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PRJNA207719: Tissue specific transcriptome profiling

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Results for rest

Z-value: 8.36

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Transcription factors associated with rest

Gene Symbol Gene ID Gene Info
ENSDARG00000103046 Danio rerio RE1-silencing transcription factor (rest), mRNA.

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
restdr11_v1_chr14_-_52433292_52433292-0.187.7e-01Click!

Activity profile of rest motif

Sorted Z-values of rest motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_34913069 16.88 ENSDART00000007584
synaptosomal-associated protein, 25a
chr23_+_45579497 14.57 ENSDART00000110381
early growth response 4
chr17_-_12385308 13.85 ENSDART00000080927
synaptosomal-associated protein, 25b
chr15_+_36156986 13.58 ENSDART00000059791
somatostatin 1, tandem duplicate 1
chr25_-_19443421 13.44 ENSDART00000067362
cocaine- and amphetamine-regulated transcript 2
chr21_+_11468934 13.14 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr25_+_35250976 12.98 ENSDART00000003494
solute carrier family 17 (vesicular glutamate transporter), member 6a
chr16_+_46148990 12.88 ENSDART00000083919
synaptic vesicle glycoprotein 2A
chr21_+_11468642 12.79 ENSDART00000041869
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr18_+_26337869 12.41 ENSDART00000109257
si:ch211-234p18.3
chr7_+_23907692 12.34 ENSDART00000045479
synaptotagmin IV
chr25_-_22639133 12.15 ENSDART00000073583
immunoglobulin superfamily containing leucine-rich repeat 2
chr7_+_40228422 11.89 ENSDART00000052222
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr3_+_33340939 11.14 ENSDART00000128786
peptide YYa
chr21_-_42100471 11.07 ENSDART00000166148
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr19_-_19339285 10.78 ENSDART00000158413
ENSDART00000170479
chondroitin sulfate proteoglycan 5b
chr10_+_23022263 10.68 ENSDART00000138955
si:dkey-175g6.2
chr5_-_29643381 10.55 ENSDART00000034849
glutamate receptor, ionotropic, N-methyl D-aspartate 1b
chr25_-_31863374 10.55 ENSDART00000028338
secretory carrier membrane protein 5a
chr20_+_27020201 10.51 ENSDART00000126919
ENSDART00000016014
chromogranin A
chr9_-_34915351 10.51 ENSDART00000100728
ENSDART00000139608
UPF3A, regulator of nonsense mediated mRNA decay
chr6_-_30210378 10.19 ENSDART00000157359
ENSDART00000113924
leucine rich repeat containing 7
chr22_-_25033105 10.11 ENSDART00000124220
neuronal pentraxin receptor b
chr5_-_29643930 10.05 ENSDART00000161250
glutamate receptor, ionotropic, N-methyl D-aspartate 1b
chr4_-_5302866 10.02 ENSDART00000138590
si:ch211-214j24.9
chr6_+_41255485 9.82 ENSDART00000042683
ENSDART00000186013
Ca2+-dependent activator protein for secretion b
chr1_+_10720294 9.48 ENSDART00000139387
ATPase Na+/K+ transporting subunit beta 1b
chr20_+_38724575 9.39 ENSDART00000015095
ENSDART00000152972
urotensin 1
chr23_-_17657348 9.18 ENSDART00000054736
basic helix-loop-helix family, member e23
chr7_+_26224211 8.81 ENSDART00000173999
VGF nerve growth factor inducible
chr4_-_5302162 8.67 ENSDART00000177099
si:ch211-214j24.9
chr3_+_33341640 8.41 ENSDART00000186352
peptide YYa
chr7_-_32833153 8.37 ENSDART00000099871
ENSDART00000099872
solute carrier family 17 (vesicular glutamate transporter), member 6b
chr12_+_24342303 8.36 ENSDART00000111239
neurexin 1a
chr20_+_19212962 8.32 ENSDART00000063706
fibronectin type III domain containing 4a
chr10_+_25219728 8.15 ENSDART00000193829
glutamate receptor, metabotropic 5a
chr5_-_26093945 8.01 ENSDART00000010199
ENSDART00000145096
family with sequence similarity 219, member Ab
chr18_+_28988373 7.78 ENSDART00000018685
synaptotagmin IXa
chr21_-_17482465 7.76 ENSDART00000004548
BarH-like homeobox 1b
chr18_+_36806545 7.72 ENSDART00000098958
tetratricopeptide repeat domain 9B
chr19_-_42244358 7.65 ENSDART00000102697
cocaine- and amphetamine-regulated transcript 4
chr13_+_23282549 7.63 ENSDART00000101134
KH domain containing, RNA binding, signal transduction associated 2
chr20_+_45741566 7.51 ENSDART00000113454
chromogranin B
chr12_+_24561832 7.45 ENSDART00000088159
neurexin 1a
chr9_-_27649406 7.17 ENSDART00000181270
ENSDART00000187112
syntaxin binding protein 5-like
chr10_-_26793448 7.16 ENSDART00000141955
MCF.2 cell line derived transforming sequence b
chr12_-_19862912 7.00 ENSDART00000145788
shisa family member 9a
chr10_+_21588002 6.96 ENSDART00000100596
protocadherin 1 alpha 6
chr10_-_36927594 6.94 ENSDART00000162046
seizure related 6 homolog a
chr23_-_30785382 6.79 ENSDART00000136156
ENSDART00000131285
myelin transcription factor 1a
chr5_-_29750377 6.71 ENSDART00000051474
BarH-like homeobox 1a
chr23_+_35759843 6.66 ENSDART00000047082
ganglioside induced differentiation associated protein 1-like 1
chr7_-_69521481 6.62 ENSDART00000148465
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr23_+_40452157 6.35 ENSDART00000113106
ENSDART00000140136
SOGA family member 3b
chr19_-_43552252 6.25 ENSDART00000138308
G protein-coupled receptor 186
chr14_-_2032753 6.24 ENSDART00000111335
protocadherin 2 gamma 5
chr3_-_37476475 6.18 ENSDART00000148107
si:ch211-278a6.1
chr1_+_54911458 6.14 ENSDART00000089603
golgin A7 family, member Ba
chr7_-_52876683 6.08 ENSDART00000172910
microtubule-associated protein 1Aa
chr5_-_32092856 5.88 ENSDART00000086181
ENSDART00000181677
calcium binding protein 7b
chr15_+_24212847 5.79 ENSDART00000155502
seizure related 6 homolog b
chr6_-_43092175 5.73 ENSDART00000084389
leucine rich repeat neuronal 1
chr6_+_21740672 5.72 ENSDART00000193734
lipoma HMGIC fusion partner-like 4a
chr17_-_10249095 5.68 ENSDART00000159963
somatostatin receptor 1a
chr14_-_1987121 5.61 ENSDART00000135733
protocadherin 2 gamma 5
chr21_+_6751405 5.61 ENSDART00000037265
ENSDART00000146371
olfactomedin 1b
chr14_-_1998501 5.57 ENSDART00000189052
protocadherin 2 gamma 5
chr23_+_28693278 5.57 ENSDART00000078148
structural maintenance of chromosomes 1A
chr17_-_21617618 5.46 ENSDART00000109031
G protein-coupled receptor 26
chr23_+_41800052 5.28 ENSDART00000141484
prodynorphin
chr6_+_43903209 5.14 ENSDART00000006435
G protein-coupled receptor 27
chr14_-_2264494 5.11 ENSDART00000191149
protocadherin 2 alpha b 9
chr7_-_31940590 5.06 ENSDART00000131009
brain-derived neurotrophic factor
chr18_-_44611252 4.94 ENSDART00000173095
sprouty-related, EVH1 domain containing 3
chr18_+_660578 4.93 ENSDART00000161203
si:dkey-205h23.2
chr7_+_59739164 4.92 ENSDART00000110412
G protein-coupled receptor 78b
chr14_-_32486757 4.73 ENSDART00000148830
MCF.2 cell line derived transforming sequence a
chr23_+_30859086 4.71 ENSDART00000053661
zgc:198371
chr14_-_1963369 4.66 ENSDART00000125521
protocadherin 2 gamma 5
chr10_+_21807497 4.59 ENSDART00000164634
protocadherin 1 gamma 32
chr1_-_38538284 4.47 ENSDART00000009777
glycine receptor, alpha 3
chr14_-_2267515 4.40 ENSDART00000180988
ENSDART00000130712
protocadherin 2 alpha a 15
chr11_+_19780717 4.39 ENSDART00000157394
Ca2+-dependent activator protein for secretion a
chr20_+_41640687 4.20 ENSDART00000138686
family with sequence similarity 184, member A
chr6_-_31336317 4.20 ENSDART00000193927
DnaJ (Hsp40) homolog, subfamily C, member 6
chr21_+_6751760 3.92 ENSDART00000135914
olfactomedin 1b
chr11_+_19781053 3.80 ENSDART00000029680
ENSDART00000182743
Ca2+-dependent activator protein for secretion a
chr17_+_19630272 3.79 ENSDART00000104895
regulator of G protein signaling 7a
chr14_-_2004291 3.77 ENSDART00000114039
protocadherin 2 gamma 5
chr14_-_2193248 3.72 ENSDART00000128659
protocadherin 2 alpha b 10
chr9_-_31915423 3.58 ENSDART00000060051
fibroblast growth factor 14
chr11_+_33426510 3.43 ENSDART00000163106
contactin associated protein-like 5 like
chr12_+_19305390 3.16 ENSDART00000183987
ENSDART00000066391
casein kinase 1, epsilon
chr13_+_25846528 2.93 ENSDART00000087426
B cell CLL/lymphoma 11Aa
chr19_+_26718074 2.80 ENSDART00000134455
zgc:100906
chr7_+_17229980 2.68 ENSDART00000184910
solute carrier family 6 (neurotransmitter transporter), member 5
chr3_-_44753325 2.50 ENSDART00000074543
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr7_-_30087048 2.47 ENSDART00000112743
neuromedin Bb
chr13_-_45811137 2.47 ENSDART00000190512
fibronectin type III domain containing 5a
chr7_+_17229282 2.31 ENSDART00000097982
solute carrier family 6 (neurotransmitter transporter), member 5
chr15_-_47841259 2.30 ENSDART00000155384
kelch repeat and BTB (POZ) domain containing 3
chr16_-_40727455 2.24 ENSDART00000162331
si:dkey-22o22.2
chr10_+_36441124 2.22 ENSDART00000185626
ubiquitin specific peptidase like 1
chr15_+_35709223 2.19 ENSDART00000155840
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2a
chr2_-_4642407 1.95 ENSDART00000162044

chr2_-_5776030 1.71 ENSDART00000133851
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2b
chr12_-_1951233 1.66 ENSDART00000005676
ENSDART00000127937
SRY (sex determining region Y)-box 9a
chr17_-_33552363 1.56 ENSDART00000154400
transmembrane protein 121Aa
chr11_+_33426254 1.49 ENSDART00000111193
contactin associated protein-like 5 like
chr10_-_29892486 1.14 ENSDART00000099983
brain-specific homeobox
chr18_+_50089000 1.03 ENSDART00000058936
secretory carrier membrane protein 5b
chr20_-_35052464 0.99 ENSDART00000037195
kinesin family member 26Bb
chr4_+_357810 0.99 ENSDART00000163436
ENSDART00000103645
transmembrane protein 181
chr1_+_12348213 0.81 ENSDART00000144920
ENSDART00000138759
ENSDART00000067082
clathrin, light chain A
chr25_-_21782435 0.66 ENSDART00000089616
base methyltransferase of 25S rRNA 2 homolog
chr11_+_77526 0.56 ENSDART00000193521

chr23_+_45910033 0.54 ENSDART00000165025
ATP-binding cassette, sub-family G (WHITE), member 2a
chr17_+_19630068 0.54 ENSDART00000182619
regulator of G protein signaling 7a
chr23_+_35650771 0.28 ENSDART00000005158
cyclin T1
chr1_+_17676745 0.25 ENSDART00000030665
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr3_-_20721064 0.22 ENSDART00000193532
speckle-type POZ protein
chr23_+_38957472 0.09 ENSDART00000193836
ATPase phospholipid transporting 9A (putative)
chr4_-_17391091 0.05 ENSDART00000056002
tyrosine hydroxylase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of rest

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.5 GO:0002792 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
2.7 8.1 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
2.7 21.4 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
2.6 46.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
2.2 11.1 GO:0070208 protein heterotrimerization(GO:0070208)
1.7 13.4 GO:0008343 adult feeding behavior(GO:0008343)
1.5 10.8 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
1.4 5.7 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
1.4 18.0 GO:1990504 dense core granule exocytosis(GO:1990504)
1.2 30.7 GO:0016082 synaptic vesicle priming(GO:0016082)
0.9 19.5 GO:0007631 feeding behavior(GO:0007631)
0.8 4.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.8 4.9 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.8 7.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.7 2.9 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.7 10.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.7 5.7 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.6 9.5 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.6 5.7 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.5 9.5 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.4 20.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.4 2.2 GO:1904867 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.4 5.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.4 6.2 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.4 10.6 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.4 10.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.3 3.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 7.2 GO:0050708 regulation of protein secretion(GO:0050708)
0.2 6.1 GO:0031114 regulation of microtubule depolymerization(GO:0031114)
0.2 2.5 GO:0046887 positive regulation of hormone secretion(GO:0046887)
0.2 5.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.2 52.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 6.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 1.1 GO:0021982 pineal gland development(GO:0021982)
0.2 5.1 GO:0033500 carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593)
0.1 12.9 GO:0006836 neurotransmitter transport(GO:0006836)
0.1 7.4 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.1 1.7 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.1 15.8 GO:0002040 sprouting angiogenesis(GO:0002040)
0.1 0.7 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 16.5 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 7.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 3.9 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.1 5.3 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 0.3 GO:0015865 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 3.2 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.1 6.3 GO:0010506 regulation of autophagy(GO:0010506)
0.0 13.6 GO:0030334 regulation of cell migration(GO:0030334)
0.0 11.9 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 6.8 GO:1904888 cranial skeletal system development(GO:1904888)
0.0 0.1 GO:0042416 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.0 34.3 GO:0006357 regulation of transcription from RNA polymerase II promoter(GO:0006357)
0.0 4.3 GO:0009968 negative regulation of signal transduction(GO:0009968)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 30.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
3.1 46.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
1.9 5.7 GO:0060077 inhibitory synapse(GO:0060077)
1.4 21.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.1 7.8 GO:0031045 dense core granule(GO:0031045)
1.1 10.5 GO:0042583 chromaffin granule(GO:0042583)
0.9 9.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.6 11.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.5 5.6 GO:0030893 meiotic cohesin complex(GO:0030893)
0.4 7.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 18.0 GO:0098978 glutamatergic synapse(GO:0098978)
0.4 11.1 GO:0032590 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.4 6.1 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.3 19.2 GO:0030141 secretory granule(GO:0030141)
0.2 13.7 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 8.1 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.2 0.5 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.2 5.3 GO:0044306 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.1 7.2 GO:0031201 SNARE complex(GO:0031201)
0.1 2.2 GO:0015030 Cajal body(GO:0015030)
0.1 17.4 GO:0099503 secretory vesicle(GO:0099503)
0.1 10.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 0.7 GO:1990130 Iml1 complex(GO:1990130)
0.1 4.5 GO:0034707 chloride channel complex(GO:0034707)
0.1 10.4 GO:0014069 postsynaptic density(GO:0014069)
0.1 6.1 GO:0043025 neuronal cell body(GO:0043025)
0.0 91.8 GO:0005576 extracellular region(GO:0005576)
0.0 10.8 GO:0045202 synapse(GO:0045202)
0.0 10.5 GO:0005730 nucleolus(GO:0005730)
0.0 0.3 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 27.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 105.2 GO:0016021 integral component of membrane(GO:0016021)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 19.5 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
2.3 46.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
1.6 21.4 GO:0005326 neurotransmitter transporter activity(GO:0005326)
1.2 8.1 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
1.0 35.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.8 11.1 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.8 30.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.7 5.7 GO:0004994 somatostatin receptor activity(GO:0004994)
0.5 4.5 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.5 9.5 GO:0001671 ATPase activator activity(GO:0001671)
0.4 2.2 GO:0032183 SUMO binding(GO:0032183)
0.4 20.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.4 7.2 GO:0045159 myosin II binding(GO:0045159)
0.4 5.3 GO:0031628 opioid receptor binding(GO:0031628)
0.4 5.1 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.4 7.6 GO:0008143 poly(A) binding(GO:0008143)
0.4 5.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.3 10.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.3 5.7 GO:0050811 GABA receptor binding(GO:0050811)
0.3 2.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 23.0 GO:0005179 hormone activity(GO:0005179)
0.1 0.5 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 6.1 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 3.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.7 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.1 0.3 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 5.0 GO:0030276 clathrin binding(GO:0030276)
0.1 11.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 58.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 6.6 GO:0015293 symporter activity(GO:0015293)
0.0 11.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 17.8 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 4.9 GO:0019901 protein kinase binding(GO:0019901)
0.0 49.1 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 7.1 GO:0008017 microtubule binding(GO:0008017)
0.0 5.6 GO:0003682 chromatin binding(GO:0003682)
0.0 10.2 GO:0005102 receptor binding(GO:0005102)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 14.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.5 12.4 PID RAS PATHWAY Regulation of Ras family activation
0.2 3.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 5.6 PID ATM PATHWAY ATM pathway
0.1 5.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.8 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.9 6.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.7 11.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.3 5.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 5.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.2 5.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 5.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 2.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 10.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 3.2 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription