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PRJNA207719: Tissue specific transcriptome profiling

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Results for mecp2

Z-value: 2.42

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Transcription factors associated with mecp2

Gene Symbol Gene ID Gene Info
ENSDARG00000014218 methyl CpG binding protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mecp2dr11_v1_chr8_-_7637626_76376400.662.2e-01Click!

Activity profile of mecp2 motif

Sorted Z-values of mecp2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_13685047 2.28 ENSDART00000018351
zgc:65851
chr8_+_16004154 2.18 ENSDART00000134787
ENSDART00000172510
ENSDART00000141173
ELAV like neuron-specific RNA binding protein 4
chr22_+_11535131 2.14 ENSDART00000113930
neuropeptide B
chr9_-_31278048 2.05 ENSDART00000022204
zic family member 5 (odd-paired homolog, Drosophila)
chr8_-_25422186 2.01 ENSDART00000113492
ENSDART00000131736
potassium voltage-gated channel, KQT-like subfamily, member 2a
chr12_-_29624638 1.85 ENSDART00000126744
neuregulin 3b
chr16_+_32559821 1.79 ENSDART00000093250
POU class 3 homeobox 2b
chr3_+_31396149 1.78 ENSDART00000151423
ENSDART00000193580
complement component 1, q subcomponent-like 3b
chr5_+_64739762 1.76 ENSDART00000161112
ENSDART00000135610
ENSDART00000002908
olfactomedin 1a
chr19_+_232536 1.66 ENSDART00000137880
synaptic Ras GTPase activating protein 1a
chr4_+_19534833 1.65 ENSDART00000140028
leucine rich repeat containing 4.1
chr1_+_31864404 1.61 ENSDART00000075260
internexin neuronal intermediate filament protein, alpha b
chr8_+_31119548 1.59 ENSDART00000136578
synapsin I
chr19_+_5072918 1.57 ENSDART00000037126
enolase 2
chr8_+_16004551 1.56 ENSDART00000165141
ELAV like neuron-specific RNA binding protein 4
chr15_+_39096736 1.52 ENSDART00000129511
ENSDART00000014877
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr1_+_12766351 1.43 ENSDART00000165785
protocadherin 10a
chr2_+_27491066 1.42 ENSDART00000078305
zinc finger, SWIM-type containing 5
chr20_-_45661049 1.42 ENSDART00000124582
ENSDART00000131251
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr17_-_6759006 1.41 ENSDART00000184692
ENSDART00000180530
visinin-like 1b
chr25_-_19443421 1.38 ENSDART00000067362
cocaine- and amphetamine-regulated transcript 2
chr3_+_35005062 1.38 ENSDART00000181163
protein kinase C, beta b
chr19_-_47587719 1.37 ENSDART00000111108

chr23_+_2361184 1.37 ENSDART00000184469

chr21_-_10446405 1.33 ENSDART00000167948
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr11_-_762721 1.30 ENSDART00000166465
synapsin IIb
chr18_-_46881108 1.28 ENSDART00000190084
GRAM domain containing 1Bb
chr17_-_19022990 1.28 ENSDART00000154186
fibronectin leucine rich transmembrane protein 2
chr4_-_1360495 1.24 ENSDART00000164623
pleiotrophin
chr6_+_41554794 1.24 ENSDART00000165424
SLIT-ROBO Rho GTPase activating protein 3
chr20_-_30035326 1.22 ENSDART00000141068
SRY (sex determining region Y)-box 11b
chr9_+_24159725 1.22 ENSDART00000137756
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a
chr1_-_40994259 1.20 ENSDART00000101562
adrenoceptor alpha 2C
chr19_+_56351 1.19 ENSDART00000168334
collagen, type XIV, alpha 1b
chr8_+_47897734 1.18 ENSDART00000140266
mitofusin 2
chr20_+_22666548 1.15 ENSDART00000147520
ligand of numb-protein X 1
chr10_-_22845485 1.15 ENSDART00000079454
vesicle-associated membrane protein 2
chr25_+_8063455 1.13 ENSDART00000073919
potassium voltage-gated channel, Shaw-related subfamily, member 1b
chr3_+_46724528 1.11 ENSDART00000181358
phosphodiesterase 4A, cAMP-specific
chr12_+_33038757 1.09 ENSDART00000153146
RNA binding fox-1 homolog 3a
chr3_-_27880229 1.09 ENSDART00000151404
4-aminobutyrate aminotransferase
chr9_+_17787864 1.08 ENSDART00000013111
diacylglycerol kinase, eta
chr16_-_29458806 1.07 ENSDART00000047931
leucine rich repeat and Ig domain containing 4b
chr1_-_20911297 1.07 ENSDART00000078271
carboxypeptidase E
chr20_+_32523576 1.06 ENSDART00000147319
Scm polycomb group protein like 4
chr13_-_40120252 1.05 ENSDART00000157852
cartilage acidic protein 1b
chr17_+_28883353 1.04 ENSDART00000110322
protein kinase D1
chr14_-_2355833 1.04 ENSDART00000157677
si:ch73-233f7.6
chr13_-_36911118 1.04 ENSDART00000048739
tripartite motif containing 9
chr7_+_19552381 1.04 ENSDART00000169060
si:ch211-212k18.5
chr2_+_34572690 1.03 ENSDART00000077216
astrotactin 1
chr4_+_23223881 1.03 ENSDART00000133056
ENSDART00000089126
thyrotropin releasing hormone degrading enzyme, tandem duplicate 1
chr8_+_23165749 1.00 ENSDART00000063057
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr14_-_2050057 1.00 ENSDART00000112875
protocadherin beta 15
chr22_-_13544244 1.00 ENSDART00000110136
contactin associated protein-like 5b
chr9_-_18877597 0.99 ENSDART00000099446
potassium channel tetramerization domain containing 4
chr16_-_31188715 0.99 ENSDART00000058829
scratch family zinc finger 1b
chr14_-_9199968 0.98 ENSDART00000146113
Cdc42 guanine nucleotide exchange factor (GEF) 9b
chr2_-_50372467 0.98 ENSDART00000108900
contactin associated protein like 2b
chr18_+_5917625 0.94 ENSDART00000169100
golgi glycoprotein 1b
chr20_-_47704973 0.93 ENSDART00000174808
transcription factor AP-2 beta
chr1_+_54908895 0.92 ENSDART00000145652
golgin A7 family, member Ba
chr16_+_34528409 0.90 ENSDART00000144718
progestin and adipoQ receptor family member VII, b
chr1_+_25783801 0.90 ENSDART00000102455
guanylate cyclase 1 soluble subunit alpha 1
chr11_-_27917730 0.90 ENSDART00000173219
eukaryotic translation initiation factor 4 gamma, 3a
chr17_-_28198099 0.89 ENSDART00000156143
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr4_-_12102025 0.89 ENSDART00000048391
ENSDART00000023894
B-Raf proto-oncogene, serine/threonine kinase
chr21_-_42100471 0.89 ENSDART00000166148
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr15_+_28685625 0.89 ENSDART00000188797
ENSDART00000166036
neuro-oncological ventral antigen 2
chr5_-_28606916 0.88 ENSDART00000026107
ENSDART00000137717
tenascin C
chr25_-_34156152 0.88 ENSDART00000125036
forkhead box B1a
chr19_-_9503473 0.87 ENSDART00000091615
intermediate filament family orphan 1a
chr17_+_28882977 0.86 ENSDART00000153937
protein kinase D1
chr10_+_39476600 0.86 ENSDART00000135756
kirre like nephrin family adhesion molecule 3a
chr24_+_5208171 0.85 ENSDART00000155926
ENSDART00000154464
si:ch73-206p6.1
chr8_+_21146262 0.84 ENSDART00000045684
porcupine O-acyltransferase
chr20_+_474288 0.84 ENSDART00000026794
5'-nucleotidase domain containing 1
chr15_+_45994123 0.81 ENSDART00000124704
leucine rich repeat and fibronectin type III domain containing 1
chr15_+_40188076 0.81 ENSDART00000063779
EF-hand domain family, member D1
chr11_-_37589293 0.81 ENSDART00000172989
bassoon (presynaptic cytomatrix protein) b
chr3_+_17806213 0.81 ENSDART00000055890
zinc finger protein 385C
chr20_+_52389858 0.81 ENSDART00000185863
ENSDART00000166651
Rho GTPase activating protein 39
chr20_-_47732703 0.81 ENSDART00000193975
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr16_-_12914288 0.80 ENSDART00000184221
calcium channel, voltage-dependent, gamma subunit 8b
chr6_-_21988375 0.80 ENSDART00000161257
plexin b1b
chr18_+_28564640 0.80 ENSDART00000016983
spondin 1a
chr3_-_5664123 0.80 ENSDART00000145866
si:ch211-106h11.1
chr8_+_48966165 0.79 ENSDART00000165425
AP2 associated kinase 1a
chr24_+_24461558 0.78 ENSDART00000182424
basic helix-loop-helix family, member e22
chr5_-_29488245 0.78 ENSDART00000047719
ENSDART00000141154
ENSDART00000171165
calcium channel, voltage-dependent, N type, alpha 1B subunit, a
chr15_+_28685892 0.78 ENSDART00000155815
ENSDART00000060244
neuro-oncological ventral antigen 2
chr19_+_32979331 0.77 ENSDART00000078066
spire-type actin nucleation factor 1a
chr6_+_39222598 0.77 ENSDART00000154991
beta-1,4-N-acetyl-galactosaminyl transferase 1b
chr15_-_18138607 0.77 ENSDART00000176690

chr9_-_55790458 0.76 ENSDART00000161247
sosondowah ankyrin repeat domain family Ca
chr20_-_31905968 0.76 ENSDART00000142806
syntaxin binding protein 5a (tomosyn)
chr8_-_30979494 0.75 ENSDART00000138959
si:ch211-251j10.3
chr8_-_22739757 0.74 ENSDART00000182167
ENSDART00000171891
IQ motif and Sec7 domain 2a
chr13_-_36545258 0.71 ENSDART00000186171

chr18_+_45228691 0.71 ENSDART00000127953
LARGE xylosyl- and glucuronyltransferase 2
chr6_+_58406014 0.70 ENSDART00000044241
potassium voltage-gated channel, KQT-like subfamily, member 2b
chr4_+_20263097 0.70 ENSDART00000138820
leucine-rich repeats and transmembrane domains 2a
chr15_-_47895200 0.70 ENSDART00000027060
zmp:0000000529
chr14_+_5936996 0.69 ENSDART00000097144
ENSDART00000126777
potassium channel tetramerization domain containing 8
chr13_-_36184476 0.69 ENSDART00000057185
mitogen-activated protein kinase kinase kinase 9
chr16_+_1353894 0.68 ENSDART00000148426
cugbp, Elav-like family member 3b
chr14_-_27289042 0.68 ENSDART00000159727
protocadherin 11
chr23_+_28128453 0.68 ENSDART00000182618
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a
chr2_-_37401600 0.67 ENSDART00000015723
protein kinase C, iota
chr19_+_37458610 0.67 ENSDART00000103151
discs, large (Drosophila) homolog-associated protein 3
chr21_+_28728030 0.65 ENSDART00000097307
purine-rich element binding protein Aa
chr15_-_45110011 0.65 ENSDART00000182047
ENSDART00000188662

chr25_-_20381107 0.65 ENSDART00000067454
potassium channel tetramerization domain containing 15a
chr5_+_59397739 0.65 ENSDART00000148659
CAP-GLY domain containing linker protein 2
chr2_-_32501501 0.65 ENSDART00000181309
Fas apoptotic inhibitory molecule 2a
chr17_+_52300018 0.64 ENSDART00000190302
estrogen-related receptor beta
chr7_-_24699985 0.63 ENSDART00000052802
calbindin 2b
chr2_+_39108339 0.63 ENSDART00000085675
calsyntenin 2
chr10_-_43392667 0.63 ENSDART00000183033
EGF-like repeats and discoidin I-like domains 3b
chr17_+_43629008 0.63 ENSDART00000184185
ENSDART00000181681
zinc finger protein 365
chr14_-_2196267 0.62 ENSDART00000161674
ENSDART00000125674
protocadherin 2 alpha b 8
protocadherin 2 alpha b 9
chr7_+_1442059 0.62 ENSDART00000173391
si:cabz01090193.1
chr5_+_26079178 0.60 ENSDART00000145920
si:dkey-201c13.2
chr25_-_12203952 0.60 ENSDART00000158204
ENSDART00000091727
neurotrophic tyrosine kinase, receptor, type 3a
chr25_+_17589906 0.60 ENSDART00000167750
vac14 homolog (S. cerevisiae)
chr21_-_37790727 0.60 ENSDART00000162907
gamma-aminobutyric acid (GABA) A receptor, beta 4
chr15_+_23208042 0.60 ENSDART00000006085
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr15_+_2559875 0.59 ENSDART00000178505
SH2B adaptor protein 2
chr7_-_26389908 0.59 ENSDART00000109268
si:dkey-3k24.5
chr19_-_32914227 0.59 ENSDART00000186115
ENSDART00000124246
metadherin a
chr6_+_48664275 0.59 ENSDART00000161184
si:dkey-238f9.1
chr3_+_13637383 0.58 ENSDART00000166000
si:ch211-194b1.1
chr3_-_35602233 0.58 ENSDART00000055269
guanine nucleotide binding protein (G protein), gamma 13b
chr2_+_50391331 0.58 ENSDART00000098108
vimentin like
chr25_-_20381271 0.58 ENSDART00000142665
potassium channel tetramerization domain containing 15a
chr2_+_40294313 0.58 ENSDART00000037292
eph receptor A4b
chr12_+_25640480 0.57 ENSDART00000105608
protein kinase C, epsilon a
chr2_+_23222939 0.57 ENSDART00000026800
kinesin-associated protein 3b
chr6_-_57722816 0.57 ENSDART00000186163
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr3_+_22059066 0.57 ENSDART00000155739
KAT8 regulatory NSL complex subunit 1b
chr13_+_14006118 0.57 ENSDART00000131875
ENSDART00000089528
attractin
chr5_-_43935460 0.56 ENSDART00000166152
ENSDART00000188969
si:ch211-204c21.1
chr15_+_44093286 0.56 ENSDART00000114352
zgc:112998
chr3_+_40856095 0.56 ENSDART00000143207
monocyte to macrophage differentiation-associated 2a
chr9_+_1505206 0.56 ENSDART00000093427
ENSDART00000137230
phosphodiesterase 11a
chr11_+_39969048 0.56 ENSDART00000193693
period circadian clock 3
chr19_+_42754882 0.55 ENSDART00000133711
cytoplasmic linker associated protein 2
chr24_-_20808283 0.55 ENSDART00000143759
vasoactive intestinal peptide receptor 1b
chr17_+_24318753 0.55 ENSDART00000064083
orthodenticle homeobox 1
chr19_+_3056450 0.54 ENSDART00000141324
ENSDART00000082353
heat shock transcription factor 1
chr22_-_38607504 0.54 ENSDART00000164609
si:ch211-126j24.1
chr15_-_45246911 0.53 ENSDART00000189557
ENSDART00000185291

chr10_-_41156348 0.53 ENSDART00000058622
AP2 associated kinase 1b
chr7_+_19882066 0.53 ENSDART00000111144
transmembrane protein 151A
chr24_+_792429 0.52 ENSDART00000082523
inositol(myo)-1(or 4)-monophosphatase 2
chr17_-_21441464 0.52 ENSDART00000031490
ventral anterior homeobox 1
chr25_+_2776511 0.52 ENSDART00000115280
neogenin 1b
chr19_+_14454306 0.52 ENSDART00000161965
zinc finger, DHHC-type containing 18b
chr1_-_53407448 0.52 ENSDART00000160033
ENSDART00000172322
ELMO/CED-12 domain containing 2
chr2_+_23823622 0.50 ENSDART00000099581
si:dkey-24c2.9
chr15_+_32798333 0.50 ENSDART00000162370
ENSDART00000166525
spartin b
chr12_-_13966184 0.50 ENSDART00000066368
kelch-like family member 11
chr23_+_30859086 0.50 ENSDART00000053661
zgc:198371
chr10_+_39476432 0.49 ENSDART00000190375
ENSDART00000183954
kirre like nephrin family adhesion molecule 3a
chr5_-_24712405 0.49 ENSDART00000033630
si:ch211-106a19.1
chr10_-_22057001 0.49 ENSDART00000016575
T cell leukemia homeobox 3b
chr10_+_26118122 0.48 ENSDART00000079207
tripartite motif containing 47
chr11_-_21363834 0.48 ENSDART00000080051
si:dkey-85p17.3
chr11_-_23322182 0.48 ENSDART00000111289
KiSS-1 metastasis-suppressor
chr5_+_69950882 0.48 ENSDART00000097359
DnaJ (Hsp40) homolog, subfamily C , member 25
chr4_-_24019711 0.47 ENSDART00000077926
cugbp, Elav-like family member 2
chr21_+_10021823 0.47 ENSDART00000163995
hect domain and RLD 7
chr7_+_32021669 0.46 ENSDART00000173976
methyltransferase like 15
chr1_-_23557877 0.46 ENSDART00000145942
family with sequence similarity 184, member B
chr24_-_6345647 0.46 ENSDART00000108994
zgc:174877
chr2_+_38147761 0.45 ENSDART00000135307
spalt-like transcription factor 2
chr9_-_32158288 0.45 ENSDART00000037182
ankyrin repeat domain 44
chr25_+_3994823 0.45 ENSDART00000154020
EPS8 like 2
chr20_+_52458765 0.45 ENSDART00000057980
tissue specific transplantation antigen P35B
chr3_-_23596532 0.44 ENSDART00000124921
ubiquitin-conjugating enzyme E2Z
chr3_-_13068189 0.43 ENSDART00000167180
protein kinase, cAMP-dependent, regulatory, type I, beta
chr15_-_30815826 0.43 ENSDART00000156160
ENSDART00000145918
musashi RNA-binding protein 2b
chr10_-_2682198 0.43 ENSDART00000183727
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr10_+_34377697 0.43 ENSDART00000189441
StAR-related lipid transfer (START) domain containing 13a
chr5_-_52277643 0.43 ENSDART00000010757
repulsive guidance molecule family member b
chr10_-_27196093 0.43 ENSDART00000185282
autism susceptibility candidate 2a
chr18_-_16590056 0.43 ENSDART00000143744
mgat4 family, member C
chr18_-_46881682 0.43 ENSDART00000189653
GRAM domain containing 1Bb
chr4_-_9764767 0.43 ENSDART00000164328
ENSDART00000147699
microtubule associated monooxygenase, calponin and LIM domain containing 3b
chr11_+_2687395 0.43 ENSDART00000082510
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr3_+_311833 0.42 ENSDART00000187375

chr8_+_2757821 0.42 ENSDART00000051403
ENSDART00000160551
SH3-domain GRB2-like endophilin B2a
chr19_-_27830818 0.42 ENSDART00000131767
PAP associated domain containing 7
chr13_-_44782462 0.42 ENSDART00000141298
ENSDART00000099990
BTB (POZ) domain containing 9
chr22_-_20166660 0.42 ENSDART00000085913
ENSDART00000188241
BTB (POZ) domain containing 2a
chr20_-_47731768 0.41 ENSDART00000031167
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr21_-_18824434 0.41 ENSDART00000156333
si:dkey-112m2.1
chr18_-_20560007 0.41 ENSDART00000141367
ENSDART00000090186
si:ch211-238n5.4
chr5_-_41307550 0.40 ENSDART00000143446
natriuretic peptide receptor 3
chr11_-_2594045 0.40 ENSDART00000114079
NGFI-A binding protein 2 (EGR1 binding protein 2)

Network of associatons between targets according to the STRING database.

First level regulatory network of mecp2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.3 1.9 GO:0089700 protein kinase D signaling(GO:0089700) regulation of lymphangiogenesis(GO:1901490)
0.3 0.9 GO:0045887 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.3 2.0 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.3 0.8 GO:0061355 Wnt protein secretion(GO:0061355)
0.2 1.2 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.2 1.1 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.2 0.6 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.2 1.0 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.2 1.8 GO:1902868 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.2 0.9 GO:0070208 protein heterotrimerization(GO:0070208)
0.2 0.9 GO:0007412 axon target recognition(GO:0007412) hypothalamus cell migration(GO:0021855)
0.2 1.4 GO:0008343 adult feeding behavior(GO:0008343)
0.2 0.7 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.2 0.7 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.2 1.2 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.2 0.6 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.2 1.2 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.2 1.5 GO:0050975 sensory perception of touch(GO:0050975)
0.1 0.4 GO:0008344 adult locomotory behavior(GO:0008344)
0.1 1.3 GO:0035677 posterior lateral line neuromast hair cell development(GO:0035677)
0.1 0.9 GO:0090594 inflammatory response to wounding(GO:0090594)
0.1 0.3 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.1 0.6 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.1 1.2 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.4 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.1 0.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 2.1 GO:0007631 feeding behavior(GO:0007631)
0.1 0.8 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 0.4 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.3 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 1.4 GO:0097324 melanocyte migration(GO:0097324)
0.1 1.5 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.3 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.5 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1 0.6 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.1 0.8 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.9 GO:0050795 regulation of behavior(GO:0050795)
0.1 1.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.2 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.2 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.1 0.3 GO:0061032 visceral serous pericardium development(GO:0061032)
0.1 0.4 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.1 0.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.3 GO:0032801 receptor catabolic process(GO:0032801)
0.1 0.3 GO:0071867 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.1 0.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.3 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.6 GO:0050909 sensory perception of taste(GO:0050909)
0.1 1.0 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.2 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.2 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.0 0.8 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.0 1.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.7 GO:0050919 negative chemotaxis(GO:0050919)
0.0 3.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.2 GO:0031087 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.7 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 1.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:1903010 regulation of bone development(GO:1903010)
0.0 0.1 GO:0000390 spliceosomal complex disassembly(GO:0000390) ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.3 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.0 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0042779 tRNA 3'-trailer cleavage(GO:0042779)
0.0 0.6 GO:1990089 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0 0.2 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 0.2 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.6 GO:0045807 positive regulation of endocytosis(GO:0045807)
0.0 1.6 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 1.0 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.5 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.0 0.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.6 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968) postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.7 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.6 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.9 GO:0009648 photoperiodism(GO:0009648)
0.0 1.3 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 3.4 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.8 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.4 GO:0007416 synapse assembly(GO:0007416)
0.0 0.2 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.2 GO:0010830 regulation of myotube differentiation(GO:0010830) regulation of skeletal muscle fiber development(GO:0048742)
0.0 1.3 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.5 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.0 0.6 GO:0009408 response to heat(GO:0009408)
0.0 2.5 GO:0099643 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 1.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 0.1 GO:0006747 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.0 0.2 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.4 GO:0021884 forebrain neuron development(GO:0021884)
0.0 1.4 GO:1902667 regulation of axon guidance(GO:1902667)
0.0 0.5 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0045176 asymmetric protein localization(GO:0008105) apical protein localization(GO:0045176)
0.0 0.2 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.3 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.2 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.0 0.2 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0061157 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.0 0.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0042694 muscle cell fate specification(GO:0042694)
0.0 3.5 GO:0034765 regulation of ion transmembrane transport(GO:0034765)
0.0 0.1 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.3 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0071711 basement membrane organization(GO:0071711)
0.0 0.9 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.5 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 5.5 GO:0048812 neuron projection morphogenesis(GO:0048812)
0.0 0.2 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.4 GO:0070936 protein K48-linked ubiquitination(GO:0070936)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 GO:0043194 axon initial segment(GO:0043194)
0.4 1.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.3 1.6 GO:0005883 neurofilament(GO:0005883)
0.1 1.0 GO:0033010 paranodal junction(GO:0033010)
0.1 1.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 3.7 GO:0043204 perikaryon(GO:0043204)
0.1 0.8 GO:0098982 GABA-ergic synapse(GO:0098982)
0.1 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.1 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.6 GO:0035032 extrinsic component of vacuolar membrane(GO:0000306) phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.2 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1 0.3 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 0.9 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.4 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 0.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.5 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.0 GO:0035371 microtubule plus-end(GO:0035371)
0.0 4.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0044545 NSL complex(GO:0044545)
0.0 0.6 GO:0043195 terminal bouton(GO:0043195)
0.0 2.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.0 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.6 GO:0045180 basal cortex(GO:0045180)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0016586 RSC complex(GO:0016586)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.6 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.2 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 1.5 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 0.6 GO:0030882 lipid antigen binding(GO:0030882)
0.2 1.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.2 0.6 GO:0047690 aspartyltransferase activity(GO:0047690)
0.2 1.4 GO:0035173 histone kinase activity(GO:0035173)
0.2 0.5 GO:0052834 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 0.7 GO:0048531 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 3.2 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 1.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.4 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.6 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.3 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.7 GO:0030552 cAMP binding(GO:0030552)
0.1 0.6 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 3.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.7 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 0.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.9 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.7 GO:0042285 xylosyltransferase activity(GO:0042285)
0.1 0.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.3 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.9 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 1.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.8 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.7 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.1 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0008126 acetylesterase activity(GO:0008126)
0.0 0.3 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.9 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 1.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.6 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.9 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.4 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.4 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.9 GO:0044325 ion channel binding(GO:0044325)
0.0 1.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.8 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.0 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.0 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 1.7 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID IGF1 PATHWAY IGF1 pathway
0.1 0.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 0.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 1.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.6 PID INSULIN PATHWAY Insulin Pathway
0.0 0.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.8 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 0.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 1.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 0.7 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 1.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 3.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 0.6 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.3 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions