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PRJNA207719: Tissue specific transcriptome profiling

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Results for pou2f3

Z-value: 1.39

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Transcription factors associated with pou2f3

Gene Symbol Gene ID Gene Info
ENSDARG00000052387 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou2f3dr11_v1_chr5_+_58550291_585502910.089.0e-01Click!

Activity profile of pou2f3 motif

Sorted Z-values of pou2f3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_22476742 1.33 ENSDART00000078759
ENSDART00000130101
ENSDART00000137220
ENSDART00000133065
ENSDART00000147348
LIM domain binding 3a
chr18_-_20869175 1.28 ENSDART00000090079
synemin, intermediate filament protein
chr6_+_6924637 1.16 ENSDART00000065551
ENSDART00000151393
sterile alpha motif and leucine zipper containing kinase AZK
chr25_+_3058924 0.96 ENSDART00000029580
ferritin, heavy polypeptide 1b
chr1_+_25801648 0.79 ENSDART00000129471
guanylate cyclase 1 soluble subunit beta 1
chr10_+_39084354 0.78 ENSDART00000158245
si:ch73-1a9.3
chr23_+_22200467 0.71 ENSDART00000025414
solute carrier family 2 (facilitated glucose transporter), member 1a
chr4_+_4509996 0.67 ENSDART00000028694
glucosamine (N-acetyl)-6-sulfatase a
chr20_+_572037 0.59 ENSDART00000028062
ENSDART00000152736
ENSDART00000031759
ENSDART00000162198
SET and MYND domain containing 2b
chr19_-_7450796 0.51 ENSDART00000104750
MLLT11, transcription factor 7 cofactor
chr6_-_20875111 0.51 ENSDART00000115118
ENSDART00000159916
tensin 1a
chr3_+_39566999 0.51 ENSDART00000146867
aldolase a, fructose-bisphosphate, a
chr11_+_37275448 0.51 ENSDART00000161423
cysteine-rich with EGF-like domains 1a
chr13_-_2189761 0.48 ENSDART00000166255
muscular LMNA-interacting protein
chr25_+_35019693 0.47 ENSDART00000046218
filamin C, gamma a (actin binding protein 280)
chr24_+_792429 0.46 ENSDART00000082523
inositol(myo)-1(or 4)-monophosphatase 2
chr13_-_2215213 0.46 ENSDART00000129773
muscular LMNA-interacting protein
chr23_-_35066816 0.45 ENSDART00000168731
ENSDART00000163731

chr5_-_25583125 0.44 ENSDART00000031665
ENSDART00000145353
annexin A1a
chr20_-_43750771 0.44 ENSDART00000100605
tetratricopeptide repeat domain 32
chr1_+_51039558 0.43 ENSDART00000024743
dpy-30 histone methyltransferase complex regulatory subunit
chr16_-_42523744 0.43 ENSDART00000017185
T-box 20
chr5_-_25582721 0.42 ENSDART00000123986
annexin A1a
chr19_-_25114701 0.42 ENSDART00000149035
protein tyrosine phosphatase type IVA, member 3
chr25_+_35189555 0.42 ENSDART00000044453
anoctamin 5a
chr1_-_38815361 0.41 ENSDART00000148790
ENSDART00000148572
ENSDART00000149080
ankyrin repeat and SOCS box containing 5b
chr11_-_36341028 0.41 ENSDART00000146093
sortilin 1a
chr25_+_14017609 0.40 ENSDART00000129105
ENSDART00000125733
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr10_-_22918214 0.39 ENSDART00000163908
ribonuclease, RNase K b
chr7_-_18168493 0.39 ENSDART00000127428
pellino E3 ubiquitin protein ligase family member 3
chr11_-_36341189 0.39 ENSDART00000159752
sortilin 1a
chr3_-_50865079 0.38 ENSDART00000164295
peripheral myelin protein 22a
chr25_-_13490744 0.35 ENSDART00000056721
lactate dehydrogenase D
chr15_-_43284021 0.35 ENSDART00000041677
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr2_-_48171112 0.35 ENSDART00000156258
phosphofructokinase, platelet b
chr22_-_26595027 0.35 ENSDART00000184162

chr7_-_58098814 0.34 ENSDART00000147287
ENSDART00000043984
ankyrin 2b, neuronal
chr4_+_7391110 0.34 ENSDART00000160708
ENSDART00000187823
troponin I4a
chr13_-_30645965 0.34 ENSDART00000109307
zinc finger, CCHC domain containing 24
chr10_+_5268054 0.34 ENSDART00000114491
receptor tyrosine kinase-like orphan receptor 2
chr21_-_37733287 0.33 ENSDART00000157826
membrane protein, palmitoylated 1
chr18_-_12327426 0.33 ENSDART00000136992
ENSDART00000114024
family with sequence similarity 107, member B
chr8_+_49433663 0.32 ENSDART00000140481
ENSDART00000180714
NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)
chr20_+_23625387 0.32 ENSDART00000147945
ENSDART00000150497
palladin, cytoskeletal associated protein
chr16_-_5721386 0.32 ENSDART00000136655
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
chr24_-_7321928 0.32 ENSDART00000167570
ENSDART00000045150
ARP3 actin related protein 3 homolog B
chr17_+_24109012 0.32 ENSDART00000156251
EH domain binding protein 1
chr2_-_3419890 0.31 ENSDART00000055618
IBA57, iron-sulfur cluster assembly
chr21_+_723998 0.31 ENSDART00000160956
ornithine decarboxylase antizyme 1b
chr17_-_26926577 0.30 ENSDART00000050202
regulator of calcineurin 3
chr10_+_2899108 0.30 ENSDART00000147031
endoplasmic reticulum aminopeptidase 1a
chr9_-_1702648 0.30 ENSDART00000102934
heterogeneous nuclear ribonucleoprotein A3
chr10_+_35439952 0.30 ENSDART00000006284
HERV-H LTR-associating 2a, tandem duplicate 2
chr3_-_59981476 0.30 ENSDART00000035878
ENSDART00000124038
cerebellar degeneration-related protein 2-like
chr18_+_16125852 0.29 ENSDART00000061106
basic helix-loop-helix family, member e41
chr24_-_28333029 0.29 ENSDART00000149015
ENSDART00000129174
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr8_-_14052349 0.29 ENSDART00000135811
ATPase plasma membrane Ca2+ transporting 3a
chr22_+_14051894 0.28 ENSDART00000142548
aldehyde oxidase 6
chr3_-_59981162 0.28 ENSDART00000128790
cerebellar degeneration-related protein 2-like
chr20_+_40150612 0.28 ENSDART00000143680
ENSDART00000109681
ENSDART00000101041
ENSDART00000121818
triadin
chr22_-_19552796 0.27 ENSDART00000148088
ENSDART00000105485
si:dkey-78l4.14
chr14_-_45967981 0.27 ENSDART00000188062
MACRO domain containing 1
chr16_+_2820340 0.27 ENSDART00000092299
ENSDART00000192931
ENSDART00000148512
si:dkey-288i20.2
chr22_-_11438627 0.27 ENSDART00000007649
MID1 interacting protein 1b
chr6_-_30932078 0.27 ENSDART00000028612
phosphodiesterase 4B, cAMP-specific a
chr20_+_29691118 0.26 ENSDART00000164121
membrane bound O-acyltransferase domain containing 2b
chr17_-_29213710 0.26 ENSDART00000076481
EH-domain containing 4
chr4_+_12292274 0.26 ENSDART00000061070
ENSDART00000150786
makorin, ring finger protein, 1
chr9_-_21230999 0.26 ENSDART00000150160
ENSDART00000102147
phospholipase A1 member A
chr19_-_205104 0.26 ENSDART00000011890
zinc finger and BTB domain containing 22a
chr18_+_2222447 0.26 ENSDART00000185927
PIGB opposite strand 1
chr23_+_33907899 0.26 ENSDART00000159445
citrate synthase
chr4_+_25950372 0.26 ENSDART00000125767
methionyl aminopeptidase 2a
chr11_-_44485700 0.25 ENSDART00000186613
ENSDART00000172828
ENSDART00000113222
mitofusin 1b
chr17_+_21964472 0.25 ENSDART00000063704
ENSDART00000188904
cysteine-rich protein 3
chr4_-_12388535 0.25 ENSDART00000017180
RERG/RAS-like a
chr5_+_39504136 0.25 ENSDART00000121460
PR domain containing 8b
chr1_-_36151377 0.25 ENSDART00000037516
zinc finger protein 827
chr5_+_22970617 0.24 ENSDART00000192859
high mobility group nucleosomal binding domain 7
chr2_-_42558549 0.24 ENSDART00000025997
disco-interacting protein 2 homolog Cb
chr25_+_16601839 0.24 ENSDART00000008986
ATPase H+ transporting V1 subunit E1a
chr18_-_2222128 0.24 ENSDART00000171402
phosphatidylinositol glycan anchor biosynthesis, class B
chr25_+_31277415 0.24 ENSDART00000036275
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr13_+_33282095 0.24 ENSDART00000135200
coiled-coil domain containing 28B
chr4_-_390431 0.24 ENSDART00000067482
ENSDART00000138500
dynein, light chain, Tctex-type 1
chr4_-_15603511 0.23 ENSDART00000122520
ENSDART00000162356
coiled-coil-helix-coiled-coil-helix domain containing 3a
chr1_-_12278056 0.23 ENSDART00000139336
ENSDART00000137463
complexin 2, like
chr11_+_30647545 0.23 ENSDART00000114792
expressed sequence EH507706
chr19_-_22387141 0.23 ENSDART00000151234
epiplakin 1
chr3_-_39305291 0.23 ENSDART00000102674
phospholipase C, delta 3a
chr17_-_30975707 0.22 ENSDART00000138346
Enah/Vasp-like a
chr7_+_55633483 0.22 ENSDART00000180993
ENSDART00000184845
trafficking protein particle complex 2-like
chr9_-_7212973 0.22 ENSDART00000133638
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr21_-_40717678 0.22 ENSDART00000045124
proteasome maturation protein
chr7_-_44704910 0.22 ENSDART00000037850
dynein, cytoplasmic 1, light intermediate chain 2
chr11_-_43200994 0.21 ENSDART00000164700
spectrin, beta, non-erythrocytic 1
chr10_-_24659345 0.21 ENSDART00000128902
ENSDART00000190684
proline and serine rich 1
chr19_-_31686252 0.21 ENSDART00000131721
RHO family interacting cell polarization regulator 2
chr22_+_18389271 0.21 ENSDART00000088270
YjeF N-terminal domain containing 3
chr3_-_5067585 0.21 ENSDART00000169609
thyrotrophic embryonic factor b
chr1_-_51720633 0.20 ENSDART00000045894
ribonuclease H2, subunit A
chr18_+_30567945 0.20 ENSDART00000078894
interferon regulatory factor 8
chr4_-_9579299 0.20 ENSDART00000183079
ENSDART00000192968
ENSDART00000091809
SH3 and multiple ankyrin repeat domains 3b
chr3_+_59851537 0.20 ENSDART00000180997

chr10_-_42751641 0.20 ENSDART00000182734
ENSDART00000113926
zgc:100918
chr11_-_762721 0.20 ENSDART00000166465
synapsin IIb
chr1_+_51496862 0.20 ENSDART00000150433
Meis homeobox 1 a
chr21_+_34119759 0.20 ENSDART00000024750
ENSDART00000128242
high mobility group box 3b
chr12_+_17504559 0.20 ENSDART00000020628
cytohesin 3a
chr18_+_38885309 0.20 ENSDART00000041597
cAMP-regulated phosphoprotein 19a
chr5_-_65662996 0.20 ENSDART00000147707
calmodulin regulated spectrin-associated protein 1b
chr24_-_21989406 0.20 ENSDART00000032963
apolipoprotein O, b
chr19_+_5076617 0.20 ENSDART00000189990
enolase 2
chr16_+_46111849 0.20 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr20_+_29690901 0.19 ENSDART00000142669
membrane bound O-acyltransferase domain containing 2b
chr10_+_23060391 0.19 ENSDART00000079711
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a
chr24_+_39614853 0.19 ENSDART00000165138

chr11_+_13176568 0.19 ENSDART00000125371
ENSDART00000123257
MAP kinase interacting serine/threonine kinase 1
chr8_+_22931427 0.19 ENSDART00000063096
synaptophysin a
chr5_-_32274383 0.19 ENSDART00000122889
myosin, heavy polypeptide 1.3, skeletal muscle
chr1_-_36152131 0.19 ENSDART00000182113
ENSDART00000182904
zinc finger protein 827
chr9_+_54179306 0.19 ENSDART00000189829
thymosin, beta 4 x
chr1_-_53756851 0.19 ENSDART00000122445
v-akt murine thymoma viral oncogene homolog 3b
chr16_+_4531730 0.19 ENSDART00000122861
TCF3 (E2A) fusion partner
chr21_+_34088377 0.18 ENSDART00000170070
myotubularin related protein 1b
chr19_-_5103313 0.18 ENSDART00000037007
triosephosphate isomerase 1a
chr3_-_18410968 0.18 ENSDART00000041842
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10
chr2_+_6243144 0.18 ENSDART00000058258
guanine nucleotide binding protein (G protein), gamma 5
chr19_+_33553586 0.18 ENSDART00000183477
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr25_+_19238175 0.18 ENSDART00000110730
ENSDART00000193619
ENSDART00000154420
diphosphoinositol pentakisphosphate kinase 1b
chr20_-_31497300 0.17 ENSDART00000046841
SAM and SH3 domain containing 1a
chr25_+_6186823 0.17 ENSDART00000153526
ornithine decarboxylase antizyme 2a
chr13_-_44423 0.17 ENSDART00000093247
general transcription factor IIA, 1-like
chr1_-_26063188 0.17 ENSDART00000168640
programmed cell death 4a
chr14_-_17588345 0.17 ENSDART00000143486
selenoprotein T, 2
chr9_-_30165621 0.17 ENSDART00000089543
ABI family, member 3 (NESH) binding protein a
chr1_-_41287914 0.17 ENSDART00000022546
ENSDART00000126853
ENSDART00000125988
regulator of G protein signaling 12b
chr17_-_25649079 0.17 ENSDART00000130955
protein phosphatase 1, catalytic subunit, beta isozyme
chr2_-_37632896 0.17 ENSDART00000008302
insulin receptor a
chr17_-_37395460 0.17 ENSDART00000148160
ENSDART00000075975
cysteine-rich protein 1
chr2_-_9607879 0.17 ENSDART00000056899
thioredoxin domain containing 12 (endoplasmic reticulum)
chr5_-_54481692 0.17 ENSDART00000165719
F-box and WD repeat domain containing 5
chr5_+_24245682 0.17 ENSDART00000049003
ATPase H+ transporting V1 subunit Aa
chr17_-_6451801 0.17 ENSDART00000064700
alpha-L-fucosidase 2
chr9_+_12444494 0.16 ENSDART00000102430
transmembrane protein 41aa
chr8_-_43158486 0.16 ENSDART00000134801
coiled-coil domain containing 92
chr15_-_43327911 0.16 ENSDART00000077386
protease, serine, 16 (thymus)
chr5_+_64732036 0.16 ENSDART00000073950
olfactomedin 1a
chr21_-_3613702 0.16 ENSDART00000139194
dymeclin
chr25_-_23526058 0.16 ENSDART00000191331
ENSDART00000062930
pleckstrin homology-like domain, family A, member 2
chr18_-_15551360 0.16 ENSDART00000159915
ENSDART00000172690
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr25_-_20666328 0.15 ENSDART00000098076
C-terminal Src kinase
chr4_-_1801519 0.15 ENSDART00000188604
ENSDART00000135749
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr7_+_30725473 0.15 ENSDART00000085716
myotubularin related protein 10
chr17_-_30975978 0.15 ENSDART00000051697
Enah/Vasp-like a
chr23_-_26111760 0.15 ENSDART00000164032
regulator of complement activation group 2 gene 1
chr20_-_3087162 0.15 ENSDART00000152495
mitogen-activated protein kinase kinase kinase 5
chr14_-_33297287 0.15 ENSDART00000045555
ENSDART00000138294
ENSDART00000075056
RAB41, member RAS oncogene family
chr16_-_42390441 0.15 ENSDART00000148475
chondroitin sulfate proteoglycan 5a
chr13_+_45431660 0.15 ENSDART00000099950
SYF2 pre-mRNA-splicing factor
chr22_+_28446557 0.15 ENSDART00000089546
ABI family, member 3 (NESH) binding protein b
chr24_+_39186940 0.15 ENSDART00000155817
splA/ryanodine receptor domain and SOCS box containing 3b
chr16_-_44349845 0.15 ENSDART00000170932
regulating synaptic membrane exocytosis 2a
chr21_-_38730557 0.15 ENSDART00000150984
ENSDART00000111885
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr14_-_4044545 0.15 ENSDART00000169527
sorting nexin 25
chr20_+_30578967 0.15 ENSDART00000010494
FGFR1 oncogene partner
chr2_+_5563077 0.14 ENSDART00000111220
Mab-21 domain containing 2
chr4_-_2052687 0.14 ENSDART00000138291
ENSDART00000150844
cleavage and polyadenylation specific factor 6
chr7_+_19738665 0.14 ENSDART00000089333
triokinase/FMN cyclase
chr7_-_66877058 0.14 ENSDART00000155954
adrenomedullin a
chr23_-_33709964 0.14 ENSDART00000143333
ENSDART00000130338
POU class 6 homeobox 1
chr15_+_1134870 0.14 ENSDART00000155392
purinergic receptor P2Y13
chr9_+_34319333 0.14 ENSDART00000035522
ENSDART00000146480
POU class 2 homeobox 1b
chr5_+_51848756 0.14 ENSDART00000087467
ENSDART00000184466
cardiomyopathy associated 5
chr25_+_31227747 0.14 ENSDART00000033872
troponin I type 2a (skeletal, fast), tandem duplicate 1
chr10_+_18911152 0.14 ENSDART00000030205
BCL2 interacting protein 3 like b
chr19_+_1510971 0.14 ENSDART00000157721
solute carrier family 45 member 4
chr12_+_3571770 0.13 ENSDART00000164707
ENSDART00000189819
cytochrome C oxidase assembly factor 3a
chr24_-_24849091 0.13 ENSDART00000133649
ENSDART00000038290
corticotropin releasing hormone b
chr19_-_25772980 0.13 ENSDART00000052393
par-6 family cell polarity regulator gamma b
chr20_-_54198130 0.13 ENSDART00000160409
ADP-ribosylation factor 6a
chr25_-_3058687 0.13 ENSDART00000149117
ENSDART00000137950
si:ch1073-296i8.2
chr12_+_18543783 0.13 ENSDART00000148326
ENSDART00000134530
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr2_+_51645164 0.13 ENSDART00000169600
abhydrolase domain containing 4
chr9_-_54840124 0.13 ENSDART00000137214
ENSDART00000085693
glycoprotein M6Bb
chr8_-_28274251 0.13 ENSDART00000050671
RAP1A, member of RAS oncogene family a
chr9_-_32343673 0.13 ENSDART00000078499
raftlin family member 2
chr14_-_33894915 0.13 ENSDART00000143290
urotensin-related peptide 1
chr2_-_1364678 0.13 ENSDART00000011919
ENSDART00000164674
synovial sarcoma translocation, chromosome 18 (H. sapiens)
chr25_+_5012791 0.13 ENSDART00000156970
si:ch73-265h17.5
chr12_-_19862912 0.13 ENSDART00000145788
shisa family member 9a
chr25_-_25058508 0.13 ENSDART00000087570
ENSDART00000178891

chr21_-_34032650 0.13 ENSDART00000138575
ENSDART00000047515
ring finger protein 145b
chr10_-_27566481 0.12 ENSDART00000078920
autism susceptibility candidate 2a
chr17_-_49438873 0.12 ENSDART00000004424
zinc finger protein 292a
chr24_+_5208171 0.12 ENSDART00000155926
ENSDART00000154464
si:ch73-206p6.1
chr17_-_50490475 0.12 ENSDART00000075159
zgc:113886
chr14_-_30876299 0.12 ENSDART00000180305
ubiquitin-like 3b
chr3_-_58798815 0.12 ENSDART00000082920
si:ch73-281f12.4
chr16_+_4695075 0.12 ENSDART00000039054
mitochondrial trans-2-enoyl-CoA reductase

Network of associatons between targets according to the STRING database.

First level regulatory network of pou2f3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 0.9 GO:0032623 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 1.0 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.4 GO:0060043 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.1 0.5 GO:0090199 regulation of mitochondrial membrane potential(GO:0051881) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.7 GO:0046323 glucose import(GO:0046323)
0.1 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.4 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.2 GO:2000405 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.1 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.2 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.1 0.4 GO:0019563 glycerol catabolic process(GO:0019563)
0.1 0.3 GO:0070084 protein initiator methionine removal(GO:0070084)
0.1 0.2 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.2 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.1 0.5 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.4 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.2 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.0 0.1 GO:1990120 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833) messenger ribonucleoprotein complex assembly(GO:1990120)
0.0 0.1 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.1 GO:0051580 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.0 0.2 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.2 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.1 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.0 0.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.0 0.2 GO:0045109 intermediate filament organization(GO:0045109) intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0051228 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.0 0.2 GO:1901910 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.0 0.2 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.3 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.0 0.1 GO:0019677 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.3 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0045822 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.0 0.3 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.4 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.2 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.0 0.3 GO:0030431 sleep(GO:0030431)
0.0 0.2 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.0 0.1 GO:0002164 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.0 0.2 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.5 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.1 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.0 0.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.0 GO:0051204 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.0 0.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.4 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.8 GO:0050879 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0014823 response to activity(GO:0014823)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.0 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0 0.1 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.1 GO:0048669 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.0 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.2 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.2 GO:0000186 activation of MAPKK activity(GO:0000186)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008091 spectrin(GO:0008091)
0.1 0.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 1.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.9 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:1990879 CST complex(GO:1990879)
0.0 0.1 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.8 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.4 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.3 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0043195 terminal bouton(GO:0043195)
0.0 1.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0005521 lamin binding(GO:0005521)
0.2 0.5 GO:0052833 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.9 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.3 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1 1.0 GO:0008199 ferric iron binding(GO:0008199)
0.1 1.3 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.2 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 1.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.2 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.8 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.7 GO:0005355 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.0 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0043560 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.0 0.3 GO:0070095 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.3 GO:0016208 AMP binding(GO:0016208)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.0 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor