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PRJNA207719: Tissue specific transcriptome profiling

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Results for nkx2.4a+nkx2.4b

Z-value: 0.26

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Transcription factors associated with nkx2.4a+nkx2.4b

Gene Symbol Gene ID Gene Info
ENSDARG00000075107 NK2 homeobox 4a
ENSDARG00000104107 NK2 homeobox 4b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx2.4bdr11_v1_chr20_+_48803248_488032480.059.4e-01Click!
nkx2.4adr11_v1_chr17_-_42097267_420972670.039.6e-01Click!

Activity profile of nkx2.4a+nkx2.4b motif

Sorted Z-values of nkx2.4a+nkx2.4b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_35708450 0.08 ENSDART00000193886
iroquois homeobox 5a
chr2_-_38284648 0.07 ENSDART00000148281
ENSDART00000132621
si:ch211-14a17.7
chr2_-_26499842 0.07 ENSDART00000186929

chr14_+_21106444 0.06 ENSDART00000075744
ENSDART00000132363
aldolase b, fructose-bisphosphate
chr16_-_31675669 0.05 ENSDART00000168848
ENSDART00000158331
complement component 1, r subcomponent
chr22_-_36856405 0.05 ENSDART00000029588
kininogen 1
chr18_+_50669456 0.05 ENSDART00000163005
si:dkey-151j17.4
chr2_-_898899 0.05 ENSDART00000058289
dual specificity phosphatase 22b
chr19_+_7938121 0.04 ENSDART00000140053
ENSDART00000146649
si:dkey-266f7.5
chr1_-_7603734 0.04 ENSDART00000009315
myxovirus (influenza) resistance B
chr6_-_13114821 0.04 ENSDART00000164579
ENSDART00000165375
zgc:194469
chr15_+_34963316 0.04 ENSDART00000153840
si:ch73-95l15.5
chr24_+_19210001 0.04 ENSDART00000179373
ENSDART00000139299
zgc:162928
chr4_-_43731342 0.04 ENSDART00000146627
si:ch211-226o13.3
chr10_-_15048781 0.04 ENSDART00000038401
ENSDART00000155674
si:ch211-95j8.2
chr8_-_51293265 0.04 ENSDART00000127875
ENSDART00000181145
bone morphogenetic protein 1a
chr15_-_26552652 0.04 ENSDART00000152336
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr24_+_33392698 0.04 ENSDART00000122579
si:ch73-173p19.1
chr21_-_41147818 0.04 ENSDART00000167339
ENSDART00000192730
muscle segment homeobox 2b
chr4_+_50410452 0.04 ENSDART00000146006
si:dkey-156k2.8
chr8_-_39884359 0.04 ENSDART00000131372
malectin
chr12_+_49100365 0.04 ENSDART00000171905

chr7_+_29163762 0.03 ENSDART00000173762
solute carrier family 38, member 8b
chr10_+_5268054 0.03 ENSDART00000114491
receptor tyrosine kinase-like orphan receptor 2
chr4_+_1146346 0.03 ENSDART00000166467
cholinergic receptor, muscarinic 2a
chr7_+_13830052 0.03 ENSDART00000191360
abhydrolase domain containing 2a
chr15_-_26552393 0.03 ENSDART00000150152
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2b
chr23_+_4324625 0.03 ENSDART00000146302
ENSDART00000136792
ENSDART00000135027
ENSDART00000179819
serum/glucocorticoid regulated kinase 2a
chr22_-_21897203 0.03 ENSDART00000158501
ENSDART00000105566
ENSDART00000136795
guanine nucleotide binding protein (G protein), alpha 11a (Gq class)
chr18_+_23397010 0.03 ENSDART00000193765
multiple C2 domains, transmembrane 2a
chr12_+_5977777 0.03 ENSDART00000152302
si:ch211-131k2.2
chr10_-_32524035 0.03 ENSDART00000137608
diacylglycerol O-acyltransferase 2
chr13_-_51846224 0.03 ENSDART00000184663

chr10_+_2742499 0.03 ENSDART00000122847
G protein-coupled receptor kinase 5
chr2_+_36608387 0.03 ENSDART00000159541
p21 protein (Cdc42/Rac)-activated kinase 2a
chr1_-_59232267 0.03 ENSDART00000169658
ENSDART00000163257
A kinase (PRKA) anchor protein 8-like
chr8_-_30316436 0.03 ENSDART00000111358
ENSDART00000167065
zgc:162939
chr14_+_23709543 0.03 ENSDART00000136909
glucosamine-6-phosphate deaminase 1
chr17_-_28097760 0.03 ENSDART00000149861
lysine (K)-specific demethylase 1a
chr15_-_28904371 0.03 ENSDART00000155154
echinoderm microtubule associated protein like 2
chr19_-_35400819 0.03 ENSDART00000148080
ring finger protein 19B
chr4_-_22335247 0.03 ENSDART00000192781
golgin B1
chr1_+_58242498 0.03 ENSDART00000149091
gamma-glutamyltransferase 1 like 2.2
chr15_-_14193926 0.03 ENSDART00000162707
polynucleotide kinase 3'-phosphatase
chr5_+_32882688 0.03 ENSDART00000008807
ENSDART00000185317
ribosomal protein L12
chr11_-_438492 0.03 ENSDART00000137121
ENSDART00000133784
NUF2, NDC80 kinetochore complex component, homolog
chr23_-_18982499 0.03 ENSDART00000012507
bcl2-like 1
chr4_+_31405646 0.03 ENSDART00000128732
si:rp71-5o12.3
chr9_+_20869166 0.03 ENSDART00000147892
WD repeat domain 3
chr24_-_28259127 0.03 ENSDART00000149589
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr11_+_22109887 0.03 ENSDART00000122136
si:dkey-91m3.1
chr7_+_59649399 0.03 ENSDART00000123520
ENSDART00000040771
ribosomal protein L34
chr12_-_28848015 0.03 ENSDART00000153200
si:ch211-194k22.8
chr4_+_65649267 0.03 ENSDART00000184068
si:dkey-205i10.1
chr5_+_36896933 0.03 ENSDART00000151984
serine/arginine-rich splicing factor 7a
chr11_-_438294 0.02 ENSDART00000040812
NUF2, NDC80 kinetochore complex component, homolog
chr4_+_44454270 0.02 ENSDART00000150482
si:dkeyp-100h4.4
chr25_-_14424406 0.02 ENSDART00000073609
protein arginine methyltransferase 7
chr23_+_27778670 0.02 ENSDART00000053863
lysine (K)-specific methyltransferase 2D
chr22_+_24645325 0.02 ENSDART00000159531
lysophosphatidic acid receptor 3
chr25_-_12730260 0.02 ENSDART00000171834
kelch domain containing 4
chr8_-_29658171 0.02 ENSDART00000147755
macrophage expressed 1, tandem duplicate 3
chr15_-_14194208 0.02 ENSDART00000188237
ENSDART00000183155
ENSDART00000165520
polynucleotide kinase 3'-phosphatase
chr5_+_56119975 0.02 ENSDART00000083137
mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
chr23_+_39346930 0.02 ENSDART00000102843
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr1_-_21599219 0.02 ENSDART00000148327
ADAMTS-like 7
chr1_+_15062 0.02 ENSDART00000169005
centrosomal protein 97
chr8_+_23485079 0.02 ENSDART00000026316
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr8_+_53120278 0.02 ENSDART00000125232
nuclear receptor subfamily 2, group C, member 2
chr11_+_24046179 0.02 ENSDART00000006703
MAF1 homolog, negative regulator of RNA polymerase III
chr24_-_13272842 0.02 ENSDART00000146790
ENSDART00000066703
retinol dehydrogenase 10a
chr23_+_39346774 0.02 ENSDART00000190985
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr14_+_23709134 0.02 ENSDART00000191162
ENSDART00000179754
ENSDART00000054266
glucosamine-6-phosphate deaminase 1
chr21_+_19062124 0.02 ENSDART00000134746
ribosomal protein L17
chr13_-_42530656 0.02 ENSDART00000084327
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated
chr4_-_65747476 0.02 ENSDART00000142421
si:dkey-28k24.2
chr1_+_25696798 0.02 ENSDART00000054228
lecithin retinol acyltransferase a
chr1_-_23294753 0.02 ENSDART00000013263
UDP-glucose 6-dehydrogenase
chr14_-_32486757 0.02 ENSDART00000148830
MCF.2 cell line derived transforming sequence a
chr12_-_22238004 0.02 ENSDART00000038310
ORMDL sphingolipid biosynthesis regulator 3
chr13_-_2112008 0.02 ENSDART00000110814
family with sequence similarity 83, member B
chr6_-_13114406 0.02 ENSDART00000188015
zgc:194469
chr19_+_40250682 0.02 ENSDART00000102888
cyclin-dependent kinase 6
chr20_-_38449903 0.02 ENSDART00000136303
inositol-trisphosphate 3-kinase B
chr8_-_23776399 0.02 ENSDART00000114800
si:ch211-163l21.4
chr14_-_9982603 0.02 ENSDART00000054687
interleukin 1 receptor accessory protein-like 2
chr22_+_8753092 0.02 ENSDART00000140720
si:dkey-182g1.2
chr17_+_43659940 0.02 ENSDART00000145738
ENSDART00000075619
2-aminoethanethiol (cysteamine) dioxygenase b
chr11_+_1608348 0.02 ENSDART00000162438
si:dkey-40c23.3
chr17_-_106291 0.02 ENSDART00000160738
Rho GTPase activating protein 11A
chr5_-_54554583 0.02 ENSDART00000158865
ENSDART00000158069
Sjogren syndrome nuclear autoantigen 1
chr4_+_17843717 0.02 ENSDART00000113507
apoptotic peptidase activating factor 1
chr17_-_8673278 0.02 ENSDART00000171850
ENSDART00000017337
ENSDART00000148504
ENSDART00000148808
C-terminal binding protein 2a
chr23_+_34321237 0.02 ENSDART00000173272
plexin A1a
chr3_+_32557615 0.02 ENSDART00000151608
paired box 10
chr17_+_27456804 0.02 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
cathepsin L.1
chr16_-_34258931 0.02 ENSDART00000145485
phosphatase and actin regulator 4b
chr23_-_35347714 0.02 ENSDART00000161770
ENSDART00000165615
copine family member IX
chr7_-_6357952 0.02 ENSDART00000173197
zgc:165555
chr3_+_4047789 0.02 ENSDART00000148498
si:dkeyp-52c3.5
chr17_-_31044803 0.02 ENSDART00000185941
ENSDART00000152016
echinoderm microtubule associated protein like 1
chr14_-_30876299 0.01 ENSDART00000180305
ubiquitin-like 3b
chr4_-_60312069 0.01 ENSDART00000167207
si:dkey-248e17.4
chr2_+_16652238 0.01 ENSDART00000091351
glycerol kinase 5 (putative)
chr1_+_45671687 0.01 ENSDART00000146101
mucolipin 1a
chr17_-_22552678 0.01 ENSDART00000079401
si:ch211-125o16.4
chr4_+_34126849 0.01 ENSDART00000162442
si:ch211-223g7.6
chr22_+_12770877 0.01 ENSDART00000044683
formimidoyltransferase cyclodeaminase
chr25_+_19485198 0.01 ENSDART00000156730
glutaminase like
chr7_+_20966434 0.01 ENSDART00000185570
ephrin-B3b
chr12_-_31457301 0.01 ENSDART00000043887
ENSDART00000148603
acyl-CoA synthetase long chain family member 5
chr19_-_17303500 0.01 ENSDART00000162355
splicing factor 3a, subunit 3
chr6_+_58832155 0.01 ENSDART00000144842
dynactin 2 (p50)
chr17_+_36627099 0.01 ENSDART00000154104
interphotoreceptor matrix proteoglycan 1b
chr16_+_24971717 0.01 ENSDART00000156958
formyl peptide receptor 1
chr17_-_8673567 0.01 ENSDART00000192714
ENSDART00000012546
C-terminal binding protein 2a
chr20_+_263056 0.01 ENSDART00000132669
tubulin, epsilon 1
chr4_+_77038392 0.01 ENSDART00000186818
si:dkey-172k15.6
chr23_-_26532696 0.01 ENSDART00000124811
ENSDART00000180274
si:dkey-205h13.2
chr1_-_28950366 0.01 ENSDART00000110270
PWP2 periodic tryptophan protein homolog (yeast)
chr7_+_7630409 0.01 ENSDART00000172934
chloride channel 3
chr19_+_31044487 0.01 ENSDART00000143494
ankyrin repeat and MYND domain containing 2b
chr4_+_54618332 0.01 ENSDART00000171824
si:ch211-227e10.2
chr13_-_48388726 0.01 ENSDART00000169473
F-box protein 11a
chr5_-_39171302 0.01 ENSDART00000020808
progestin and adipoQ receptor family member IIIa
chr19_+_32401278 0.01 ENSDART00000184353
ataxin 1a
chr7_-_18601206 0.01 ENSDART00000111636
si:ch211-119e14.2
chr2_-_32668668 0.01 ENSDART00000190450
poly-U binding splicing factor a
chr12_+_32199651 0.01 ENSDART00000153027
si:ch211-277e21.1
chr3_+_24134418 0.01 ENSDART00000156204
si:ch211-246i5.5
chr14_-_49859747 0.01 ENSDART00000169456
ENSDART00000164967
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr12_-_19279103 0.01 ENSDART00000186669
si:ch211-141o9.10
chr12_+_18744610 0.01 ENSDART00000153456
megakaryoblastic leukemia (translocation) 1b
chr15_-_8517555 0.01 ENSDART00000140213
neuronal PAS domain protein 1
chr3_+_32571929 0.01 ENSDART00000151025
si:ch73-248e21.1
chr3_-_29891456 0.01 ENSDART00000151677
ENSDART00000014021
solute carrier family 25, member 39
chr14_-_30876708 0.01 ENSDART00000147597
ubiquitin-like 3b
chr8_-_39859688 0.01 ENSDART00000019907
unc-119 homolog 1
chr16_-_49505275 0.01 ENSDART00000160784
SATB homeobox 1b
chr5_-_32882162 0.01 ENSDART00000085769
leucine rich repeat and sterile alpha motif containing 1
chr10_+_21807497 0.01 ENSDART00000164634
protocadherin 1 gamma 32
chr5_+_63767376 0.01 ENSDART00000138898
regulator of G protein signaling 3b
chr12_-_20362041 0.01 ENSDART00000184145
ENSDART00000105952
aquaporin 8a, tandem duplicate 2
chr12_+_19208338 0.01 ENSDART00000110415
SH3-domain binding protein 1
chr9_+_4378153 0.01 ENSDART00000191264
ENSDART00000182384
kalirin RhoGEF kinase a
chr3_+_13600714 0.01 ENSDART00000162124
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr3_-_26805455 0.01 ENSDART00000180648
phosphatidylinositol glycan anchor biosynthesis, class Q
chr4_-_13580348 0.01 ENSDART00000067160
opsin 1 (cone pigments), short-wave-sensitive 1
chr11_-_41130239 0.01 ENSDART00000173268
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr22_-_18240968 0.01 ENSDART00000027605
transmembrane protein 161A
chr18_-_7481036 0.01 ENSDART00000101292
si:dkey-238c7.16
chr24_-_5691956 0.01 ENSDART00000189112
deleted in autism 1b
chr7_-_34294613 0.01 ENSDART00000191632

chr17_-_7496341 0.01 ENSDART00000186907
si:ch211-278p9.3
chr20_+_23742574 0.01 ENSDART00000050559
SH3 domain containing ring finger 1
chr16_-_11766265 0.01 ENSDART00000141547
zgc:158701
chr9_+_22634073 0.01 ENSDART00000181822
ets variant 5a
chr10_-_10863936 0.01 ENSDART00000180568
NOTCH regulated ankyrin repeat protein a
chr17_-_42213822 0.01 ENSDART00000187904
ENSDART00000180029
NK2 homeobox 2a
chr17_-_32698503 0.01 ENSDART00000157175
ENSDART00000077439
potassium channel, subfamily K, member 2a
chr22_-_18241390 0.01 ENSDART00000083879
transmembrane protein 161A
chr5_-_33825465 0.01 ENSDART00000110645
DAB2 interacting protein b
chr2_-_36604589 0.00 ENSDART00000167352
T-cell receptor alpha/delta variable 41.0
chr23_+_4348479 0.00 ENSDART00000182425
v-myb avian myeloblastosis viral oncogene homolog-like 2a
chr21_+_27189490 0.00 ENSDART00000125349
BCL2 associated agonist of cell death a
chr15_-_47937204 0.00 ENSDART00000154705
si:ch1073-111c8.3
chr20_+_48782068 0.00 ENSDART00000159275
NK2 homeobox 2b
chr10_-_9086716 0.00 ENSDART00000140095
ADP-ribosylation factor-like 15b
chr10_+_8481660 0.00 ENSDART00000109559

chr4_+_15942075 0.00 ENSDART00000147964
si:dkey-117n7.2
chr22_+_19111444 0.00 ENSDART00000109655
fibroblast growth factor 22
chr1_-_38171648 0.00 ENSDART00000137451
ENSDART00000047159
high mobility group box 2a
chr1_+_31658011 0.00 ENSDART00000192203
polymerase (DNA directed), lambda
chr23_+_42254960 0.00 ENSDART00000102980
zinc finger, CCHC domain containing 11
chr13_-_13294847 0.00 ENSDART00000125883
ENSDART00000013534
fibroblast growth factor receptor 3
chr2_-_11648731 0.00 ENSDART00000080925
inositol monophosphatase domain containing 1
chr10_-_10864331 0.00 ENSDART00000122657
NOTCH regulated ankyrin repeat protein a
chr21_-_18991165 0.00 ENSDART00000012574
si:ch211-222n4.6
chr23_+_4348265 0.00 ENSDART00000136287
v-myb avian myeloblastosis viral oncogene homolog-like 2a
chr12_+_41348969 0.00 ENSDART00000171352
si:ch211-27e6.1
chr20_+_51478939 0.00 ENSDART00000149758
toll-like receptor 5a
chr5_-_33460959 0.00 ENSDART00000085636
si:ch211-182d3.1
chr19_+_10847118 0.00 ENSDART00000189784
apolipoprotein A-IV a
chr1_+_31657842 0.00 ENSDART00000057880
polymerase (DNA directed), lambda
chr20_+_27464721 0.00 ENSDART00000189552
kinesin family member 26Aa
chr1_+_29862074 0.00 ENSDART00000133905
ENSDART00000136786
ENSDART00000135252
propionyl CoA carboxylase, alpha polypeptide
chr4_+_23126558 0.00 ENSDART00000162859
MDM2 oncogene, E3 ubiquitin protein ligase
chr10_+_31244619 0.00 ENSDART00000145562
ENSDART00000184412
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr15_+_22722684 0.00 ENSDART00000156760
glutamate receptor, ionotropic, kainate 4
chr9_-_24970018 0.00 ENSDART00000026924
dynein, axonemal, heavy chain 7
chr17_-_42213285 0.00 ENSDART00000140549
NK2 homeobox 2a
chr10_+_573667 0.00 ENSDART00000110384
SMAD family member 4a
chr11_+_12879635 0.00 ENSDART00000182515
ENSDART00000081296
si:dkey-11m19.5
chr2_+_23731194 0.00 ENSDART00000155747
solute carrier family 22 member 13a
chr23_+_7505943 0.00 ENSDART00000135787
HCK proto-oncogene, Src family tyrosine kinase
chr24_+_33589667 0.00 ENSDART00000152097
dynein, axonemal, heavy chain 5 like
chr1_-_11291324 0.00 ENSDART00000091205
sidekick cell adhesion molecule 1b
chr8_-_22698651 0.00 ENSDART00000181411
IQ motif and Sec7 domain 2a
chr12_-_1361517 0.00 ENSDART00000188297

chr23_-_7826849 0.00 ENSDART00000157612
myelin transcription factor 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx2.4a+nkx2.4b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.0 0.0 GO:0050847 progesterone receptor signaling pathway(GO:0050847)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.0 0.0 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.0 GO:0031834 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)