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PRJNA207719: Tissue specific transcriptome profiling
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Results for pou2f1b
Z-value: 1.79
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Transcription factors associated with pou2f1b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| pou2f1b | dr11_v1_chr9_+_34319333_34319333 | -0.81 | 9.3e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_+_35458190 Show fit | 1.61 |
ENSDART00000051313
|
fructose-1,6-bisphosphatase 1b |
|
| chr1_+_52735484 Show fit | 1.60 |
ENSDART00000182076
|
|
|
| chr24_+_23959487 Show fit | 1.28 |
ENSDART00000080487
|
homogentisate 1,2-dioxygenase |
|
| chr19_+_2835240 Show fit | 1.22 |
ENSDART00000190838
|
CUB domain containing protein 1 |
|
| chr4_-_8043839 Show fit | 1.20 |
ENSDART00000190047
ENSDART00000057567 |
si:ch211-240l19.5 |
|
| chr25_-_18454016 Show fit | 1.20 |
ENSDART00000005877
|
carboxypeptidase A1 (pancreatic) |
|
| chr20_+_10538025 Show fit | 1.19 |
ENSDART00000129762
|
serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like |
|
| chr10_+_2669405 Show fit | 1.15 |
ENSDART00000110202
|
chemokine (C-C motif) ligand 27b |
|
| chr24_-_23758003 Show fit | 1.14 |
ENSDART00000178085
|
Danio rerio minichromosome maintenance domain containing 2 (mcmdc2), mRNA. |
|
| chr1_-_56080112 Show fit | 1.04 |
ENSDART00000075469
ENSDART00000161473 |
complement component c3a, duplicate 6 |
Network of associatons between targets according to the STRING database.
First level regulatory network of pou2f1b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | GO:0010951 | negative regulation of endopeptidase activity(GO:0010951) |
| 0.0 | 1.8 | GO:0072376 | complement activation(GO:0006956) protein activation cascade(GO:0072376) |
| 0.5 | 1.6 | GO:0005986 | sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351) |
| 0.1 | 1.6 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.1 | 1.3 | GO:1902222 | L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222) |
| 0.0 | 1.1 | GO:0007131 | reciprocal meiotic recombination(GO:0007131) |
| 0.0 | 1.1 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
| 0.1 | 1.0 | GO:0030216 | keratinocyte differentiation(GO:0030216) |
| 0.1 | 0.9 | GO:0030311 | poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
| 0.0 | 0.9 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0019814 | immunoglobulin complex(GO:0019814) |
| 0.0 | 1.1 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.9 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.2 | 0.7 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 0.7 | GO:0044853 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
| 0.1 | 0.6 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 0.6 | GO:0098844 | postsynaptic endocytic zone membrane(GO:0098844) |
| 0.0 | 0.6 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 0.5 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 0.5 | GO:0030428 | cell septum(GO:0030428) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.5 | GO:0004866 | endopeptidase inhibitor activity(GO:0004866) |
| 0.0 | 2.2 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.5 | 1.6 | GO:0042132 | fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132) |
| 0.1 | 1.6 | GO:0004875 | complement receptor activity(GO:0004875) |
| 0.0 | 1.3 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 1.2 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 1.2 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) |
| 0.0 | 1.1 | GO:0019956 | chemokine binding(GO:0019956) |
| 0.0 | 1.1 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 1.1 | GO:0003724 | RNA helicase activity(GO:0003724) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.0 | 1.2 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 1.2 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 1.1 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 1.0 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.6 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.0 | 0.6 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.0 | 0.4 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 0.4 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.3 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 1.3 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.1 | 1.2 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 1.1 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.0 | 1.0 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.0 | 1.0 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 0.8 | REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.0 | 0.8 | REACTOME PRE NOTCH EXPRESSION AND PROCESSING | Genes involved in Pre-NOTCH Expression and Processing |
| 0.1 | 0.7 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 0.7 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |