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PRJNA207719: Tissue specific transcriptome profiling
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Results for mafk
Z-value: 1.62
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Transcription factors associated with mafk
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| mafk | dr11_v1_chr3_-_42967698_42967698 | 0.64 | 2.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_2020044 Show fit | 1.25 |
ENSDART00000024135
|
tubulin, beta 2A class IIa |
|
| chr13_+_35746440 Show fit | 1.23 |
ENSDART00000187859
|
G protein-coupled receptor 75 |
|
| chr16_-_16182319 Show fit | 1.18 |
ENSDART00000103815
|
stathmin 2a |
|
| chr19_+_31771270 Show fit | 1.07 |
ENSDART00000147474
|
stathmin 2b |
|
| chr3_-_32818607 Show fit | 0.99 |
ENSDART00000075465
|
myosin light chain, phosphorylatable, fast skeletal muscle a |
|
| chr10_+_4235998 Show fit | 0.91 |
ENSDART00000169328
|
phospholipid phosphatase related 1 |
|
| chr12_-_4683325 Show fit | 0.90 |
ENSDART00000152771
|
si:ch211-255p10.3 |
|
| chr22_-_13857729 Show fit | 0.90 |
ENSDART00000177971
|
S100 calcium binding protein, beta (neural) |
|
| chr23_-_15878879 Show fit | 0.89 |
ENSDART00000010119
|
eukaryotic translation elongation factor 1 alpha 2 |
|
| chr15_+_37559570 Show fit | 0.88 |
ENSDART00000085522
|
heat shock protein, alpha-crystallin-related, b6 |
Network of associatons between targets according to the STRING database.
First level regulatory network of mafk
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.9 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.3 | 1.3 | GO:0021557 | oculomotor nerve development(GO:0021557) |
| 0.0 | 1.2 | GO:0032233 | positive regulation of actin filament bundle assembly(GO:0032233) |
| 0.0 | 1.0 | GO:0046839 | phospholipid dephosphorylation(GO:0046839) |
| 0.1 | 0.9 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.0 | 0.9 | GO:0036376 | cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436) |
| 0.0 | 0.9 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 0.9 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.9 | GO:0006414 | translational elongation(GO:0006414) |
| 0.0 | 0.8 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.3 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 1.3 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.0 | 1.2 | GO:0036379 | striated muscle thin filament(GO:0005865) myofilament(GO:0036379) |
| 0.0 | 1.1 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.1 | 0.9 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.0 | 0.9 | GO:0031970 | mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970) |
| 0.0 | 0.8 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 0.7 | GO:0042583 | chromaffin granule(GO:0042583) |
| 0.1 | 0.6 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.1 | 0.6 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 1.3 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 1.2 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.0 | 1.2 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 1.1 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.0 | 1.1 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 1.0 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.2 | 0.9 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.2 | 0.9 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 0.0 | 0.9 | GO:0003746 | translation elongation factor activity(GO:0003746) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.9 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 0.8 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.4 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.4 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 0.4 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.3 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.0 | 0.3 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 0.3 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 0.2 | PID ARF 3PATHWAY | Arf1 pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.1 | 0.9 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.1 | 0.7 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 0.7 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 0.5 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.1 | 0.3 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.3 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.0 | 0.3 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 0.3 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.0 | 0.3 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |