PRJNA207719: Tissue specific transcriptome profiling


Results for onecut3a+onecut3b

Z-value: 1.48

Motif logo

Transcription factors associated with onecut3a+onecut3b

Gene Symbol Gene ID Gene Info
ENSDARG00000056395 one cut homeobox 3a
ENSDARG00000091059 one cut homeobox 3b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot

Activity profile of onecut3a+onecut3b motif

Sorted Z-values of onecut3a+onecut3b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_5291256 2.02 ENSDART00000150864
chr1_-_21409877 1.81 ENSDART00000102782
glutamate receptor, ionotropic, AMPA 2a
chr14_+_35748385 1.72 ENSDART00000064617
glutamate receptor, ionotropic, AMPA 2b
chr14_+_35748206 1.69 ENSDART00000177391
glutamate receptor, ionotropic, AMPA 2b
chr3_-_28665291 1.64 ENSDART00000151670
F-box and leucine-rich repeat protein 16
chr6_+_3828560 1.61 ENSDART00000185273
glutamate decarboxylase 1b
chr8_-_14052349 1.58 ENSDART00000135811
ATPase plasma membrane Ca2+ transporting 3a
chr19_+_25649626 1.53 ENSDART00000146947
tachykinin 1
chr2_+_47581997 1.41 ENSDART00000112579
secretogranin II (chromogranin C), b
chr2_+_47582488 1.33 ENSDART00000149967
secretogranin II (chromogranin C), b
chr18_+_642889 1.29 ENSDART00000189007

chr23_-_15216654 1.26 ENSDART00000131649
sulfatase 2b
chr16_-_12173399 1.25 ENSDART00000142574
calsyntenin 3
chr16_-_12173554 1.22 ENSDART00000110567
calsyntenin 3
chr11_+_25064519 1.21 ENSDART00000016181
ndrg family member 3a
chr10_-_31782616 1.14 ENSDART00000128839
fasciculation and elongation protein zeta 1 (zygin I)
chr1_-_23157583 1.12 ENSDART00000144208
adhesion G protein-coupled receptor L3.1
chr9_+_32358514 1.09 ENSDART00000144608
phospholipase C like 1
chr11_-_10798021 1.07 ENSDART00000167112
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr19_-_17526735 1.07 ENSDART00000189391
thyroid hormone receptor beta
chr24_-_23320223 1.06 ENSDART00000135846
zinc finger homeobox 4
chr5_-_71460556 1.06 ENSDART00000108804
bone morphogenetic protein/retinoic acid inducible neural-specific 1
chr22_+_17359346 1.05 ENSDART00000145434
G protein-coupled receptor 52
chr12_+_9342502 1.04 ENSDART00000152808
potassium voltage-gated channel, subfamily H (eag-related), member 6b
chr2_+_25860344 1.01 ENSDART00000178841
solute carrier family 7, member 14a
chr11_+_6819050 1.00 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr13_+_36144341 0.99 ENSDART00000182930
chr3_-_28120092 0.98 ENSDART00000151143
RNA binding fox-1 homolog 1
chr5_+_19309877 0.98 ENSDART00000190338
RUN and SH3 domain containing 2
chr14_+_21783229 0.96 ENSDART00000170784
ankyrin repeat domain 13 family, member D
chr21_-_17482465 0.94 ENSDART00000004548
BarH-like homeobox 1b
chr23_-_28025943 0.92 ENSDART00000181146
Sp5 transcription factor-like
chr14_-_31893996 0.92 ENSDART00000173222
G protein-coupled receptor 101
chr3_+_32443395 0.91 ENSDART00000188447
proline rich 12b
chr1_+_16144615 0.91 ENSDART00000054707
tumor suppressor candidate 3
chr21_-_23475361 0.90 ENSDART00000156658
neural cell adhesion molecule 1a
chr25_-_9805269 0.90 ENSDART00000192048
leucine rich repeat containing 4C
chr25_-_11088839 0.87 ENSDART00000154748
synaptic vesicle glycoprotein 2Bb
chr2_+_5887626 0.80 ENSDART00000147831
chr8_-_23081511 0.79 ENSDART00000142015
chr3_+_39853788 0.79 ENSDART00000154869
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr7_+_63325819 0.75 ENSDART00000085612
protocadherin 7b
chr7_+_73649686 0.74 ENSDART00000185589
chr19_-_874888 0.73 ENSDART00000007206
eomesodermin homolog a
chr2_-_56387041 0.73 ENSDART00000036240
ceramide synthase 4b
chr3_-_60142530 0.70 ENSDART00000153247
chr17_+_23937262 0.67 ENSDART00000113276
chr17_-_20897250 0.65 ENSDART00000088106
ankyrin 3b
chr3_+_1492174 0.64 ENSDART00000112979
SRY (sex determining region Y)-box 10
chr15_+_17446796 0.63 ENSDART00000157189
sorting nexin 19b
chr1_-_36151377 0.63 ENSDART00000037516
zinc finger protein 827
chr8_+_9866351 0.62 ENSDART00000133985
potassium voltage-gated channel, Shal-related subfamily, member 1
chr6_-_17999776 0.62 ENSDART00000183048
regulatory associated protein of MTOR, complex 1
chr17_-_45247332 0.62 ENSDART00000016815
tau tubulin kinase 2a
chr15_+_17441734 0.58 ENSDART00000153729
sorting nexin 19b
chr16_-_26255877 0.58 ENSDART00000146214
Ets2 repressor factor like 1
chr12_+_10116912 0.58 ENSDART00000189630
chr2_+_21309272 0.58 ENSDART00000141322
zinc finger and BTB domain containing 47a
chr10_-_15405564 0.56 ENSDART00000020665
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr16_+_21738194 0.56 ENSDART00000163688
Danio rerio si:ch211-154o6.4 (si:ch211-154o6.4), mRNA.
chr2_-_39759059 0.55 ENSDART00000007333
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36a
chr2_+_45300512 0.55 ENSDART00000144704
calmodulin regulated spectrin-associated protein family, member 2b
chr12_+_32729470 0.53 ENSDART00000175712
RNA binding fox-1 homolog 3a
chr22_-_3564563 0.53 ENSDART00000145114
protein tyrosine phosphatase, receptor type, s, a
chr16_-_26435431 0.52 ENSDART00000187526
multiple EGF-like-domains 8
chr19_+_19512515 0.51 ENSDART00000180065
JAZF zinc finger 1a
chr2_-_32505091 0.51 ENSDART00000141884
Fas apoptotic inhibitory molecule 2a
chr2_+_42871831 0.50 ENSDART00000171393
EFR3 homolog A (S. cerevisiae)
chr5_-_57652168 0.50 ENSDART00000166245
expressed sequence EH456644
chr21_-_43482426 0.48 ENSDART00000192901
ankyrin repeat domain 46a
chr19_-_18855717 0.48 ENSDART00000158192
palmitoyl-protein thioesterase 2
chr19_-_18855513 0.47 ENSDART00000162708
palmitoyl-protein thioesterase 2
chr4_+_7827261 0.47 ENSDART00000129568
phytanoyl-CoA 2-hydroxylase
chr2_-_17044959 0.46 ENSDART00000090260
chloride channel, voltage-sensitive 2a
chr10_-_11840353 0.46 ENSDART00000127581
tripartite motif containing 23
chr14_-_4044545 0.44 ENSDART00000169527
sorting nexin 25
chr13_-_37383625 0.44 ENSDART00000192888
potassium voltage-gated channel, subfamily H (eag-related), member 5b
chr15_+_19458982 0.43 ENSDART00000132665
chr11_-_22605981 0.43 ENSDART00000186923
chr7_-_49651378 0.42 ENSDART00000015040
-Ha-ras Harvey rat sarcoma viral oncogene homolog b
chr18_+_3579829 0.42 ENSDART00000158763
leucine-rich repeats and calponin homology (CH) domain containing 3
chr7_+_40658003 0.41 ENSDART00000172435
limb development membrane protein 1
chr15_-_34418525 0.40 ENSDART00000147582
alkylglycerol monooxygenase
chr23_+_12454542 0.40 ENSDART00000182259
chr5_+_50788329 0.39 ENSDART00000050979
family with sequence similarity 81, member B
chr14_+_36628131 0.39 ENSDART00000188625
chr18_-_20560007 0.38 ENSDART00000141367
chr14_+_11946395 0.38 ENSDART00000193290
FERM and PDZ domain containing 3
chr17_-_8169774 0.37 ENSDART00000091828
spectrin repeat containing, nuclear envelope 1b
chr20_-_3403033 0.37 ENSDART00000092264
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr3_-_8399774 0.36 ENSDART00000190238
RNA binding fox-1 homolog 3b
chr25_-_13789955 0.35 ENSDART00000167742
cytoskeleton associated protein 5
chr18_-_44611252 0.34 ENSDART00000173095
sprouty-related, EVH1 domain containing 3
chr4_-_4261673 0.34 ENSDART00000150694
CD9 molecule b
chr15_-_33325019 0.33 ENSDART00000181092
neurobeachin b
chr6_-_40352215 0.33 ENSDART00000103992
tubulin tyrosine ligase-like family, member 3
chr22_-_38360205 0.32 ENSDART00000162055
MAP/microtubule affinity-regulating kinase 1
chr1_+_47391404 0.32 ENSDART00000113559
B cell CLL/lymphoma 9
chr9_+_38503233 0.32 ENSDART00000140331
leishmanolysin-like (metallopeptidase M8 family)
chr17_-_26507289 0.31 ENSDART00000155616
coiled-coil serine-rich protein 2a
chr23_-_20002459 0.31 ENSDART00000163396
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr6_-_33707278 0.31 ENSDART00000188103
microtubule associated serine/threonine kinase 2
chr3_-_48612078 0.30 ENSDART00000169923
nudE neurodevelopment protein 1-like 1b
chr1_+_51391082 0.29 ENSDART00000063936
autophagy related 4D, cysteine peptidase a
chr20_-_30931139 0.26 ENSDART00000006778
acetyl-CoA acetyltransferase 2
chr6_-_58764672 0.25 ENSDART00000154322
sterol O-acyltransferase 2
chr11_+_25259058 0.25 ENSDART00000154109
tumor protein p53 inducible nuclear protein 2
chr19_+_42886413 0.25 ENSDART00000151298
cAMP-regulated phosphoprotein, 21
chr21_+_3901775 0.25 ENSDART00000053609
dolichyldiphosphatase 1
chr7_-_56831621 0.25 ENSDART00000182912
SUMO/sentrin peptidase family member, NEDD8 specific
chr21_-_39058490 0.25 ENSDART00000114885
aldehyde dehydrogenase 3 family, member A2b
chr10_-_28835771 0.24 ENSDART00000192220
activated leukocyte cell adhesion molecule a
chr11_+_5817202 0.24 ENSDART00000126084
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 3
chr12_-_47793857 0.23 ENSDART00000161294
DPY30 domain containing 2
chr9_+_19421841 0.21 ENSDART00000159090
phosphodiesterase 9A
chr12_-_35582683 0.21 ENSDART00000167933
SEC24 homolog C, COPII coat complex component
chr2_+_22042745 0.21 ENSDART00000132039
thymocyte selection-associated high mobility group box
chr5_-_14211487 0.20 ENSDART00000135731
neuropeptide FF receptor 1 like 2
chr20_-_23171430 0.20 ENSDART00000109234
spermatogenesis associated 18
chr20_+_22130284 0.19 ENSDART00000025575
clock circadian regulator a
chr17_-_20897407 0.19 ENSDART00000149481
ankyrin 3b
chr16_+_35728992 0.18 ENSDART00000158442
MAP7 domain containing 1a
chr3_-_44753325 0.17 ENSDART00000074543
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr18_+_15876385 0.17 ENSDART00000142527
early endosome antigen 1
chr19_-_48039400 0.17 ENSDART00000166748
colony stimulating factor 3 (granulocyte) b
chr20_+_16639848 0.16 ENSDART00000063944
transmembrane protein 30Ab
chr21_-_28901095 0.16 ENSDART00000180820
CXXC finger protein 5a
chr12_+_47794089 0.16 ENSDART00000160726
polymerase (RNA) III (DNA directed) polypeptide A
chr16_+_22587661 0.16 ENSDART00000129612
Src homology 2 domain containing E
chr9_-_20853439 0.16 ENSDART00000028247
ganglioside induced differentiation associated protein 2
chr14_-_41243180 0.16 ENSDART00000184548
dystrophin related protein 2
chr12_+_48204891 0.15 ENSDART00000190534
nodal-related 2
chr14_+_49376011 0.15 ENSDART00000020961
TNFAIP3 interacting protein 1
chr19_+_11984725 0.15 ENSDART00000185960
sperm associated antigen 1a
chr22_+_25554232 0.15 ENSDART00000131218
alanyl-tRNA synthetase 2, mitochondrial (putative)
chr20_+_42978499 0.15 ENSDART00000138793
chr17_-_14451405 0.15 ENSDART00000146786
jnk1/mapk8 associated membrane protein
chr16_+_23960744 0.14 ENSDART00000058965
apolipoprotein Eb
chr19_-_21766461 0.14 ENSDART00000104279
zinc finger protein 516
chr6_-_16456093 0.13 ENSDART00000083305
solute carrier family 19 (thiamine transporter), member 2
chr2_+_44781185 0.13 ENSDART00000187103
endothelin converting enzyme 2a
chr25_-_37071036 0.13 ENSDART00000150178
WW domain containing oxidoreductase
chr18_-_44847855 0.13 ENSDART00000086823
signal recognition particle receptor (docking protein)
chr21_-_40799404 0.12 ENSDART00000147405
chr2_-_39086540 0.12 ENSDART00000110826
chr15_-_7598542 0.12 ENSDART00000173092
glucan (1,4-alpha-), branching enzyme 1b
chr11_+_24815667 0.12 ENSDART00000141730
RAB interacting factor
chr15_+_21947117 0.11 ENSDART00000156234
tetratricopeptide repeat domain 12
chr7_-_41693004 0.11 ENSDART00000121509
MAM and LDL receptor class A domain containing 1
chr18_-_17075098 0.11 ENSDART00000042496
transport and golgi organization 6 homolog (Drosophila)
chr13_-_31166544 0.10 ENSDART00000146250
mitogen-activated protein kinase 8a
chr7_-_73854476 0.10 ENSDART00000186481
chr24_-_15131831 0.10 ENSDART00000028410
CD226 molecule
chr21_-_22812417 0.10 ENSDART00000079151
transient receptor potential cation channel, subfamily C, member 6a
chr12_+_26512569 0.09 ENSDART00000066264
chr9_+_27329640 0.09 ENSDART00000111039
chr4_-_76488854 0.08 ENSDART00000132323
finTRIM family, member 51
chr8_-_621142 0.08 ENSDART00000187576
chr7_+_33372680 0.08 ENSDART00000193436
glucuronic acid epimerase b
chr2_-_6262441 0.08 ENSDART00000092190
ADP-ribosylation factor-like 14
chr12_-_18883079 0.06 ENSDART00000178619
shisa family member 8b
chr25_+_22017182 0.06 ENSDART00000156517
chr16_-_54942532 0.06 ENSDART00000078887
transmembrane protein 222a
chr21_+_4116437 0.06 ENSDART00000167791
Rap guanine nucleotide exchange factor (GEF) 1b
chr19_+_43256986 0.06 ENSDART00000182336
diacylglycerol kinase delta
chr3_-_30434016 0.05 ENSDART00000150958
leucine rich repeat containing 4Ba
chr25_-_13703826 0.05 ENSDART00000163398
phospholipase A2, group XV
chr10_+_7593185 0.04 ENSDART00000162617
protein phosphatase 2, catalytic subunit, beta isozyme
chr2_+_13462305 0.03 ENSDART00000149309
cilia and flagella associated protein 57
chr2_-_42958619 0.03 ENSDART00000144317
otoconin 90
chr16_-_31525290 0.03 ENSDART00000109996
WNT1 inducible signaling pathway protein 1b
chr24_-_25030173 0.02 ENSDART00000126395
nucleoporin 58
chr7_+_30933867 0.02 ENSDART00000156325
tight junction protein 1a
chr4_+_25691642 0.02 ENSDART00000139053
acyl-CoA thioesterase 18
chr8_+_27807266 0.01 ENSDART00000170037
capping protein (actin filament) muscle Z-line, alpha 1b
chr5_+_18014931 0.01 ENSDART00000142562
activating signal cointegrator 1 complex subunit 2
chr8_-_14484599 0.01 ENSDART00000057644
LIM homeobox 4
chr15_-_7598294 0.01 ENSDART00000165898
glucan (1,4-alpha-), branching enzyme 1b
chr3_+_39958407 0.01 ENSDART00000099754
coiled-coil domain containing 97
chr23_+_25993686 0.00 ENSDART00000053993
WNT1 inducible signaling pathway protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of onecut3a+onecut3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 0.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 1.0 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.3 1.5 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 0.9 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.3 2.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.3 1.1 GO:0046551 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.2 0.7 GO:0060571 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.2 0.6 GO:1903644 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.2 0.5 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 1.1 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.1 1.8 GO:0048899 anterior lateral line development(GO:0048899)
0.1 1.1 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 1.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 1.2 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.5 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 2.7 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.1 0.3 GO:0032615 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.1 0.3 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.9 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.1 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.0 0.8 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.5 GO:0031111 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.0 0.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.3 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.1 GO:0002347 response to tumor cell(GO:0002347) natural killer cell cytokine production(GO:0002370) immune response to tumor cell(GO:0002418) natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell cytokine production(GO:0002727) positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860) positive regulation of mast cell activation(GO:0033005) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.9 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.3 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.3 GO:0034434 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 0.2 GO:0001709 cell fate determination(GO:0001709)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.9 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 1.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 1.0 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.8 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.6 GO:0038202 TORC1 signaling(GO:0038202) cellular response to amino acid stimulus(GO:0071230)
0.0 0.3 GO:0048885 neuromast deposition(GO:0048885)
0.0 0.3 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.4 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 1.0 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.5 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0045117 azole transport(GO:0045117)
0.0 0.7 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0072380 TRC complex(GO:0072380)
0.1 5.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.4 GO:0005880 nuclear microtubule(GO:0005880)
0.1 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.5 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.8 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 2.7 GO:0030141 secretory granule(GO:0030141)
0.0 0.4 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.6 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.6 GO:0005795 Golgi stack(GO:0005795)
0.0 0.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.6 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.1 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.3 GO:1990752 microtubule plus-end(GO:0035371) microtubule end(GO:1990752)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 3.3 GO:0030424 axon(GO:0030424)
0.0 1.5 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.5 1.5 GO:0031835 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.3 5.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.3 1.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 0.5 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.3 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.1 0.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 1.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.3 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 1.1 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.1 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 1.5 GO:0005249 voltage-gated potassium channel activity(GO:0005249)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.4 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation