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PRJNA207719: Tissue specific transcriptome profiling

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Results for meox2b

Z-value: 1.55

Motif logo

Transcription factors associated with meox2b

Gene Symbol Gene ID Gene Info
ENSDARG00000061818 mesenchyme homeobox 2b
ENSDARG00000116206 mesenchyme homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
meox2bdr11_v1_chr19_+_31183495_31183495-0.335.8e-01Click!

Activity profile of meox2b motif

Sorted Z-values of meox2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_25777425 1.62 ENSDART00000021620
claudin d
chr10_+_21867307 1.44 ENSDART00000126629
cerebellin 17
chr22_+_1170294 1.29 ENSDART00000159761
ENSDART00000169809
interferon regulatory factor 6
chr12_+_31713239 1.21 ENSDART00000122379
hyaluronan binding protein 2
chr21_+_27416284 1.13 ENSDART00000077593
ENSDART00000108763
complement factor B
chr10_-_8046764 1.09 ENSDART00000099031
zgc:136254
chr6_+_41191482 1.07 ENSDART00000000877
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr20_-_40755614 1.05 ENSDART00000061247
connexin 32.3
chr4_-_2380173 1.05 ENSDART00000177727
nucleosome assembly protein 1-like 1
chr15_-_21877726 1.03 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
chr6_-_27123327 0.98 ENSDART00000073881
alanine-glyoxylate aminotransferase a
chr16_-_29387215 0.95 ENSDART00000148787
S100 calcium binding protein A1
chr10_-_8053753 0.93 ENSDART00000162289
si:ch211-251f6.7
chr8_-_10932206 0.93 ENSDART00000124313
nuclear receptor subfamily 1, group H, member 5
chr12_-_22524388 0.92 ENSDART00000020942
sex hormone-binding globulin
chr16_+_23913943 0.92 ENSDART00000175404
ENSDART00000129525
apolipoprotein A-IV b, tandem duplicate 1
chr16_-_54455573 0.89 ENSDART00000075275
pyruvate kinase L/R
chr11_-_37997419 0.89 ENSDART00000102870
solute carrier family 41 (magnesium transporter), member 1
chr1_-_18811517 0.87 ENSDART00000142026
si:dkey-167i21.2
chr10_-_21362071 0.87 ENSDART00000125167
avidin
chr22_-_24738188 0.86 ENSDART00000050238
vitellogenin 1
chr11_-_1550709 0.86 ENSDART00000110097
si:ch73-303b9.1
chr15_+_46357080 0.85 ENSDART00000155571
ENSDART00000156541
wu:fb18f06
chr5_-_25723079 0.85 ENSDART00000014013
guanine deaminase
chr16_-_2414063 0.84 ENSDART00000073621
zgc:152945
chr23_-_31913231 0.83 ENSDART00000146852
ENSDART00000085054
mitochondrial fission regulator 2
chr3_+_13624815 0.81 ENSDART00000161451
peptidoglycan recognition protein 6
chr1_-_43905252 0.80 ENSDART00000135477
ENSDART00000132089
si:dkey-22i16.3
chr9_-_2892045 0.79 ENSDART00000137201
cell division cycle associated 7a
chr15_+_36457888 0.78 ENSDART00000155100
si:dkey-262k9.2
chr20_-_23426339 0.78 ENSDART00000004625
zygote arrest 1
chr2_+_41926707 0.77 ENSDART00000023208
zgc:110183
chr12_+_20352400 0.76 ENSDART00000066383
hemoglobin, alpha embryonic 5
chr20_+_2281933 0.75 ENSDART00000137579
si:ch73-18b11.2
chr22_+_12770877 0.75 ENSDART00000044683
formimidoyltransferase cyclodeaminase
chr10_-_44560165 0.74 ENSDART00000181217
ENSDART00000076084
nucleophosmin/nucleoplasmin, 2b
chr10_-_21362320 0.73 ENSDART00000189789
avidin
chr7_+_69019851 0.72 ENSDART00000162891

chr18_+_20560616 0.70 ENSDART00000136710
ENSDART00000151974
ENSDART00000121699
ENSDART00000040074
WEE1 homolog 2 (S. pombe)
chr15_+_46356879 0.70 ENSDART00000154388
wu:fb18f06
chr3_+_18398876 0.70 ENSDART00000141100
ENSDART00000138107
ribosomal protein S2
chr22_-_15578402 0.68 ENSDART00000062986
hematopoietic SH2 domain containing
chr9_-_2892250 0.68 ENSDART00000140695
cell division cycle associated 7a
chr24_-_38110779 0.68 ENSDART00000147783
c-reactive protein, pentraxin-related
chr2_-_26596794 0.67 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr20_-_6532462 0.67 ENSDART00000054653
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like
chr1_-_45049603 0.67 ENSDART00000023336
ribosomal protein S6
chr15_+_45563656 0.66 ENSDART00000157501
claudin 15-like b
chr18_+_15644559 0.65 ENSDART00000061794
nuclear receptor subfamily 1, group H, member 4
chr22_-_24818066 0.65 ENSDART00000143443
vitellogenin 6
chr8_+_21353878 0.65 ENSDART00000056420
aminolevulinate, delta-, synthase 2
chr25_+_3327071 0.64 ENSDART00000136131
ENSDART00000133243
lactate dehydrogenase Bb
chr25_+_10410620 0.63 ENSDART00000151886
ets homologous factor
chr16_-_45178430 0.63 ENSDART00000165186
si:dkey-33i11.9
chr16_+_29509133 0.61 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr3_+_1015867 0.61 ENSDART00000109912
si:ch1073-464p5.5
chr13_-_20381485 0.60 ENSDART00000131351
si:ch211-270n8.1
chr16_+_33902006 0.60 ENSDART00000161807
ENSDART00000159474
guanine nucleotide binding protein-like 2 (nucleolar)
chr13_+_23988442 0.59 ENSDART00000010918
angiotensinogen
chr19_-_18313303 0.59 ENSDART00000164644
ENSDART00000167480
ENSDART00000163104
si:dkey-208k4.2
chr11_-_35171768 0.59 ENSDART00000192896
TRAF-interacting protein
chr14_+_17376940 0.58 ENSDART00000054590
ENSDART00000010148
spondin 2b, extracellular matrix protein
chr6_-_43283122 0.58 ENSDART00000186022
FERM domain containing 4Ba
chr8_+_6576940 0.58 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr8_-_23780334 0.57 ENSDART00000145179
ENSDART00000145894
zgc:195245
chr6_+_52873822 0.57 ENSDART00000103138
odorant receptor, family H, subfamily 137, member 3
chr16_+_23984179 0.56 ENSDART00000175879
apolipoprotein C-II
chr10_-_25217347 0.55 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr14_-_21064199 0.55 ENSDART00000172099
si:dkey-74k8.3
chr1_-_999556 0.54 ENSDART00000170884
ENSDART00000172235
phosphoribosylglycinamide formyltransferase
chr18_-_20674121 0.54 ENSDART00000005145
ankyrin repeat, SAM and basic leucine zipper domain containing 1
chr2_+_37227011 0.54 ENSDART00000126587
ENSDART00000084958
sterile alpha motif domain containing 7
chr10_-_8060573 0.54 ENSDART00000147104
ENSDART00000099030
si:ch211-251f6.6
chr22_+_7439186 0.53 ENSDART00000190667
zgc:92041
chr7_+_21841037 0.53 ENSDART00000077503
transmembrane 4 L six family member 5
chr5_+_26213874 0.53 ENSDART00000193816
ENSDART00000098514
occludin b
chr11_-_2478374 0.53 ENSDART00000173205
si:ch73-267c23.10
chr4_-_13502549 0.53 ENSDART00000140366
si:ch211-266a5.12
chr17_-_30635298 0.52 ENSDART00000155478
SH3 and SYLF domain containing 1
chr12_-_35830625 0.51 ENSDART00000180028

chr10_-_8079737 0.51 ENSDART00000059014
ENSDART00000179549
zgc:173443
si:ch211-251f6.6
chr7_-_12968689 0.51 ENSDART00000173115
ENSDART00000013690
ribosomal protein, large P2, like
chr1_-_58562129 0.51 ENSDART00000159070
solute carrier family 27 (fatty acid transporter), member 1b
chr22_-_13649588 0.51 ENSDART00000131877
si:ch211-279g13.1
chr4_+_14981854 0.51 ENSDART00000067046
cation/H+ exchanger protein 1
chr10_-_3295197 0.51 ENSDART00000109131
slc25a1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1b
chr15_+_31344472 0.50 ENSDART00000146695
ENSDART00000159182
ENSDART00000060125
odorant receptor, family D, subfamily 107, member 1
chr1_-_58561963 0.50 ENSDART00000165040
solute carrier family 27 (fatty acid transporter), member 1b
chr8_+_45334255 0.50 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
poly(A) binding protein, cytoplasmic 1-like
chr7_+_2236317 0.50 ENSDART00000075859
zgc:172065
chr2_-_5475910 0.50 ENSDART00000100954
ENSDART00000172143
ENSDART00000132496
protein C (inactivator of coagulation factors Va and VIIIa), a
protein C (inactivator of coagulation factors Va and VIIIa), a
chr10_+_6884627 0.50 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr20_-_49704915 0.50 ENSDART00000189232
cytochrome c oxidase subunit 7A2
chr21_+_19062124 0.50 ENSDART00000134746
ribosomal protein L17
chr3_-_16719244 0.49 ENSDART00000055859
polymerase (DNA directed), delta 1, catalytic subunit
chr10_-_35257458 0.49 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr21_-_5205617 0.49 ENSDART00000145554
ENSDART00000045284
ribosomal protein L37
chr21_+_20903244 0.49 ENSDART00000186193
complement component 7b
chr11_+_1602916 0.49 ENSDART00000184434
ENSDART00000112597
ENSDART00000192165
si:dkey-40c23.2
si:dkey-40c23.3
chr10_-_21955231 0.49 ENSDART00000183695

chr10_-_8053385 0.49 ENSDART00000142714
si:ch211-251f6.7
chr1_+_21563311 0.49 ENSDART00000147076
ENSDART00000006147
primase and polymerase (DNA-directed)
chr3_-_19517462 0.49 ENSDART00000162027

chr11_-_6452444 0.49 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
La ribonucleoprotein domain family, member 6b
chr8_+_14886452 0.48 ENSDART00000146589
sterol O-acyltransferase 1
chr16_+_42471455 0.48 ENSDART00000166640
si:ch211-215k15.5
chr25_+_5972690 0.47 ENSDART00000067517
si:ch211-11i22.4
chr24_-_37640705 0.47 ENSDART00000066583
zgc:112496
chr2_-_10703621 0.47 ENSDART00000005944
ribosomal protein L5a
chr21_+_43702016 0.47 ENSDART00000017176
dyskeratosis congenita 1, dyskerin
chr4_+_391297 0.47 ENSDART00000030215
ribosomal protein L18a
chr6_+_8630355 0.47 ENSDART00000161749
ENSDART00000193976
thrombospondin-type laminin G domain and EAR repeats a
chr18_-_19456269 0.46 ENSDART00000060363
ribosomal protein L4
chr12_+_22580579 0.46 ENSDART00000171725
ENSDART00000192290
capping protein (actin filament), gelsolin-like b
chr15_-_44052927 0.46 ENSDART00000166209
wu:fb44b02
chr8_-_31107537 0.46 ENSDART00000098925
vestigial like 4 like
chr4_-_77125693 0.46 ENSDART00000174256

chr19_-_11238620 0.45 ENSDART00000148697
ENSDART00000149169
signal sequence receptor, beta
chr16_-_42056137 0.44 ENSDART00000102798
zona pellucida glycoprotein 3d tandem duplicate 2
chr6_-_39649504 0.44 ENSDART00000179960
ENSDART00000190951
La ribonucleoprotein domain family, member 4Ab
chr1_-_45146834 0.44 ENSDART00000144997
si:ch211-239f4.6
chr19_-_11237125 0.44 ENSDART00000163921
signal sequence receptor, beta
chr19_+_15440841 0.43 ENSDART00000182329
lin-28 homolog A (C. elegans)
chr3_-_19561058 0.43 ENSDART00000079323
zgc:163079
chr12_-_5728755 0.43 ENSDART00000105887
distal-less homeobox 4b
chr1_+_53374454 0.43 ENSDART00000038807
uncoupling protein 1
chr14_-_15171435 0.43 ENSDART00000159148
ENSDART00000166622
si:dkey-77g12.1
chr12_+_46404307 0.43 ENSDART00000185011

chr2_-_36490570 0.43 ENSDART00000109828

chr22_+_25753972 0.42 ENSDART00000188417

chr23_+_11285662 0.42 ENSDART00000111028
cell adhesion molecule L1-like a
chr1_-_9195629 0.42 ENSDART00000143587
ENSDART00000192174
endoplasmic reticulum to nucleus signaling 2
chr17_+_20174812 0.42 ENSDART00000186628
si:ch211-248a14.8
chr3_+_17537352 0.42 ENSDART00000104549
hypocretin (orexin) neuropeptide precursor
chr3_+_32129632 0.41 ENSDART00000174522
zgc:109934
chr8_+_45338073 0.41 ENSDART00000185024
poly(A) binding protein, cytoplasmic 1-like
chr24_+_16985181 0.41 ENSDART00000135580
eukaryotic translation initiation factor 2, subunit 3 gamma
chr9_-_18911608 0.41 ENSDART00000138785
si:dkey-239h2.3
chr1_+_45056371 0.41 ENSDART00000073689
ENSDART00000167309
bloodthirsty-related gene family, member 1
chr2_-_15324837 0.41 ENSDART00000015655
trans-2,3-enoyl-CoA reductase-like 2b
chr24_-_11076400 0.41 ENSDART00000003195
charged multivesicular body protein 4C
chr21_-_7035599 0.40 ENSDART00000139777
si:ch211-93g21.1
chr13_+_28747934 0.40 ENSDART00000160176
ENSDART00000101633
ENSDART00000136318
prominin 2
chr1_-_55248496 0.40 ENSDART00000098615
nanos homolog 3
chr13_+_33688474 0.40 ENSDART00000161465

chr25_+_29474982 0.40 ENSDART00000130410
interleukin 17 receptor E-like
chr19_-_42571829 0.40 ENSDART00000102606
zgc:103438
chr23_+_36095260 0.40 ENSDART00000127384
homeobox C9a
chr13_-_31017960 0.40 ENSDART00000145287
WDFY family member 4
chr19_+_15441022 0.39 ENSDART00000098970
ENSDART00000140276
lin-28 homolog A (C. elegans)
chr5_+_6954162 0.39 ENSDART00000086666
sperm-tail PG-rich repeat containing 2
chr4_-_13548806 0.39 ENSDART00000067155
interleukin 22
chr5_-_33287691 0.39 ENSDART00000004238
ribosomal protein L7a
chr18_+_14564085 0.38 ENSDART00000009363
ENSDART00000141813
ENSDART00000136120
si:dkey-246g23.4
chr16_+_17714664 0.38 ENSDART00000149042
si:dkey-87o1.2
chr22_-_10440688 0.38 ENSDART00000111962
nucleolar protein 8
chr11_+_16216909 0.38 ENSDART00000081035
ENSDART00000147190
solute carrier family 25 (S-adenosylmethionine carrier), member 26
chr7_+_20031202 0.38 ENSDART00000052904
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr18_+_20560442 0.38 ENSDART00000151990
WEE1 homolog 2 (S. pombe)
chr22_-_16154771 0.38 ENSDART00000009464
solute carrier family 30 (zinc transporter), member 7
chr4_+_22343093 0.38 ENSDART00000023588
guanylate cyclase activator 1A
chr10_+_8690936 0.38 ENSDART00000144218
si:dkey-27b3.4
chr23_+_2728095 0.38 ENSDART00000066086
zgc:114123
chr25_-_13188678 0.38 ENSDART00000125754
si:ch211-147m6.1
chr21_+_11244068 0.37 ENSDART00000163432
AT-rich interaction domain 6
chr1_+_56755536 0.37 ENSDART00000157727

chr5_+_27897504 0.37 ENSDART00000130936
ADAM metallopeptidase domain 28
chr2_+_36112273 0.37 ENSDART00000191315
T-cell receptor alpha joining 35
chr25_+_3326885 0.37 ENSDART00000104866
lactate dehydrogenase Bb
chr21_-_5881344 0.37 ENSDART00000009241
ribosomal protein L35
chr19_+_7152966 0.37 ENSDART00000080348
bromodomain containing 2a
chr14_+_32942063 0.37 ENSDART00000187705
ligand of numb-protein X 2b
chr21_-_42876565 0.37 ENSDART00000126480
zmp:0000001268
chr13_-_31025505 0.37 ENSDART00000137709
WDFY family member 4
chr10_-_34916208 0.37 ENSDART00000187371
cyclin A1
chr3_-_33427803 0.36 ENSDART00000075495
ribosomal protein L23
chr22_+_1821718 0.36 ENSDART00000132220
zinc finger protein 1002
chr1_-_23308225 0.36 ENSDART00000137567
ENSDART00000008201
small integral membrane protein 14
chr11_-_41853874 0.36 ENSDART00000002556
MRT4 homolog, ribosome maturation factor
chr14_+_35428152 0.36 ENSDART00000172597
synaptotagmin-like 4
chr12_-_46176115 0.36 ENSDART00000152848
si:ch211-226h7.8
chr6_-_10752937 0.36 ENSDART00000135093
Obg-like ATPase 1
chr19_-_42556086 0.36 ENSDART00000051731
si:dkey-267n13.1
chr23_-_31913069 0.36 ENSDART00000135526
mitochondrial fission regulator 2
chr3_+_32118670 0.36 ENSDART00000055287
ENSDART00000111688
zgc:109934
chr4_-_77140030 0.36 ENSDART00000174332
ENSDART00000190394
ENSDART00000189208


chr6_-_39270851 0.36 ENSDART00000148839
Rho guanine nucleotide exchange factor (GEF) 25b
chr13_+_24750078 0.35 ENSDART00000021053
collagen, type XVII, alpha 1b
chr17_+_8799451 0.35 ENSDART00000189814
ENSDART00000191577
tonsoku-like, DNA repair protein
chr13_-_25720876 0.35 ENSDART00000142404
ENSDART00000146487
si:dkey-192p21.6
chr1_+_52392511 0.35 ENSDART00000144025
si:ch211-217k17.8
chr11_+_18175893 0.35 ENSDART00000177625
zgc:173545
chr24_+_34069675 0.35 ENSDART00000143995
si:ch211-190p8.2
chr22_+_9806867 0.35 ENSDART00000137182
ENSDART00000106103
si:ch211-236g6.1
chr20_-_37813863 0.35 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr5_+_66433287 0.35 ENSDART00000170757
kinetochore associated 1
chr10_+_42358426 0.34 ENSDART00000025691
drebrin-like a
chr15_+_26603395 0.34 ENSDART00000188667
solute carrier family 47 (multidrug and toxin extrusion), member 3
chr17_-_14876758 0.34 ENSDART00000155857
nidogen 2a (osteonidogen)
chr18_-_40708537 0.34 ENSDART00000077577
si:ch211-132b12.8

Network of associatons between targets according to the STRING database.

First level regulatory network of meox2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0060631 regulation of meiosis I(GO:0060631)
0.3 1.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.3 0.9 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.3 0.8 GO:0016045 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.2 0.7 GO:0019556 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.2 1.4 GO:0001659 temperature homeostasis(GO:0001659)
0.2 1.0 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873)
0.2 0.7 GO:0034433 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.2 1.0 GO:0006545 glycine biosynthetic process(GO:0006545)
0.2 0.5 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.2 0.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.6 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.4 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.5 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.1 0.5 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.3 GO:0070589 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.1 0.5 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.1 0.5 GO:0046084 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.1 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.4 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.4 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.4 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.3 GO:0097435 fibril organization(GO:0097435)
0.1 0.3 GO:0030238 male sex determination(GO:0030238)
0.1 0.3 GO:0008344 adult locomotory behavior(GO:0008344)
0.1 0.7 GO:1902315 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.2 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093)
0.1 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 0.9 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.2 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045) hypoblast development(GO:0090008)
0.1 0.3 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.3 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 0.3 GO:0061549 sympathetic ganglion development(GO:0061549)
0.1 0.5 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.3 GO:0003190 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.1 0.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 0.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 0.3 GO:0003245 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.3 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.1 1.9 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 0.3 GO:0045598 regulation of fat cell differentiation(GO:0045598)
0.1 0.3 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.2 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.1 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.2 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.2 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 0.2 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.1 0.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 0.2 GO:0060292 long term synaptic depression(GO:0060292)
0.1 0.8 GO:0045740 positive regulation of DNA replication(GO:0045740)
0.1 0.2 GO:0060468 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.1 2.0 GO:0032355 response to estradiol(GO:0032355)
0.1 0.6 GO:0007143 female meiotic division(GO:0007143)
0.1 0.2 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531)
0.1 0.2 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.1 0.2 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.1 0.7 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.1 0.2 GO:0014005 microglia development(GO:0014005)
0.0 0.3 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.1 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.5 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.6 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.5 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.3 GO:0035909 aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.0 0.1 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.0 0.7 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.3 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.7 GO:0060046 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.7 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.1 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) RNA 5'-end processing(GO:0000966) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.3 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.1 GO:0046351 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.0 0.1 GO:0046104 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.8 GO:0015671 oxygen transport(GO:0015671)
0.0 0.3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.6 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.0 0.2 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.3 GO:0043090 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.0 0.1 GO:0089709 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.3 GO:0001878 response to yeast(GO:0001878)
0.0 0.3 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.2 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.2 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.4 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 1.3 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.6 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.6 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0000459 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.1 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.3 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.5 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0016246 RNA interference(GO:0016246) chromatin silencing by small RNA(GO:0031048)
0.0 0.2 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.5 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.1 GO:0006264 mitochondrial DNA replication(GO:0006264) mitochondrial DNA metabolic process(GO:0032042)
0.0 0.1 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 0.3 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.2 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.6 GO:0019835 cytolysis(GO:0019835)
0.0 0.3 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 1.7 GO:0007596 blood coagulation(GO:0007596)
0.0 0.9 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 1.1 GO:0007602 phototransduction(GO:0007602)
0.0 0.5 GO:0006298 mismatch repair(GO:0006298)
0.0 0.2 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.5 GO:0019432 triglyceride biosynthetic process(GO:0019432) neutral lipid biosynthetic process(GO:0046460) acylglycerol biosynthetic process(GO:0046463)
0.0 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.2 GO:0033198 response to ATP(GO:0033198)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:2000374 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.0 0.4 GO:0050727 regulation of inflammatory response(GO:0050727)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0006562 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) proline catabolic process(GO:0006562) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.3 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0097065 anterior head development(GO:0097065)
0.0 0.2 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.3 GO:0008354 germ cell migration(GO:0008354)
0.0 0.3 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.2 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.0 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.4 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.0 GO:0032196 transposition(GO:0032196)
0.0 0.1 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.3 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.0 1.1 GO:0072376 complement activation(GO:0006956) protein activation cascade(GO:0072376)
0.0 0.3 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.1 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.2 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.1 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.0 0.1 GO:0010159 specification of organ position(GO:0010159)
0.0 0.6 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.2 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.3 GO:0050795 regulation of behavior(GO:0050795)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.4 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.3 GO:0007634 optokinetic behavior(GO:0007634)
0.0 0.1 GO:1901185 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.7 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 0.1 GO:0006833 water transport(GO:0006833)
0.0 0.0 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.1 GO:0051341 regulation of oxidoreductase activity(GO:0051341)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.3 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.1 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.2 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 1.6 GO:0042627 chylomicron(GO:0042627)
0.1 0.4 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 0.5 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.7 GO:0071546 pi-body(GO:0071546)
0.1 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.3 GO:0005880 nuclear microtubule(GO:0005880)
0.1 0.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 4.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.2 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 1.0 GO:0042555 MCM complex(GO:0042555)
0.1 2.0 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.2 GO:0031673 H zone(GO:0031673)
0.1 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.4 GO:0071914 prominosome(GO:0071914)
0.0 0.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0097189 apoptotic body(GO:0097189)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 1.0 GO:0043186 P granule(GO:0043186)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 4.5 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.5 GO:0001726 ruffle(GO:0001726)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 1.3 GO:0005840 ribosome(GO:0005840)
0.0 0.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0009374 biotin binding(GO:0009374)
0.3 0.8 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.2 0.7 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 1.5 GO:0045735 nutrient reservoir activity(GO:0045735)
0.2 1.0 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 0.7 GO:0016841 ammonia-lyase activity(GO:0016841)
0.2 0.7 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 1.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.8 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.5 GO:0015369 calcium:proton antiporter activity(GO:0015369) metal ion:proton antiporter activity(GO:0051139)
0.1 0.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.7 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.7 GO:0032052 bile acid binding(GO:0032052)
0.1 0.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 3.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.3 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.3 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.1 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.7 GO:0030250 calcium sensitive guanylate cyclase activator activity(GO:0008048) cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 0.3 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 0.2 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.1 0.3 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.3 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.3 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.8 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.3 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.1 0.3 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.9 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.4 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.2 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.1 0.5 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.2 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.1 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.3 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.4 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.3 GO:0004104 cholinesterase activity(GO:0004104)
0.0 1.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.4 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.7 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 1.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.7 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.2 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.8 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.2 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0072545 odorant binding(GO:0005549) tyrosine binding(GO:0072545)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 5.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 0.5 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.7 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.0 0.1 GO:0008117 sphinganine-1-phosphate aldolase activity(GO:0008117)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 1.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.1 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.2 GO:0005223 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.3 GO:2001069 glycogen binding(GO:2001069)
0.0 0.3 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 4.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.9 GO:0019239 deaminase activity(GO:0019239)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.0 1.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 0.1 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.0 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0070697 activin receptor binding(GO:0070697)
0.0 1.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.2 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.2 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.7 GO:0005496 steroid binding(GO:0005496)
0.0 0.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.0 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.2 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 1.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.8 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 2.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 ST GAQ PATHWAY G alpha q Pathway
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.1 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.3 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 0.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 0.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 5.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.9 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.1 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma