Project
PRJNA207719: Tissue specific transcriptome profiling
Navigation
Downloads
Results for mef2b
Z-value: 1.83
Motif logo
Transcription factors associated with mef2b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| mef2b | dr11_v1_chr22_+_18188045_18188045 | 0.68 | 2.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_+_22930627 Show fit | 2.12 |
ENSDART00000187860
|
synaptophysin a |
|
| chr1_+_45080897 Show fit | 2.09 |
ENSDART00000129819
|
si:ch211-151p13.8 |
|
| chr6_-_14139503 Show fit | 1.75 |
ENSDART00000089577
|
calcium channel, voltage-dependent, beta 4b subunit |
|
| chr1_+_8601935 Show fit | 1.73 |
ENSDART00000152367
|
si:ch211-160d14.6 |
|
| chr5_-_31926906 Show fit | 1.67 |
ENSDART00000187340
|
slingshot protein phosphatase 1b |
|
| chr17_-_12336987 Show fit | 1.67 |
ENSDART00000172001
|
synaptosomal-associated protein, 25b |
|
| chr25_-_13381854 Show fit | 1.66 |
ENSDART00000164621
ENSDART00000169129 |
NDRG family member 4 |
|
| chr10_-_22845485 Show fit | 1.58 |
ENSDART00000079454
|
vesicle-associated membrane protein 2 |
|
| chr21_+_11684830 Show fit | 1.42 |
ENSDART00000147473
|
proprotein convertase subtilisin/kexin type 1 |
|
| chr5_+_64368770 Show fit | 1.37 |
ENSDART00000162246
|
phospholipid phosphatase 7 (inactive) |
Network of associatons between targets according to the STRING database.
First level regulatory network of mef2b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.3 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.2 | 2.8 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.2 | 2.5 | GO:0007035 | vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452) |
| 0.1 | 1.7 | GO:0015858 | nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642) |
| 0.0 | 1.7 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.1 | 1.6 | GO:0035493 | SNARE complex assembly(GO:0035493) |
| 0.1 | 1.3 | GO:0048936 | peripheral nervous system neuron axonogenesis(GO:0048936) |
| 0.1 | 1.2 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.0 | 1.2 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.1 | 1.1 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.5 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.0 | 2.1 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.3 | 1.7 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.0 | 1.7 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 1.6 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 1.3 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 1.2 | GO:0048788 | cytoskeleton of presynaptic active zone(GO:0048788) |
| 0.0 | 1.1 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 1.1 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.0 | 1.0 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.4 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 2.8 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.2 | 2.5 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.2 | 1.7 | GO:0008504 | monoamine transmembrane transporter activity(GO:0008504) |
| 0.1 | 1.7 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.0 | 1.7 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.2 | 1.2 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.0 | 1.2 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.1 | 1.1 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.1 | 1.1 | GO:0002039 | p53 binding(GO:0002039) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 1.0 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 0.7 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.0 | 0.6 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.4 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.3 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.0 | 0.3 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 0.2 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 2.8 | REACTOME PEPTIDE HORMONE BIOSYNTHESIS | Genes involved in Peptide hormone biosynthesis |
| 0.5 | 1.6 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.1 | 1.0 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.0 | 0.5 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.4 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 0.4 | REACTOME PIP3 ACTIVATES AKT SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.0 | 0.3 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.0 | 0.3 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 0.3 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.1 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |