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PRJNA207719: Tissue specific transcriptome profiling

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Results for msc

Z-value: 1.30

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Transcription factors associated with msc

Gene Symbol Gene ID Gene Info
ENSDARG00000110016 musculin (activated B-cell factor-1)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mscdr11_v1_chr24_+_13735616_137356160.128.5e-01Click!

Activity profile of msc motif

Sorted Z-values of msc motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_43952958 0.88 ENSDART00000039571
calcium/calmodulin-dependent protein kinase II alpha
chr6_+_13742899 0.83 ENSDART00000104722
cyclin-dependent kinase 5, regulatory subunit 2a (p39)
chr13_+_24834199 0.78 ENSDART00000101274
zgc:153981
chr20_-_27325258 0.70 ENSDART00000152917
ankyrin repeat and SOCS box containing 2a, tandem duplicate 1
chr13_+_42124566 0.69 ENSDART00000074707
CDC42 effector protein (Rho GTPase binding) 3
chr21_+_27382893 0.65 ENSDART00000005682
actinin alpha 3a
chr20_+_35382482 0.65 ENSDART00000135284
visinin-like 1a
chr5_-_38451082 0.64 ENSDART00000136428
cholinergic receptor, nicotinic, epsilon
chr14_-_32255126 0.64 ENSDART00000017259
fibroblast growth factor 13a
chr4_-_75175407 0.63 ENSDART00000180125

chr13_+_1575276 0.61 ENSDART00000165987
dystonin
chr11_-_1291012 0.61 ENSDART00000158390
ATPase plasma membrane Ca2+ transporting 2
chr21_+_11468642 0.60 ENSDART00000041869
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr1_+_25801648 0.59 ENSDART00000129471
guanylate cyclase 1 soluble subunit beta 1
chr7_+_7048245 0.57 ENSDART00000001649
actinin alpha 3b
chr15_-_32383529 0.57 ENSDART00000028349
complement component 4
chr15_+_40188076 0.56 ENSDART00000063779
EF-hand domain family, member D1
chr7_+_6969909 0.56 ENSDART00000189886
actinin alpha 3b
chr12_-_28570989 0.56 ENSDART00000008010
pyruvate dehydrogenase kinase, isozyme 2a
chr1_-_25911292 0.53 ENSDART00000145012
ubiquitin specific peptidase 53b
chr3_-_36115339 0.52 ENSDART00000187406
ENSDART00000123505
ENSDART00000151775
RAB11 family interacting protein 4 (class II) a
chr9_+_40939336 0.51 ENSDART00000100386
myostatin b
chr1_+_52560549 0.51 ENSDART00000167514
ATP-binding cassette, sub-family A (ABC1), member 1A
chr14_+_30730749 0.50 ENSDART00000087884
coiled-coil domain containing 85B
chr15_-_15357178 0.48 ENSDART00000106120
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2
chr7_+_27059330 0.47 ENSDART00000173919
pleckstrin homology domain containing, family A member 7b
chr5_-_51819027 0.47 ENSDART00000164267
homer scaffolding protein 1b
chr17_+_16873417 0.47 ENSDART00000146276
iodothyronine deiodinase 2
chr7_+_31879649 0.45 ENSDART00000099789
myosin binding protein C, cardiac
chr2_-_42128714 0.45 ENSDART00000047055
tripartite motif containing 55a
chr1_-_54997746 0.43 ENSDART00000152666
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23a
chr21_+_11468934 0.43 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr6_+_23887314 0.43 ENSDART00000163188
zinc finger protein 648
chr8_-_14151051 0.41 ENSDART00000090427
si:dkey-6n6.1
chr1_+_2101541 0.41 ENSDART00000128187
ENSDART00000167050
ENSDART00000182153
ENSDART00000122626
ENSDART00000164488
muscleblind-like splicing regulator 2
chr7_+_31879986 0.41 ENSDART00000138491
myosin binding protein C, cardiac
chr15_-_32383340 0.41 ENSDART00000185632
complement component 4
chr4_-_9586713 0.41 ENSDART00000145613
SH3 and multiple ankyrin repeat domains 3b
chr5_-_31904562 0.41 ENSDART00000140640
coronin, actin binding protein, 1Cb
chr21_-_16632808 0.40 ENSDART00000172645
unc-5 netrin receptor Da
chr19_-_9711472 0.39 ENSDART00000016197
ENSDART00000175075
solute carrier family 2 (facilitated glucose transporter), member 3a
chr10_+_34315719 0.39 ENSDART00000135303
StAR-related lipid transfer (START) domain containing 13a
chr18_+_25003207 0.38 ENSDART00000099476
ENSDART00000132285
family with sequence similarity 174, member B
chr19_+_1184878 0.37 ENSDART00000163539
scratch family zinc finger 1a
chr14_+_21783229 0.37 ENSDART00000170784
ankyrin repeat domain 13 family, member D
chr14_+_7939398 0.37 ENSDART00000189773
CXXC finger protein 5b
chr1_+_33401774 0.37 ENSDART00000149786
ENSDART00000110026
ENSDART00000148946
dehydrogenase/reductase (SDR family) X-linked
chr19_-_10425140 0.37 ENSDART00000145319
si:ch211-171h4.3
chr23_-_18057553 0.36 ENSDART00000173102
ENSDART00000058742
zgc:92287
chr7_-_23745984 0.36 ENSDART00000048050
zgc:92429
chr2_+_45696743 0.36 ENSDART00000114225
ENSDART00000169279

chr10_+_15777258 0.35 ENSDART00000140511
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr21_-_20929575 0.35 ENSDART00000163889
complement component 6
chr14_+_5936996 0.35 ENSDART00000097144
ENSDART00000126777
potassium channel tetramerization domain containing 8
chr9_+_52492639 0.35 ENSDART00000078939
membrane-associated ring finger (C3HC4) 4
chr17_-_14726824 0.35 ENSDART00000162947
si:ch73-305o9.3
chr2_-_44255537 0.34 ENSDART00000011188
ENSDART00000093298
ATPase Na+/K+ transporting subunit alpha 2
chr13_-_31452516 0.34 ENSDART00000193268
reticulon 1a
chr1_-_20593778 0.34 ENSDART00000124770
UDP glycosyltransferase 8
chr14_+_7939216 0.34 ENSDART00000171657
CXXC finger protein 5b
chr10_-_34741738 0.34 ENSDART00000163072
doublecortin-like kinase 1a
chr8_-_44004135 0.34 ENSDART00000136269
RIMS binding protein 2
chr7_+_26224211 0.33 ENSDART00000173999
VGF nerve growth factor inducible
chr5_+_3501859 0.33 ENSDART00000080486
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr13_-_12581388 0.33 ENSDART00000079655
glutamyl aminopeptidase
chr14_+_21783400 0.33 ENSDART00000164023
ankyrin repeat domain 13 family, member D
chr5_+_42097608 0.32 ENSDART00000014404
purinergic receptor P2X, ligand-gated ion channel, 5
chr16_+_3004422 0.31 ENSDART00000189969

chr10_+_15777064 0.31 ENSDART00000114483
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr5_-_22019061 0.31 ENSDART00000113066
APC membrane recruitment protein 1
chr2_+_37480669 0.31 ENSDART00000029801
signal peptide peptidase-like 2
chr6_-_40098641 0.30 ENSDART00000017402
inositol hexakisphosphate kinase 2b
chr9_-_98982 0.30 ENSDART00000147882
LIM and senescent cell antigen-like domains 2
chr20_+_23501535 0.29 ENSDART00000177922
ENSDART00000058532
palladin, cytoskeletal associated protein
chr7_+_19552381 0.29 ENSDART00000169060
si:ch211-212k18.5
chr5_-_30475011 0.28 ENSDART00000187501
pleckstrin homology-like domain, family B, member 1a
chr21_-_27123139 0.28 ENSDART00000077478
solute carrier family 8 (sodium/calcium exchanger), member 4a
chr24_+_38155830 0.28 ENSDART00000152019
si:ch211-234p6.5
chr18_+_39028417 0.28 ENSDART00000148428
myosin VAa
chr2_-_30659222 0.27 ENSDART00000145405
catenin (cadherin-associated protein), delta 2b
chr11_+_24314148 0.27 ENSDART00000171491
RAS (RAD and GEM)-like GTP-binding 1
chr6_+_39222598 0.27 ENSDART00000154991
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr8_+_25247245 0.27 ENSDART00000045798
adenosine monophosphate deaminase 2b
chr6_+_27339962 0.27 ENSDART00000193726
kelch-like family member 30
chr13_-_40499296 0.27 ENSDART00000158338
Danio rerio cyclin and CBS domain divalent metal cation transport mediator 1 (cnnm1), mRNA.
chr5_-_40734045 0.27 ENSDART00000010896
ISL LIM homeobox 1
chr4_+_12615836 0.27 ENSDART00000003583
LIM domain only 3
chr23_-_30954738 0.27 ENSDART00000188996
oxysterol binding protein-like 2a
chr13_-_31164749 0.27 ENSDART00000049180
mitogen-activated protein kinase 8a
chr23_-_24263474 0.26 ENSDART00000160312
heat shock protein family, member 7 (cardiovascular)
chr11_+_24313931 0.26 ENSDART00000017599
ENSDART00000166045
RAS (RAD and GEM)-like GTP-binding 1
chr20_-_26467307 0.26 ENSDART00000078072
ENSDART00000158213
A kinase (PRKA) anchor protein 12b
chr12_+_5209822 0.26 ENSDART00000152610
si:ch211-197g18.2
chr6_+_40587551 0.25 ENSDART00000155554
fibroblast growth factor receptor substrate 3
chr12_+_33038757 0.25 ENSDART00000153146
RNA binding fox-1 homolog 3a
chr6_-_16667886 0.25 ENSDART00000180854
ENSDART00000190116
unc-80 homolog (C. elegans)
chr4_+_12617108 0.25 ENSDART00000134362
ENSDART00000112860
LIM domain only 3
chr23_-_8373676 0.25 ENSDART00000105135
ENSDART00000158531
opiate receptor-like 1
chr14_+_26805388 0.25 ENSDART00000044389
ENSDART00000173126
kelch-like family member 4
chr2_-_32551178 0.25 ENSDART00000145603
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr23_-_32162810 0.25 ENSDART00000155905
nuclear receptor subfamily 4, group A, member 1
chr8_-_43997538 0.25 ENSDART00000186449
RIMS binding protein 2
chr5_-_10768258 0.24 ENSDART00000157043
reticulon 4 receptor
chr23_+_35714574 0.24 ENSDART00000164616
tubulin, alpha 1c
chr12_+_17504559 0.24 ENSDART00000020628
cytohesin 3a
chr1_-_17650223 0.24 ENSDART00000043484
si:dkey-256e7.5
chr9_+_23665777 0.24 ENSDART00000060905
glycophorin C (Gerbich blood group)
chr21_-_3770636 0.24 ENSDART00000053596
secretory carrier membrane protein 1
chr24_+_33802528 0.24 ENSDART00000136040
ENSDART00000147499
ENSDART00000182322
autophagy related 9B
chr14_-_16754262 0.24 ENSDART00000001159
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr1_-_29747702 0.24 ENSDART00000133225
ENSDART00000189670
secreted phosphoprotein 2
chr7_+_27277236 0.24 ENSDART00000185161
SRY (sex determining region Y)-box 6
chr19_-_10432134 0.24 ENSDART00000081440
interleukin 11b
chr21_-_17482465 0.23 ENSDART00000004548
BarH-like homeobox 1b
chr25_+_36674715 0.23 ENSDART00000111861
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog b (paralog b)
chr4_+_20255160 0.23 ENSDART00000188658
leucine-rich repeats and transmembrane domains 2a
chr17_-_14836320 0.23 ENSDART00000157051
nidogen 2a (osteonidogen)
chr9_-_28939181 0.23 ENSDART00000101276
ENSDART00000135334
erythrocyte membrane protein band 4.1 like 5
chr6_+_2097690 0.23 ENSDART00000193770
transglutaminase 2b
chr18_-_5781922 0.23 ENSDART00000128722
si:ch73-167i17.6
chr14_-_15699528 0.23 ENSDART00000161123
neuralized E3 ubiquitin protein ligase 1B
chr18_-_399554 0.23 ENSDART00000164374
ENSDART00000186311
ENSDART00000181816
ENSDART00000181892
si:ch211-79l17.1
chr3_+_29714775 0.22 ENSDART00000041388
calcium channel, voltage-dependent, gamma subunit 2a
chr21_-_24865217 0.22 ENSDART00000101136
immunoglobulin superfamily, member 9Bb
chr7_+_63325819 0.22 ENSDART00000085612
ENSDART00000161436
protocadherin 7b
chr14_-_46832825 0.22 ENSDART00000149571
LIM domain binding 2a
chr8_-_11229523 0.22 ENSDART00000002164
unc-45 myosin chaperone B
chr24_+_24461558 0.22 ENSDART00000182424
basic helix-loop-helix family, member e22
chr19_-_10214264 0.22 ENSDART00000053300
ENSDART00000148225
zinc finger protein 865
chr6_-_12722360 0.22 ENSDART00000090174
dedicator of cytokinesis 9b
chr25_+_36045072 0.22 ENSDART00000126326
RPGRIP1-like
chr15_+_9327252 0.22 ENSDART00000144381
sarcoglycan, gamma
chr22_-_18179214 0.22 ENSDART00000129576
si:ch211-125m10.6
chr4_-_23858900 0.21 ENSDART00000123199
USP6 N-terminal like
chr8_-_24965308 0.21 ENSDART00000087293
ENSDART00000146805
potassium voltage-gated channel, Shaw-related subfamily, member 4
chr10_+_24468922 0.21 ENSDART00000008248
ENSDART00000183510
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr13_+_2894536 0.21 ENSDART00000183678

chr10_-_24371312 0.21 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr19_-_33087246 0.21 ENSDART00000052078
kelch-like family member 38a
chr16_+_11151699 0.21 ENSDART00000140674
capicua transcriptional repressor b
chr10_-_25069155 0.21 ENSDART00000078226
ENSDART00000181941
melatonin receptor 1Bb
chr20_+_46560258 0.21 ENSDART00000122115
si:ch211-153j24.3
chr4_+_20263097 0.21 ENSDART00000138820
leucine-rich repeats and transmembrane domains 2a
chr6_+_29217392 0.20 ENSDART00000006386
ATPase Na+/K+ transporting subunit beta 1a
chr8_+_50727220 0.20 ENSDART00000127062
early growth response 3
chr3_+_22935183 0.20 ENSDART00000157378
histone deacetylase 5
chr19_+_42770041 0.20 ENSDART00000150930
cytoplasmic linker associated protein 2
chr19_+_7001170 0.20 ENSDART00000110366
zinc finger and BTB domain containing 22b
chr7_+_6652967 0.19 ENSDART00000102681
purine nucleoside phosphorylase 5a
chr21_-_24865454 0.19 ENSDART00000142907
immunoglobulin superfamily, member 9Bb
chr6_-_8865217 0.19 ENSDART00000151443
transmembrane protein with EGF-like and two follistatin-like domains 2b
chr16_-_42750295 0.19 ENSDART00000176570
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr18_+_19820008 0.19 ENSDART00000079691
ENSDART00000135049
IQ motif containing H
chr8_+_48484455 0.19 ENSDART00000122737
si:ch211-263k4.2
chr17_+_8292892 0.18 ENSDART00000125728
si:ch211-236p5.3
chr15_+_33989181 0.18 ENSDART00000169487
von Willebrand factor D and EGF domains
chr20_-_42439896 0.18 ENSDART00000061049
vestigial-like family member 2a
chr19_-_32888758 0.18 ENSDART00000052080
lysosomal protein transmembrane 4 beta
chr3_-_23596532 0.18 ENSDART00000124921
ubiquitin-conjugating enzyme E2Z
chr3_+_20156956 0.17 ENSDART00000125281
nerve growth factor receptor a (TNFR superfamily, member 16)
chr3_+_36515376 0.17 ENSDART00000161652
si:dkeyp-72e1.9
chr20_-_18915376 0.17 ENSDART00000063725
XK, Kell blood group complex subunit-related family, member 6b
chr4_+_12113105 0.17 ENSDART00000182399
transmembrane protein 178B
chr11_-_17713987 0.17 ENSDART00000090401
family with sequence similarity 19 (chemokine (C-C motif)-like), member A4b
chr13_+_43400443 0.17 ENSDART00000084321
dishevelled-binding antagonist of beta-catenin 2
chr5_+_34622320 0.17 ENSDART00000141338
ectodermal-neural cortex 1
chr9_-_8454060 0.17 ENSDART00000110158
insulin receptor substrate 2b
chr4_-_18635005 0.17 ENSDART00000125361
peroxisome proliferator-activated receptor alpha a
chr7_+_27253063 0.17 ENSDART00000191138
SRY (sex determining region Y)-box 6
chr7_+_24251367 0.17 ENSDART00000173642
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr4_-_20081621 0.16 ENSDART00000024647
DENN/MADD domain containing 6B
chr6_-_35032792 0.16 ENSDART00000168256
discoidin domain receptor tyrosine kinase 2a
chr23_-_26880623 0.16 ENSDART00000038491
adenylate cyclase 6b
chr23_+_13528550 0.16 ENSDART00000099903
uridine-cytidine kinase 1-like 1b
chr22_+_16308450 0.16 ENSDART00000105678
leucine rich repeat containing 39
chr6_-_8865543 0.16 ENSDART00000042115
transmembrane protein with EGF-like and two follistatin-like domains 2b
chr15_-_29387446 0.16 ENSDART00000145976
ENSDART00000035096
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr24_+_26276805 0.16 ENSDART00000089749
adiponectin, C1Q and collagen domain containing, a
chr19_+_44039849 0.16 ENSDART00000086040
leucine rich repeat containing 14B
chr3_-_23596809 0.16 ENSDART00000156897
ubiquitin-conjugating enzyme E2Z
chr3_-_28075756 0.16 ENSDART00000122037
RNA binding fox-1 homolog 1
chr6_+_4872883 0.16 ENSDART00000186730
ENSDART00000092290
ENSDART00000151674
protocadherin 9
chr9_+_38168012 0.15 ENSDART00000102445
cytoplasmic linker associated protein 1a
chr4_-_17823424 0.15 ENSDART00000024822
DnaJ (Hsp40) homolog, subfamily B, member 9b
chr20_-_18731268 0.15 ENSDART00000183893
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr5_-_60159116 0.15 ENSDART00000147675
si:dkey-280e8.1
chr25_-_19655820 0.15 ENSDART00000149585
ENSDART00000104353
ATPase plasma membrane Ca2+ transporting 1b
chr25_-_35542739 0.15 ENSDART00000097651
si:ch211-87j1.4
chr17_+_12075805 0.15 ENSDART00000155329
consortin, connexin sorting protein a
chr1_-_17587552 0.15 ENSDART00000039917
acyl-CoA synthetase long chain family member 1a
chr11_-_36963988 0.14 ENSDART00000168288
calcium channel, voltage-dependent, L type, alpha 1D subunit, a
chr13_+_18545819 0.14 ENSDART00000101859
ENSDART00000110197
ENSDART00000136064
zgc:154058
chr8_+_36948256 0.14 ENSDART00000140410
IQ motif and Sec7 domain 2b
chr18_-_7948188 0.14 ENSDART00000091805
SH3 and multiple ankyrin repeat domains 3a
chr14_-_9355177 0.13 ENSDART00000138535
family with sequence similarity 46, member D
chr7_-_48263516 0.13 ENSDART00000006619
ENSDART00000142370
ENSDART00000148273
ENSDART00000147968
RNA binding protein with multiple splicing 2b
chr21_-_38618540 0.13 ENSDART00000036600
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr7_+_20471315 0.13 ENSDART00000173714
si:dkey-19b23.13
chr8_+_7033049 0.13 ENSDART00000064172
ENSDART00000134440
glycerol-3-phosphate dehydrogenase 1a
chr2_+_4208323 0.13 ENSDART00000167906
GATA binding protein 6

Network of associatons between targets according to the STRING database.

First level regulatory network of msc

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.6 GO:0099548 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 0.5 GO:0045843 negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.1 0.5 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.1 0.3 GO:0065001 specification of axis polarity(GO:0065001)
0.1 0.5 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.3 GO:1904969 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.1 0.5 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 1.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.7 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.1 GO:0051148 negative regulation of muscle cell differentiation(GO:0051148)
0.1 0.5 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.1 0.4 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.2 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.4 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.5 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:1903373 regulation of endoplasmic reticulum tubular network organization(GO:1903371) positive regulation of endoplasmic reticulum tubular network organization(GO:1903373)
0.0 0.1 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.3 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.0 0.4 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.6 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.1 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0098773 skin epidermis development(GO:0098773)
0.0 0.2 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.0 0.2 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0033198 response to ATP(GO:0033198)
0.0 0.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.1 GO:0015709 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.3 GO:0042044 fluid transport(GO:0042044)
0.0 0.1 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.0 0.1 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.8 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.5 GO:0001843 neural tube closure(GO:0001843)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.2 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.1 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.0 0.2 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.1 GO:0045687 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.1 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.9 GO:0003146 heart jogging(GO:0003146)
0.0 0.1 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.0 0.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0006211 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.0 GO:0090278 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.0 0.1 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.0 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.4 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.2 GO:0046849 bone remodeling(GO:0046849)
0.0 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.0 GO:0060300 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.0 0.6 GO:0010906 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.0 0.0 GO:0010226 response to lithium ion(GO:0010226)
0.0 0.3 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.3 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0018149 peptide cross-linking(GO:0018149)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.3 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0098826 endoplasmic reticulum tubular network membrane(GO:0098826)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.1 GO:0097519 DNA recombinase complex(GO:0097519)
0.0 0.4 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.8 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.6 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.2 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.6 GO:0030426 growth cone(GO:0030426)
0.0 0.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.9 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.4 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 1.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.7 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.4 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.1 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.0 0.2 GO:0005035 death receptor activity(GO:0005035)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.0 0.0 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.0 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 0.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade