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PRJNA207719: Tissue specific transcriptome profiling
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Results for meox2b
Z-value: 1.55
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Transcription factors associated with meox2b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| meox2b | dr11_v1_chr19_+_31183495_31183495 | -0.33 | 5.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr21_+_25777425 Show fit | 1.62 |
ENSDART00000021620
|
claudin d |
|
| chr10_+_21867307 Show fit | 1.44 |
ENSDART00000126629
|
cerebellin 17 |
|
| chr22_+_1170294 Show fit | 1.29 |
ENSDART00000159761
ENSDART00000169809 |
interferon regulatory factor 6 |
|
| chr12_+_31713239 Show fit | 1.21 |
ENSDART00000122379
|
hyaluronan binding protein 2 |
|
| chr21_+_27416284 Show fit | 1.13 |
ENSDART00000077593
ENSDART00000108763 |
complement factor B |
|
| chr10_-_8046764 Show fit | 1.09 |
ENSDART00000099031
|
zgc:136254 |
|
| chr6_+_41191482 Show fit | 1.07 |
ENSDART00000000877
|
opsin 1 (cone pigments), medium-wave-sensitive, 3 |
|
| chr20_-_40755614 Show fit | 1.05 |
ENSDART00000061247
|
connexin 32.3 |
|
| chr4_-_2380173 Show fit | 1.05 |
ENSDART00000177727
|
nucleosome assembly protein 1-like 1 |
|
| chr15_-_21877726 Show fit | 1.03 |
ENSDART00000127819
ENSDART00000145646 ENSDART00000100897 ENSDART00000144739 |
zgc:162608 |
Network of associatons between targets according to the STRING database.
First level regulatory network of meox2b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.0 | GO:0032355 | response to estradiol(GO:0032355) |
| 0.1 | 1.9 | GO:0048702 | embryonic neurocranium morphogenesis(GO:0048702) |
| 0.0 | 1.7 | GO:0007596 | blood coagulation(GO:0007596) |
| 0.3 | 1.6 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.2 | 1.4 | GO:0001659 | temperature homeostasis(GO:0001659) |
| 0.0 | 1.3 | GO:0001878 | response to yeast(GO:0001878) |
| 0.0 | 1.3 | GO:1902036 | regulation of hematopoietic stem cell differentiation(GO:1902036) |
| 0.4 | 1.1 | GO:0060631 | regulation of meiosis I(GO:0060631) |
| 0.0 | 1.1 | GO:0007602 | phototransduction(GO:0007602) |
| 0.0 | 1.1 | GO:0072376 | complement activation(GO:0006956) protein activation cascade(GO:0072376) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.5 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.1 | 4.2 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 2.0 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.1 | 1.6 | GO:0042627 | chylomicron(GO:0042627) |
| 0.0 | 1.3 | GO:0005840 | ribosome(GO:0005840) |
| 0.0 | 1.2 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 1.1 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 1.1 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.1 | 1.0 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 1.0 | GO:0043186 | P granule(GO:0043186) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.1 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 4.6 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 3.4 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.3 | 1.6 | GO:0009374 | biotin binding(GO:0009374) |
| 0.2 | 1.5 | GO:0045735 | nutrient reservoir activity(GO:0045735) |
| 0.0 | 1.5 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 1.3 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.0 | 1.2 | GO:0003724 | RNA helicase activity(GO:0003724) |
| 0.0 | 1.1 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.0 | 1.1 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 2.8 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 1.7 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.1 | 1.1 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 1.0 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.8 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.0 | 0.7 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 0.7 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.0 | 0.6 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 0.6 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.9 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.1 | 1.3 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 1.3 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.3 | 1.1 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.1 | 1.0 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.2 | 0.9 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.0 | 0.9 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 0.9 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.0 | 0.9 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 0.8 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |