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PRJNA207719: Tissue specific transcriptome profiling
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Results for rbpjb
Z-value: 1.50
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Transcription factors associated with rbpjb
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| rbpjb | dr11_v1_chr7_+_62080456_62080456 | 0.28 | 6.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_31891110 Show fit | 1.75 |
ENSDART00000173883
|
myosin binding protein C, cardiac |
|
| chr17_-_25326685 Show fit | 1.40 |
ENSDART00000082327
|
poly(A) binding protein, cytoplasmic 4 (inducible form) |
|
| chr17_-_25326296 Show fit | 1.30 |
ENSDART00000168822
|
poly(A) binding protein, cytoplasmic 4 (inducible form) |
|
| chr10_+_22782522 Show fit | 1.10 |
ENSDART00000079498
ENSDART00000145558 |
si:ch211-237l4.6 |
|
| chr24_-_37877743 Show fit | 1.10 |
ENSDART00000105658
|
transmembrane protein 204 |
|
| chr20_-_39596338 Show fit | 0.90 |
ENSDART00000023531
|
hes-related family bHLH transcription factor with YRPW motif 2 |
|
| chr4_-_74367912 Show fit | 0.86 |
ENSDART00000174199
ENSDART00000165257 |
protein tyrosine phosphatase, receptor type, b |
|
| chr25_+_6122823 Show fit | 0.78 |
ENSDART00000191824
ENSDART00000067514 |
RNA binding protein with multiple splicing 2a |
|
| chr19_-_25113660 Show fit | 0.78 |
ENSDART00000035538
|
protein tyrosine phosphatase type IVA, member 3 |
|
| chr6_-_36552844 Show fit | 0.73 |
ENSDART00000023613
|
hairy-related 6 |
Network of associatons between targets according to the STRING database.
First level regulatory network of rbpjb
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.8 | GO:0003210 | cardiac atrium formation(GO:0003210) |
| 0.0 | 1.4 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 1.0 | GO:0055008 | cardiac muscle tissue morphogenesis(GO:0055008) |
| 0.3 | 0.9 | GO:0060844 | arterial endothelial cell fate commitment(GO:0060844) |
| 0.1 | 0.9 | GO:0055016 | hypochord development(GO:0055016) |
| 0.2 | 0.8 | GO:0051145 | smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148) |
| 0.1 | 0.7 | GO:0021794 | thalamus development(GO:0021794) |
| 0.0 | 0.7 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.2 | 0.6 | GO:0060043 | regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043) |
| 0.1 | 0.6 | GO:1901998 | toxin transport(GO:1901998) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.8 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 1.0 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 0.7 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 0.4 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.4 | GO:0031970 | mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970) |
| 0.0 | 0.3 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.0 | 0.3 | GO:0099569 | presynaptic cytoskeleton(GO:0099569) |
| 0.0 | 0.2 | GO:0018444 | translation release factor complex(GO:0018444) |
| 0.0 | 0.2 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.0 | 0.1 | GO:0098826 | endoplasmic reticulum tubular network membrane(GO:0098826) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.7 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.2 | 1.8 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.0 | 1.0 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.2 | 0.7 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.0 | 0.6 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 0.6 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.1 | 0.4 | GO:0019863 | IgE binding(GO:0019863) immunoglobulin binding(GO:0019865) |
| 0.0 | 0.4 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.0 | 0.4 | GO:0015002 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.4 | GO:0019003 | GDP binding(GO:0019003) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.8 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.2 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 0.7 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.6 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 0.3 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.1 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 0.1 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.0 | 0.0 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |