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PRJNA207719: Tissue specific transcriptome profiling

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Results for runx1

Z-value: 2.66

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Transcription factors associated with runx1

Gene Symbol Gene ID Gene Info
ENSDARG00000087646 RUNX family transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
runx1dr11_v1_chr1_-_1402303_1402303-0.711.8e-01Click!

Activity profile of runx1 motif

Sorted Z-values of runx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_5543677 2.70 ENSDART00000146161
ENSDART00000136189
nicotinamide nucleotide transhydrogenase 2
chr17_-_2039511 2.30 ENSDART00000160223
serine peptidase inhibitor, Kunitz type 1 a
chr8_-_21372446 2.28 ENSDART00000061481
ENSDART00000079293
elastase 2 like
chr8_+_21353878 2.01 ENSDART00000056420
aminolevulinate, delta-, synthase 2
chr7_-_7810348 1.94 ENSDART00000171984
chemokine (C-X-C motif) ligand 19
chr4_-_77557279 1.92 ENSDART00000180113

chr7_+_31879986 1.87 ENSDART00000138491
myosin binding protein C, cardiac
chr24_-_9989634 1.86 ENSDART00000115275
zgc:152652
chr20_-_14054083 1.70 ENSDART00000009549
Rh associated glycoprotein
chr22_+_34616151 1.47 ENSDART00000155399
ENSDART00000104705
si:ch1073-214b20.2
chr4_+_77973876 1.43 ENSDART00000057423
telomeric repeat binding factor a
chr4_-_68563862 1.43 ENSDART00000182970

chr14_+_38786298 1.42 ENSDART00000164440
si:ch211-195b11.3
chr7_+_31879649 1.40 ENSDART00000099789
myosin binding protein C, cardiac
chr9_+_23770666 1.38 ENSDART00000182493
si:ch211-219a4.3
chr7_+_39706004 1.37 ENSDART00000161856
chemokine (C-C motif) ligand 36, duplicate 1
chr4_+_5537101 1.36 ENSDART00000008692
si:dkey-14d8.7
chr10_-_15128771 1.27 ENSDART00000101261
secreted phosphoprotein 1
chr3_-_16784280 1.23 ENSDART00000137108
ENSDART00000137276
si:dkey-30j10.5
chr8_+_47099033 1.14 ENSDART00000142979
Rho guanine nucleotide exchange factor (GEF) 16
chr6_-_43449013 1.12 ENSDART00000122423
2-epi-5-epi-valiolone synthase
chr9_+_30464641 1.12 ENSDART00000128357
gap junction protein, alpha 5a
chr19_-_7144548 1.10 ENSDART00000147177
ENSDART00000134850
proteasome subunit beta 8A
proteasome subunit beta 13a
chr2_+_36898982 1.07 ENSDART00000084859
RAB GTPase activating protein 1-like 2
chr12_+_34273240 1.06 ENSDART00000037904
suppressor of cytokine signaling 3b
chr22_+_21324398 1.05 ENSDART00000168509
SHC (Src homology 2 domain containing) transforming protein 2
chr22_+_19486711 1.05 ENSDART00000144389
ENSDART00000139256
ENSDART00000160855
si:dkey-78l4.10
chr19_+_4068134 1.04 ENSDART00000158285
bloodthirsty-related gene family, member 26
chr17_-_8899323 1.04 ENSDART00000081590
NK-lysin tandem duplicate 1
chr19_-_40191358 1.03 ENSDART00000183919
granulin 1
chr16_-_17300030 1.03 ENSDART00000149267
Kell blood group, metallo-endopeptidase
chr1_-_38195012 1.02 ENSDART00000020409
heart and neural crest derivatives expressed 2
chr5_+_57658898 1.02 ENSDART00000074268
ENSDART00000124568
zgc:153929
chr10_+_2742499 1.01 ENSDART00000122847
G protein-coupled receptor kinase 5
chr21_-_28439596 1.01 ENSDART00000089980
ENSDART00000132844
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_-_5372572 1.00 ENSDART00000151326
keratin 17
chr5_+_13373593 1.00 ENSDART00000051668
ENSDART00000183883
chemokine (C-C motif) ligand 19a, tandem duplicate 2
chr18_+_35742838 1.00 ENSDART00000088504
ENSDART00000140386
RAS guanyl releasing protein 4
chr22_-_5323482 0.99 ENSDART00000145785
sphingosine-1-phosphate receptor 4
chr3_-_34022076 0.99 ENSDART00000150907
ENSDART00000151092
immunoglobulin heavy variable 1-4
immunoglobulin heavy variable 1-4
chr1_+_55703120 0.98 ENSDART00000141089
adhesion G protein-coupled receptor E6
chr10_+_9550419 0.98 ENSDART00000064977
si:ch211-243g18.2
chr4_-_13502549 0.96 ENSDART00000140366
si:ch211-266a5.12
chr21_-_43616586 0.94 ENSDART00000036537
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 2
chr10_+_17088261 0.94 ENSDART00000132103
si:dkey-106l3.7
chr3_-_21382491 0.93 ENSDART00000016562
integrin, alpha 2b
chr14_+_22022441 0.92 ENSDART00000149121
cardiotrophin-like cytokine factor 1
chr23_-_36316352 0.92 ENSDART00000014840
nuclear factor, erythroid 2
chr17_+_5426087 0.92 ENSDART00000131430
ENSDART00000188636
runt-related transcription factor 2a
chr15_+_37412883 0.91 ENSDART00000156474
zinc finger and BTB domain containing 32
chr21_+_25198637 0.89 ENSDART00000164972
si:dkey-183i3.6
chr13_-_25305179 0.89 ENSDART00000110064
plasminogen activator, urokinase a
chr4_-_13518381 0.88 ENSDART00000067153
interferon, gamma 1-1
chr17_+_1627379 0.88 ENSDART00000184050

chr8_+_25359394 0.88 ENSDART00000111248
si:dkey-183p4.10
chr13_-_37122217 0.87 ENSDART00000133242
spectrin repeat containing, nuclear envelope 2b
chr8_-_49207319 0.86 ENSDART00000022870
family with sequence similarity 110, member A
chr21_+_11560153 0.86 ENSDART00000065842
CD8a molecule
chr16_-_22194400 0.86 ENSDART00000186042
interleukin 6 receptor
chr22_+_19494996 0.85 ENSDART00000140829
ENSDART00000135168
si:dkey-78l4.10
chr2_-_40199780 0.85 ENSDART00000113901
chemokine (C-C motif) ligand 34a, duplicate 4
chr1_+_54650048 0.84 ENSDART00000141207
si:ch211-202h22.7
chr25_-_13202208 0.84 ENSDART00000168155
si:ch211-194m7.4
chr3_+_14641962 0.84 ENSDART00000091070
zgc:158403
chr1_+_109798 0.83 ENSDART00000165402
zgc:163025
chr14_-_11430566 0.83 ENSDART00000137154
ENSDART00000091158
immunoresponsive gene 1, like
chr4_-_26108053 0.83 ENSDART00000066951
si:ch211-244b2.4
chr6_+_45932276 0.83 ENSDART00000103491
retinol binding protein 7b, cellular
chr1_-_12027 0.83 ENSDART00000164359
ribosomal protein L24
chr9_+_48108174 0.83 ENSDART00000077260
chemokine (C-X-C motif) receptor 2
chr24_-_25244637 0.82 ENSDART00000153798
HERV-H LTR-associating 2b, tandem duplicate 2
chr23_+_17417539 0.81 ENSDART00000182605

chr2_+_51028269 0.81 ENSDART00000161254
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr2_-_5475910 0.81 ENSDART00000100954
ENSDART00000172143
ENSDART00000132496
protein C (inactivator of coagulation factors Va and VIIIa), a
protein C (inactivator of coagulation factors Va and VIIIa), a
chr12_+_804314 0.81 ENSDART00000082169
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2b
chr8_+_25342896 0.80 ENSDART00000129032

chr6_-_13498745 0.80 ENSDART00000027684
ENSDART00000189438
myosin light chain kinase b
chr25_+_19680962 0.80 ENSDART00000167260
si:dkeyp-110c12.3
chr8_+_19356072 0.79 ENSDART00000063272
macrophage expressed 1, tandem duplicate 2
chr7_-_60831082 0.78 ENSDART00000073654
ENSDART00000136999
pyruvate carboxylase b
chr16_-_51254694 0.77 ENSDART00000148894
serpin peptidase inhibitor, clade B (ovalbumin), member 14
chr19_+_4062101 0.77 ENSDART00000166773
bloodthirsty-related gene family, member 25
chr3_-_7948799 0.77 ENSDART00000163714
tripartite motif containing 35-24
chr22_+_9772754 0.77 ENSDART00000130194

chr1_+_55140970 0.77 ENSDART00000039807
myoglobin
chr11_+_37216668 0.76 ENSDART00000173076
zgc:112265
chr3_+_22335030 0.76 ENSDART00000055676
zgc:103564
chr17_+_5976683 0.76 ENSDART00000110276
zgc:194275
chr16_-_17056630 0.76 ENSDART00000138715
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr20_+_1398564 0.75 ENSDART00000002242
liver-enriched gene 1, tandem duplicate 2
chr3_+_3598555 0.75 ENSDART00000191152

chr20_+_54034677 0.75 ENSDART00000173317
ENSDART00000173215
si:dkey-241l7.2
chr5_+_43783360 0.75 ENSDART00000019431
nitric oxide synthase 2a, inducible
chr7_+_24523017 0.75 ENSDART00000077047
bloodthirsty-related gene family, member 9
chr10_-_8053385 0.74 ENSDART00000142714
si:ch211-251f6.7
chr3_+_14558188 0.74 ENSDART00000143904
erythropoietin receptor
chr4_+_39766931 0.74 ENSDART00000138663
si:dkeyp-85d8.1
chr18_+_22109379 0.74 ENSDART00000147230
zgc:158868
chr6_-_15096556 0.73 ENSDART00000185327
four and a half LIM domains 2b
chr13_+_41819817 0.73 ENSDART00000185778

chr19_-_35428815 0.73 ENSDART00000169006
ENSDART00000003167
adenylate kinase 2
chr14_+_34501245 0.73 ENSDART00000131424
lymphocyte cytosolic protein 2b
chr16_-_31675669 0.72 ENSDART00000168848
ENSDART00000158331
complement component 1, r subcomponent
chr19_-_40192249 0.72 ENSDART00000051972
granulin 1
chr12_+_38940731 0.72 ENSDART00000193360
si:dkey-239b22.1
chr11_+_43431289 0.72 ENSDART00000192526
solute carrier family 29 (equilibrative nucleoside transporter), member 1b
chr2_+_32796873 0.72 ENSDART00000077511
chemokine (C-C motif) receptor 9a
chr14_-_22118055 0.71 ENSDART00000179892
si:dkey-6i22.5
chr3_+_30968176 0.71 ENSDART00000186266
perforin 1.9
chr22_-_31020690 0.71 ENSDART00000130604
ssu-2 homolog, tandem duplicate 4
chr22_+_9862243 0.71 ENSDART00000105942
si:dkey-253d23.3
chr1_-_7951002 0.71 ENSDART00000138187
si:dkey-79f11.8
chr7_+_41295974 0.70 ENSDART00000173568
ENSDART00000173544
si:dkey-86l18.10
chr16_-_31686602 0.70 ENSDART00000170357
complement component 1, s subcomponent
chr9_-_3496548 0.69 ENSDART00000102876
cytochrome b reductase 1
chr3_+_19621034 0.69 ENSDART00000025358
integrin beta 3a
chr1_-_43933271 0.69 ENSDART00000121605
secretory calcium-binding phosphoprotein 6
chr25_-_23526058 0.69 ENSDART00000191331
ENSDART00000062930
pleckstrin homology-like domain, family A, member 2
chr22_-_10470663 0.69 ENSDART00000143352
osteomodulin
chr1_-_53476758 0.69 ENSDART00000074221
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2a
chr4_+_76735113 0.68 ENSDART00000075602
membrane-spanning 4-domains, subfamily A, member 17A.6
chr10_+_16756546 0.68 ENSDART00000168624

chr8_+_37749263 0.68 ENSDART00000108556
ENSDART00000147942
nucleophosmin/nucleoplasmin, 2a
chr22_-_30770751 0.68 ENSDART00000172115

chr13_-_33170733 0.68 ENSDART00000057382
fibulin 5
chr14_-_46198373 0.68 ENSDART00000031640
ENSDART00000132966
zgc:113425
chr14_+_29941445 0.68 ENSDART00000181761
family with sequence similarity 149 member A
chr4_+_37952218 0.67 ENSDART00000186865
si:dkeyp-82b4.2
chr6_+_34868156 0.67 ENSDART00000149364
interleukin 23 receptor
chr15_-_33965440 0.67 ENSDART00000163841
lipolysis stimulated lipoprotein receptor
chr13_-_865193 0.67 ENSDART00000187053

chr18_+_31073265 0.66 ENSDART00000023539
cytochrome b-245, alpha polypeptide
chr3_-_32958505 0.66 ENSDART00000147374
ENSDART00000136919
caspase 6, apoptosis-related cysteine peptidase, like 1
chr3_+_13569806 0.66 ENSDART00000170105
si:ch73-106n3.2
chr5_+_69856153 0.66 ENSDART00000124128
ENSDART00000073663
UDP glucuronosyltransferase 2 family, polypeptide A6
chr2_-_16159203 0.66 ENSDART00000153480
vav 3 guanine nucleotide exchange factor b
chr11_-_30630628 0.65 ENSDART00000103265
zgc:158773
chr24_+_13735616 0.65 ENSDART00000184267
musculin (activated B-cell factor-1)
chr6_-_7438584 0.65 ENSDART00000053776
FK506 binding protein 11
chr1_+_57187794 0.65 ENSDART00000152485
si:dkey-27j5.9
chr13_-_45155792 0.65 ENSDART00000163556
runt-related transcription factor 3
chr3_-_22356568 0.65 ENSDART00000058507
interferon phi 2
chr6_-_27108844 0.65 ENSDART00000073883
deoxythymidylate kinase (thymidylate kinase)
chr17_-_10838434 0.65 ENSDART00000064597
lectin, galactoside binding soluble 3b
chr11_-_12198765 0.64 ENSDART00000104203
ENSDART00000128364
ENSDART00000166887
ENSDART00000041533
kertain 95
chr10_-_17501528 0.64 ENSDART00000144847
solute carrier family 2 (facilitated glucose transporter), member 11-like
chr2_-_37465517 0.64 ENSDART00000139983
si:dkey-57k2.6
chr7_+_53156810 0.63 ENSDART00000189816
cadherin 29
chr4_-_13613148 0.63 ENSDART00000067164
ENSDART00000111247
interferon regulatory factor 5
chr3_-_7990516 0.63 ENSDART00000167877
si:ch211-175l6.2
chr11_-_21304452 0.62 ENSDART00000163008
si:dkey-85p17.3
chr13_-_20381485 0.62 ENSDART00000131351
si:ch211-270n8.1
chr7_+_35229805 0.62 ENSDART00000173911
tubulin polymerization-promoting protein family member 3
chr15_-_38129845 0.62 ENSDART00000057095
si:dkey-24p1.1
chr24_-_25098719 0.62 ENSDART00000193651
pleckstrin homology-like domain, family B, member 2b
chr5_+_65991152 0.62 ENSDART00000097756
lipocalin 15
chr7_-_52417060 0.61 ENSDART00000148579
myocardial zonula adherens protein
chr16_+_1383914 0.61 ENSDART00000185089
ceramide synthase 2b
chr3_-_79366 0.61 ENSDART00000114289
zgc:165518
chr3_-_29870848 0.61 ENSDART00000186457
ribosomal protein L3
chr4_-_12795436 0.61 ENSDART00000131026
ENSDART00000075127
beta-2-microglobulin
chr9_+_50175366 0.61 ENSDART00000170352
cordon-bleu WH2 repeat protein-like 1b
chr19_+_3849378 0.60 ENSDART00000166218
ENSDART00000159228
organic solute carrier partner 1a
chr19_+_37118547 0.60 ENSDART00000103163
connexin 30.9
chr23_-_43486714 0.60 ENSDART00000169726
E2F transcription factor 1
chr1_-_55008882 0.60 ENSDART00000083572
zgc:136864
chr2_-_37862380 0.60 ENSDART00000186005
si:ch211-284o19.8
chr19_+_40350468 0.59 ENSDART00000087444
HEPACAM family member 2
chr14_-_26498196 0.59 ENSDART00000054175
ENSDART00000145625
ENSDART00000183347
ENSDART00000191084
ENSDART00000191143
SMAD family member 5
chr9_-_43082945 0.59 ENSDART00000142257
coiled-coil domain containing 141
chr7_+_4694924 0.59 ENSDART00000144873
si:ch211-225k7.3
chr3_+_55114097 0.59 ENSDART00000121686
hemoglobin beta embryonic-1.1
chr24_+_19518570 0.59 ENSDART00000056081
sulfatase 1
chr13_-_15982707 0.59 ENSDART00000186911
ENSDART00000181072
IKAROS family zinc finger 1 (Ikaros)
chr23_-_9925568 0.59 ENSDART00000081268
si:ch211-220i18.4
chr20_+_192170 0.59 ENSDART00000189675
connexin 28.8
chr25_-_14637660 0.59 ENSDART00000143666
neuron navigator 2b
chr8_+_6576940 0.58 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr2_-_16159491 0.58 ENSDART00000110059
vav 3 guanine nucleotide exchange factor b
chr24_+_38205798 0.58 ENSDART00000141532
immunoglobulin light 3 variable 1
chr22_+_18156000 0.58 ENSDART00000143483
ENSDART00000136133
nuclear receptor 2C2-associated protein
chr6_-_7769178 0.58 ENSDART00000191701
ENSDART00000149823
myosin, heavy chain 9a, non-muscle
chr22_+_6096303 0.58 ENSDART00000139276
zgc:171887
chr5_+_9360394 0.58 ENSDART00000124642

chr24_-_36680261 0.58 ENSDART00000059507
chemokine (C-C motif) receptor 10
chr2_+_36620011 0.57 ENSDART00000177428
p21 protein (Cdc42/Rac)-activated kinase 2a
chr17_+_6382275 0.57 ENSDART00000056324

chr21_+_22985078 0.56 ENSDART00000156491
lysophosphatidic acid receptor 6b
chr9_+_9296222 0.56 ENSDART00000141325
si:ch211-214p13.8
chr19_+_19786117 0.56 ENSDART00000167757
ENSDART00000163546
homeobox A1a
chr25_-_7974494 0.56 ENSDART00000171446
histidine ammonia-lyase
chr17_-_36529016 0.56 ENSDART00000025019
collectin sub-family member 11
chr18_+_27571448 0.56 ENSDART00000147886
CD82 molecule b
chr16_-_30885838 0.55 ENSDART00000131356
DENN/MADD domain containing 3b
chr23_+_10347851 0.55 ENSDART00000127667
keratin 18
chr20_+_54027943 0.55 ENSDART00000153400
ENSDART00000152961
si:dkey-241l7.3
chr22_-_10117918 0.55 ENSDART00000177475
ENSDART00000128590
retinol dehydrogenase 5 (11-cis/9-cis)
chr19_+_32856907 0.55 ENSDART00000148232
ribosomal protein L30
chr4_-_26107841 0.54 ENSDART00000172012
si:ch211-244b2.4
chr25_+_4541211 0.54 ENSDART00000129978
patatin-like phospholipase domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of runx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0006740 NADPH regeneration(GO:0006740)
0.7 3.3 GO:0003210 cardiac atrium formation(GO:0003210)
0.4 1.7 GO:0015840 urea transport(GO:0015840)
0.4 1.4 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.3 0.8 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.3 1.1 GO:0009265 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221) 2'-deoxyribonucleotide biosynthetic process(GO:0009265) deoxyribose phosphate biosynthetic process(GO:0046385)
0.2 0.6 GO:0019557 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.2 0.5 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.2 0.7 GO:0010039 response to iron ion(GO:0010039)
0.2 1.0 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.2 0.5 GO:0090435 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.2 0.8 GO:0030823 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.1 2.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.1 0.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 1.2 GO:0090594 inflammatory response to wounding(GO:0090594)
0.1 1.0 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 1.0 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.8 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.1 1.5 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.1 0.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.5 GO:0050996 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898) positive regulation of lipid catabolic process(GO:0050996)
0.1 0.4 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.6 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.7 GO:0000730 DNA recombinase assembly(GO:0000730)
0.1 0.4 GO:0070640 vitamin D3 metabolic process(GO:0070640)
0.1 0.7 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.1 0.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 0.2 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 9.3 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.1 0.6 GO:0072103 renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.1 0.3 GO:0060148 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1 0.4 GO:0008356 asymmetric cell division(GO:0008356)
0.1 0.7 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 0.5 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.5 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.6 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.1 0.3 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.1 0.3 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.1 0.9 GO:0033628 regulation of cell adhesion mediated by integrin(GO:0033628)
0.1 1.0 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.3 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.5 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.1 0.4 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.4 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 0.4 GO:1904105 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591) positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.1 0.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 1.6 GO:0030183 B cell differentiation(GO:0030183)
0.1 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.9 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.1 0.2 GO:0034398 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.2 GO:0061213 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.6 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 0.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.4 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 1.6 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.2 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.1 0.5 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.2 GO:0051099 cytidine to uridine editing(GO:0016554) positive regulation of DNA binding(GO:0043388) positive regulation of binding(GO:0051099)
0.1 0.5 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 1.4 GO:0015671 oxygen transport(GO:0015671)
0.1 0.9 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 0.3 GO:0070199 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.1 0.6 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.1 1.0 GO:0036065 fucosylation(GO:0036065)
0.1 0.3 GO:0051661 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.1 0.3 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 0.3 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.4 GO:1900117 regulation of execution phase of apoptosis(GO:1900117) negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.2 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.1 0.4 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.1 0.6 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.4 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1 0.2 GO:0046833 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833)
0.1 0.2 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.1 0.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.7 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.2 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.1 0.6 GO:0043651 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.3 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1 0.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.7 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 0.6 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.1 0.4 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 1.8 GO:0030199 collagen fibril organization(GO:0030199)
0.0 2.9 GO:0007596 blood coagulation(GO:0007596)
0.0 0.7 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.8 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.4 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.4 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.5 GO:0061718 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 5.9 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.4 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 0.4 GO:0031179 peptide modification(GO:0031179)
0.0 0.3 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.6 GO:0019730 antimicrobial humoral response(GO:0019730)
0.0 2.2 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.3 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.2 GO:0090497 mesenchymal cell migration(GO:0090497)
0.0 0.1 GO:0050968 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 3.7 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 1.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:1903504 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0060420 regulation of heart growth(GO:0060420)
0.0 0.3 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.2 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 1.0 GO:0043049 otic placode formation(GO:0043049)
0.0 1.0 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.4 GO:0030719 P granule organization(GO:0030719)
0.0 1.0 GO:0019835 cytolysis(GO:0019835)
0.0 0.4 GO:0042026 protein refolding(GO:0042026)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.2 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.4 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.1 GO:0033512 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.0 0.4 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.3 GO:0070874 negative regulation of peptidyl-serine phosphorylation(GO:0033137) negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.2 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.6 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.2 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.5 GO:0006956 complement activation(GO:0006956) protein activation cascade(GO:0072376)
0.0 0.9 GO:0007631 feeding behavior(GO:0007631)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 1.5 GO:0031638 zymogen activation(GO:0031638)
0.0 0.1 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.4 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 1.0 GO:0007259 JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0 0.3 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 0.2 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.3 GO:0034377 plasma lipoprotein particle assembly(GO:0034377) protein-lipid complex assembly(GO:0065005)
0.0 0.1 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.7 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.7 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.0 0.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.0 0.6 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0009204 deoxyribonucleoside triphosphate catabolic process(GO:0009204)
0.0 0.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.5 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.1 GO:0035739 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) negative regulation of alpha-beta T cell proliferation(GO:0046642) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.2 GO:2000105 positive regulation of DNA-dependent DNA replication(GO:2000105)
0.0 1.2 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.7 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.1 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 1.4 GO:0051607 defense response to virus(GO:0051607)
0.0 1.7 GO:0009617 response to bacterium(GO:0009617)
0.0 1.4 GO:0060348 bone development(GO:0060348)
0.0 0.8 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.0 0.2 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.1 GO:0034969 histone arginine methylation(GO:0034969)
0.0 0.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0001886 endothelial cell morphogenesis(GO:0001886) negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.4 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.5 GO:0002685 regulation of leukocyte migration(GO:0002685)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:1901998 toxin transport(GO:1901998)
0.0 0.5 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 1.8 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.3 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) serotonin receptor signaling pathway(GO:0007210)
0.0 0.1 GO:0097241 cannabinoid signaling pathway(GO:0038171) hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.1 GO:1904086 regulation of epiboly involved in gastrulation with mouth forming second(GO:1904086)
0.0 0.1 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.5 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.5 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.7 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.0 GO:0032205 negative regulation of telomere maintenance(GO:0032205)
0.0 0.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.0 GO:0032263 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.1 GO:0016117 tetraterpenoid metabolic process(GO:0016108) tetraterpenoid biosynthetic process(GO:0016109) carotenoid metabolic process(GO:0016116) carotenoid biosynthetic process(GO:0016117) xanthophyll metabolic process(GO:0016122) xanthophyll biosynthetic process(GO:0016123) zeaxanthin metabolic process(GO:1901825) zeaxanthin biosynthetic process(GO:1901827)
0.0 1.2 GO:0002768 immune response-regulating cell surface receptor signaling pathway(GO:0002768)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.0 GO:1901052 sarcosine metabolic process(GO:1901052)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.1 GO:0010165 response to X-ray(GO:0010165)
0.0 0.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0045117 azole transport(GO:0045117)
0.0 0.6 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.3 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.0 0.2 GO:0009409 response to cold(GO:0009409)
0.0 0.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.6 GO:0060326 cell chemotaxis(GO:0060326)
0.0 0.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.0 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.0 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.4 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.1 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.3 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.5 GO:0043542 endothelial cell migration(GO:0043542)
0.0 0.1 GO:0030325 adrenal gland development(GO:0030325)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.2 0.7 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.2 1.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.5 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 0.5 GO:0019815 B cell receptor complex(GO:0019815)
0.1 1.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.5 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 1.7 GO:0070187 telosome(GO:0070187)
0.1 0.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.3 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.1 GO:0005922 connexon complex(GO:0005922)
0.1 0.3 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.3 GO:0043614 multi-eIF complex(GO:0043614)
0.1 0.3 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 0.7 GO:0031526 brush border membrane(GO:0031526)
0.1 0.6 GO:0016234 inclusion body(GO:0016234)
0.1 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.3 GO:0030689 Noc complex(GO:0030689)
0.1 0.6 GO:0001772 immunological synapse(GO:0001772)
0.1 0.6 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.1 0.5 GO:0005784 Sec61 translocon complex(GO:0005784)
0.1 0.6 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.2 GO:0034709 methylosome(GO:0034709)
0.1 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.3 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 1.0 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.0 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.5 GO:0070938 contractile ring(GO:0070938)
0.1 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.5 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0061702 inflammasome complex(GO:0061702)
0.0 1.1 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0070390 transcription export complex 2(GO:0070390)
0.0 2.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 6.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0034518 RNA cap binding complex(GO:0034518)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.8 GO:0043186 P granule(GO:0043186)
0.0 2.5 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.9 GO:0005581 collagen trimer(GO:0005581)
0.0 1.0 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.9 GO:0008305 integrin complex(GO:0008305)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 1.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 19.7 GO:0005615 extracellular space(GO:0005615)
0.0 0.0 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.1 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.0 2.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.6 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.0 GO:0031213 RSF complex(GO:0031213)
0.0 0.4 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0045335 phagocytic vesicle(GO:0045335)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.7 2.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.3 1.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.3 3.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 0.8 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.2 2.0 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.2 0.7 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.2 0.6 GO:0009041 uridylate kinase activity(GO:0009041)
0.2 0.6 GO:0042806 fucose binding(GO:0042806)
0.2 0.5 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174)
0.2 1.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 1.4 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.4 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.7 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.6 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 1.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.4 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.6 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 0.4 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.1 0.5 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.1 0.3 GO:0046978 TAP1 binding(GO:0046978)
0.1 0.8 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.5 GO:0060182 apelin receptor activity(GO:0060182)
0.1 2.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 4.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.3 GO:0032138 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.1 0.3 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.1 1.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.3 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 0.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.3 GO:0045545 syndecan binding(GO:0045545)
0.1 1.1 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.6 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 1.0 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.1 0.2 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.2 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.1 0.3 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.1 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.0 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 1.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.9 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.3 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.1 0.2 GO:0003721 telomerase RNA reverse transcriptase activity(GO:0003721)
0.1 0.8 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.1 1.4 GO:0019825 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.1 0.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.2 GO:0005549 odorant binding(GO:0005549)
0.1 0.3 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 0.4 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.4 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.2 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.3 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.1 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.2 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 5.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.8 GO:0022884 macromolecule transmembrane transporter activity(GO:0022884)
0.1 1.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.4 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.1 0.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.7 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 1.7 GO:0042923 neuropeptide binding(GO:0042923)
0.0 10.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0003872 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.0 0.3 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.4 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0042165 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.0 0.3 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.5 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.4 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.5 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 1.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 1.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.4 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity(GO:0052905)
0.0 0.2 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.1 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672)
0.0 1.0 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.5 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 1.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 1.2 GO:0031072 heat shock protein binding(GO:0031072)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 1.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 3.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 6.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.0 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.0 0.3 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0052885 retinol isomerase activity(GO:0050251) all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity(GO:0052885)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 1.5 GO:0005125 cytokine activity(GO:0005125)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 1.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.0 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.1 1.4 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 1.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 1.7 PID RAS PATHWAY Regulation of Ras family activation
0.1 1.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.7 PID EPO PATHWAY EPO signaling pathway
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.6 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.3 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 3.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 ST JNK MAPK PATHWAY JNK MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 1.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.9 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 1.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 0.9 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 1.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 1.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 0.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 3.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.8 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism