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PRJNA207719: Tissue specific transcriptome profiling

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Results for nfil3-5

Z-value: 2.08

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Transcription factors associated with nfil3-5

Gene Symbol Gene ID Gene Info
ENSDARG00000094965 nuclear factor, interleukin 3 regulated, member 5
ENSDARG00000113345 nuclear factor, interleukin 3 regulated, member 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfil3-5dr11_v1_chr6_+_8172227_81722270.405.1e-01Click!

Activity profile of nfil3-5 motif

Sorted Z-values of nfil3-5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_38079261 2.89 ENSDART00000105662
C-reactive protein 1
chr25_+_34984333 2.84 ENSDART00000154760
coiled-coil domain containing 136b
chr5_+_37837245 2.31 ENSDART00000171617
ependymin
chr3_+_16612574 2.27 ENSDART00000104481
solute carrier family 17 (vesicular glutamate transporter), member 7a
chr21_-_22115136 2.08 ENSDART00000134715
ENSDART00000089246
ENSDART00000139789
ELMO/CED-12 domain containing 1
chr21_-_22114625 2.04 ENSDART00000177426
ENSDART00000135410
ELMO/CED-12 domain containing 1
chr14_+_33458294 1.99 ENSDART00000075278
ATPase Na+/K+ transporting subunit beta 4
chr23_+_37323962 1.99 ENSDART00000102881
family with sequence similarity 43, member B
chr25_+_15354095 1.84 ENSDART00000090397
KIAA1549-like a
chr21_-_43949208 1.83 ENSDART00000150983
calcium/calmodulin-dependent protein kinase II alpha
chr23_+_45579497 1.82 ENSDART00000110381
early growth response 4
chr21_-_43550120 1.76 ENSDART00000151627
si:ch73-362m14.2
chr17_-_20979077 1.70 ENSDART00000006676
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr3_-_28665291 1.68 ENSDART00000151670
F-box and leucine-rich repeat protein 16
chr3_-_46818001 1.65 ENSDART00000166505
ELAV like neuron-specific RNA binding protein 3
chr7_+_30787903 1.57 ENSDART00000174000
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr10_-_24371312 1.55 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr11_-_10770053 1.53 ENSDART00000179213
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr17_-_43466317 1.53 ENSDART00000155313
heat shock protein 4 like
chr7_+_38717624 1.51 ENSDART00000132522
synaptotagmin XIII
chr2_+_24177190 1.41 ENSDART00000099546
microtubule associated protein 4 like
chr19_+_23982466 1.39 ENSDART00000080673
synaptotagmin XIa
chr16_+_39146696 1.39 ENSDART00000121756
ENSDART00000084381
syntabulin (syntaxin-interacting)
chr22_-_354592 1.36 ENSDART00000155769
transmembrane protein 240b
chr5_-_22001003 1.36 ENSDART00000134393
ENSDART00000143878
Cdc42 guanine nucleotide exchange factor (GEF) 9a
chr5_-_21970881 1.34 ENSDART00000182907
Cdc42 guanine nucleotide exchange factor (GEF) 9a
chr4_-_5291256 1.30 ENSDART00000150864
si:ch211-214j24.9
chr20_-_40717900 1.30 ENSDART00000181663
connexin 43
chr11_+_30161699 1.28 ENSDART00000190504
cyclin-dependent kinase-like 5
chr8_+_47897734 1.27 ENSDART00000140266
mitofusin 2
chr1_-_8101495 1.27 ENSDART00000161938
si:dkeyp-9d4.3
chr1_-_14234076 1.26 ENSDART00000040049
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr21_-_42202792 1.26 ENSDART00000124708
gamma-aminobutyric acid (GABA) A receptor, alpha 6b
chr6_-_13187168 1.24 ENSDART00000193286
ENSDART00000188350
ENSDART00000150036
ENSDART00000149940
ADAM metallopeptidase domain 23a
chr4_-_5302866 1.24 ENSDART00000138590
si:ch211-214j24.9
chr1_-_53750522 1.23 ENSDART00000190755
v-akt murine thymoma viral oncogene homolog 3b
chr16_+_46111849 1.23 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr1_-_14233815 1.22 ENSDART00000044896
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr13_-_21688176 1.19 ENSDART00000063825
shadow of prion protein
chr12_-_26383242 1.18 ENSDART00000152941
ubiquitin specific peptidase 54b
chr5_+_1278092 1.15 ENSDART00000147972
ENSDART00000159783
dynamin 1a
chr5_-_41494831 1.14 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr25_-_11088839 1.10 ENSDART00000154748
synaptic vesicle glycoprotein 2Bb
chr22_-_11438627 1.07 ENSDART00000007649
MID1 interacting protein 1b
chr3_-_35602233 1.06 ENSDART00000055269
guanine nucleotide binding protein (G protein), gamma 13b
chr1_+_54673846 1.06 ENSDART00000145018
G protein-coupled receptor, class C, group 5, member Bb
chr22_-_3595439 1.05 ENSDART00000083308
protein tyrosine phosphatase, receptor type, s, a
chr9_-_18877597 1.00 ENSDART00000099446
potassium channel tetramerization domain containing 4
chr10_+_33895315 0.99 ENSDART00000142881
furry homolog b (Drosophila)
chr23_+_17800717 0.99 ENSDART00000122654
ENSDART00000044986
Rho family GTPase 1a
chr14_-_21618005 0.98 ENSDART00000043162
receptor accessory protein 2
chr4_+_3482312 0.97 ENSDART00000109044
glutamate receptor, metabotropic 8a
chr13_+_27314795 0.96 ENSDART00000128726
eukaryotic translation elongation factor 1 alpha 1a
chr21_-_12119711 0.96 ENSDART00000131538
CUGBP, Elav-like family member 4
chr8_-_39903803 0.96 ENSDART00000012391
calcium binding protein 1a
chr14_-_9199968 0.96 ENSDART00000146113
Cdc42 guanine nucleotide exchange factor (GEF) 9b
chr15_-_20939579 0.96 ENSDART00000152371
ubiquitin specific peptidase 2a
chr15_+_37559570 0.95 ENSDART00000085522
heat shock protein, alpha-crystallin-related, b6
chr5_-_55848358 0.94 ENSDART00000130891
calcium/calmodulin-dependent protein kinase IV
chr4_-_5302162 0.93 ENSDART00000177099
si:ch211-214j24.9
chr25_-_9805269 0.93 ENSDART00000192048
leucine rich repeat containing 4C
chr25_-_10564721 0.93 ENSDART00000154776
galanin/GMAP prepropeptide
chr6_+_41255485 0.92 ENSDART00000042683
ENSDART00000186013
Ca2+-dependent activator protein for secretion b
chr5_-_55848511 0.91 ENSDART00000183503
calcium/calmodulin-dependent protein kinase IV
chr24_+_18948665 0.89 ENSDART00000106186
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr19_-_5254699 0.88 ENSDART00000081951
syntaxin 1B
chr4_-_22671469 0.88 ENSDART00000050753
CD36 molecule (thrombospondin receptor)
chr3_+_33345348 0.87 ENSDART00000059262
membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2)
chr21_-_42007213 0.87 ENSDART00000188804
ENSDART00000092821
ENSDART00000165743
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr14_+_34971554 0.87 ENSDART00000184271
ring finger protein 145a
chr20_+_38201644 0.86 ENSDART00000022694
EH-domain containing 3
chr16_+_34493987 0.85 ENSDART00000138374
si:ch211-255i3.4
chr2_+_34967210 0.84 ENSDART00000141796
astrotactin 1
chr19_-_28367413 0.84 ENSDART00000079092
si:dkey-261i16.5
chr13_-_27675212 0.83 ENSDART00000141035
regulating synaptic membrane exocytosis 1a
chr18_-_39288894 0.83 ENSDART00000186216
mitogen-activated protein kinase 6
chr7_+_20535869 0.83 ENSDART00000078181
zgc:158423
chr14_-_21219659 0.83 ENSDART00000089867
protein phosphatase 2, regulatory subunit B, gamma b
chr18_-_898870 0.83 ENSDART00000151777
ENSDART00000062654
poly (ADP-ribose) polymerase family, member 6a
chr12_-_10315039 0.82 ENSDART00000152680
peptide YYb
chr10_-_17284055 0.82 ENSDART00000167464
G protein subunit alpha z
chr25_-_10565006 0.80 ENSDART00000130608
ENSDART00000190212
galanin/GMAP prepropeptide
chr7_-_38861741 0.80 ENSDART00000173629
ENSDART00000037361
ENSDART00000173953
PHD finger protein 21Aa
chr11_+_30161168 0.80 ENSDART00000157385
cyclin-dependent kinase-like 5
chr20_+_1121458 0.79 ENSDART00000064472
proline-rich nuclear receptor coactivator 1
chr3_-_33880951 0.79 ENSDART00000013228
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a
chr18_+_1703984 0.78 ENSDART00000114010
SLIT and NTRK-like family, member 3a
chr21_-_32467799 0.78 ENSDART00000007675
ENSDART00000133099
zgc:123105
chr14_-_30587814 0.78 ENSDART00000144912
ENSDART00000149714
transmembrane protein 265
chr11_+_6819050 0.78 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr7_+_38278860 0.77 ENSDART00000016265
low density lipoprotein receptor-related protein 3
chr9_+_17862858 0.76 ENSDART00000166566
diacylglycerol kinase, eta
chr1_-_5394752 0.76 ENSDART00000103724
ENSDART00000188453
Nedd4 family interacting protein 2
chr19_+_7549854 0.76 ENSDART00000138866
ENSDART00000151758
pre-B-cell leukemia homeobox interacting protein 1a
chr5_+_15350954 0.75 ENSDART00000140990
ENSDART00000137287
ENSDART00000061653
phosphatidylethanolamine binding protein 1
chr1_+_31864404 0.75 ENSDART00000075260
internexin neuronal intermediate filament protein, alpha b
chr7_-_32833153 0.75 ENSDART00000099871
ENSDART00000099872
solute carrier family 17 (vesicular glutamate transporter), member 6b
chr15_+_7992906 0.74 ENSDART00000090790
cell adhesion molecule 2b
chr3_+_37827373 0.74 ENSDART00000039517
acid-sensing (proton-gated) ion channel 2
chr7_-_6604623 0.74 ENSDART00000172874
potassium inwardly-rectifying channel, subfamily J, member 10a
chr5_-_40210447 0.74 ENSDART00000131323
si:dkey-193c22.1
chr5_+_38276582 0.73 ENSDART00000158532
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr4_+_3389866 0.73 ENSDART00000153834
synaptophysin-like 1
chr20_+_3934516 0.73 ENSDART00000165732
C-type lectin domain containing 11A
chr25_+_7784582 0.73 ENSDART00000155016
diacylglycerol kinase, zeta b
chr15_-_9272328 0.73 ENSDART00000172114
calmodulin 2a (phosphorylase kinase, delta)
chr19_-_12145765 0.73 ENSDART00000032474
poly A binding protein, cytoplasmic 1 b
chr3_-_21348478 0.72 ENSDART00000114906
family with sequence similarity 171, member A2a
chr15_-_20933574 0.72 ENSDART00000152648
ENSDART00000152448
ENSDART00000152244
ubiquitin specific peptidase 2a
chr21_-_21148623 0.71 ENSDART00000184364
ankyrin 1, erythrocytic b
chr9_+_46644633 0.70 ENSDART00000160285
solute carrier family 4 (anion exchanger), member 3
chr21_+_11923701 0.66 ENSDART00000109292
ubiquitin associated protein 2a
chr9_-_18742704 0.65 ENSDART00000145401
TSC22 domain family, member 1
chr2_+_34967022 0.65 ENSDART00000134926
astrotactin 1
chr17_+_29276544 0.64 ENSDART00000049399
ankyrin repeat domain 9
chr12_+_46960579 0.64 ENSDART00000149032
ornithine aminotransferase
chr22_+_4488454 0.64 ENSDART00000170620
cortexin 1
chr5_+_29784172 0.63 ENSDART00000139035
si:ch211-215c18.3
chr14_+_45406299 0.63 ENSDART00000173142
ENSDART00000112377
microtubule-associated protein 1 light chain 3 gamma, like
chr10_-_43611643 0.63 ENSDART00000134953
ENSDART00000134219
ENSDART00000138962
myocyte enhancer factor 2ca
chr15_-_26636826 0.62 ENSDART00000087632
solute carrier family 47 (multidrug and toxin extrusion), member 4
chr14_-_18671334 0.62 ENSDART00000182381
SLIT and NTRK-like family, member 4
chr25_-_13490744 0.62 ENSDART00000056721
lactate dehydrogenase D
chr10_+_21776911 0.62 ENSDART00000163077
ENSDART00000186093
protocadherin 1 gamma 22
chr20_-_1151265 0.60 ENSDART00000012376
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr22_+_15438872 0.60 ENSDART00000139800
glypican 5b
chr19_-_12145390 0.59 ENSDART00000143087
poly A binding protein, cytoplasmic 1 b
chr8_+_8532407 0.59 ENSDART00000169276
ENSDART00000138993
glutamate receptor, metabotropic 6a
chr10_-_26729930 0.59 ENSDART00000145532
fibroblast growth factor 13b
chr3_-_1204341 0.59 ENSDART00000089646
family with sequence similarity 234, member B
chr11_-_7078392 0.58 ENSDART00000112156
ENSDART00000188556
si:ch211-253b8.5
chr7_+_17716601 0.57 ENSDART00000173792
ENSDART00000080825
reticulon 3
chr8_+_25761654 0.57 ENSDART00000137899
ENSDART00000062403
transmembrane protein 9
chr21_-_32467099 0.57 ENSDART00000186354
zgc:123105
chr16_-_45069882 0.57 ENSDART00000058384
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr24_-_39772045 0.56 ENSDART00000087441
si:ch211-276f18.2
chr7_+_26629084 0.56 ENSDART00000101044
ENSDART00000173765
heat shock factor binding protein 1a
chr7_+_52761841 0.56 ENSDART00000111444
diphosphoinositol pentakisphosphate kinase 1a
chr22_+_10660140 0.55 ENSDART00000105835
ENSDART00000038511
tumor suppressor candidate 2b
chr17_-_21162821 0.55 ENSDART00000157283
abhydrolase domain containing 12
chr20_-_44576949 0.54 ENSDART00000148639
UBX domain protein 2A
chr18_-_1228688 0.54 ENSDART00000064403
neuroplastin b
chr15_+_23550890 0.54 ENSDART00000009796
ENSDART00000152720
si:dkey-31m14.7
chr8_-_32497815 0.54 ENSDART00000122359
si:dkey-164f24.2
chr10_-_26738209 0.54 ENSDART00000188590
fibroblast growth factor 13b
chr12_-_19862912 0.54 ENSDART00000145788
shisa family member 9a
chr7_-_38792543 0.53 ENSDART00000157416
si:dkey-23n7.10
chr9_-_43375205 0.53 ENSDART00000138436
zinc finger protein 385B
chr8_-_29851706 0.53 ENSDART00000149297
solute carrier family 20 (phosphate transporter), member 2
chr24_-_1341543 0.52 ENSDART00000169341
neuropilin 1a
chr7_+_22801465 0.52 ENSDART00000052862
ENSDART00000173633
RNA binding motif protein 4.1
chr11_+_41090440 0.52 ENSDART00000188287
PHD finger protein 13
chr5_-_21030934 0.52 ENSDART00000133461
ENSDART00000098667
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr19_+_42806812 0.51 ENSDART00000108775
ENSDART00000151653
upstream binding protein 1
chr8_+_8712446 0.51 ENSDART00000158674
ELK1, member of ETS oncogene family
chr2_+_37430917 0.51 ENSDART00000140558
polyhomeotic homolog 3 (Drosophila)
chr22_-_3449282 0.50 ENSDART00000136798
protein tyrosine phosphatase, receptor type, s, a
chr7_-_67842997 0.50 ENSDART00000169763
polyamine modulated factor 1 binding protein 1
chr2_+_38039857 0.50 ENSDART00000159951
calsequestrin 1a
chr14_+_36628131 0.49 ENSDART00000188625
ENSDART00000125345
si:dkey-237h12.3
chr24_-_41478917 0.48 ENSDART00000192192

chr6_-_53282572 0.48 ENSDART00000172615
ENSDART00000165036
RNA binding motif protein 5
chr19_-_20093341 0.47 ENSDART00000129917
membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)
chr11_-_3954691 0.47 ENSDART00000182041
polybromo 1
chr7_+_21887307 0.47 ENSDART00000052871
POP7 homolog, ribonuclease P/MRP subunit
chr19_+_21362553 0.47 ENSDART00000122002
teashirt zinc finger homeobox 1
chr16_-_21047872 0.46 ENSDART00000131582
chromobox homolog 3b
chr6_-_7726849 0.46 ENSDART00000151511
solute carrier family 25, member 38b
chr15_-_19128705 0.46 ENSDART00000152428
Rho GTPase activating protein 32a
chr6_-_18121075 0.45 ENSDART00000171072
si:dkey-237i9.1
chr23_+_37466967 0.45 ENSDART00000006436
PTEN induced putative kinase 1
chr20_-_44496245 0.45 ENSDART00000012229
FK506 binding protein 1b
chr10_-_23358357 0.45 ENSDART00000135475
cell adhesion molecule 2a
chr23_-_32194397 0.45 ENSDART00000184206
ENSDART00000166682
nuclear receptor subfamily 4, group A, member 1
chr25_+_33192404 0.45 ENSDART00000193592
zgc:171719
chr2_-_32486080 0.44 ENSDART00000110821
tetratricopeptide repeat domain 19
chr6_-_12314475 0.44 ENSDART00000156898
ENSDART00000157058
si:dkey-276j7.1
chr12_-_46959990 0.44 ENSDART00000084557
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr25_+_33192796 0.44 ENSDART00000125892
ENSDART00000121680
ENSDART00000014851
zgc:171719
chr8_-_32497581 0.43 ENSDART00000176298
ENSDART00000183340
si:dkey-164f24.2
chr21_-_1799265 0.43 ENSDART00000066623
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr6_-_30658755 0.43 ENSDART00000065215
ENSDART00000181302
leucine rich adaptor protein 1
chr7_-_32782430 0.43 ENSDART00000173808
growth arrest-specific 2b
chr24_+_21540842 0.43 ENSDART00000091529
WAS protein family, member 3b
chr18_-_21859019 0.43 ENSDART00000100885
neuritin 1-like a
chr9_-_18743012 0.43 ENSDART00000131626
TSC22 domain family, member 1
chr21_-_7687544 0.42 ENSDART00000134519
phosphodiesterase 8B
chr22_+_786556 0.42 ENSDART00000125347
cryptochrome circadian clock 1bb
chr20_-_36617313 0.42 ENSDART00000172395
ENSDART00000152856
enabled homolog (Drosophila)
chr19_-_868187 0.42 ENSDART00000186626
eomesodermin homolog a
chr15_+_17321218 0.41 ENSDART00000143796
clathrin, heavy chain b (Hc)
chr13_-_22766445 0.41 ENSDART00000140151
si:ch211-150i13.1
chr6_-_35472923 0.41 ENSDART00000185907
regulator of G protein signaling 8
chr4_-_77432218 0.40 ENSDART00000158683
solute carrier organic anion transporter family, member 1D1
chr11_+_19271557 0.40 ENSDART00000190559
prickle homolog 2b
chr6_+_9793495 0.40 ENSDART00000108524
amyotrophic lateral sclerosis 2b (juvenile)
chr15_-_22074315 0.39 ENSDART00000149830
dopamine receptor D2a
chr14_+_23717165 0.39 ENSDART00000006373
Nedd4 family interacting protein 1
chr1_-_45039726 0.39 ENSDART00000186188
SMU1, DNA replication regulator and spliceosomal factor b
chr22_+_15973122 0.38 ENSDART00000144545
ring finger and CCCH-type domains 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of nfil3-5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.3 1.4 GO:0060074 synapse maturation(GO:0060074)
0.3 0.8 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.2 2.8 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.2 0.6 GO:0036076 ligamentous ossification(GO:0036076)
0.2 0.6 GO:0006089 lactate metabolic process(GO:0006089)
0.2 1.3 GO:0048660 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.2 0.9 GO:0070208 protein heterotrimerization(GO:0070208)
0.2 0.5 GO:0014809 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 0.5 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.2 0.5 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 0.6 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.4 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.1 0.6 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.1 1.6 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.1 0.5 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.8 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 2.2 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.1 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.7 GO:0036268 swimming(GO:0036268)
0.1 0.5 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.1 0.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.3 GO:0046443 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.1 1.0 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.1 0.9 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 2.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 1.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.7 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.1 0.4 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 0.6 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.9 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 3.2 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 1.3 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 1.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.2 GO:0014808 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) sarcoplasmic reticulum calcium ion transport(GO:0070296) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.1 1.2 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.2 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.1 0.2 GO:0009097 isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097)
0.1 0.6 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.4 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.2 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:2000374 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.0 0.4 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 1.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.5 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.3 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.3 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.0 0.3 GO:0060420 regulation of heart growth(GO:0060420)
0.0 0.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.4 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.0 0.1 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0055071 manganese ion homeostasis(GO:0055071)
0.0 0.2 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.8 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.3 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 0.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 2.1 GO:0006414 translational elongation(GO:0006414)
0.0 0.3 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 1.2 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.0 0.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.9 GO:0007631 feeding behavior(GO:0007631)
0.0 0.3 GO:0043490 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.4 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 1.8 GO:0003146 heart jogging(GO:0003146)
0.0 0.3 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 1.0 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.6 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.2 GO:0035776 intraciliary transport involved in cilium morphogenesis(GO:0035735) pronephric proximal tubule development(GO:0035776)
0.0 1.8 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0045738 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.0 1.1 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.0 1.5 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.8 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.5 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.3 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.9 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0001113 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.3 GO:0055075 potassium ion homeostasis(GO:0055075)
0.0 0.1 GO:0010586 miRNA metabolic process(GO:0010586)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 1.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 4.1 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.1 GO:0046066 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) deoxyribonucleoside triphosphate biosynthetic process(GO:0009202) dGDP metabolic process(GO:0046066)
0.0 0.1 GO:0009092 homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) transsulfuration(GO:0019346)
0.0 0.1 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.0 2.0 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.8 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 0.5 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.6 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.5 GO:0006814 sodium ion transport(GO:0006814)
0.0 1.2 GO:0030865 cortical cytoskeleton organization(GO:0030865)
0.0 0.3 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.0 GO:2000379 positive regulation of reactive oxygen species metabolic process(GO:2000379)
0.0 1.4 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 0.4 GO:0043409 negative regulation of MAPK cascade(GO:0043409)
0.0 0.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 3.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 2.0 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 1.1 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.7 GO:0005883 neurofilament(GO:0005883)
0.1 0.5 GO:0097224 sperm connecting piece(GO:0097224)
0.1 3.1 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.4 GO:0071439 clathrin complex(GO:0071439)
0.1 1.3 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1 1.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.5 GO:0001650 fibrillar center(GO:0001650)
0.1 0.3 GO:0097268 cytoophidium(GO:0097268)
0.1 1.2 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 0.5 GO:0016586 RSC complex(GO:0016586)
0.1 3.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.8 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 1.3 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 2.1 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.7 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 3.7 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 4.2 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.9 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0044545 NSL complex(GO:0044545)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.4 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0099738 cell cortex region(GO:0099738)
0.0 0.3 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.8 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.2 1.2 GO:0050699 WW domain binding(GO:0050699)
0.2 1.6 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.2 1.6 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 0.9 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.2 0.8 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.2 2.1 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.6 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.6 GO:0033857 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 6.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.1 0.3 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.1 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 2.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.3 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.1 0.3 GO:0004061 arylformamidase activity(GO:0004061)
0.1 0.7 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.6 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.1 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.8 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.2 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 1.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 1.4 GO:0019894 kinesin binding(GO:0019894)
0.1 1.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 2.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.7 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 1.0 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.0 2.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.6 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.0 0.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.5 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.6 GO:0008483 transaminase activity(GO:0008483)
0.0 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.3 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 2.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.6 GO:0044325 ion channel binding(GO:0044325)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.8 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 4.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 4.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.6 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 4.9 GO:0003924 GTPase activity(GO:0003924)
0.0 0.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 1.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 1.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.4 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.8 REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.1 1.6 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation