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PRJNA207719: Tissue specific transcriptome profiling
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Results for pgr
Z-value: 1.52
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Transcription factors associated with pgr
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| pgr | dr11_v1_chr18_+_41820039_41820039 | 0.15 | 8.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr21_+_10866421 Show fit | 1.14 |
ENSDART00000137858
|
alpha-kinase 2 |
|
| chr9_-_22831836 Show fit | 1.06 |
ENSDART00000142585
|
nebulin |
|
| chr6_+_41096058 Show fit | 0.79 |
ENSDART00000028373
|
FK506 binding protein 5 |
|
| chr21_+_20901505 Show fit | 0.76 |
ENSDART00000132741
|
complement component 7b |
|
| chr1_+_7538909 Show fit | 0.75 |
ENSDART00000148276
|
myosin, light polypeptide 3, skeletal muscle |
|
| chr5_-_32308526 Show fit | 0.74 |
ENSDART00000193758
|
myosin, heavy polypeptide 1.1, skeletal muscle |
|
| chr7_+_39389273 Show fit | 0.72 |
ENSDART00000191298
|
troponin I type 2b (skeletal, fast), tandem duplicate 2 |
|
| chr22_-_278328 Show fit | 0.70 |
ENSDART00000098072
|
myosin, heavy polypeptide 1.1, skeletal muscle |
|
| chr4_-_14328997 Show fit | 0.68 |
ENSDART00000091151
|
neural EGFL like 2b |
|
| chr16_+_47308856 Show fit | 0.67 |
ENSDART00000170103
|
collagen, type XXVIII, alpha 1b |
Network of associatons between targets according to the STRING database.
First level regulatory network of pgr
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.7 | GO:0001757 | somite specification(GO:0001757) segment specification(GO:0007379) |
| 0.0 | 1.2 | GO:1903670 | regulation of sprouting angiogenesis(GO:1903670) |
| 0.2 | 1.1 | GO:0071691 | cardiac muscle thin filament assembly(GO:0071691) |
| 0.0 | 1.1 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 1.1 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
| 0.0 | 1.0 | GO:0006956 | complement activation(GO:0006956) |
| 0.0 | 0.8 | GO:0019835 | cytolysis(GO:0019835) |
| 0.0 | 0.6 | GO:0048936 | peripheral nervous system neuron axonogenesis(GO:0048936) |
| 0.1 | 0.5 | GO:0098700 | neurotransmitter loading into synaptic vesicle(GO:0098700) |
| 0.0 | 0.5 | GO:0042761 | very long-chain fatty acid biosynthetic process(GO:0042761) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.7 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 1.5 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 1.1 | GO:0005861 | troponin complex(GO:0005861) |
| 0.0 | 0.8 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.0 | 0.5 | GO:0098563 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.1 | 0.4 | GO:0005592 | collagen type XI trimer(GO:0005592) |
| 0.0 | 0.4 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.0 | 0.3 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.0 | 0.3 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 0.3 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.3 | 1.2 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 0.7 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 0.6 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
| 0.0 | 0.5 | GO:0005326 | neurotransmitter transporter activity(GO:0005326) |
| 0.1 | 0.4 | GO:0015432 | canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432) |
| 0.0 | 0.4 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.0 | 0.4 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.0 | 0.4 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
| 0.1 | 0.3 | GO:0008746 | NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 0.4 | ST ADRENERGIC | Adrenergic Pathway |
| 0.0 | 0.4 | NABA COLLAGENS | Genes encoding collagen proteins |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.4 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.4 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.1 | 0.3 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.0 | 0.3 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 0.2 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.0 | 0.1 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 0.1 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.0 | 0.1 | REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors |