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PRJNA207719: Tissue specific transcriptome profiling

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Results for myf6

Z-value: 1.12

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Transcription factors associated with myf6

Gene Symbol Gene ID Gene Info
ENSDARG00000029830 myogenic factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
myf6dr11_v1_chr4_+_21717793_21717793-0.365.5e-01Click!

Activity profile of myf6 motif

Sorted Z-values of myf6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_69619 0.92 ENSDART00000164425
MANSC domain containing 1
chr17_-_7861219 0.90 ENSDART00000148604
spectrin repeat containing, nuclear envelope 1b
chr11_-_101758 0.80 ENSDART00000173015
engulfment and cell motility 2
chr12_+_24562667 0.70 ENSDART00000056256
neurexin 1a
chr12_-_11570 0.70 ENSDART00000186179
shisa family member 6
chr1_-_625875 0.56 ENSDART00000167331
amyloid beta (A4) precursor protein a
chr25_+_34888886 0.56 ENSDART00000035245
spire-type actin nucleation factor 2
chr9_-_296169 0.56 ENSDART00000165228
kinesin family member 5A, a
chr7_+_25323742 0.52 ENSDART00000110347
cytochrome P450, family 26, subfamily b, polypeptide 1
chr21_+_18353703 0.52 ENSDART00000181396
ENSDART00000166359
si:ch73-287m6.1
chr23_+_44745317 0.51 ENSDART00000165654
ATPase Na+/K+ transporting subunit beta 2a
chr23_+_2714949 0.51 ENSDART00000105284
nuclear receptor coactivator 6
chr17_-_6730247 0.51 ENSDART00000031091
visinin-like 1b
chr13_+_27951688 0.50 ENSDART00000050303
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr17_-_4318393 0.49 ENSDART00000167995
ENSDART00000153824
N-ethylmaleimide-sensitive factor attachment protein, beta a
chr9_+_49727611 0.48 ENSDART00000110069
cysteine and serine rich nuclear protein 3
chr6_-_6775821 0.47 ENSDART00000141126
ENSDART00000106610
coiled-coil domain containing 85A, like
chr8_-_4596662 0.47 ENSDART00000138199
septin 5a
chr15_+_4632782 0.47 ENSDART00000156012
si:dkey-35i13.1
chr8_-_6877390 0.46 ENSDART00000170883
ENSDART00000005321
neurofilament, light polypeptide b
chr19_-_20113696 0.45 ENSDART00000188813
neuropeptide Y
chr3_-_1317290 0.44 ENSDART00000047094

chr20_-_32112818 0.44 ENSDART00000142653
glutamate receptor, metabotropic 1a
chr9_+_4429593 0.44 ENSDART00000184855

chr15_-_1651766 0.43 ENSDART00000127396
protein phosphatase, Mg2+/Mn2+ dependent, 1Lb
chr19_-_26869103 0.42 ENSDART00000089699
proline-rich transmembrane protein 1
chr25_+_34889061 0.42 ENSDART00000136226
spire-type actin nucleation factor 2
chr15_+_47161917 0.42 ENSDART00000167860
growth associated protein 43
chr21_-_45588720 0.41 ENSDART00000186642
ENSDART00000189531

chr16_+_7626535 0.41 ENSDART00000182670
ENSDART00000065514
ENSDART00000150212
syntaxin 12, like
chr12_+_31729075 0.41 ENSDART00000152973
si:dkey-49c17.3
chr19_+_206835 0.40 ENSDART00000161137
sodium channel, voltage-gated, type I, beta b
chr20_-_40319890 0.39 ENSDART00000075112
clavesin 2
chr21_-_20939488 0.39 ENSDART00000039043
regulator of G protein signaling 7 binding protein b
chr5_+_32162684 0.39 ENSDART00000134472
TAO kinase 3b
chr3_-_28075756 0.39 ENSDART00000122037
RNA binding fox-1 homolog 1
chr16_+_39146696 0.39 ENSDART00000121756
ENSDART00000084381
syntabulin (syntaxin-interacting)
chr10_+_466926 0.39 ENSDART00000145220
ARVCF, delta catenin family member a
chr16_-_13730152 0.39 ENSDART00000138772
tweety family member 1
chr20_+_22681066 0.39 ENSDART00000143286
ligand of numb-protein X 1
chr16_-_31188715 0.38 ENSDART00000058829
scratch family zinc finger 1b
chr8_+_54202554 0.38 ENSDART00000020569
cysteine-rich with EGF-like domains 1b
chr8_+_54081819 0.38 ENSDART00000005857
ENSDART00000161795
prickle homolog 2a
chr6_+_58549080 0.38 ENSDART00000180117
stathmin-like 3
chr6_+_48618512 0.36 ENSDART00000111190
si:dkey-238f9.1
chr18_-_39787040 0.36 ENSDART00000169916
Dmx-like 2
chr8_-_14052349 0.36 ENSDART00000135811
ATPase plasma membrane Ca2+ transporting 3a
chr7_-_34413392 0.36 ENSDART00000173673
ENSDART00000047208
ENSDART00000174546
MAP-kinase activating death domain
chr16_+_20738740 0.36 ENSDART00000079343
JAZF zinc finger 1b
chr6_-_14146979 0.36 ENSDART00000089564
calcium channel, voltage-dependent, beta 4b subunit
chr20_-_28768109 0.35 ENSDART00000114611
ENSDART00000182443
signal-induced proliferation-associated 1 like 1
chr2_-_44280061 0.35 ENSDART00000136818
myelin protein zero
chr12_+_42436328 0.35 ENSDART00000167324
early B cell factor 3a
chr16_+_36768674 0.35 ENSDART00000169208
ENSDART00000180470
si:ch73-215d9.1
chr3_-_56924654 0.34 ENSDART00000157038
HID1 domain containing a
chr6_-_13308813 0.34 ENSDART00000065372
potassium inwardly-rectifying channel, subfamily J, member 3b
chr18_+_15876385 0.34 ENSDART00000142527
early endosome antigen 1
chr21_+_5209716 0.34 ENSDART00000102539
ENSDART00000053148
ENSDART00000102536
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr8_+_16004154 0.34 ENSDART00000134787
ENSDART00000172510
ENSDART00000141173
ELAV like neuron-specific RNA binding protein 4
chr25_-_518656 0.34 ENSDART00000156421
myosin IXAb
chr17_+_50973017 0.34 ENSDART00000098082

chr17_+_27176243 0.34 ENSDART00000162527
si:ch211-160f23.7
chr7_-_69521481 0.34 ENSDART00000148465
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr16_-_13662514 0.33 ENSDART00000146348
shisa family member 7a
chr15_-_3094516 0.33 ENSDART00000179719
SLIT and NTRK-like family, member 5a
chr3_+_22935183 0.33 ENSDART00000157378
histone deacetylase 5
chr19_+_32979132 0.33 ENSDART00000169469
ENSDART00000171782
ENSDART00000180705
ENSDART00000179326
ENSDART00000193791
spire-type actin nucleation factor 1a
chr8_-_22639794 0.33 ENSDART00000188029
IQ motif and Sec7 domain 2a
chr5_+_28398449 0.33 ENSDART00000165292
NMDA receptor synaptonuclear signaling and neuronal migration factor b
chr10_+_15777258 0.33 ENSDART00000140511
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr12_+_1139690 0.33 ENSDART00000160442

chr10_+_45128375 0.33 ENSDART00000164805
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr8_+_104114 0.32 ENSDART00000172101
synuclein, alpha interacting protein
chr9_+_51891 0.32 ENSDART00000163529
zgc:158316
chr25_-_3503458 0.32 ENSDART00000173269
si:ch211-272n13.7
chr10_-_2527342 0.32 ENSDART00000184168

chr17_-_29119362 0.32 ENSDART00000104204
forkhead box G1a
chr23_+_4288964 0.32 ENSDART00000138408
l(3)mbt-like 1 (Drosophila)
chr23_+_19558574 0.32 ENSDART00000137811
ATPase H+ transporting accessory protein 1 like b
chr19_+_30633453 0.32 ENSDART00000052124
family with sequence similarity 49, member A-like
chr3_-_36260102 0.32 ENSDART00000126588
Rac family small GTPase 3a
chr25_+_15841670 0.32 ENSDART00000049992
synaptotagmin IXb
chr7_-_59589547 0.32 ENSDART00000008554
ENSDART00000101731
La ribonucleoprotein domain family, member 7
chr3_-_36115339 0.32 ENSDART00000187406
ENSDART00000123505
ENSDART00000151775
RAB11 family interacting protein 4 (class II) a
chr12_+_24561832 0.32 ENSDART00000088159
neurexin 1a
chr19_-_5812319 0.32 ENSDART00000114472
si:ch211-264f5.8
chr22_-_3595439 0.31 ENSDART00000083308
protein tyrosine phosphatase, receptor type, s, a
chr15_+_30917282 0.31 ENSDART00000129474
oligodendrocyte myelin glycoprotein b
chr3_-_21280373 0.31 ENSDART00000003939
synaptogyrin 1a
chr21_-_30545121 0.31 ENSDART00000019199
RAB39B, member RAS oncogene family a
chr4_-_11163112 0.31 ENSDART00000188854
protein arginine methyltransferase 8b
chr23_-_24190712 0.30 ENSDART00000139514
anoctamin 11
chr17_-_11329959 0.30 ENSDART00000015418
interferon regulatory factor 2 binding protein-like
chr2_+_22702488 0.30 ENSDART00000076647
kinesin family member 1Ab
chr18_-_85294 0.30 ENSDART00000044387
GA binding protein transcription factor, beta subunit 1
chr13_+_27073901 0.30 ENSDART00000146227
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr20_+_18551657 0.30 ENSDART00000147001
si:dkeyp-72h1.1
chr22_+_5106751 0.30 ENSDART00000138967
ataxia, cerebellar, Cayman type a
chr1_+_9886991 0.29 ENSDART00000135702
regulator of G protein signaling 11
chr10_+_15777064 0.29 ENSDART00000114483
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr5_+_57320113 0.29 ENSDART00000036331
ATPase H+ transporting V1 subunit G1
chr21_+_28958471 0.29 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr20_-_18736281 0.29 ENSDART00000142837
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr21_+_5209476 0.29 ENSDART00000146400
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr6_-_32999646 0.29 ENSDART00000159510
adenylate cyclase activating polypeptide 1b (pituitary) receptor type I
chr13_-_11644806 0.29 ENSDART00000169953
dynactin 1b
chr3_+_46724528 0.29 ENSDART00000181358
phosphodiesterase 4A, cAMP-specific
chr21_+_33249478 0.29 ENSDART00000169972
si:ch211-151g22.1
chr9_+_4306122 0.29 ENSDART00000193722
ENSDART00000190521
kalirin RhoGEF kinase a
chr12_-_4756478 0.29 ENSDART00000152181
microtubule-associated protein tau a
chr19_+_32979331 0.29 ENSDART00000078066
spire-type actin nucleation factor 1a
chr17_-_39786222 0.29 ENSDART00000154515
Pim proto-oncogene, serine/threonine kinase, related 62
chr6_-_49159207 0.29 ENSDART00000041942
tetraspanin 2a
chr13_-_16191674 0.29 ENSDART00000147868
von Willebrand factor C domain containing 2
chr19_-_8604429 0.29 ENSDART00000151165
tripartite motif containing 46b
chr24_+_41940299 0.28 ENSDART00000022349
erythrocyte membrane protein band 4.1-like 3a
chr9_-_31747106 0.28 ENSDART00000048469
ENSDART00000145204
ENSDART00000186889
sodium leak channel, non-selective
chr10_-_135432 0.28 ENSDART00000081978
potassium voltage-gated channel subfamily J member 6
chr23_+_40461411 0.28 ENSDART00000184223
SOGA family member 3b
chr14_+_28518349 0.28 ENSDART00000159961
stromal antigen 2b
chr21_-_15929041 0.28 ENSDART00000080693
LIM homeobox 5
chr13_+_421231 0.28 ENSDART00000188212
ENSDART00000017854
leucine-rich, glioma inactivated 1a
chr7_-_20756013 0.28 ENSDART00000185259
chromodomain helicase DNA binding protein 3
chr5_+_62052538 0.28 ENSDART00000141574
si:dkey-35m8.1
chr25_+_12640211 0.28 ENSDART00000165108
junctophilin 3
chr8_+_53344726 0.28 ENSDART00000184395
ENSDART00000170212

chr3_-_19133003 0.28 ENSDART00000145215
glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca
chr25_-_3503164 0.28 ENSDART00000191477
ENSDART00000186345
ENSDART00000180199
si:ch211-272n13.7
chr17_-_200316 0.27 ENSDART00000190561

chr10_-_625441 0.27 ENSDART00000171171
regulatory factor X, 3 (influences HLA class II expression)
chr23_-_18668836 0.27 ENSDART00000138792
ENSDART00000051182
Rho GTPase activating protein 4b
chr14_-_33177935 0.27 ENSDART00000180583
ENSDART00000078856
discs, large homolog 3 (Drosophila)
chr10_+_21804772 0.27 ENSDART00000162194
protocadherin 1 gamma 31
chr9_+_55056310 0.27 ENSDART00000047080
G protein-coupled receptor 143
chr18_-_13360106 0.27 ENSDART00000091512
c-Maf inducing protein
chr9_+_49712868 0.27 ENSDART00000192969
ENSDART00000183310
cysteine and serine rich nuclear protein 3
chr7_+_30988570 0.27 ENSDART00000180613
ENSDART00000185625
tight junction protein 1a
chr19_-_34063567 0.27 ENSDART00000157815
ENSDART00000183907
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr5_-_38384755 0.27 ENSDART00000188573
ENSDART00000051233
misshapen-like kinase 1
chr13_-_36911118 0.26 ENSDART00000048739
tripartite motif containing 9
chr8_-_1255321 0.26 ENSDART00000149605
cell division cycle 14B
chr6_+_34512313 0.26 ENSDART00000102554
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr20_+_52774730 0.26 ENSDART00000014606
phosphatase and actin regulator 1
chr5_+_36781732 0.26 ENSDART00000087191
MAP/microtubule affinity-regulating kinase 4a
chr8_+_52788997 0.26 ENSDART00000169198
adhesion G protein-coupled receptor D2
chr5_-_64203101 0.26 ENSDART00000029364
adenylate kinase 5, like
chr6_+_58543336 0.26 ENSDART00000157018
stathmin-like 3
chr21_-_43040780 0.25 ENSDART00000187037
janus kinase and microtubule interacting protein 2
chr3_+_29714775 0.25 ENSDART00000041388
calcium channel, voltage-dependent, gamma subunit 2a
chr7_+_63325819 0.25 ENSDART00000085612
ENSDART00000161436
protocadherin 7b
chr18_+_907266 0.25 ENSDART00000171729
pyruvate kinase M1/2a
chr24_-_21471389 0.25 ENSDART00000109848
ATPase phospholipid transporting 8A2
chr20_+_48100261 0.25 ENSDART00000158604
XK related 5a
chr23_-_21453614 0.25 ENSDART00000079274
hairy-related 4, tandem duplicate 1
chr4_+_90048 0.25 ENSDART00000166440
low density lipoprotein receptor-related protein 6
chr12_-_17810543 0.25 ENSDART00000090484
tectonin beta-propeller repeat containing 1a
chr22_+_24715282 0.25 ENSDART00000088027
ENSDART00000189054
ENSDART00000140430
synovial sarcoma, X breakpoint 2 interacting protein b
chr15_-_12500938 0.25 ENSDART00000159627
sodium channel, voltage-gated, type IV, beta a
chr7_-_31932723 0.25 ENSDART00000014843
brain-derived neurotrophic factor
chr4_+_3482312 0.25 ENSDART00000109044
glutamate receptor, metabotropic 8a
chr16_-_9980402 0.25 ENSDART00000066372
inhibitor of DNA binding 4
chr25_+_33849647 0.25 ENSDART00000121449
RAR-related orphan receptor A, paralog a
chr7_+_67486807 0.25 ENSDART00000159989
copine VII
chr7_+_50109239 0.25 ENSDART00000021605
si:dkey-6l15.1
chr23_-_7125494 0.25 ENSDART00000111929
solute carrier organic anion transporter family, member 4A1
chr25_-_32869794 0.25 ENSDART00000162784
transmembrane protein 266
chr5_-_46273938 0.25 ENSDART00000080033
si:ch211-130m23.3
chr5_+_42381273 0.24 ENSDART00000142387
Pim proto-oncogene, serine/threonine kinase, related 58
chr19_-_28360033 0.24 ENSDART00000186994
si:dkey-261i16.5
chr4_-_9764767 0.24 ENSDART00000164328
ENSDART00000147699
microtubule associated monooxygenase, calponin and LIM domain containing 3b
chr3_-_19091024 0.24 ENSDART00000188485
ENSDART00000110554
glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca
chr5_+_54685175 0.24 ENSDART00000115016
pro-melanin-concentrating hormone, like
chr14_-_33454595 0.24 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
transmembrane protein 255A
chr5_-_2636078 0.24 ENSDART00000122274
citron rho-interacting serine/threonine kinase a
chr11_+_4026229 0.24 ENSDART00000041417
calcium/calmodulin-dependent protein kinase Ib
chr2_-_30693742 0.24 ENSDART00000090292
catenin (cadherin-associated protein), delta 2b
chr6_+_41255485 0.24 ENSDART00000042683
ENSDART00000186013
Ca2+-dependent activator protein for secretion b
chr14_-_2348917 0.24 ENSDART00000159004
si:ch73-233f7.8
chr18_+_39028417 0.24 ENSDART00000148428
myosin VAa
chr10_+_24504292 0.24 ENSDART00000090059
microtubule associated tumor suppressor candidate 2a
chr13_-_7766758 0.24 ENSDART00000171831
H2A histone family, member Y2
chr12_-_6551681 0.24 ENSDART00000145413
si:ch211-253p2.2
chr14_-_4043818 0.24 ENSDART00000179870
sorting nexin 25
chr7_-_23563092 0.24 ENSDART00000132275
G protein-coupled receptor 185 b
chr4_-_4706893 0.24 ENSDART00000093005

chr18_+_9493720 0.24 ENSDART00000053125
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr4_-_18201622 0.24 ENSDART00000133509
ankyrin repeat and sterile alpha motif domain containing 1B
chr21_-_21373242 0.23 ENSDART00000079629
protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative)
chr6_-_30954268 0.23 ENSDART00000154523
phosphodiesterase 4B, cAMP-specific a
chr14_+_146857 0.23 ENSDART00000122521

chr8_-_25011157 0.23 ENSDART00000078795
adenosylhomocysteinase-like 1
chr9_-_19366538 0.23 ENSDART00000138431
zgc:152951
chr17_-_14726824 0.23 ENSDART00000162947
si:ch73-305o9.3
chr21_+_34167178 0.23 ENSDART00000158308
transient receptor potential cation channel, subfamily C, member 5b
chr5_-_13766651 0.23 ENSDART00000134064
MAX dimerization protein 1
chr1_+_39387876 0.23 ENSDART00000084891
ENSDART00000148701
teneurin transmembrane protein 3
chr16_+_25011994 0.23 ENSDART00000157312
zinc finger protein 1035
chr1_+_37195919 0.23 ENSDART00000159684
ENSDART00000172742
ENSDART00000158395
doublecortin-like kinase 2a
chr9_+_23511913 0.23 ENSDART00000137759
contactin associated protein-like 5a
chr19_+_31404686 0.23 ENSDART00000078459
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of myf6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 GO:0097106 postsynaptic density organization(GO:0097106)
0.2 1.6 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.2 0.5 GO:0035992 tendon formation(GO:0035992)
0.1 0.6 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.5 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.4 GO:1901546 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.1 1.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.5 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.1 0.3 GO:1900182 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 0.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 0.4 GO:0060074 synapse maturation(GO:0060074)
0.1 0.5 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.1 0.4 GO:0006972 hyperosmotic response(GO:0006972)
0.1 0.3 GO:0016264 gap junction assembly(GO:0016264)
0.1 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.2 GO:1901017 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 0.2 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.2 GO:0060959 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.1 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.2 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.2 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.1 0.4 GO:0086091 regulation of heart rate by cardiac conduction(GO:0086091)
0.1 0.4 GO:0043584 nose development(GO:0043584)
0.1 0.2 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.0 0.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.2 GO:1904353 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.0 1.2 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.4 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.1 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.0 0.2 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.0 0.6 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.0 0.5 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.1 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.1 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.0 0.3 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.0 0.1 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.4 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.0 0.3 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.0 0.2 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0001207 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.1 GO:0006844 acyl carnitine transport(GO:0006844)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.1 GO:0009098 leucine biosynthetic process(GO:0009098)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.5 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.2 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.0 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.1 GO:0098921 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.4 GO:0003307 regulation of Wnt signaling pathway involved in heart development(GO:0003307)
0.0 0.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.1 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:1900136 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.0 0.4 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.1 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0030328 prenylated protein catabolic process(GO:0030327) prenylcysteine catabolic process(GO:0030328) prenylcysteine metabolic process(GO:0030329)
0.0 0.3 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.1 GO:0044650 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.0 0.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.4 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.5 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.4 GO:1900151 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.3 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.1 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.2 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.1 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.2 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.1 GO:0014909 smooth muscle cell migration(GO:0014909)
0.0 0.1 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 1.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.3 GO:0035269 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.6 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.1 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.0 0.9 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.4 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.3 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
0.0 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 1.0 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.4 GO:0043507 activation of JUN kinase activity(GO:0007257) regulation of JUN kinase activity(GO:0043506) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.0 0.1 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:1903504 regulation of spindle checkpoint(GO:0090231) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.1 GO:0044108 calcitriol biosynthetic process from calciol(GO:0036378) vitamin D biosynthetic process(GO:0042368) cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.0 0.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.8 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.0 0.4 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.2 GO:0015813 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.3 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.7 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.0 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0051350 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclic nucleotide metabolic process(GO:0030800) negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350) negative regulation of purine nucleotide biosynthetic process(GO:1900372)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.6 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.0 0.2 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.1 GO:0061549 sympathetic ganglion development(GO:0061549)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 0.4 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0035094 response to nicotine(GO:0035094)
0.0 0.1 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.0 0.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.0 GO:0033632 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.1 GO:0090317 negative regulation of intracellular protein transport(GO:0090317)
0.0 0.0 GO:0039535 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.0 0.5 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.1 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.0 0.3 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.1 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.0 0.2 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 0.3 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.1 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.0 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) anchored component of the cytoplasmic side of the plasma membrane(GO:0098753)
0.1 0.5 GO:0005883 neurofilament(GO:0005883)
0.1 0.4 GO:0043291 RAVE complex(GO:0043291)
0.1 0.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.4 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 1.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.8 GO:0043209 myelin sheath(GO:0043209)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.1 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.0 0.1 GO:0070390 transcription export complex 2(GO:0070390)
0.0 0.0 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.0 GO:0030426 growth cone(GO:0030426)
0.0 0.8 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.7 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:1990071 TRAPPII protein complex(GO:1990071)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.0 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.5 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.7 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.0 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0099569 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
0.0 0.1 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.7 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.1 0.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.6 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.4 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.2 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.3 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.3 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.3 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.3 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.4 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0001735 prenylcysteine oxidase activity(GO:0001735)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.4 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.6 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0005163 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0031073 vitamin D3 25-hydroxylase activity(GO:0030343) cholesterol 26-hydroxylase activity(GO:0031073)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 1.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.0 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.0 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.0 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.0 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.0 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.5 GO:0044325 ion channel binding(GO:0044325)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.0 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.3 GO:0016208 AMP binding(GO:0016208)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.6 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 0.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 1.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.1 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.1 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide