_-_43775495 0.42 ENSDART00000100610
ENSDART00000149001
ENSDART00000148809
ENSDART00000100608
matrilin 3a
chr16_+_19029297 0.42 ENSDART00000115263
ENSDART00000114954
Rap guanine nucleotide exchange factor (GEF) 5b
chr9_+_11293830 0.42 ENSDART00000144440
wingless-type MMTV integration site family, member 6b
chr16_-_27566552 0.42 ENSDART00000142102
zgc:153215
chr22_+_1028724 0.42 ENSDART00000149625
si:ch73-352p18.4
chr23_-_10175898 0.42 ENSDART00000146185
keratin 5
chr7_-_6459481 0.42 ENSDART00000173158
zgc:112234
chr19_-_47570672 0.42 ENSDART00000112155
ribonucleotide reductase M2 polypeptide
chr16_+_40560622 0.42 ENSDART00000038294
tumor protein p53 inducible nuclear protein 1
chr14_+_16036139 0.41 ENSDART00000190733
PRELI domain containing 1a
chr6_+_45932276 0.41 ENSDART00000103491
retinol binding protein 7b, cellular
chr20_+_40237441 0.40 ENSDART00000168928
si:ch211-199i15.5
chr5_-_30380593 0.40 ENSDART00000148039
sorting nexin 19a
chr8_-_38201415 0.40 ENSDART00000155189
PDZ and LIM domain 2 (mystique)
chr10_-_35149513 0.40 ENSDART00000063434
ENSDART00000131291
receptor-interacting serine-threonine kinase 4
chr15_+_12429206 0.40 ENSDART00000168997
transmembrane protease, serine 4a
chr25_+_11281970 0.39 ENSDART00000180094
si:dkey-187e18.1
chr15_-_945804 0.39 ENSDART00000063257
arachidonate 5-lipoxygenase b, tandem duplicate 1
chr5_-_41841892 0.39 ENSDART00000167089
si:dkey-65b12.6
chr10_-_25823258 0.39 ENSDART00000064327
finTRIM family, member 54
chr16_-_41762983 0.38 ENSDART00000192936
si:dkey-199f5.8
chr19_-_10730488 0.38 ENSDART00000126033
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3, tandem duplicate 1
chr11_+_42587900 0.38 ENSDART00000167529
ankyrin repeat and SOCS box containing 14a
chr5_-_42894068 0.38 ENSDART00000169606
chemokine (C-X-C motif) ligand 11, duplicate 1
chr7_+_26058772 0.38 ENSDART00000101123
ENSDART00000173893
si:dkey-6n21.13
chr17_-_6599484 0.38 ENSDART00000156927
si:ch211-189e2.2
chr22_-_38274188 0.37 ENSDART00000139420
ENSDART00000015117
ELAV like neuron-specific RNA binding protein 2
chr22_-_17489040 0.37 ENSDART00000141286
si:ch211-197g15.6
chr7_-_71531846 0.37 ENSDART00000111797
alkaline ceramidase 2
chr6_-_23931442 0.37 ENSDART00000160547
SEC16 homolog B, endoplasmic reticulum export factor
chr25_+_35058088 0.37 ENSDART00000156838
zgc:112234
chr12_-_42368296 0.37 ENSDART00000171075
zgc:111868
chr9_-_23891102 0.36 ENSDART00000186799
ankyrin repeat and SOCS box containing 18
chr18_+_40462445 0.36 ENSDART00000087645
UDP glucuronosyltransferase 5 family, polypeptide C2
chr16_+_19637384 0.36 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
metastasis associated in colon cancer 1
chr4_+_65607540 0.36 ENSDART00000192218
si:dkey-205i10.2
chr4_-_11403811 0.36 ENSDART00000067272
ENSDART00000140018
Pim proto-oncogene, serine/threonine kinase, related 173
chr25_+_20089986 0.36 ENSDART00000143441
ENSDART00000184073
troponin I4b, tandem duplicate 2
chr5_-_37116265 0.36 ENSDART00000057613
interleukin 13 receptor, alpha 2
chr17_+_45305645 0.35 ENSDART00000172488
calpain 3a, (p94)
chr15_-_42206890 0.35 ENSDART00000015843
paired box 3b
chr3_+_14558188 0.35 ENSDART00000143904
erythropoietin receptor
chr1_+_12178215 0.35 ENSDART00000090380
STRA6-like
chr25_+_35132090 0.35 ENSDART00000154377
si:dkey-261m9.6
chr2_+_7851493 0.35 ENSDART00000176910
si:ch211-38m6.6
chr5_-_3960161 0.34 ENSDART00000111453
myosin XIX
chr9_+_15893093 0.34 ENSDART00000099483
ENSDART00000134657
si:dkey-14o1.20
chr3_-_8130491 0.34 ENSDART00000162309
si:ch211-51i16.1
chr12_+_19030391 0.34 ENSDART00000153927
si:ch73-139e5.2
chr12_-_30540699 0.34 ENSDART00000167712
ENSDART00000102464
zgc:153920
chr20_-_21672970 0.34 ENSDART00000133286
si:ch211-207i1.2
chr19_-_9786914 0.34 ENSDART00000181669
si:dkey-14o18.2
chr24_-_2843107 0.34 ENSDART00000165290
cytochrome b5 type A (microsomal)
chr2_-_17115256 0.34 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr16_-_25607266 0.33 ENSDART00000192602
zgc:110410
chr25_-_17239008 0.33 ENSDART00000151965
ENSDART00000152106
ENSDART00000152107
cyclin D2, a
chr23_-_3758637 0.33 ENSDART00000131536
ENSDART00000139408
ENSDART00000137826
high mobility group AT-hook 1a
chr17_-_122680 0.33 ENSDART00000066430
actin, alpha, cardiac muscle 1b
chr16_-_31622777 0.33 ENSDART00000137311
ENSDART00000002930
PHD finger protein 20 like 1
chr25_-_27842654 0.33 ENSDART00000154852
ENSDART00000156906
ankyrin repeat and SOCS box containing 15a
chr9_-_29497916 0.33 ENSDART00000060246
DnaJ (Hsp40) homolog, subfamily C, member 3a
chr7_+_49664174 0.33 ENSDART00000137059
ENSDART00000131210
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr21_-_25741411 0.33 ENSDART00000101211
claudin h
chr12_-_3237561 0.33 ENSDART00000164665
si:ch1073-13h15.3
chr15_-_36365840 0.33 ENSDART00000192926
si:dkey-23k10.3
chr24_-_26369185 0.32 ENSDART00000080039
leucine rich repeat containing 31
chr8_+_28467893 0.32 ENSDART00000189724
solute carrier family 52 (riboflavin transporter), member 3
chr16_+_42465518 0.32 ENSDART00000058699
si:ch211-215k15.4
chr3_-_26204867 0.32 ENSDART00000103748
glycerophosphodiester phosphodiesterase domain containing 3a
chr23_+_10352921 0.31 ENSDART00000081193
si:ch211-133j6.3
chr15_-_35410860 0.31 ENSDART00000191267
MDS1 and EVI1 complex locus
chr2_-_32768951 0.31 ENSDART00000004712
beaded filament structural protein 2, phakinin
chr12_-_5418340 0.31 ENSDART00000028043
NOC3-like DNA replication regulator
chr14_+_18782610 0.31 ENSDART00000164468
si:ch211-111e20.1
chr20_-_29498178 0.31 ENSDART00000152986
ENSDART00000027851
ENSDART00000152954
ribonucleotide reductase M2 polypeptide
chr19_-_19721556 0.31 ENSDART00000165196
even-skipped homeobox 1
chr15_+_31466978 0.31 ENSDART00000017810
odorant receptor, family C, subfamily 102, member 2
chr21_-_18972206 0.31 ENSDART00000146743
Pim proto-oncogene, serine/threonine kinase, related 72
chr19_+_7636941 0.31 ENSDART00000081611
ENSDART00000163805
ENSDART00000112404
cingulin b
chr15_-_37767901 0.31 ENSDART00000154763
si:dkey-42l23.4
chr3_-_9488350 0.31 ENSDART00000186707

chr16_+_29586468 0.30 ENSDART00000148926
MCL1, BCL2 family apoptosis regulator b
chr12_+_16440708 0.30 ENSDART00000113810
ankyrin repeat domain 1b (cardiac muscle)
chr5_+_56026031 0.30 ENSDART00000050970
frizzled class receptor 9a
chr20_+_25586099 0.30 ENSDART00000063122
ENSDART00000134047
cytochrome P450, family 2, subfamily P, polypeptide 10
chr7_+_22982201 0.30 ENSDART00000134116
cyclin B3
chr16_+_35401543 0.30 ENSDART00000171608
RAB42, member RAS oncogene family
chr5_+_57658898 0.30 ENSDART00000074268
ENSDART00000124568
zgc:153929
chr5_-_61652254 0.30 ENSDART00000097364
draculin
chr4_-_43731342 0.30 ENSDART00000146627
si:ch211-226o13.3
chr5_-_64883082 0.29 ENSDART00000064983
ENSDART00000139066
keratin, type 1, gene c5
chr1_+_9966384 0.29 ENSDART00000132607
si:dkeyp-75b4.8
chr7_+_61184104 0.29 ENSDART00000110671
zgc:194930
chr3_+_3099492 0.29 ENSDART00000154156
si:dkey-30g5.1
chr2_-_28420415 0.29 ENSDART00000183857

chr4_+_26357221 0.29 ENSDART00000187684
ENSDART00000101545
ENSDART00000148296
ENSDART00000171433
troponin I, skeletal, slow d
chr17_-_8862424 0.28 ENSDART00000064633
NK-lysin tandem duplicate 4
chr19_+_31044487 0.28 ENSDART00000143494
ankyrin repeat and MYND domain containing 2b
chr12_-_30777540 0.28 ENSDART00000126466
ectonucleoside triphosphate diphosphohydrolase 1
chr4_+_49266048 0.28 ENSDART00000127767
ENSDART00000186362
si:ch211-42i6.2
chr7_-_35126374 0.28 ENSDART00000141211
hydroxysteroid (11-beta) dehydrogenase 2
chr2_-_36604589 0.28 ENSDART00000167352
T-cell receptor alpha/delta variable 41.0
chr5_-_54197084 0.28 ENSDART00000163640
G protein-coupled receptor kinase 1 b
chr12_-_13155653 0.28 ENSDART00000152467
CX chemokine ligand 34c
chr6_-_9922266 0.28 ENSDART00000151549
Pim proto-oncogene, serine/threonine kinase, related 73
chr17_-_6765877 0.28 ENSDART00000193102

chr1_-_9227804 0.28 ENSDART00000190360
guanine nucleotide binding protein (G protein), gamma 13a
chr19_-_4785734 0.27 ENSDART00000113088
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr8_-_36327328 0.27 ENSDART00000183333
zgc:103700
chr18_-_22713621 0.27 ENSDART00000079013
si:ch73-113g13.2
chr5_-_30984010 0.27 ENSDART00000182367
spinster homolog 3 (Drosophila)
chr17_+_24064014 0.27 ENSDART00000182782
ENSDART00000139063
ENSDART00000132755
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr7_-_22981796 0.27 ENSDART00000167565
si:dkey-171c9.3
chr14_-_9713549 0.27 ENSDART00000193356
ENSDART00000166739
si:zfos-2326c3.2
chr1_+_52735484 0.27 ENSDART00000182076

chr19_+_4051695 0.26 ENSDART00000166368
bloodthirsty-related gene family, member 24
chr5_-_30382925 0.26 ENSDART00000125381
grass carp reovirus (GCRV)-induced gene 2o
chr17_-_23609210 0.26 ENSDART00000064003
interferon-induced protein with tetratricopeptide repeats 15
chr9_+_22359919 0.26 ENSDART00000009591
crystallin, gamma S4
chr19_-_17208728 0.26 ENSDART00000151228
stathmin 1a
chr17_-_25737452 0.25 ENSDART00000152021
si:ch211-214p16.3
chr24_-_21913426 0.25 ENSDART00000081178
C1q and TNF related 9
chr7_+_22585447 0.25 ENSDART00000149144
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr7_+_22981909 0.25 ENSDART00000122449
cyclin B3
chr21_-_20342096 0.25 ENSDART00000065659
retinol binding protein 4, like
chr3_-_53114299 0.25 ENSDART00000109390

chr5_-_41645058 0.25 ENSDART00000051092
RIO kinase 2 (yeast)
chr12_-_30777743 0.25 ENSDART00000148888
ectonucleoside triphosphate diphosphohydrolase 1
chr15_-_34930727 0.25 ENSDART00000179723
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr13_+_22675802 0.25 ENSDART00000145538
ENSDART00000143312
zgc:193505
chr3_-_34092914 0.25 ENSDART00000151077
immunoglobulin heavy variable 4-6
chr3_-_50443607 0.25 ENSDART00000074036
recoverin a
chr4_+_25607743 0.25 ENSDART00000028297
acyl-CoA thioesterase 14
chr11_+_3501669 0.25 ENSDART00000160808
pseudouridylate synthase-like 1
chr22_-_18546241 0.25 ENSDART00000105404
ENSDART00000105405
cold inducible RNA binding protein b
chr15_-_3736149 0.25 ENSDART00000182986
lysophosphatidic acid receptor 6a
chr1_-_11596829 0.25 ENSDART00000140725
si:dkey-26i13.7
chr20_+_25568694 0.25 ENSDART00000063107
ENSDART00000063128
cytochrome P450, family 2, subfamily P, polypeptide 7
chr2_+_19633493 0.24 ENSDART00000147989
Pim proto-oncogene, serine/threonine kinase, related 54
chr4_+_70414733 0.24 ENSDART00000162778
si:dkey-190j3.3

Network of associatons between targets according to the STRING database.

First level regulatory network of sox10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0046952 ketone body catabolic process(GO:0046952)
0.2 0.8 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.2 0.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 0.5 GO:0046125 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.5 GO:0051352 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 0.7 GO:0090133 adherens junction maintenance(GO:0034334) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 0.3 GO:0072196 proximal/distal pattern formation involved in nephron development(GO:0072047) proximal/distal pattern formation involved in pronephric nephron development(GO:0072196)
0.1 0.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 0.4 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.5 GO:0071405 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.1 0.8 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 0.6 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.4 GO:0070973 positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.6 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.3 GO:0071939 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.1 0.7 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.2 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 0.7 GO:0006032 chitin catabolic process(GO:0006032)
0.1 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.5 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.1 0.5 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.2 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.3 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 0.5 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.3 GO:0034650 cortisol metabolic process(GO:0034650)
0.0 0.2 GO:1901827 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.0 0.1 GO:1902176 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.0 0.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.4 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:1902042 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.3 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.1 GO:0008344 adult locomotory behavior(GO:0008344)
0.0 0.2 GO:0035678 neuromast hair cell morphogenesis(GO:0035678)
0.0 0.2 GO:0070285 pigment cell development(GO:0070285)
0.0 0.4 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.3 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.2 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.2 GO:0006833 water transport(GO:0006833)
0.0 0.8 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.3 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 2.4 GO:0006941 striated muscle contraction(GO:0006941)
0.0 0.3 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.1 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 0.3 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.0 0.4 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.9 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 1.3 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.2 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.2 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.5 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0045823 positive regulation of heart contraction(GO:0045823)
0.0 0.1 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0042664 negative regulation of endodermal cell fate specification(GO:0042664)
0.0 0.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 2.0 GO:0006956 complement activation(GO:0006956)
0.0 0.6 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.2 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.6 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.3 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.1 GO:0035093 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.0 0.9 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.6 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.3 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.4 GO:0071222 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.2 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.3 GO:0014812 muscle cell migration(GO:0014812)
0.0 1.2 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0055016 hypochord development(GO:0055016)
0.0 0.3 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.5 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0045095 keratin filament(GO:0045095)
0.1 0.5 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.8 GO:0042627 chylomicron(GO:0042627)
0.1 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0097268 cytoophidium(GO:0097268)
0.0 0.4 GO:0031526 brush border membrane(GO:0031526)
0.0 2.0 GO:0005861 troponin complex(GO:0005861)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0044545 NSL complex(GO:0044545)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)
0.0 0.5 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 0.8 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.2 0.6 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.2 0.8 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.2 0.8 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 0.9 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.6 GO:0098634 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.7 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.5 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 0.5 GO:0017113 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.1 0.5 GO:0048156 tau protein binding(GO:0048156)
0.1 0.3 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.2 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 0.5 GO:0034632 retinol transporter activity(GO:0034632)
0.1 0.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 0.4 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.6 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.7 GO:0004568 chitinase activity(GO:0004568)
0.1 0.4 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.6 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.4 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.1 0.3 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.1 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.7 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.4 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 1.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.0 1.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 1.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.5 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.3 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.2 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0043394 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.1 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID EPO PATHWAY EPO signaling pathway
0.0 0.7 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules