ISMARA results: myb+mybl1

Project

PRJNA207719: Tissue specific transcriptome profiling

Navigation

Downloads

Results for myb+mybl1

Z-value: 1.81

Motif logo

Transcription factors associated with myb+mybl1

Gene Symbol	Gene ID	Gene Info
mybl1 NCBI UniProt	ENSDARG00000030999	v-myb avian myeloblastosis viral oncogene homolog-like 1
myb NCBI UniProt	ENSDARG00000053666	v-myb avian myeloblastosis viral oncogene homolog
myb NCBI UniProt	ENSDARG00000114024	v-myb avian myeloblastosis viral oncogene homolog

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
mybl1	dr11_v1_chr24_+_23791758_23791839	0.83	7.9e-02	Click!
myb	dr11_v1_chr23_+_31815423_31815492	-0.62	2.6e-01	Click!

Activity profile of myb+mybl1 motif

Sorted Z-values of myb+mybl1 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr11_-_101758 Show fit	2.01	ENSDART00000173015	elmo2 NCBI UniProt Show fit	engulfment and cell motility 2
chr3_+_19609638 Show fit	1.39	ENSDART00000079319	rprml NCBI UniProt Show fit	reprimo-like
chr3_-_12890670 Show fit	1.34	ENSDART00000159934 ENSDART00000188607	btbd17b NCBI UniProt Show fit	BTB (POZ) domain containing 17b
chr7_+_29148714 Show fit	1.23	ENSDART00000170342	mtbl NCBI UniProt Show fit	metallothionein-B-like
chr12_+_9880493 Show fit	1.19	ENSDART00000055019	ndufa4 NCBI UniProt Show fit	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4
chr10_-_7974155 Show fit	1.14	ENSDART00000147368 ENSDART00000075524	osbp2 NCBI UniProt Show fit	oxysterol binding protein 2
chr24_-_25574967 Show fit	1.11	ENSDART00000189828	cnksr2a NCBI UniProt Show fit	connector enhancer of kinase suppressor of Ras 2a
chr19_-_3240605 Show fit	1.06	ENSDART00000105168	si:ch211-133n4.4 NCBI UniProt Show fit	si:ch211-133n4.4
chr16_-_29458806 Show fit	1.05	ENSDART00000047931	lingo4b NCBI UniProt Show fit	leucine rich repeat and Ig domain containing 4b
chr9_-_41277347 Show fit	0.98	ENSDART00000181213	glsb NCBI UniProt Show fit	glutaminase b

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of myb+mybl1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.2	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1	1.8	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	1.5	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	1.5	GO:0097120	receptor localization to synapse(GO:0097120)
0.0	1.5	GO:0045732	positive regulation of protein catabolic process(GO:0045732)
0.0	1.3	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1	1.0	GO:0021534	cell proliferation in hindbrain(GO:0021534)
0.1	1.0	GO:0006537	glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0	1.0	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	1.0	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)

Showing 1 to 10 of 118 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.9	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	1.7	GO:0031225	anchored component of membrane(GO:0031225)
0.0	1.0	GO:0035371	microtubule plus-end(GO:0035371)
0.0	1.0	GO:0043204	perikaryon(GO:0043204)
0.1	0.9	GO:0031045	dense core granule(GO:0031045)
0.0	0.9	GO:0048788	cytoskeleton of presynaptic active zone(GO:0048788)
0.0	0.9	GO:0030426	growth cone(GO:0030426)
0.0	0.9	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.8	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.8	GO:0005891	voltage-gated calcium channel complex(GO:0005891)

Showing 1 to 10 of 53 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.0	GO:0017124	SH3 domain binding(GO:0017124)
0.0	1.3	GO:0045296	cadherin binding(GO:0045296)
0.1	1.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	1.1	GO:0015248	sterol transporter activity(GO:0015248)
0.2	1.0	GO:0016521	pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.1	1.0	GO:0004359	glutaminase activity(GO:0004359)
0.1	1.0	GO:0002039	p53 binding(GO:0002039)
0.0	1.0	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	1.0	GO:0051082	unfolded protein binding(GO:0051082)
0.0	0.9	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)

Showing 1 to 10 of 79 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.0	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	1.0	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.9	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.7	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.7	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	0.6	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.6	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.5	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.5	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Showing 1 to 10 of 20 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	1.2	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	1.0	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.7	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	0.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.5	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling

Showing 1 to 10 of 23 entries

Results for myb+mybl1

Z-value: 1.81

Motif logo

Transcription factors associated with myb+mybl1

Activity-expression correlation:

Activity profile of myb+mybl1 motif

Sorted Z-values of myb+mybl1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of myb+mybl1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: