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PRJNA207719: Tissue specific transcriptome profiling

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Results for smad3a+smad3b

Z-value: 1.90

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Transcription factors associated with smad3a+smad3b

Gene Symbol Gene ID Gene Info
ENSDARG00000010207 SMAD family member 3b
ENSDARG00000036096 SMAD family member 3a
ENSDARG00000117146 SMAD family member 3a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
smad3adr11_v1_chr7_-_34149263_34149263-0.828.6e-02Click!
smad3bdr11_v1_chr18_+_19772874_19772874-0.573.2e-01Click!

Activity profile of smad3a+smad3b motif

Sorted Z-values of smad3a+smad3b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_59073203 2.32 ENSDART00000149937
ENSDART00000162201
si:zfos-2330d3.3
zgc:173915
chr22_+_661711 1.80 ENSDART00000113795
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr22_+_661505 1.75 ENSDART00000149460
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr5_+_22459087 1.58 ENSDART00000134781

chr19_-_5332784 1.55 ENSDART00000010373
keratin, type 1, gene 19d
chr1_-_59104145 1.48 ENSDART00000132495
ENSDART00000152457
si:zfos-2330d3.1
si:zfos-2330d3.7
chr23_+_44614056 1.47 ENSDART00000188379
enolase 3, (beta, muscle)
chr14_+_38786298 1.39 ENSDART00000164440
si:ch211-195b11.3
chr18_+_13164325 1.34 ENSDART00000189057
tyrosine aminotransferase
chr1_+_59073436 1.34 ENSDART00000161642
si:zfos-2330d3.3
chr2_+_32796873 1.32 ENSDART00000077511
chemokine (C-C motif) receptor 9a
chr4_-_11577253 1.32 ENSDART00000144452
neuroepithelial cell transforming 1
chr10_+_17088261 1.29 ENSDART00000132103
si:dkey-106l3.7
chr19_+_4068134 1.18 ENSDART00000158285
bloodthirsty-related gene family, member 26
chr13_+_2830574 1.16 ENSDART00000138143
si:ch211-233m11.1
chr6_+_49926115 1.15 ENSDART00000018523
adenosylhomocysteinase
chr2_-_7666021 1.14 ENSDART00000180007

chr3_-_48980319 1.10 ENSDART00000165319
finTRIM family, member 42
chr7_+_21180747 1.08 ENSDART00000185543
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr12_+_46386983 1.05 ENSDART00000183982
Danio rerio legumain (LOC100005356), mRNA.
chr16_-_17699111 1.02 ENSDART00000108581
si:dkey-17m8.1
chr19_+_4062101 1.00 ENSDART00000166773
bloodthirsty-related gene family, member 25
chr25_+_35065802 0.97 ENSDART00000182372
zgc:165555
chr1_-_43920371 0.95 ENSDART00000109283
secretory calcium-binding phosphoprotein 7
chr3_-_4591643 0.94 ENSDART00000138144
finTRIM family, member 50
chr1_-_43920576 0.90 ENSDART00000191914
secretory calcium-binding phosphoprotein 7
chr18_+_20560442 0.89 ENSDART00000151990
WEE1 homolog 2 (S. pombe)
chr5_-_24124118 0.89 ENSDART00000051550
capping protein (actin filament), gelsolin-like a
chr13_+_17694845 0.87 ENSDART00000079778
interferon-induced protein with tetratricopeptide repeats 8
chr15_+_46344655 0.86 ENSDART00000155893
si:ch1073-340i21.2
chr21_+_26071874 0.85 ENSDART00000003001
ENSDART00000146573
ribosomal protein L23a
chr4_-_18954001 0.84 ENSDART00000144814
si:dkey-31f5.8
chr19_+_627899 0.81 ENSDART00000148508
telomerase reverse transcriptase
chr4_+_28997595 0.81 ENSDART00000133357
si:dkey-13e3.1
chr1_-_52494122 0.80 ENSDART00000131407
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr18_-_26715655 0.78 ENSDART00000181497
MALT paracaspase 3
chr8_-_38201415 0.78 ENSDART00000155189
PDZ and LIM domain 2 (mystique)
chr7_+_2228276 0.77 ENSDART00000064294
si:dkey-187j14.4
chr22_-_10591876 0.76 ENSDART00000105846
si:dkey-42i9.8
chr19_+_4061699 0.74 ENSDART00000158309
ENSDART00000166512
bloodthirsty-related gene family, member 25
bloodthirsty-related gene family, member 26
chr21_-_32036597 0.74 ENSDART00000114964
zgc:165573
chr22_+_14836291 0.74 ENSDART00000122740
GTP binding protein 1, like
chr15_-_25556074 0.72 ENSDART00000124677
matrix metallopeptidase 20a (enamelysin)
chr15_+_38007237 0.71 ENSDART00000182271

chr15_+_47525073 0.70 ENSDART00000067583
SID1 transmembrane family, member 2
chr10_-_36214582 0.70 ENSDART00000166471
odorant receptor, family D, subfamily 109, member 11
chr3_-_27784457 0.68 ENSDART00000019098
deoxyribonuclease I
chr6_-_8498908 0.68 ENSDART00000149222
peptidoglycan recognition protein 2
chr2_-_20599315 0.68 ENSDART00000114199
si:ch211-267e7.3
chr7_+_5959203 0.68 ENSDART00000110813
zgc:165555
chr4_+_15944245 0.67 ENSDART00000134594
si:dkey-117n7.3
chr7_+_4911404 0.67 ENSDART00000137385
si:dkey-28d5.11
chr3_+_52753416 0.66 ENSDART00000171185
GEM interacting protein
chr24_-_6038025 0.66 ENSDART00000077819
ENSDART00000139216
finTRIM family, member 61
chr19_-_3754327 0.65 ENSDART00000168463
bloodthirsty-related gene family, member 21
chr1_-_59130383 0.64 ENSDART00000171552

chr19_+_4054036 0.64 ENSDART00000171802
bloodthirsty-related gene family, member 24
chr25_-_29415369 0.64 ENSDART00000110774
ENSDART00000019183
UDP glucuronosyltransferase 5 family, polypeptide A2
UDP glucuronosyltransferase 5 family, polypeptide A1
chr19_+_7043634 0.63 ENSDART00000133954
major histocompatibility complex class I UKA
chr24_+_39990695 0.63 ENSDART00000040281

chr6_-_8498676 0.63 ENSDART00000148627
peptidoglycan recognition protein 2
chr25_-_35126024 0.62 ENSDART00000185109
zgc:165555
chr4_+_50401133 0.62 ENSDART00000150644
si:dkey-156k2.7
chr12_-_21681509 0.61 ENSDART00000112726
essential meiotic structure-specific endonuclease 1
chr13_-_10945288 0.61 ENSDART00000114315
ENSDART00000164667
ENSDART00000159482
ATP-binding cassette, sub-family G (WHITE), member 8
chr7_+_66822229 0.61 ENSDART00000112109
lymphatic vessel endothelial hyaluronic receptor 1a
chr3_-_4501026 0.61 ENSDART00000163052
zgc:162198
chr15_-_25556227 0.60 ENSDART00000156445
matrix metallopeptidase 20a (enamelysin)
chr25_+_16194979 0.60 ENSDART00000185592
ENSDART00000158582
ENSDART00000161109
ENSDART00000139013
microtubule associated monooxygenase, calponin and LIM domain containing 2b
chr5_+_38685089 0.60 ENSDART00000139743
si:dkey-58f10.10
chr3_+_13603272 0.59 ENSDART00000185084
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr12_-_44016898 0.59 ENSDART00000175304
si:dkey-201i2.4
chr22_+_19478140 0.58 ENSDART00000135291
ENSDART00000136576
si:dkey-78l4.8
chr16_-_53259409 0.58 ENSDART00000157080
si:ch211-269k10.4
chr7_-_69121896 0.57 ENSDART00000130227
cysteine-rich secretory protein LCCL domain containing 2
chr14_-_32876280 0.57 ENSDART00000173168
si:rp71-46j2.7
chr25_-_16552135 0.57 ENSDART00000125836
si:ch211-266k8.4
chr2_+_42236118 0.56 ENSDART00000114162
ENSDART00000141199
finTRIM family, member 2
chr15_-_41486793 0.56 ENSDART00000138525
si:ch211-187g4.1
chr13_+_10945337 0.56 ENSDART00000091845
ATP-binding cassette, sub-family G (WHITE), member 5
chr1_-_59139599 0.55 ENSDART00000152233
si:ch1073-110a20.3
chr10_-_24689725 0.55 ENSDART00000079566
si:ch211-287a12.9
chr25_+_36315127 0.55 ENSDART00000191984
zgc:165555
chr7_+_24523017 0.55 ENSDART00000077047
bloodthirsty-related gene family, member 9
chr9_+_29616854 0.55 ENSDART00000033902
ENSDART00000143493
PHD finger protein 11
chr5_+_62723233 0.55 ENSDART00000183718
nanos homolog 2
chr24_-_33291784 0.54 ENSDART00000124938
si:ch1073-406l10.2
chr2_-_59265521 0.54 ENSDART00000146341
ENSDART00000097799
finTRIM family, member 33
chr6_-_43283122 0.53 ENSDART00000186022
FERM domain containing 4Ba
chr22_-_17499513 0.52 ENSDART00000105460
si:ch211-197g15.6
chr3_-_2091029 0.52 ENSDART00000141464
si:dkey-88j15.4
chr14_-_7128980 0.51 ENSDART00000171311
si:ch73-43g23.1
chr5_+_38752287 0.51 ENSDART00000133571
chemokine (C-X-C motif) ligand 11, duplicate 8
chr15_-_37834433 0.50 ENSDART00000189748
si:dkey-238d18.3
chr3_+_34120191 0.50 ENSDART00000020017
ENSDART00000151700
aldehyde dehydrogenase 3 family, member B1
chr23_+_10352921 0.50 ENSDART00000081193
si:ch211-133j6.3
chr10_-_24416471 0.50 ENSDART00000135985
hephaestin-like 1b
chr5_+_38673168 0.49 ENSDART00000135267
si:dkey-58f10.12
chr20_-_52199296 0.48 ENSDART00000131806
ENSDART00000143668
H2.0-like homeo box 1 (Drosophila)
chr4_+_35576329 0.48 ENSDART00000171191
ENSDART00000161611
si:dkeyp-4c4.2
chr16_-_32204470 0.48 ENSDART00000143928
RWD domain containing 1
chr20_-_2619316 0.47 ENSDART00000185777
BUB1 mitotic checkpoint serine/threonine kinase
chr17_-_27273296 0.46 ENSDART00000077087
inhibitor of DNA binding 3
chr17_+_14886828 0.45 ENSDART00000010507
ENSDART00000131052
prostaglandin E receptor 2a (subtype EP2)
chr23_-_19230627 0.45 ENSDART00000007122
guanylate cyclase activator 1B
chr25_+_36345867 0.44 ENSDART00000186527
zgc:165555
chr16_+_15114645 0.44 ENSDART00000158483
MDM2 binding protein
chr14_-_40797117 0.44 ENSDART00000122369
E74-like ETS transcription factor 1
chr18_-_8885792 0.43 ENSDART00000143619
si:dkey-95h12.1
chr7_-_24181159 0.43 ENSDART00000181206
zgc:153151
chr25_+_35056619 0.42 ENSDART00000154389
histone cluster 1 H4 family member j
chr6_+_28051978 0.41 ENSDART00000143218
si:ch73-194h10.2
chr2_+_25560556 0.41 ENSDART00000133623
phospholipase D1a
chr7_-_51528661 0.40 ENSDART00000174263
NHS-like 2
chr21_-_40173821 0.40 ENSDART00000180667
solute carrier organic anion transporter family, member 2B1
chr8_-_18203274 0.40 ENSDART00000134078
ENSDART00000180235
ENSDART00000080006
ENSDART00000125418
ENSDART00000142114
ELOVL fatty acid elongase 8b
chr21_+_2203316 0.40 ENSDART00000185659

chr16_+_19013257 0.40 ENSDART00000144102
si:ch211-254p10.2
chr20_+_46213553 0.39 ENSDART00000100532
syntaxin 7-like
chr7_-_3721671 0.38 ENSDART00000062732
si:ch211-282j17.8
chr22_-_35385810 0.38 ENSDART00000111824
5-hydroxytryptamine receptor 3C
chr1_-_57129179 0.37 ENSDART00000157226
ENSDART00000152469
si:ch73-94k4.2
chr14_-_28052474 0.37 ENSDART00000172948
ENSDART00000135337
si:ch211-220e11.3
zgc:64189
chr22_+_36914636 0.37 ENSDART00000150948
Pim proto-oncogene, serine/threonine kinase, related 205
chr12_+_16949391 0.37 ENSDART00000152635
zgc:174153
chr4_-_77636185 0.36 ENSDART00000152915
ENSDART00000131964
si:dkey-61p9.9
chr12_-_44122412 0.35 ENSDART00000169094
si:ch73-329n5.3
chr17_-_45386546 0.35 ENSDART00000182647
transmembrane protein 206
chr12_-_44010532 0.35 ENSDART00000183875
si:ch211-182p11.1
chr6_-_39649504 0.35 ENSDART00000179960
ENSDART00000190951
La ribonucleoprotein domain family, member 4Ab
chr18_-_22696170 0.34 ENSDART00000147183
si:dkey-11d18.4
chr4_+_47736069 0.33 ENSDART00000193329
si:ch211-196f19.1
chr6_-_39158953 0.33 ENSDART00000050682
signal transducer and activator of transcription 2
chr2_-_59376399 0.33 ENSDART00000137134
finTRIM family, member 38
chr3_+_52275691 0.33 ENSDART00000190109

chr22_+_1526040 0.33 ENSDART00000164089
ENSDART00000159126
si:ch211-255f4.6
chr12_+_4573696 0.32 ENSDART00000152534
si:dkey-94f20.4
chr4_-_71267461 0.32 ENSDART00000161219
ENSDART00000151838
si:dkeyp-51g9.4
chr12_-_44151296 0.32 ENSDART00000168734
si:ch73-329n5.3
chr8_-_3346692 0.31 ENSDART00000057874
zgc:103510
chr10_+_23441488 0.31 ENSDART00000100783
si:ch73-122g19.1
chr11_+_30310170 0.31 ENSDART00000127797
UDP glucuronosyltransferase 1 family, polypeptide B3
chr3_-_62417677 0.31 ENSDART00000101888
somatostatin receptor 2b
chr20_-_54377933 0.30 ENSDART00000182664
ectonucleoside triphosphate diphosphohydrolase 5b
chr7_+_29890292 0.30 ENSDART00000170403
ENSDART00000168600
talin 2a
chr18_-_22696357 0.29 ENSDART00000100955
si:dkey-11d18.4
chr1_+_47178529 0.29 ENSDART00000158432
ENSDART00000074450
ENSDART00000137448
MORC family CW-type zinc finger 3b
chr5_+_17780475 0.29 ENSDART00000110783
ENSDART00000115227
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr4_-_73227710 0.29 ENSDART00000193165

chr22_-_6801876 0.29 ENSDART00000135726
si:ch1073-188e1.1
chr3_-_33029426 0.29 ENSDART00000181287

chr19_-_24218942 0.29 ENSDART00000189198

chr16_+_25259313 0.28 ENSDART00000058938
F-box protein 32
chr12_-_17479078 0.28 ENSDART00000079115
3'-phosphoadenosine 5'-phosphosulfate synthase 2b
chr8_-_13541514 0.28 ENSDART00000063834
zgc:86586
chr8_-_3336273 0.27 ENSDART00000081160
zgc:173737
chr4_-_25812329 0.27 ENSDART00000146658
transmembrane and coiled-coil domain family 3
chr18_-_31227615 0.26 ENSDART00000003210
melanocortin 1 receptor
chr17_-_51679784 0.26 ENSDART00000103374
ATPase H+ transporting V1 subunit C2
chr2_-_55337585 0.26 ENSDART00000177924
tropomyosin 4b
chr10_+_36345176 0.25 ENSDART00000099397
odorant receptor, family C, subfamily 105, member 1
chr6_-_39051319 0.25 ENSDART00000155093
tensin 2b
chr17_-_50355512 0.25 ENSDART00000041685
otoferlin b
chr5_+_7564644 0.25 ENSDART00000192173

chr16_-_22729119 0.25 ENSDART00000132944
toll-like receptor 19
chr4_-_62503772 0.25 ENSDART00000108891
si:dkey-165b20.1
chr8_+_23194212 0.24 ENSDART00000028946
ENSDART00000186842
ENSDART00000137815
ENSDART00000136914
ENSDART00000144855
ENSDART00000182689
tumor protein D52-like 2a
chr22_+_8489400 0.24 ENSDART00000129119

chr18_+_17611627 0.24 ENSDART00000046891
cholesteryl ester transfer protein, plasma
chr16_+_30961822 0.24 ENSDART00000059187
glutathione S-transferase kappa 2
chr7_-_6100716 0.24 ENSDART00000173003
si:cabz01036006.1
chr2_-_47904043 0.23 ENSDART00000185328
ENSDART00000126740
finTRIM family, member 22
chr11_-_27874116 0.23 ENSDART00000180579
eukaryotic translation initiation factor 4 gamma, 3a
chr24_+_29912509 0.23 ENSDART00000168422
ferric-chelate reductase 1b
chr4_-_49580812 0.23 ENSDART00000180306
si:dkey-159n16.2
chr17_-_23609210 0.22 ENSDART00000064003
interferon-induced protein with tetratricopeptide repeats 15
chr2_+_11670270 0.22 ENSDART00000100524
finTRIM family, member 1
chr2_+_42318012 0.22 ENSDART00000138137
finTRIM family, member 8
chr20_+_46897504 0.22 ENSDART00000158124
si:ch73-21k16.1
chr2_-_58902477 0.22 ENSDART00000061638
ENSDART00000172822
MAU2 sister chromatid cohesion factor
chr4_+_16787488 0.22 ENSDART00000143006
golgi transport 1Ba
chr2_+_47927026 0.21 ENSDART00000143023
finTRIM family, member 25
chr4_-_64141714 0.21 ENSDART00000128628

chr11_+_12175162 0.21 ENSDART00000125446
si:ch211-156l18.7
chr17_+_12265095 0.21 ENSDART00000153812
Pim proto-oncogene, serine/threonine kinase, related 168
chr5_+_4806851 0.20 ENSDART00000067599
angiopoietin-like 2a
chr11_+_30306606 0.20 ENSDART00000128276
ENSDART00000190222
UDP glucuronosyltransferase 1 family, polypeptide B4
chr23_+_44633858 0.20 ENSDART00000180728
si:ch73-265d7.2
chr19_+_11256617 0.20 ENSDART00000159577
si:ch73-171o20.1
chr4_-_76488581 0.20 ENSDART00000174291
finTRIM family, member 51
chr18_-_25402715 0.19 ENSDART00000179852
gonadotropin releasing hormone receptor 4
chr5_+_24305877 0.19 ENSDART00000144226
cathepsin L, like
chr12_-_20795867 0.18 ENSDART00000152835
ENSDART00000153424
NME/NM23 nucleoside diphosphate kinase 2a
chr7_-_16214889 0.18 ENSDART00000076318
ENSDART00000173946
bloodthirsty-related gene family, member 6
chr2_-_59285407 0.18 ENSDART00000181616
finTRIM family, member 34
chr17_-_45386823 0.18 ENSDART00000156002
transmembrane protein 206
chr23_+_36052944 0.18 ENSDART00000103149
homeobox C13a
chr21_+_25533908 0.18 ENSDART00000185225
NLR family, CARD domain containing 3-like 1
chr2_+_19578446 0.17 ENSDART00000164758
Pim proto-oncogene, serine/threonine kinase, related 50
chr20_+_25711718 0.17 ENSDART00000033436
centrosomal protein 135

Network of associatons between targets according to the STRING database.

First level regulatory network of smad3a+smad3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0098581 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.3 0.9 GO:0060631 regulation of meiosis I(GO:0060631)
0.3 4.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 0.8 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.2 1.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 1.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 1.5 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 0.7 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 1.3 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 0.6 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.3 GO:0050428 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.4 GO:0034695 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.1 0.2 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.1 1.3 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.1 0.2 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.1 0.5 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.4 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.1 0.6 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 1.0 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.4 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 1.3 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.2 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.5 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.0 0.3 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.3 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.9 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 2.6 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0060337 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.4 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.4 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 0.6 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 2.5 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.3 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:0007414 axonal defasciculation(GO:0007414)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.5 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 1.1 GO:0051607 defense response to virus(GO:0051607)
0.0 4.2 GO:0006954 inflammatory response(GO:0006954)
0.0 0.3 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.1 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.5 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.1 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.2 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.2 1.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.6 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 2.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.5 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 1.8 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.5 GO:0005844 polysome(GO:0005844)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.4 1.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 0.8 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.2 1.0 GO:0008432 JUN kinase binding(GO:0008432)
0.2 1.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.6 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.1 0.3 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.3 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.8 GO:0004046 aminoacylase activity(GO:0004046)
0.1 4.3 GO:0003823 antigen binding(GO:0003823)
0.1 0.7 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.4 GO:0004630 phospholipase D activity(GO:0004630)
0.1 0.4 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048) cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.4 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.2 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 1.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.7 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.8 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 1.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 1.3 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.6 GO:0042923 neuropeptide binding(GO:0042923)
0.0 2.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.9 GO:0019843 rRNA binding(GO:0019843)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 2.2 GO:0046982 protein heterodimerization activity(GO:0046982)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 1.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.8 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport