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PRJNA207719: Tissue specific transcriptome profiling

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Results for pou4f2

Z-value: 1.69

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Transcription factors associated with pou4f2

Gene Symbol Gene ID Gene Info
pou4f2
ENSDARG00000069737 POU class 4 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou4f2dr11_v1_chr1_+_36437585_364375850.894.3e-02Click!

Activity profile of pou4f2 motif

Sorted Z-values of pou4f2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_15433518 2.14 ENSDART00000026180
fabp7a
fatty acid binding protein 7, brain, a
chr17_+_15433671 2.06 ENSDART00000149568
fabp7a
fatty acid binding protein 7, brain, a
chr7_+_73630751 1.95 ENSDART00000159745
PCP4L1
si:dkey-46i9.1
chr16_+_29303971 1.75 ENSDART00000087149
hapln2
hyaluronan and proteoglycan link protein 2
chr8_+_16025554 1.69 ENSDART00000110171
elavl4
ELAV like neuron-specific RNA binding protein 4
chr6_+_27146671 1.67 ENSDART00000156792
kif1aa
kinesin family member 1Aa
chr2_-_21082695 1.61 ENSDART00000032502
nebl
nebulette
chr19_-_31402429 1.57 ENSDART00000137292
tmem106bb
transmembrane protein 106Bb
chr5_+_37966505 1.55 ENSDART00000127648
pafah1b2
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2
chr19_-_32641725 1.52 ENSDART00000165006
ENSDART00000188185
hpca
hippocalcin
chr12_-_35787801 1.47 ENSDART00000171682
aatkb
apoptosis-associated tyrosine kinase b
chr2_-_40135942 1.42 ENSDART00000176951
ENSDART00000098632
ENSDART00000148563
ENSDART00000149895
epha4a
eph receptor A4a
chr16_-_12173554 1.37 ENSDART00000110567
ENSDART00000155935
clstn3
calsyntenin 3
chr16_-_12173399 1.36 ENSDART00000142574
clstn3
calsyntenin 3
chr18_-_1185772 1.34 ENSDART00000143245
nptnb
neuroplastin b
chr25_-_13842618 1.26 ENSDART00000160258
mapk8ip1a
mitogen-activated protein kinase 8 interacting protein 1a
chr7_+_25059845 1.25 ENSDART00000077215
ppp2r5b
protein phosphatase 2, regulatory subunit B', beta
chr4_-_1360495 1.24 ENSDART00000164623
ptn
pleiotrophin
chr17_+_51499789 1.21 ENSDART00000187701
CABZ01067581.1

chr4_-_1801519 1.16 ENSDART00000188604
ENSDART00000135749
nudt4b
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr9_-_32753535 1.15 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr14_-_31465905 1.15 ENSDART00000173108
gpc3
glypican 3
chr7_-_18416741 1.11 ENSDART00000097882
sstr1b
somatostatin receptor 1b
chr16_-_26074529 1.10 ENSDART00000148653
ENSDART00000148923
tmem145
transmembrane protein 145
chr11_-_37509001 1.05 ENSDART00000109753
bsnb
bassoon (presynaptic cytomatrix protein) b
chr20_+_41756996 1.05 ENSDART00000186393
fam184a
family with sequence similarity 184, member A
chr23_-_28141419 1.04 ENSDART00000133039
tac3a
tachykinin 3a
chr17_+_8183393 1.03 ENSDART00000155957
tulp4b
tubby like protein 4b
chr23_-_15284757 1.00 ENSDART00000139135
sulf2b
sulfatase 2b
chr6_-_12172424 0.99 ENSDART00000109344
tanc1a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr16_+_30301539 0.99 ENSDART00000186018
LO017848.1

chr2_+_50608099 0.98 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr20_-_18736281 0.97 ENSDART00000142837
enpp5
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr7_+_25915089 0.96 ENSDART00000173648
hmgb3a
high mobility group box 3a
chr19_-_5103313 0.95 ENSDART00000037007
tpi1a
triosephosphate isomerase 1a
chr18_+_783936 0.93 ENSDART00000193357
rpp25b
ribonuclease P and MRP subunit p25, b
chr5_+_44064764 0.90 ENSDART00000143843
si:dkey-84j12.1
si:dkey-84j12.1
chr13_-_14487524 0.89 ENSDART00000141103
gfra4a
GDNF family receptor alpha 4a
chr1_+_25801648 0.88 ENSDART00000129471
gucy1b1
guanylate cyclase 1 soluble subunit beta 1
chr18_+_34362608 0.87 ENSDART00000131478
kcnab1a
potassium voltage-gated channel, shaker-related subfamily, beta member 1 a
chr1_-_53756851 0.86 ENSDART00000122445
akt3b
v-akt murine thymoma viral oncogene homolog 3b
chr15_+_45994123 0.86 ENSDART00000124704
lrfn1
leucine rich repeat and fibronectin type III domain containing 1
chr24_-_21923930 0.86 ENSDART00000131944
tagln3b
transgelin 3b
chr2_+_29249204 0.85 ENSDART00000168957
cdh18a
cadherin 18, type 2a
chr9_-_43538328 0.84 ENSDART00000140526
znf385b
zinc finger protein 385B
chr2_+_12302527 0.81 ENSDART00000091298
ENSDART00000182569
arhgap21b
Rho GTPase activating protein 21b
chr18_-_40509006 0.79 ENSDART00000021372
chrna5
cholinergic receptor, nicotinic, alpha 5
chr1_-_22512063 0.78 ENSDART00000031546
ENSDART00000190987
chrna6
cholinergic receptor, nicotinic, alpha 6
chr5_-_63515210 0.77 ENSDART00000022348
prdm12b
PR domain containing 12b
chr17_+_11675362 0.76 ENSDART00000157911
kif26ba
kinesin family member 26Ba
chr11_+_38280454 0.76 ENSDART00000171496
CDK18
si:dkey-166c18.1
chr17_-_12926456 0.75 ENSDART00000044126
INSM2
INSM transcriptional repressor 2
chr21_+_28958471 0.75 ENSDART00000144331
ENSDART00000005929
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr5_+_51443009 0.74 ENSDART00000083350
rasgrf2b
Ras protein-specific guanine nucleotide-releasing factor 2b
chr7_+_19552381 0.73 ENSDART00000169060
si:ch211-212k18.5
si:ch211-212k18.5
chr4_-_23908802 0.72 ENSDART00000138873
celf2
cugbp, Elav-like family member 2
chr6_+_54187643 0.71 ENSDART00000056830
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr3_+_33341640 0.70 ENSDART00000186352
pyya
peptide YYa
chr8_+_44714336 0.67 ENSDART00000145801
elmod3
ELMO/CED-12 domain containing 3
chr18_-_2433011 0.66 ENSDART00000181922
ENSDART00000193276
CR769778.1

chr1_-_50859053 0.66 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr14_+_25817628 0.64 ENSDART00000047680
glra1
glycine receptor, alpha 1
chr3_-_23406964 0.63 ENSDART00000114723
rapgefl1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr12_+_32729470 0.63 ENSDART00000175712
rbfox3a
RNA binding fox-1 homolog 3a
chr6_+_39184236 0.62 ENSDART00000156187
tac3b
tachykinin 3b
chr25_+_6186823 0.57 ENSDART00000153526
oaz2a
ornithine decarboxylase antizyme 2a
chr5_+_42381273 0.57 ENSDART00000142387
pimr58
Pim proto-oncogene, serine/threonine kinase, related 58
chr10_+_40284003 0.56 ENSDART00000062795
ENSDART00000193825
ENSDART00000113582
git2b
G protein-coupled receptor kinase interacting ArfGAP 2b
chr16_+_25011994 0.56 ENSDART00000157312
znf1035
zinc finger protein 1035
chr2_-_30784198 0.54 ENSDART00000182523
ENSDART00000147355
rgs20
regulator of G protein signaling 20
chr3_-_33574576 0.53 ENSDART00000184881
CR847537.1

chr22_+_10698549 0.51 ENSDART00000081228
abhd14a
abhydrolase domain containing 14A
chr13_+_36622100 0.47 ENSDART00000133198
si:ch211-67f24.7
si:ch211-67f24.7
chr5_+_17624463 0.46 ENSDART00000183869
ENSDART00000081064
fbrsl1
fibrosin-like 1
chr17_-_29902187 0.46 ENSDART00000009104
esrrb
estrogen-related receptor beta
chr7_+_32369026 0.44 ENSDART00000169588
lgr4
leucine-rich repeat containing G protein-coupled receptor 4
chr19_-_5103141 0.44 ENSDART00000150952
tpi1a
triosephosphate isomerase 1a
chr10_+_38775959 0.43 ENSDART00000192990
dscama
Down syndrome cell adhesion molecule a
chr8_+_17884569 0.42 ENSDART00000134660
slc44a5b
solute carrier family 44, member 5b
chr10_+_38775408 0.41 ENSDART00000125045
dscama
Down syndrome cell adhesion molecule a
chr14_+_45883687 0.40 ENSDART00000114790
flrt1b
fibronectin leucine rich transmembrane protein 1b
chr13_+_31177934 0.40 ENSDART00000144568
ptpn20
protein tyrosine phosphatase, non-receptor type 20
chr13_-_37109987 0.39 ENSDART00000136750
syne2b
spectrin repeat containing, nuclear envelope 2b
chr2_+_29249561 0.39 ENSDART00000099157
cdh18a
cadherin 18, type 2a
chr5_-_72415578 0.38 ENSDART00000029014
pax8
paired box 8
chr9_-_29003245 0.38 ENSDART00000183391
ENSDART00000188836
ptpn4a
protein tyrosine phosphatase, non-receptor type 4a
chr24_+_19593197 0.35 ENSDART00000151923
slco5a1a
solute carrier organic anion transporter family member 5A1a
chr17_+_26352372 0.35 ENSDART00000155177
grid1a
glutamate receptor, ionotropic, delta 1a
chr14_-_7306983 0.33 ENSDART00000158914
si:ch211-51f19.1
si:ch211-51f19.1
chr9_+_29430432 0.32 ENSDART00000125632
uggt2
UDP-glucose glycoprotein glucosyltransferase 2
chr8_+_12951155 0.32 ENSDART00000081601
cept1a
choline/ethanolamine phosphotransferase 1a
chr9_+_21793565 0.32 ENSDART00000134915
rev1
REV1, polymerase (DNA directed)
chr2_+_23006792 0.31 ENSDART00000027782
mknk2a
MAP kinase interacting serine/threonine kinase 2a
chr7_+_53498152 0.31 ENSDART00000184497
znf609b
zinc finger protein 609b
chr3_+_56276346 0.31 ENSDART00000157770
PRKCA
si:ch73-374l24.1
chr3_-_61362398 0.30 ENSDART00000156177
si:dkey-111k8.3
si:dkey-111k8.3
chr18_-_15551360 0.24 ENSDART00000159915
ENSDART00000172690
ppfibp1b
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr16_+_25107344 0.23 ENSDART00000033211
zgc:66448
zgc:66448
chr8_-_40555340 0.23 ENSDART00000163348
NPC1L1
NPC1 like intracellular cholesterol transporter 1
chr12_-_10409961 0.23 ENSDART00000149521
ENSDART00000052001
eef2k
eukaryotic elongation factor 2 kinase
chr19_+_9459050 0.23 ENSDART00000186419
si:ch211-288g17.3
si:ch211-288g17.3
chr11_-_3860199 0.22 ENSDART00000082420
gata2a
GATA binding protein 2a
chr7_-_33960170 0.21 ENSDART00000180766
skor1a
SKI family transcriptional corepressor 1a
chr14_+_28486213 0.21 ENSDART00000161852
stag2b
stromal antigen 2b
chr4_+_11695979 0.21 ENSDART00000137736
mkln1
muskelin 1, intracellular mediator containing kelch motifs
chr12_+_24952902 0.18 ENSDART00000189086
ENSDART00000014868
calm3a
calmodulin 3a (phosphorylase kinase, delta)
chr24_-_6628359 0.17 ENSDART00000169731
arhgap21a
Rho GTPase activating protein 21a
chr2_-_9818640 0.17 ENSDART00000139499
ENSDART00000165548
ENSDART00000012442
ENSDART00000046587
ap2m1b
adaptor-related protein complex 2, mu 1 subunit, b
chr11_-_3860534 0.17 ENSDART00000082425
gata2a
GATA binding protein 2a
chr3_-_32169754 0.16 ENSDART00000179010
tnnt1
troponin T type 1 (skeletal, slow)
chr17_+_6765621 0.16 ENSDART00000156637
ENSDART00000007622
afg1la
AFG1 like ATPase a
chr21_-_25612658 0.15 ENSDART00000115276
fibpb
fibroblast growth factor (acidic) intracellular binding protein b
chr13_+_31180084 0.14 ENSDART00000133774
ptpn20
protein tyrosine phosphatase, non-receptor type 20
chr1_+_10318089 0.13 ENSDART00000029774
pip4p1b
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr9_-_32158288 0.12 ENSDART00000037182
ankrd44
ankyrin repeat domain 44
chr8_-_4327473 0.11 ENSDART00000134378
cux2b
cut-like homeobox 2b
chr20_+_13781779 0.11 ENSDART00000142999
ENSDART00000152471
lpgat1
lysophosphatidylglycerol acyltransferase 1
chr6_-_40466861 0.11 ENSDART00000062724
crbn
cereblon
chr10_+_38526496 0.10 ENSDART00000144329
acer3
alkaline ceramidase 3
chr8_-_17167819 0.10 ENSDART00000135042
ENSDART00000143920
mrps36
mitochondrial ribosomal protein S36
chr15_-_5720583 0.10 ENSDART00000158034
ENSDART00000190332
ENSDART00000109599
urb1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr11_+_44502410 0.09 ENSDART00000172998
ero1b
endoplasmic reticulum oxidoreductase beta
chr2_+_16696052 0.09 ENSDART00000022356
ENSDART00000164329
ppp1r7
protein phosphatase 1, regulatory (inhibitor) subunit 7
chr7_-_69185124 0.08 ENSDART00000182217
ENSDART00000191359
usp10
ubiquitin specific peptidase 10
chr6_+_4033832 0.07 ENSDART00000159952
sema5bb
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Bb
chr14_-_32959851 0.07 ENSDART00000075157
chic1
cysteine-rich hydrophobic domain 1
chr3_-_30434016 0.06 ENSDART00000150958
lrrc4ba
leucine rich repeat containing 4Ba
chr3_+_45687266 0.06 ENSDART00000131652
gpr146
G protein-coupled receptor 146
chr14_+_46287296 0.06 ENSDART00000183620
cabp2b
calcium binding protein 2b
chr11_+_3585934 0.05 ENSDART00000055694
cdab
cytidine deaminase b
chr17_-_49438873 0.05 ENSDART00000004424
znf292a
zinc finger protein 292a
chr13_-_33194647 0.03 ENSDART00000134383
trip11
thyroid hormone receptor interactor 11
chr9_-_19699728 0.03 ENSDART00000166780
si:ch211-141e20.2
si:ch211-141e20.2
chr9_+_38088331 0.03 ENSDART00000123749
cacnb4a
calcium channel, voltage-dependent, beta 4a subunit
chr21_-_38853737 0.03 ENSDART00000184100
tlr22
toll-like receptor 22
chr10_+_2899108 0.02 ENSDART00000147031
erap1a
endoplasmic reticulum aminopeptidase 1a
chr13_+_35339182 0.02 ENSDART00000019323
jag1b
jagged 1b
chr21_+_36623162 0.02 ENSDART00000027459
grk6
G protein-coupled receptor kinase 6
chr3_-_30384353 0.01 ENSDART00000186832
lrrc4ba
leucine rich repeat containing 4Ba
chr24_-_41267184 0.01 ENSDART00000063504
xylb
xylulokinase homolog (H. influenzae)
chr10_-_35103208 0.01 ENSDART00000192734
zgc:110006
zgc:110006
chr8_+_52314542 0.00 ENSDART00000013059
ENSDART00000125241
dbnlb
drebrin-like b

Network of associatons between targets according to the STRING database.

First level regulatory network of pou4f2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.3 1.7 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 2.7 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 1.1 GO:0021742 abducens nucleus development(GO:0021742)
0.3 0.8 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 1.5 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.2 1.2 GO:1901908 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 0.9 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.2 0.9 GO:1901017 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.2 0.6 GO:0071361 cellular response to ethanol(GO:0071361)
0.2 1.4 GO:0003404 optic vesicle morphogenesis(GO:0003404)
0.1 1.1 GO:0060976 coronary vasculature development(GO:0060976)
0.1 0.4 GO:1902893 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.1 1.0 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 1.6 GO:0032418 lysosome localization(GO:0032418)
0.1 0.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 2.2 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 0.4 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.1 0.8 GO:0035094 response to nicotine(GO:0035094)
0.1 1.0 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 1.2 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 1.1 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.1 0.8 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.4 GO:0034672 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.0 0.7 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.7 GO:0007631 feeding behavior(GO:0007631)
0.0 0.6 GO:0006595 polyamine metabolic process(GO:0006595)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.8 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 1.2 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 1.3 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.0 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.2 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.8 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.0 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 0.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 2.3 GO:0043204 perikaryon(GO:0043204)
0.0 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 2.4 GO:0005871 kinesin complex(GO:0005871)
0.0 1.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 4.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.6 GO:0005925 focal adhesion(GO:0005925)
0.0 1.4 GO:0005769 early endosome(GO:0005769)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.3 4.2 GO:0005504 fatty acid binding(GO:0005504)
0.3 0.8 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 1.2 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.6 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.7 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.1 1.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.8 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.6 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 2.2 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 1.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.2 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 0.3 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 1.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 1.0 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 1.0 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.9 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.2 GO:0045296 cadherin binding(GO:0045296)
0.0 1.2 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 1.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 1.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway