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PRJNA207719: Tissue specific transcriptome profiling
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Results for mybl2b
Z-value: 1.59
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Transcription factors associated with mybl2b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| mybl2b | dr11_v1_chr11_+_1551603_1551663 | 0.50 | 3.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_-_2380173 Show fit | 1.28 |
ENSDART00000177727
|
nucleosome assembly protein 1-like 1 |
|
| chr21_-_43656125 Show fit | 1.05 |
ENSDART00000136392
ENSDART00000192805 ENSDART00000181960 |
si:ch211-263m18.4 si:dkey-229d11.5 |
|
| chr6_-_55297274 Show fit | 0.96 |
ENSDART00000184283
|
ubiquitin-conjugating enzyme E2C |
|
| chr9_-_2892045 Show fit | 0.95 |
ENSDART00000137201
|
cell division cycle associated 7a |
|
| chr15_-_17074393 Show fit | 0.90 |
ENSDART00000155526
|
si:ch211-24o10.6 |
|
| chr14_+_52563794 Show fit | 0.79 |
ENSDART00000168874
|
ribosomal protein L26 |
|
| chr9_-_2892250 Show fit | 0.78 |
ENSDART00000140695
|
cell division cycle associated 7a |
|
| chr7_+_1579510 Show fit | 0.77 |
ENSDART00000190525
|
SPT16 homolog, facilitates chromatin remodeling subunit |
|
| chr21_-_22681534 Show fit | 0.75 |
ENSDART00000159233
|
grass carp reovirus (GCRV)-induced gene 2f |
|
| chr11_-_24015845 Show fit | 0.70 |
ENSDART00000191783
|
chitinase, acidic.3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of mybl2b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.7 | GO:0048538 | thymus development(GO:0048538) |
| 0.2 | 1.1 | GO:1902315 | cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975) |
| 0.1 | 1.1 | GO:0034724 | DNA replication-independent nucleosome organization(GO:0034724) |
| 0.0 | 1.1 | GO:0001878 | response to yeast(GO:0001878) |
| 0.0 | 0.9 | GO:0006352 | DNA-templated transcription, initiation(GO:0006352) |
| 0.0 | 0.8 | GO:0006383 | transcription from RNA polymerase III promoter(GO:0006383) |
| 0.1 | 0.7 | GO:0006032 | chitin catabolic process(GO:0006032) |
| 0.0 | 0.7 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.1 | 0.6 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
| 0.1 | 0.6 | GO:0030326 | embryonic limb morphogenesis(GO:0030326) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.1 | GO:0035101 | FACT complex(GO:0035101) |
| 0.0 | 0.8 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 0.8 | GO:0045180 | basal cortex(GO:0045180) |
| 0.1 | 0.6 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.0 | 0.6 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.6 | GO:0005811 | lipid particle(GO:0005811) |
| 0.2 | 0.5 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.1 | 0.5 | GO:0000811 | GINS complex(GO:0000811) |
| 0.1 | 0.5 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.0 | 0.5 | GO:0035371 | microtubule plus-end(GO:0035371) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.0 | 0.8 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 0.7 | GO:0004568 | chitinase activity(GO:0004568) |
| 0.1 | 0.6 | GO:0051916 | granulocyte colony-stimulating factor binding(GO:0051916) |
| 0.1 | 0.6 | GO:0004478 | methionine adenosyltransferase activity(GO:0004478) |
| 0.1 | 0.6 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 0.1 | 0.6 | GO:0016728 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 0.1 | 0.6 | GO:0043142 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142) |
| 0.0 | 0.6 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.0 | 0.6 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 0.6 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 0.5 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 0.4 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.0 | 0.4 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.3 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.3 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.0 | 0.3 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.0 | 0.3 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.3 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.7 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 1.1 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.0 | 1.0 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.1 | 0.7 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 0.6 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 0.6 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.0 | 0.6 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 0.4 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.1 | 0.3 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 0.3 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |