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PRJNA207719: Tissue specific transcriptome profiling

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Results for nfixa+nfixb

Z-value: 1.11

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Transcription factors associated with nfixa+nfixb

Gene Symbol Gene ID Gene Info
ENSDARG00000043226 nuclear factor I/Xa
ENSDARG00000061836 nuclear factor I/Xb

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfixbdr11_v1_chr3_+_14768364_14768364-0.865.9e-02Click!
nfixadr11_v1_chr1_+_51896147_51896147-0.434.7e-01Click!

Activity profile of nfixa+nfixb motif

Sorted Z-values of nfixa+nfixb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_17672527 1.05 ENSDART00000148269
ENSDART00000137776
catechol-O-methyltransferase domain containing 1
chr1_-_33645967 0.90 ENSDART00000192758
claudin g
chr3_-_32541033 0.84 ENSDART00000151476
ENSDART00000055324
reticulocalbin 3, EF-hand calcium binding domain
chr4_-_8030583 0.82 ENSDART00000113628
si:ch211-240l19.8
chr23_+_19790962 0.73 ENSDART00000142228
filamin A, alpha (actin binding protein 280)
chr3_+_49021079 0.73 ENSDART00000162012
zgc:163083
chr22_+_38229321 0.69 ENSDART00000132670
ENSDART00000104504
si:ch211-284e20.8
chr22_+_5478353 0.68 ENSDART00000160596
tubulin polymerization promoting protein
chr14_+_29975268 0.67 ENSDART00000172985
cytochrome P450, family 4, subfamily V, polypeptide 7
chr14_-_25444774 0.67 ENSDART00000183448
solute carrier family 26 (anion exchanger), member 2
chr12_-_22524388 0.62 ENSDART00000020942
sex hormone-binding globulin
chr14_+_11458044 0.61 ENSDART00000186425
si:ch211-153b23.5
chr14_+_11457500 0.61 ENSDART00000169202
si:ch211-153b23.5
chr1_-_58900851 0.58 ENSDART00000183085
ENSDART00000188855
ENSDART00000182567
Danio rerio microfibril-associated glycoprotein 4-like (LOC100334800), transcript variant 2, mRNA.
chr19_+_14109348 0.58 ENSDART00000159015
zgc:175136
chr11_-_3629201 0.54 ENSDART00000136577
ENSDART00000132121
inter-alpha-trypsin inhibitor heavy chain 3a
chr2_-_14798295 0.53 ENSDART00000143430
ENSDART00000145869
si:ch73-366i20.1
chr22_-_15602760 0.53 ENSDART00000009054
tropomyosin 4a
chr22_+_25184459 0.53 ENSDART00000105308
si:ch211-226h8.4
chr3_-_39198113 0.52 ENSDART00000102690
zgc:154169
chr14_-_21064199 0.52 ENSDART00000172099
si:dkey-74k8.3
chr2_-_3437862 0.51 ENSDART00000053012
cytochrome P450, family 8, subfamily B, polypeptide 1
chr13_-_9895564 0.50 ENSDART00000169831
ENSDART00000142629
si:ch211-117n7.6
chr7_-_8416750 0.48 ENSDART00000181857
jacalin 1
chr22_+_19553390 0.48 ENSDART00000061739
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr16_-_22713152 0.47 ENSDART00000140953
ENSDART00000143836
si:ch211-105c13.3
chr1_-_54706039 0.46 ENSDART00000083633
exosome component 1
chr9_+_38292947 0.46 ENSDART00000146663
transcription factor CP2-like 1
chr15_-_31027112 0.45 ENSDART00000100185
lectin, galactoside-binding, soluble, 9 (galectin 9)-like 4
chr19_+_10603405 0.44 ENSDART00000151135
si:dkey-211g8.8
chr22_-_15602593 0.44 ENSDART00000036075
tropomyosin 4a
chr16_+_7697878 0.43 ENSDART00000104176
ENSDART00000172977
chemokine (C-C motif) receptor 11.1
chr2_-_41861040 0.43 ENSDART00000045763
kelch-like ECH-associated protein 1a
chr13_-_20381485 0.43 ENSDART00000131351
si:ch211-270n8.1
chr7_-_5207152 0.43 ENSDART00000172751
si:ch73-223f5.2
chr3_-_24681404 0.41 ENSDART00000161612

chr3_+_32416948 0.40 ENSDART00000157324
ENSDART00000154267
ENSDART00000186094
ENSDART00000155860
ENSDART00000156986
proline rich Gla (G-carboxyglutamic acid) 2
chr1_-_9988840 0.40 ENSDART00000144565
si:dkeyp-75b4.9
chr2_-_42375275 0.39 ENSDART00000026339
GTP binding protein 4
chr7_+_59649399 0.39 ENSDART00000123520
ENSDART00000040771
ribosomal protein L34
chr7_-_21928826 0.39 ENSDART00000088043
si:dkey-85k7.11
chr3_-_36750068 0.39 ENSDART00000173388
ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1
chr25_-_26018424 0.38 ENSDART00000089332
acyl-CoA synthetase bubblegum family member 1
chr15_-_28082310 0.38 ENSDART00000152620
dehydrogenase/reductase (SDR family) member 13a, duplicate 3
chr16_-_45209684 0.38 ENSDART00000184595
FXYD domain containing ion transport regulator 1 (phospholemman)
chr10_+_39263827 0.37 ENSDART00000172509
FAD-dependent oxidoreductase domain containing 1
chr6_-_9952103 0.36 ENSDART00000065475
zona pellucida glycoprotein 2, like 2
chr14_+_22076596 0.36 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
solute carrier family 43 (amino acid system L transporter), member 1a
chr25_-_26018240 0.36 ENSDART00000150800
acyl-CoA synthetase bubblegum family member 1
chr19_-_13962469 0.35 ENSDART00000159062
progestin and adipoQ receptor family member VII, a
chr16_+_38394371 0.34 ENSDART00000137954
CD83 molecule
chr1_-_999556 0.33 ENSDART00000170884
ENSDART00000172235
phosphoribosylglycinamide formyltransferase
chr4_-_52189449 0.33 ENSDART00000192426

chr22_+_38767780 0.32 ENSDART00000149499
alkaline phosphatase, intestinal, tandem duplicate 1
chr6_-_27108844 0.32 ENSDART00000073883
deoxythymidylate kinase (thymidylate kinase)
chr20_+_25581627 0.32 ENSDART00000030229
cytochrome P450, family 2, subfamily P, polypeptide 9
chr21_-_36619599 0.32 ENSDART00000065208
NOP16 nucleolar protein homolog (yeast)
chr16_+_27444098 0.32 ENSDART00000157690
inversin
chr19_-_12404590 0.32 ENSDART00000103703
finTRIM family, member 56
chr6_+_40437987 0.31 ENSDART00000136487
ghrelin/obestatin prepropeptide
chr14_+_15484544 0.31 ENSDART00000188649

chr20_+_26880668 0.31 ENSDART00000077769
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr6_-_15096556 0.30 ENSDART00000185327
four and a half LIM domains 2b
chr18_+_3037998 0.30 ENSDART00000185844
ENSDART00000162657
ribosomal protein S3
chr13_+_15682803 0.29 ENSDART00000188063

chr19_-_9786914 0.29 ENSDART00000181669
si:dkey-14o18.2
chr3_-_55139127 0.29 ENSDART00000115324
hemoglobin, alpha embryonic 1.3
chr4_-_8040436 0.28 ENSDART00000113033
si:ch211-240l19.6
chr6_+_39905021 0.28 ENSDART00000064904
endonuclease, polyU-specific
chr11_-_24016761 0.28 ENSDART00000153601
ENSDART00000067817
ENSDART00000170531
chitinase, acidic.3
chr3_-_22228602 0.28 ENSDART00000017750
myosin, light chain 4, alkali; atrial, embryonic
chr21_+_19858627 0.28 ENSDART00000147010
FYN binding protein b
chr11_+_14333441 0.27 ENSDART00000171969
polypyrimidine tract binding protein 1b
chr5_-_23878809 0.27 ENSDART00000160603
si:ch211-135f11.4
chr6_+_8630355 0.27 ENSDART00000161749
ENSDART00000193976
thrombospondin-type laminin G domain and EAR repeats a
chr2_-_51757328 0.27 ENSDART00000189286
si:ch211-9d9.1
chr1_+_1789357 0.27 ENSDART00000006449
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 2
chr11_-_11575070 0.27 ENSDART00000142208
zgc:110712
chr15_+_37986069 0.26 ENSDART00000156984
si:dkey-238d18.8
chr3_-_26921475 0.26 ENSDART00000130281
class II, major histocompatibility complex, transactivator
chr25_+_16194450 0.26 ENSDART00000141994
microtubule associated monooxygenase, calponin and LIM domain containing 2b
chr3_-_40976288 0.25 ENSDART00000193553
cytochrome P450, family 3, subfamily c, polypeptide 1
chr19_-_7225060 0.25 ENSDART00000133179
ENSDART00000151138
ENSDART00000104799
ENSDART00000128331
collagen, type XI, alpha 2
chr5_-_37103487 0.25 ENSDART00000149211
interleukin 13 receptor, alpha 2
chr25_-_30394746 0.25 ENSDART00000185346
si:ch211-93f2.1
chr11_-_11890001 0.25 ENSDART00000081544
WAS/WASL interacting protein family, member 2a
chr2_-_14793343 0.25 ENSDART00000132264
si:ch73-366i20.1
chr11_+_43740949 0.24 ENSDART00000189296

chr19_-_42556086 0.24 ENSDART00000051731
si:dkey-267n13.1
chr25_-_16581233 0.24 ENSDART00000155312
structural maintenance of chromosomes 1B
chr13_+_18545819 0.24 ENSDART00000101859
ENSDART00000110197
ENSDART00000136064
zgc:154058
chr9_+_15890558 0.24 ENSDART00000144032
si:dkey-14o1.20
chr15_+_38308421 0.24 ENSDART00000129941
si:dkey-24p1.6
chr2_-_36918709 0.23 ENSDART00000084876
zgc:153654
chr7_+_25049545 0.23 ENSDART00000173896
ENSDART00000173566
si:dkey-23i12.7
protein phosphatase 2, regulatory subunit B', beta
chr7_+_12835048 0.23 ENSDART00000016465
connexin 36.7
chr13_+_18321140 0.23 ENSDART00000180947
eukaryotic translation initiation factor 4E family member 1c
chr3_-_8130926 0.22 ENSDART00000189495
si:ch211-51i16.1
chr2_-_2642476 0.22 ENSDART00000124032
SERPINE1 mRNA binding protein 1b
chr21_-_25555355 0.22 ENSDART00000144228
si:dkey-17e16.9
chr6_+_32834760 0.22 ENSDART00000121562
cylindromatosis (turban tumor syndrome), like
chr1_-_9644630 0.22 ENSDART00000123725
ENSDART00000161164
UDP glucuronosyltransferase 5 family, polypeptide B3
chr16_+_48682309 0.22 ENSDART00000183957
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr8_+_48858132 0.22 ENSDART00000124737
ENSDART00000079644
tumor protein p73
chr5_-_10239079 0.22 ENSDART00000132739
si:ch73-42k18.1
chr14_+_40874608 0.22 ENSDART00000168448
si:ch211-106m9.1
chr4_+_37406676 0.22 ENSDART00000130981
si:ch73-134f24.1
chr7_+_61184551 0.22 ENSDART00000190788
zgc:194930
chr4_+_28997595 0.21 ENSDART00000133357
si:dkey-13e3.1
chr15_+_14154174 0.21 ENSDART00000161234
chloride channel accessory 5, tandem duplicate 1
chr2_+_15069011 0.21 ENSDART00000145893
calponin 3, acidic b
chr25_-_30429607 0.20 ENSDART00000162429
ENSDART00000176535
si:ch211-93f2.1
chr16_-_16619854 0.20 ENSDART00000150512
ENSDART00000191306
ENSDART00000181773
ENSDART00000183231
cytochrome P450, family 21, subfamily A, polypeptide 2
chr9_+_12890161 0.20 ENSDART00000146477
si:ch211-167j6.4
chr7_+_35238234 0.20 ENSDART00000178732
tubulin polymerization-promoting protein family member 3
chr6_-_49078263 0.20 ENSDART00000032982
solute carrier family 5 (iodide transporter), member 8-like
chr6_-_24301324 0.20 ENSDART00000171401

chr24_-_23998897 0.20 ENSDART00000130053
zmp:0000000991
chr3_+_34988670 0.19 ENSDART00000011319
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr4_+_70556298 0.19 ENSDART00000170985
si:dkey-11d20.1
chr19_-_7144548 0.19 ENSDART00000147177
ENSDART00000134850
proteasome subunit beta 8A
proteasome subunit beta 13a
chr7_-_34294613 0.19 ENSDART00000191632

chr8_-_43834442 0.19 ENSDART00000191927
adhesion G protein-coupled receptor D1
chr20_+_31985461 0.19 ENSDART00000191961

chr21_-_26558268 0.19 ENSDART00000065390

chr17_+_20589553 0.19 ENSDART00000154447
si:ch73-288o11.4
chr18_-_21177674 0.19 ENSDART00000060175
si:dkey-12e7.4
chr2_+_16191852 0.19 ENSDART00000152046
SH3-domain GRB2-like endophilin B1b
chr19_-_29832876 0.19 ENSDART00000005119
eukaryotic translation initiation factor 3, subunit I
chr19_+_30990815 0.18 ENSDART00000134645
syncoilin, intermediate filament protein
chr21_+_27448856 0.18 ENSDART00000100784
complement factor b-like
chr17_+_6382275 0.18 ENSDART00000056324

chr21_-_33126697 0.18 ENSDART00000189293
ENSDART00000084559

chr8_+_46536893 0.18 ENSDART00000124023
Pim proto-oncogene, serine/threonine kinase, related 187
chr3_-_34068044 0.18 ENSDART00000187926
immunoglobulin heavy variable 10-1
chr5_-_26181863 0.17 ENSDART00000098500
coiled-coil domain containing 125
chr23_+_16831063 0.17 ENSDART00000104782
zgc:173570
chr23_+_21414005 0.17 ENSDART00000144686
intermediate filament family orphan 2a
chr24_+_1294176 0.17 ENSDART00000106637
si:ch73-134f24.1
chr9_+_13999620 0.17 ENSDART00000143229
cd28-like molecule
chr15_+_5280858 0.17 ENSDART00000174242
odorant receptor, family E, subfamily 121, member 1
chr19_-_24163845 0.17 ENSDART00000133277
perforin 1.2
chr22_+_9918872 0.17 ENSDART00000177953
bloody fingers
chr18_+_618005 0.17 ENSDART00000189667
protogenin homolog a (Gallus gallus)
chr9_-_30190513 0.17 ENSDART00000137083
interphotoreceptor matrix proteoglycan 2a
chr7_+_61184104 0.16 ENSDART00000110671
zgc:194930
chr21_-_31207522 0.16 ENSDART00000191637
zgc:152891
chr13_+_50375800 0.16 ENSDART00000099537
cytochrome c oxidase subunit Vb 2
chr22_-_28653074 0.16 ENSDART00000154717
collagen, type VIII, alpha 1b
chr11_-_20956309 0.16 ENSDART00000188659

chr25_+_7494181 0.16 ENSDART00000165005
catalase
chr17_-_8886735 0.16 ENSDART00000121997
NK-lysin tandem duplicate 3
chr19_-_5264517 0.16 ENSDART00000001821
perforin 1.3
chr16_-_26727032 0.16 ENSDART00000177668
ring finger protein 41, like
chr21_+_15866522 0.15 ENSDART00000110728
glucosaminyl (N-acetyl) transferase 4, core 2, b
chr8_+_20880848 0.15 ENSDART00000134488
ENSDART00000138605
ENSDART00000192234
si:ch73-196i15.3
chr5_-_38179220 0.15 ENSDART00000147701
si:ch211-284e13.11
chr21_+_25335807 0.15 ENSDART00000146443
odorant receptor, family H, subfamily 132, member 2
chr10_-_17988779 0.15 ENSDART00000132206
ENSDART00000144841
si:dkey-242g16.2
chr17_+_37249736 0.15 ENSDART00000189686

chr25_+_10953351 0.14 ENSDART00000154050
major histocompatibility complex class I LDA
chr6_-_46782176 0.14 ENSDART00000185559
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 4
chr24_+_26432541 0.14 ENSDART00000105784
ENSDART00000122554
claudin 11b
chr7_+_73801377 0.14 ENSDART00000184051
si:ch73-252p3.1
chr17_-_33707589 0.14 ENSDART00000124788
si:dkey-84k17.2
chr5_+_45918680 0.14 ENSDART00000036242
ankyrin repeat and death domain containing 1B
chr17_+_16873417 0.14 ENSDART00000146276
iodothyronine deiodinase 2
chr4_-_72100774 0.14 ENSDART00000170099
solute carrier organic anion transporter family, member 1F1
chr15_+_5321612 0.14 ENSDART00000174345
odorant receptor, family A, subfamily 113, member 1
chr24_+_15655233 0.14 ENSDART00000143160
F-box protein 15
chr8_-_31416403 0.13 ENSDART00000098912
zinc finger protein 131
chr5_+_31965845 0.13 ENSDART00000112968
myosin IHb
chr4_+_51347000 0.13 ENSDART00000161859
si:dkeyp-82b4.3
chr3_-_8765165 0.13 ENSDART00000191131

chr23_-_20361971 0.13 ENSDART00000133373
si:rp71-17i16.5
chr23_+_28381260 0.13 ENSDART00000162722
zgc:153867
chr24_-_20369760 0.13 ENSDART00000185585
deleted in lung and esophageal cancer 1
chr2_-_24488652 0.13 ENSDART00000052067
insulin-like 3 (Leydig cell)
chr9_-_39968820 0.13 ENSDART00000100311
si:zfos-1425h8.1
chr7_+_21917857 0.12 ENSDART00000088041
UFM1-specific peptidase 1 (non-functional)
chr2_+_44518636 0.12 ENSDART00000153733
PAS domain containing serine/threonine kinase
chr24_+_21174851 0.12 ENSDART00000154940
ENSDART00000155977
ENSDART00000122762
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr8_-_20138054 0.12 ENSDART00000133141
ENSDART00000147634
ENSDART00000029939
regulatory factor X, 2 (influences HLA class II expression)
chr23_-_26880623 0.12 ENSDART00000038491
adenylate cyclase 6b
chr11_+_44579865 0.12 ENSDART00000173425
nidogen 1b
chr13_-_8815530 0.12 ENSDART00000122498
si:ch73-105b23.6
chr10_+_36345176 0.12 ENSDART00000099397
odorant receptor, family C, subfamily 105, member 1
chr22_+_10163901 0.12 ENSDART00000190468
ribonuclease P/MRP 14 subunit
chr16_-_17525322 0.12 ENSDART00000189720
chloride channel, voltage-sensitive 1b
chr14_-_9277152 0.12 ENSDART00000189048
ankyrin repeat and SOCS box-containing 12b
chr19_-_24443867 0.12 ENSDART00000163763
ENSDART00000043133
thrombospondin 3b
chr2_-_51330414 0.12 ENSDART00000186450
si:dkeyp-104b3.21
chr13_-_9024004 0.11 ENSDART00000169564
si:dkey-112g5.11
chr17_-_48743076 0.11 ENSDART00000173117
potassium channel, subfamily K, member 17
chr5_+_26121393 0.11 ENSDART00000002221
beta-carotene 15, 15-dioxygenase 2, like
chr7_-_59054322 0.11 ENSDART00000165390
charged multivesicular body protein 5b
chr15_+_31344472 0.11 ENSDART00000146695
ENSDART00000159182
ENSDART00000060125
odorant receptor, family D, subfamily 107, member 1
chr12_-_6880694 0.11 ENSDART00000171846
protocadherin-related 15b
chr11_-_1933793 0.10 ENSDART00000186850
Fas apoptotic inhibitory molecule 2b
chr2_-_37477654 0.10 ENSDART00000193921
death-associated protein kinase 3

Network of associatons between targets according to the STRING database.

First level regulatory network of nfixa+nfixb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.3 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468)
0.1 0.3 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1 0.5 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.1 0.4 GO:2000561 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 0.3 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 0.4 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.3 GO:0046083 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.1 0.2 GO:0019884 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 1.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.4 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.0 1.0 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0071962 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.0 0.2 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.3 GO:0032095 regulation of response to food(GO:0032095)
0.0 0.5 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.0 0.3 GO:0006032 chitin catabolic process(GO:0006032)
0.0 0.7 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.2 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.1 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.2 GO:0003160 endocardium morphogenesis(GO:0003160)
0.0 0.5 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.4 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0032608 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.3 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.1 GO:0046551 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.0 0.3 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.1 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962) regulation of polysaccharide biosynthetic process(GO:0032885)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016234 inclusion body(GO:0016234)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.5 GO:0019814 immunoglobulin complex(GO:0019814)
0.0 1.2 GO:0005884 actin filament(GO:0005884)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008397 sterol 12-alpha-hydroxylase activity(GO:0008397)
0.1 0.3 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.2 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.1 0.7 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.4 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) peptide-transporting ATPase activity(GO:0015440) TAP binding(GO:0046977)
0.0 0.3 GO:0043914 NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 1.0 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.0 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.5 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.0 0.2 GO:0004096 catalase activity(GO:0004096)
0.0 0.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.3 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.6 GO:0042562 hormone binding(GO:0042562)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis