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PRJNA207719: Tissue specific transcriptome profiling

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Results for mef2b

Z-value: 1.83

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Transcription factors associated with mef2b

Gene Symbol Gene ID Gene Info
ENSDARG00000093170 myocyte enhancer factor 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mef2bdr11_v1_chr22_+_18188045_181880450.682.0e-01Click!

Activity profile of mef2b motif

Sorted Z-values of mef2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_22930627 2.12 ENSDART00000187860
synaptophysin a
chr1_+_45080897 2.09 ENSDART00000129819
si:ch211-151p13.8
chr6_-_14139503 1.75 ENSDART00000089577
calcium channel, voltage-dependent, beta 4b subunit
chr1_+_8601935 1.73 ENSDART00000152367
si:ch211-160d14.6
chr5_-_31926906 1.67 ENSDART00000187340
slingshot protein phosphatase 1b
chr17_-_12336987 1.67 ENSDART00000172001
synaptosomal-associated protein, 25b
chr25_-_13381854 1.66 ENSDART00000164621
ENSDART00000169129
NDRG family member 4
chr10_-_22845485 1.58 ENSDART00000079454
vesicle-associated membrane protein 2
chr21_+_11684830 1.42 ENSDART00000147473
proprotein convertase subtilisin/kexin type 1
chr5_+_64368770 1.37 ENSDART00000162246
phospholipid phosphatase 7 (inactive)
chr21_+_11685009 1.35 ENSDART00000014668
proprotein convertase subtilisin/kexin type 1
chr10_-_8032885 1.30 ENSDART00000188619
ATPase H+ transporting V0 subunit a2a
chr3_-_61205711 1.27 ENSDART00000055062
parvalbumin 1
chr10_-_24371312 1.25 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr10_-_8033468 1.15 ENSDART00000140476
ATPase H+ transporting V0 subunit a2a
chr13_-_27767330 1.15 ENSDART00000131631
ENSDART00000112553
ENSDART00000189911
regulating synaptic membrane exocytosis 1a
chr14_-_32405387 1.14 ENSDART00000184647
fibroblast growth factor 13a
chr17_-_14671098 1.08 ENSDART00000037371
protein phosphatase 1, regulatory subunit 13Ba
chr19_-_31035155 1.08 ENSDART00000161882
basic leucine zipper and W2 domains 2
chr13_+_9432501 1.07 ENSDART00000058064
zgc:123321
chr5_-_10946232 1.07 ENSDART00000163139
ENSDART00000031265
reticulon 4 receptor
chr6_+_36942966 1.05 ENSDART00000028895
neuronal growth regulator 1
chr1_+_10683843 1.04 ENSDART00000054879
zgc:103678
chr10_-_2522588 1.03 ENSDART00000081926

chr25_-_29363934 1.02 ENSDART00000166889
neuroplastin a
chr6_-_10780698 0.99 ENSDART00000151714
G protein-coupled receptor 155b
chr21_-_12272543 0.98 ENSDART00000081510
ENSDART00000151297
CUGBP, Elav-like family member 4
chr9_-_33107237 0.93 ENSDART00000013918
calsequestrin 2
chr4_-_23908802 0.92 ENSDART00000138873
cugbp, Elav-like family member 2
chr23_+_22658700 0.91 ENSDART00000192248
enolase 1a, (alpha)
chr25_+_3677650 0.91 ENSDART00000154348
prion protein, related sequence 3
chr7_-_52334840 0.89 ENSDART00000174173

chr19_-_31035325 0.87 ENSDART00000147504
basic leucine zipper and W2 domains 2
chr10_-_2527342 0.84 ENSDART00000184168

chr18_+_7264961 0.83 ENSDART00000188461

chr21_-_27185915 0.83 ENSDART00000135052
solute carrier family 8 (sodium/calcium exchanger), member 4a
chr5_-_51819027 0.82 ENSDART00000164267
homer scaffolding protein 1b
chr1_-_25936677 0.82 ENSDART00000146488
ENSDART00000136321
myozenin 2b
chr20_+_41549200 0.80 ENSDART00000135715
family with sequence similarity 184, member A
chr25_-_27722614 0.80 ENSDART00000190154
zgc:153935
chr16_+_25245857 0.79 ENSDART00000155220
kelch-like family member 38b
chr19_-_41069573 0.78 ENSDART00000111982
ENSDART00000193142
sarcoglycan, epsilon
chr1_-_21483832 0.75 ENSDART00000102790
glycine receptor, beta a
chr12_-_34035364 0.73 ENSDART00000087065
TIMP metallopeptidase inhibitor 2a
chr25_+_29160102 0.72 ENSDART00000162854
pyruvate kinase M1/2b
chr11_+_11201096 0.71 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myomesin 2a
chr2_+_19777146 0.70 ENSDART00000038648
polypyrimidine tract binding protein 2b
chr9_+_29040425 0.69 ENSDART00000150201
si:ch73-116o1.2
chr21_+_39432248 0.66 ENSDART00000179938
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b
chr14_-_24332786 0.65 ENSDART00000173164
family with sequence similarity 13, member B
chr5_+_64842730 0.65 ENSDART00000144732
leucine rich repeat containing 8 VRAC subunit Ab
chr17_-_50234004 0.64 ENSDART00000058706
v-fos FBJ murine osteosarcoma viral oncogene homolog Aa
chr24_-_28333029 0.64 ENSDART00000149015
ENSDART00000129174
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr9_+_31795343 0.64 ENSDART00000139584
integrin, beta-like 1
chr5_+_51597677 0.64 ENSDART00000048210
ENSDART00000184797
creatine kinase, mitochondrial 2b (sarcomeric)
chr3_-_32818607 0.63 ENSDART00000075465
myosin light chain, phosphorylatable, fast skeletal muscle a
chr14_+_24215046 0.62 ENSDART00000079215
stanniocalcin 2a
chr5_-_72125551 0.60 ENSDART00000149412
SET and MYND domain containing 1a
chr5_-_18911114 0.59 ENSDART00000014434
bri3 binding protein
chr19_+_24394560 0.58 ENSDART00000142506
si:dkey-81h8.1
chr17_-_5769196 0.57 ENSDART00000113885
si:dkey-100n19.2
chr6_-_40722200 0.57 ENSDART00000035101
kelch repeat and BTB (POZ) domain containing 12
chr6_-_40722480 0.56 ENSDART00000188187
kelch repeat and BTB (POZ) domain containing 12
chr10_+_37145007 0.56 ENSDART00000131777
CUE domain containing 1a
chr10_+_29698467 0.55 ENSDART00000163402
discs, large homolog 2 (Drosophila)
chr6_+_46697710 0.55 ENSDART00000154969
thymocyte expressed, positive selection associated 1
chr20_-_26042070 0.55 ENSDART00000140255
si:dkey-12h9.6
chr6_-_35472923 0.55 ENSDART00000185907
regulator of G protein signaling 8
chr5_+_61657702 0.55 ENSDART00000134387
ENSDART00000171248
adaptor-related protein complex 2, beta 1 subunit
chr16_-_30655980 0.54 ENSDART00000146508
low density lipoprotein receptor class A domain containing 4b
chr23_+_23485858 0.53 ENSDART00000114067
agrin
chr3_-_18189283 0.53 ENSDART00000049240
transducer of ERBB2, 1a
chr7_-_23745984 0.53 ENSDART00000048050
zgc:92429
chr13_+_1944451 0.51 ENSDART00000125914
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1
chr12_+_34119439 0.50 ENSDART00000032821
cytohesin 1b
chr12_+_41697664 0.50 ENSDART00000162302
BCL2 interacting protein 3
chr8_-_26388090 0.49 ENSDART00000147912
si:dkey-20d21.12
chr19_+_41169996 0.49 ENSDART00000048438
ankyrin repeat and SOCS box containing 4
chr13_+_47710434 0.49 ENSDART00000188724
transmembrane protein 87B
chr16_-_26435431 0.47 ENSDART00000187526
multiple EGF-like-domains 8
chr7_-_49646251 0.47 ENSDART00000193674
-Ha-ras Harvey rat sarcoma viral oncogene homolog b
chr23_-_39849155 0.47 ENSDART00000115330
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr5_+_61658282 0.46 ENSDART00000188878
adaptor-related protein complex 2, beta 1 subunit
chr21_+_43559123 0.45 ENSDART00000151212
G protein-coupled receptor 185 a
chr6_-_46403475 0.44 ENSDART00000154148
calcium/calmodulin-dependent protein kinase Ia
chr23_-_32157865 0.44 ENSDART00000000876
nuclear receptor subfamily 4, group A, member 1
chr2_-_4787566 0.44 ENSDART00000160663
ENSDART00000157808
tyrosine kinase, non-receptor, 2b
chr8_-_53166975 0.42 ENSDART00000114683
rabenosyn, RAB effector
chr1_-_17569793 0.42 ENSDART00000125125
acyl-CoA synthetase long chain family member 1a
chr7_+_39006837 0.40 ENSDART00000173735
diacylglycerol kinase, zeta a
chr2_-_6182098 0.40 ENSDART00000156167
si:ch73-182a11.2
chr13_-_24825691 0.40 ENSDART00000142745
STE20-like kinase a
chr14_+_35901249 0.37 ENSDART00000105604
zgc:77938
chr9_+_32178374 0.37 ENSDART00000078576
coenzyme Q10B
chr12_+_8373525 0.35 ENSDART00000152180
AT-rich interaction domain 5B
chr2_-_37353098 0.35 ENSDART00000056522
SKI-like proto-oncogene a
chr5_-_50781623 0.35 ENSDART00000114950
zgc:194908
chr4_+_5180650 0.35 ENSDART00000067390
fibroblast growth factor 6b
chr9_-_23894392 0.35 ENSDART00000133417
ankyrin repeat and SOCS box containing 18
chr18_+_3169579 0.34 ENSDART00000164724
ENSDART00000186340
ENSDART00000181247
ENSDART00000168056
p21 protein (Cdc42/Rac)-activated kinase 1
chr24_-_32665283 0.34 ENSDART00000038364
carbonic anhydrase II
chr12_+_27022517 0.33 ENSDART00000152975
male-specific lethal 1 homolog b (Drosophila)
chr5_-_30151815 0.33 ENSDART00000156048
zinc finger and BTB domain containing 44
chr19_+_44039849 0.33 ENSDART00000086040
leucine rich repeat containing 14B
chr1_-_6494384 0.33 ENSDART00000109356
Kruppel-like factor 7a
chr17_-_23545716 0.32 ENSDART00000079534
5-hydroxytryptamine (serotonin) receptor 7a
chr4_-_5018705 0.32 ENSDART00000154025
striatin interacting protein 2
chr23_-_36670369 0.31 ENSDART00000006881
zinc finger and BTB domain containing 39
chr20_-_26001288 0.30 ENSDART00000136518
ENSDART00000063177
calpain 3b
chr9_-_48281941 0.30 ENSDART00000099787
kelch-like family member 41a
chr6_-_42003780 0.30 ENSDART00000032527
caveolin 3
chr19_-_7321221 0.30 ENSDART00000092375
oxidation resistance 1b
chr1_-_17570013 0.30 ENSDART00000146946
acyl-CoA synthetase long chain family member 1a
chr9_-_48937240 0.29 ENSDART00000075627
ceramide synthase 6
chr23_-_38497705 0.28 ENSDART00000109493
teashirt zinc finger homeobox 2
chr15_-_14552101 0.27 ENSDART00000171169
numb homolog (Drosophila)-like
chr24_+_9178064 0.27 ENSDART00000142971
discs, large (Drosophila) homolog-associated protein 1b
chr6_+_7555614 0.27 ENSDART00000187590
myosin, heavy chain 10, non-muscle
chr22_-_26852516 0.26 ENSDART00000005829
glycerophosphodiester phosphodiesterase 1
chr17_-_10025234 0.25 ENSDART00000008355
cofilin 2 (muscle)
chr21_+_19070921 0.25 ENSDART00000029874
NK6 homeobox 1
chr3_+_60828813 0.25 ENSDART00000128260

chr15_+_20543770 0.25 ENSDART00000092357
small G protein signaling modulator 2
chr2_-_33993533 0.24 ENSDART00000140910
ENSDART00000077304
patched 2
chr23_-_3721444 0.24 ENSDART00000141682
nudix (nucleoside diphosphate linked moiety X)-type motif 3a
chr5_-_31875645 0.23 ENSDART00000098160
transmembrane protein 119b
chr13_+_11439486 0.23 ENSDART00000138312
zinc finger and BTB domain containing 18
chr3_+_17456428 0.23 ENSDART00000090676
ENSDART00000182082
si:ch211-210g13.5
chr6_+_38896158 0.23 ENSDART00000029930
ENSDART00000131347
solute carrier family 48 (heme transporter), member 1b
chr5_+_16580739 0.22 ENSDART00000135140
5-hydroxytryptamine (serotonin) receptor 7c
chr1_-_411331 0.22 ENSDART00000092524
RAS p21 protein activator 3
chr7_-_30143092 0.22 ENSDART00000173636
FERM domain containing 5
chr6_-_6248893 0.22 ENSDART00000124662
reticulon 4a
chr10_-_41450367 0.22 ENSDART00000122682
ENSDART00000189549
calcium binding protein 1b
chr23_+_44497701 0.21 ENSDART00000149903
si:ch73-375g18.1
chr20_-_7000225 0.20 ENSDART00000100098
adenylate cyclase 1a
chr24_-_12745222 0.20 ENSDART00000151836
si:ch211-196f5.9
chr2_+_1202347 0.20 ENSDART00000075837

chr17_-_13026634 0.19 ENSDART00000113713
family with sequence similarity 177, member A1
chr23_+_6077503 0.19 ENSDART00000081714
ENSDART00000139834
myosin binding protein Ha
chr22_-_20259309 0.18 ENSDART00000139160
si:dkey-110c1.10
chr4_+_14343706 0.17 ENSDART00000142845
prolactin 2
chr6_+_40554551 0.17 ENSDART00000017859
ENSDART00000155928
DNA-damage inducible protein 2
chr8_+_7097929 0.17 ENSDART00000188955
ENSDART00000184772
ENSDART00000109581
ankyrin repeat and BTB (POZ) domain containing 1
chr3_+_32425202 0.17 ENSDART00000156464
proline rich 12b
chr25_-_29988352 0.17 ENSDART00000067059
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5b
chr22_+_2861734 0.16 ENSDART00000140578
si:dkey-20i20.2
chr18_+_49248389 0.16 ENSDART00000059285
ENSDART00000142004
ENSDART00000132751
Yip1 interacting factor homolog B (S. cerevisiae)
chr25_-_27722309 0.16 ENSDART00000148121
zgc:153935
chr12_-_26430507 0.14 ENSDART00000153214
synaptopodin 2-like b
chr7_-_27686021 0.14 ENSDART00000079112
ENSDART00000100989
calcitonin/calcitonin-related polypeptide, alpha
chr19_+_30990129 0.13 ENSDART00000052169
ENSDART00000193376
syncoilin, intermediate filament protein
chr5_+_51227147 0.13 ENSDART00000083340
UBA domain containing 1
chr9_+_32178050 0.13 ENSDART00000169526
coenzyme Q10B
chr3_-_13946446 0.13 ENSDART00000171249
glutaryl-CoA dehydrogenase b
chr25_+_32530976 0.12 ENSDART00000156190
ENSDART00000103324
S-phase cyclin A-associated protein in the ER
chr24_+_8904135 0.12 ENSDART00000066782
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr11_-_34478225 0.11 ENSDART00000189604
xyloside xylosyltransferase 1
chr13_+_42011287 0.10 ENSDART00000131147
cytochrome P450, family 1, subfamily B, polypeptide 1
chr9_-_52814204 0.10 ENSDART00000140771
ENSDART00000007401
si:ch211-45c16.2
chr14_-_7245971 0.10 ENSDART00000108796
storkhead box 2b
chr9_-_4018452 0.10 ENSDART00000181059
ubiquitin protein ligase E3 component n-recognin 3
chr1_+_59328030 0.10 ENSDART00000172464

chr3_-_52674089 0.10 ENSDART00000154260
ENSDART00000125455
si:dkey-210j14.4
chr4_-_4261673 0.09 ENSDART00000150694
CD9 molecule b
chr12_+_6002715 0.09 ENSDART00000114961
si:ch211-131k2.3
chr9_+_24065855 0.09 ENSDART00000161468
ENSDART00000171577
ENSDART00000172743
ENSDART00000159324
ENSDART00000079689
ENSDART00000023196
ENSDART00000101577
leucine rich repeat (in FLII) interacting protein 1a
chr7_+_20260172 0.09 ENSDART00000012450
dishevelled segment polarity protein 2
chr8_-_25002182 0.08 ENSDART00000078792
adenosylhomocysteinase-like 1
chr11_-_18601955 0.08 ENSDART00000180565
zinc finger, MYND-type containing 8
chr20_+_28407720 0.08 ENSDART00000114929
zinc finger, FYVE domain containing 1
chr9_+_21793565 0.08 ENSDART00000134915
REV1, polymerase (DNA directed)
chr19_-_38611814 0.06 ENSDART00000151958
collagen, type XVI, alpha 1
chr7_+_31379528 0.06 ENSDART00000187370
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2b
chr11_-_26701611 0.06 ENSDART00000083010
acyl-CoA dehydrogenase family, member 9
chr15_+_17343319 0.06 ENSDART00000018461
vacuole membrane protein 1
chr14_+_2487672 0.06 ENSDART00000170629
ENSDART00000123063
fibroblast growth factor 18a
chr6_-_25201810 0.05 ENSDART00000168683
leucine rich repeat containing 8 VRAC subunit C
chr1_+_19708508 0.05 ENSDART00000054581
ENSDART00000131206
membrane-associated ring finger (C3HC4) 1
chr21_+_40589770 0.05 ENSDART00000164650
ENSDART00000161584
ENSDART00000161108
pyruvate dehydrogenase kinase, isozyme 3b
chr25_-_19486399 0.05 ENSDART00000155076
ENSDART00000156016
zgc:193812
chr9_-_28399071 0.05 ENSDART00000104317
ENSDART00000064343
Kruppel-like factor 7b
chr13_-_36581875 0.05 ENSDART00000113204
lectin, galactoside binding soluble 3a
chr7_+_21859337 0.05 ENSDART00000159626
si:dkey-85k7.7
chr23_+_3721042 0.04 ENSDART00000143323
small integral membrane protein 29
chr2_+_35880600 0.04 ENSDART00000004277
laminin, gamma 1
chr1_-_45662774 0.03 ENSDART00000042158
serine hydrolase-like
chr12_+_30563550 0.03 ENSDART00000126064
si:ch211-28p3.4
chr5_-_25236340 0.03 ENSDART00000162774
ATP-binding cassette, sub-family A (ABC1), member 2
chr19_-_32518556 0.03 ENSDART00000103410
zinc finger and BTB domain containing 8B
chr25_-_12809361 0.03 ENSDART00000162750
carbonic anhydrase Va
chr20_+_45620076 0.03 ENSDART00000113806
heterogeneous nuclear ribonucleoprotein A0, like
chr24_+_25471196 0.03 ENSDART00000066625
small muscle protein, X-linked
chr16_-_17200120 0.02 ENSDART00000147739
glyceraldehyde-3-phosphate dehydrogenase
chr15_-_34866219 0.01 ENSDART00000099723
SH3-binding domain protein 5-like, a
chr24_+_26088143 0.01 ENSDART00000171129

chr23_-_7826849 0.01 ENSDART00000157612
myelin transcription factor 1b
chr4_+_13449775 0.01 ENSDART00000172552
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr18_+_17959681 0.01 ENSDART00000142700
zinc finger protein 423
chr8_+_29962635 0.00 ENSDART00000007640
patched 1

Network of associatons between targets according to the STRING database.

First level regulatory network of mef2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.9 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.2 2.8 GO:0016486 peptide hormone processing(GO:0016486)
0.2 0.5 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.2 0.9 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.2 0.5 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.2 2.5 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.2 0.7 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.5 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.5 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 1.7 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.1 0.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 1.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.3 GO:0097264 self proteolysis(GO:0097264)
0.1 0.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.8 GO:0042044 fluid transport(GO:0042044)
0.1 1.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.2 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.1 0.5 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.3 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 1.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 0.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.6 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 1.0 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.4 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.1 1.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.7 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.6 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.4 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:1901908 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.3 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 1.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.4 GO:0060612 adipose tissue development(GO:0060612)
0.0 1.0 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.3 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.3 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.2 GO:1901678 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.6 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 1.2 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.3 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.4 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.3 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.5 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.5 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.1 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 2.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 0.7 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.1 0.9 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.8 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.3 GO:0031430 M band(GO:0031430)
0.1 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 1.6 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.2 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 2.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.6 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.1 GO:0030426 growth cone(GO:0030426)
0.0 1.1 GO:0042383 sarcolemma(GO:0042383)
0.0 0.6 GO:0008305 integrin complex(GO:0008305)
0.0 1.0 GO:0030018 Z disc(GO:0030018)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.2 1.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 0.8 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 2.5 GO:0051117 ATPase binding(GO:0051117)
0.1 5.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.5 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 0.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.7 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.8 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 0.3 GO:0071253 connexin binding(GO:0071253)
0.1 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.1 1.1 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.7 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 1.1 GO:0002039 p53 binding(GO:0002039)
0.1 1.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.5 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.6 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.2 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 1.0 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0004361 glutaryl-CoA dehydrogenase activity(GO:0004361)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.2 GO:0044325 ion channel binding(GO:0044325)
0.0 0.6 GO:0016208 AMP binding(GO:0016208)
0.0 1.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0070330 aromatase activity(GO:0070330)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.5 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 2.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0043236 laminin binding(GO:0043236)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.0 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.0 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3 2.8 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 1.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis