ISMARA results: patz1

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PRJNA207719: Tissue specific transcriptome profiling

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Results for patz1

Z-value: 2.17

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Transcription factors associated with patz1

Gene Symbol	Gene ID	Gene Info
patz1 NCBI UniProt	ENSDARG00000076584	POZ/BTB and AT hook containing zinc finger 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
patz1	dr11_v1_chr6_+_40951227_40951227	0.71	1.7e-01	Click!

Activity profile of patz1 motif

Sorted Z-values of patz1 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr19_-_5254699 Show fit	2.77	ENSDART00000081951	stx1b NCBI UniProt Show fit	syntaxin 1B
chr2_+_58221163 Show fit	2.70	ENSDART00000157939	FO704813.1 NCBI UniProt Show fit
chr1_-_14233815 Show fit	2.15	ENSDART00000044896	camk2d2 NCBI UniProt Show fit	calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr25_-_13363286 Show fit	2.10	ENSDART00000163735 ENSDART00000169119	ndrg4 NCBI UniProt Show fit	NDRG family member 4
chr2_-_44282796 Show fit	1.99	ENSDART00000163040 ENSDART00000166923 ENSDART00000056372 ENSDART00000109251 ENSDART00000132682	mpz NCBI UniProt Show fit	myelin protein zero
chr2_+_59015878 Show fit	1.85	ENSDART00000148816 ENSDART00000122795	si:ch1073-391i24.1 NCBI UniProt Show fit	si:ch1073-391i24.1
chr7_+_73630751 Show fit	1.82	ENSDART00000159745	PCP4L1 NCBI UniProt Show fit	si:dkey-46i9.1
chr11_+_25112269 Show fit	1.81	ENSDART00000147546	ndrg3a NCBI UniProt Show fit	ndrg family member 3a
chr5_+_36614196 Show fit	1.79	ENSDART00000150574	nova1 NCBI UniProt Show fit	neuro-oncological ventral antigen 1
chr16_-_42390441 Show fit	1.77	ENSDART00000148475	cspg5a NCBI UniProt Show fit	chondroitin sulfate proteoglycan 5a

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of patz1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.4	GO:0099550	trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.0	2.9	GO:0006813	potassium ion transport(GO:0006813)
0.6	2.8	GO:0098967	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0	2.5	GO:0070588	calcium ion transmembrane transport(GO:0070588)
0.1	2.4	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2	2.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.1	1.8	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	1.8	GO:0006909	phagocytosis(GO:0006909)
0.2	1.7	GO:0098935	dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.1	1.6	GO:0048923	posterior lateral line neuromast hair cell differentiation(GO:0048923)

Showing 1 to 10 of 145 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.5	GO:0060076	excitatory synapse(GO:0060076)
0.2	2.9	GO:0044295	axonal growth cone(GO:0044295)
0.1	2.8	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.2	2.6	GO:0031680	G-protein beta/gamma-subunit complex(GO:0031680)
0.4	2.5	GO:0070062	extracellular exosome(GO:0070062)
0.2	2.4	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0	1.8	GO:0043025	neuronal cell body(GO:0043025)
0.0	1.7	GO:0032587	ruffle membrane(GO:0032587)
0.0	1.7	GO:0005871	kinesin complex(GO:0005871)
0.1	1.6	GO:0043256	basal lamina(GO:0005605) laminin complex(GO:0043256)

Showing 1 to 10 of 50 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.6	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.1	3.3	GO:0017075	syntaxin-1 binding(GO:0017075)
0.1	2.8	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	2.8	GO:0030295	kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0	2.7	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	2.6	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.1	2.6	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	2.2	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	2.2	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.1	1.7	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)

Showing 1 to 10 of 87 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.7	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	0.9	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.9	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	0.8	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.8	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.7	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.6	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.5	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.5	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway

Showing 1 to 10 of 16 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.8	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2	2.6	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	1.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	1.4	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	1.4	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.2	1.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.1	1.0	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	1.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.8	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction

Showing 1 to 10 of 25 entries

Results for patz1

Z-value: 2.17

Motif logo

Transcription factors associated with patz1

Activity-expression correlation:

Activity profile of patz1 motif

Sorted Z-values of patz1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of patz1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: