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PRJNA207719: Tissue specific transcriptome profiling

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Results for mafb+mafba+nrl

Z-value: 3.51

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Transcription factors associated with mafb+mafba+nrl

Gene Symbol Gene ID Gene Info
ENSDARG00000017121 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
ENSDARG00000076520 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog b (paralog b)
ENSDARG00000100466 neural retina leucine zipper

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nrldr11_v1_chr20_+_661037_6610370.819.9e-02Click!
mafbadr11_v1_chr23_-_3409140_34091400.682.1e-01Click!
mafbdr11_v1_chr25_+_36674715_366747150.335.8e-01Click!

Activity profile of mafb+mafba+nrl motif

Sorted Z-values of mafb+mafba+nrl motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_1291012 4.07 ENSDART00000158390
ATPase plasma membrane Ca2+ transporting 2
chr6_-_60147517 3.66 ENSDART00000083453
solute carrier family 32 (GABA vesicular transporter), member 1
chr8_-_14052349 3.60 ENSDART00000135811
ATPase plasma membrane Ca2+ transporting 3a
chr10_-_7858553 3.18 ENSDART00000182010
inositol polyphosphate-5-phosphatase Ja
chr19_+_233143 3.09 ENSDART00000175273
synaptic Ras GTPase activating protein 1a
chr25_-_3503164 2.84 ENSDART00000191477
ENSDART00000186345
ENSDART00000180199
si:ch211-272n13.7
chr15_+_16897554 2.62 ENSDART00000154679
yippee-like 2b
chr25_-_4482449 2.56 ENSDART00000056278
ENSDART00000149425
solute carrier family 25 member 22a
chr7_-_26087807 2.47 ENSDART00000052989
acetylcholinesterase
chr2_-_44720551 2.31 ENSDART00000146380
MAP6 domain containing 1
chr23_+_45579497 2.27 ENSDART00000110381
early growth response 4
chr9_-_296169 2.18 ENSDART00000165228
kinesin family member 5A, a
chr19_+_37925616 2.18 ENSDART00000148348
neurexophilin 1
chr21_+_41697552 2.14 ENSDART00000169511
protein phosphatase 2, regulatory subunit B, beta b
chr8_+_24854600 2.12 ENSDART00000156570
solute carrier family 6 (neutral amino acid transporter), member 17
chr1_+_36437585 2.07 ENSDART00000189182
POU class 4 homeobox 2
chr1_-_21344478 2.05 ENSDART00000077805
glutamate receptor, ionotropic, AMPA 2a
chr19_-_5254699 2.03 ENSDART00000081951
syntaxin 1B
chr14_+_49135264 2.03 ENSDART00000084119
si:ch1073-44g3.1
chr7_+_72882446 2.00 ENSDART00000131113
ENSDART00000174223
adhesion G protein-coupled receptor L3
chr22_-_38543630 1.99 ENSDART00000172029
si:ch211-126j24.1
chr4_+_26496489 1.99 ENSDART00000160652
IQ motif and Sec7 domain 3a
chr4_+_19534833 1.96 ENSDART00000140028
leucine rich repeat containing 4.1
chr22_+_18816662 1.96 ENSDART00000132476
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr1_+_54673846 1.95 ENSDART00000145018
G protein-coupled receptor, class C, group 5, member Bb
chr6_+_58543336 1.92 ENSDART00000157018
stathmin-like 3
chr13_+_3954540 1.86 ENSDART00000092646
leucine rich repeat containing 73
chr24_-_4973765 1.85 ENSDART00000127597
zic family member 1 (odd-paired homolog, Drosophila)
chr20_-_54462551 1.82 ENSDART00000171769
ENSDART00000169692
Enah/Vasp-like b
chr16_-_44349845 1.81 ENSDART00000170932
regulating synaptic membrane exocytosis 2a
chr25_-_3503458 1.79 ENSDART00000173269
si:ch211-272n13.7
chr2_+_6926100 1.79 ENSDART00000153289
nitric oxide synthase 1 (neuronal) adaptor protein b
chr6_-_24358732 1.78 ENSDART00000159595
epoxide hydrolase 4
chr8_-_23416362 1.77 ENSDART00000063005
G protein-coupled receptor 173
chr19_+_23982466 1.76 ENSDART00000080673
synaptotagmin XIa
chr20_+_88168 1.76 ENSDART00000149283
zgc:112001
chr5_-_12525441 1.76 ENSDART00000177490
ENSDART00000164190
kinase suppressor of ras 2
chr7_-_38612230 1.75 ENSDART00000173678
C1q and TNF related 4
chr2_+_31957554 1.75 ENSDART00000012413
ANKH inorganic pyrophosphate transport regulator b
chr17_-_37214196 1.74 ENSDART00000128715
kinesin family member 3Cb
chr14_+_33458294 1.73 ENSDART00000075278
ATPase Na+/K+ transporting subunit beta 4
chr13_+_3954715 1.73 ENSDART00000182477
ENSDART00000192142
ENSDART00000190962
leucine rich repeat containing 73
chr15_+_2559875 1.72 ENSDART00000178505
SH2B adaptor protein 2
chr7_+_23875269 1.70 ENSDART00000101406
RAB39B, member RAS oncogene family b
chr8_+_29267093 1.68 ENSDART00000077647
glutamate receptor, ionotropic, delta 2
chr14_-_30642819 1.66 ENSDART00000078154
neuronal PAS domain protein 4a
chr23_+_21067684 1.65 ENSDART00000132066
potassium voltage-gated channel, shaker-related subfamily, beta member 2 b
chr13_-_27038407 1.64 ENSDART00000146712
coiled-coil domain containing 85A
chr11_-_3494964 1.64 ENSDART00000162369
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3b
chr5_+_36614196 1.63 ENSDART00000150574
neuro-oncological ventral antigen 1
chr25_+_19999623 1.61 ENSDART00000026401
zgc:194665
chr6_-_13188667 1.60 ENSDART00000191654
ADAM metallopeptidase domain 23a
chr3_-_30118856 1.59 ENSDART00000109953
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr1_+_49266886 1.58 ENSDART00000137179
calcyon neuron-specific vesicular protein
chr23_-_26077038 1.58 ENSDART00000126299
GDP dissociation inhibitor 1
chr21_-_23475361 1.58 ENSDART00000156658
ENSDART00000157454
neural cell adhesion molecule 1a
chr17_+_9310259 1.57 ENSDART00000186158
ENSDART00000190329
neuronal PAS domain protein 3
chr8_+_53464216 1.57 ENSDART00000169514
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr13_+_14006118 1.56 ENSDART00000131875
ENSDART00000089528
attractin
chr24_-_31942656 1.56 ENSDART00000180308
ENSDART00000016879
complement component 1, q subcomponent-like 3a
chr16_-_12984631 1.55 ENSDART00000184863
calcium channel, voltage-dependent, gamma subunit 7b
chr22_+_17359346 1.54 ENSDART00000145434
G protein-coupled receptor 52
chr10_+_1052591 1.51 ENSDART00000123405
unc-5 netrin receptor C
chr5_-_28915130 1.50 ENSDART00000078592
neural proliferation, differentiation and control, 1b
chr17_+_29345606 1.49 ENSDART00000086164
potassium channel tetramerization domain containing 3
chr17_-_12336987 1.48 ENSDART00000172001
synaptosomal-associated protein, 25b
chr22_-_17585618 1.48 ENSDART00000183123
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a
chr1_-_59251874 1.47 ENSDART00000168919
olfactomedin 2b
chr23_-_45049044 1.44 ENSDART00000067630
SH3 domain containing GRB2 like 2, endophilin A1
chr4_+_12113105 1.41 ENSDART00000182399
transmembrane protein 178B
chr13_-_35051897 1.40 ENSDART00000129559
BTB (POZ) domain containing 3b
chr5_-_21030934 1.39 ENSDART00000133461
ENSDART00000098667
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr21_-_45588720 1.39 ENSDART00000186642
ENSDART00000189531

chr14_-_52521460 1.39 ENSDART00000172110
G protein-coupled receptor 151
chr23_-_3674443 1.38 ENSDART00000134830
ENSDART00000057422
protein kinase C and casein kinase substrate in neurons 1a
chr5_-_12524996 1.34 ENSDART00000142258
si:ch73-263f13.1
chr1_-_57280585 1.33 ENSDART00000152220
si:dkey-27j5.5
chr13_-_11644806 1.32 ENSDART00000169953
dynactin 1b
chr4_+_8797197 1.32 ENSDART00000158671
sulfotransferase family 4A, member 1
chr5_+_30624183 1.32 ENSDART00000141444
ATP-binding cassette, sub-family G (WHITE), member 4a
chr12_+_32292564 1.32 ENSDART00000152945
si:ch211-277e21.2
chr23_-_29667544 1.31 ENSDART00000059339
calsyntenin 1
chr7_+_58686860 1.31 ENSDART00000052332
proenkephalin b
chr9_+_49659114 1.29 ENSDART00000189643
cysteine and serine rich nuclear protein 3
chr21_+_42226113 1.29 ENSDART00000170362
gamma-aminobutyric acid type A receptor beta2 subunit
chr4_-_191736 1.29 ENSDART00000169187
ENSDART00000192054
protein tyrosine phosphatase, receptor type, O
chr3_-_19133003 1.28 ENSDART00000145215
glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca
chr23_-_28141419 1.27 ENSDART00000133039
tachykinin 3a
chr9_+_53707240 1.26 ENSDART00000171490
si:ch211-199f5.1
chr2_-_9059955 1.26 ENSDART00000022768
adenylate kinase 5
chr16_+_34528409 1.26 ENSDART00000144718
progestin and adipoQ receptor family member VII, b
chr21_+_26726936 1.25 ENSDART00000065392
calmodulin 2a (phosphorylase kinase, delta)
chr8_+_50983551 1.25 ENSDART00000142061
si:dkey-32e23.4
chr10_+_35953068 1.25 ENSDART00000015279
reticulon 4 receptor-like 1a
chr12_-_11570 1.24 ENSDART00000186179
shisa family member 6
chr5_-_22501663 1.24 ENSDART00000133174
si:dkey-27p18.5
chr6_-_10776254 1.23 ENSDART00000184008
G protein-coupled receptor 155b
chr3_+_14317802 1.23 ENSDART00000162023
phospholipid phosphatase related 2a
chr18_+_14477740 1.23 ENSDART00000146472
potassium voltage-gated channel, subfamily G, member 4a
chr14_-_2050057 1.22 ENSDART00000112875
protocadherin beta 15
chr20_-_40717900 1.22 ENSDART00000181663
connexin 43
chr6_+_59642695 1.21 ENSDART00000166373
ENSDART00000161030
R3H domain containing 2
chr9_-_44295071 1.21 ENSDART00000011837
neuronal differentiation 1
chr20_+_52389858 1.20 ENSDART00000185863
ENSDART00000166651
Rho GTPase activating protein 39
chr10_+_44641599 1.20 ENSDART00000172128
seizure related 6 homolog (mouse)-like
chr5_-_70625697 1.20 ENSDART00000179538
ENSDART00000190540

chr20_-_37629084 1.20 ENSDART00000141734
human immunodeficiency virus type I enhancer binding protein 2a
chr19_-_27261102 1.19 ENSDART00000143919
gamma-aminobutyric acid (GABA) B receptor, 1b
chr20_+_48803248 1.19 ENSDART00000164006
NK2 homeobox 4b
chr23_-_7799184 1.19 ENSDART00000190946
ENSDART00000165427
myelin transcription factor 1b
chr7_-_24699985 1.19 ENSDART00000052802
calbindin 2b
chr5_+_45976130 1.19 ENSDART00000175670
synaptic vesicle glycoprotein 2C
chr19_-_10081047 1.19 ENSDART00000128837
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a
chr18_-_85294 1.18 ENSDART00000044387
GA binding protein transcription factor, beta subunit 1
chr4_-_21851473 1.18 ENSDART00000019748
lin-7 homolog A (C. elegans)
chr12_-_29624638 1.18 ENSDART00000126744
neuregulin 3b
chr22_+_635813 1.18 ENSDART00000179067

chr17_-_12385308 1.18 ENSDART00000080927
synaptosomal-associated protein, 25b
chr2_-_24444838 1.18 ENSDART00000147885
ENSDART00000164720
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1a
chr24_-_29997145 1.17 ENSDART00000135094
palmdelphin b
chr20_+_54383838 1.17 ENSDART00000157737
leucine rich repeat and fibronectin type III domain containing 5b
chr12_-_45533034 1.17 ENSDART00000113004

chr5_+_57743815 1.17 ENSDART00000005090
ALG9, alpha-1,2-mannosyltransferase
chr4_-_27350820 1.16 ENSDART00000145806
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5a
chr21_-_31143903 1.16 ENSDART00000111571
RAP1 GTPase activating protein 2b
chr20_-_34801181 1.16 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr23_-_11870962 1.15 ENSDART00000143481
si:dkey-178k16.1
chr10_+_16188761 1.14 ENSDART00000193244
cortexin 3
chr18_-_1228688 1.14 ENSDART00000064403
neuroplastin b
chr2_-_58193381 1.14 ENSDART00000159040
purine nucleoside phosphorylase 5b
chr23_-_14990865 1.13 ENSDART00000147799
ndrg family member 3b
chr11_+_30161168 1.13 ENSDART00000157385
cyclin-dependent kinase-like 5
chr8_-_4596662 1.13 ENSDART00000138199
septin 5a
chr6_-_58828398 1.12 ENSDART00000090634
kinesin family member 5A, b
chr22_-_600016 1.12 ENSDART00000086434
transmembrane and coiled-coil domain family 2
chr5_+_20148671 1.11 ENSDART00000143205
SV2 related protein a
chr23_-_44494401 1.11 ENSDART00000114640
ENSDART00000148532
actin-like 6B
chr23_+_25210953 1.11 ENSDART00000132799
si:dkey-151g10.3
chr24_+_39129316 1.09 ENSDART00000155346
TBC1 domain family, member 24
chr19_-_9882821 1.09 ENSDART00000147128
calcium channel, voltage-dependent, gamma subunit 7a
chr19_-_9712530 1.08 ENSDART00000134816
solute carrier family 2 (facilitated glucose transporter), member 3a
chr16_-_6424816 1.08 ENSDART00000164864
ENSDART00000141860
membrane bound O-acyltransferase domain containing 1
chr10_+_39164638 1.08 ENSDART00000188997

chr2_+_47623202 1.07 ENSDART00000154465
si:ch211-165b10.3
chr24_-_35707552 1.07 ENSDART00000165199
microtubule-associated protein, RP/EB family, member 2
chr23_+_2560005 1.07 ENSDART00000186906
gamma-glutamyltransferase 7
chr3_-_18711288 1.06 ENSDART00000183885
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a
chr25_-_12906872 1.06 ENSDART00000165156
ENSDART00000167449
septin 15
chr17_-_43286903 1.06 ENSDART00000176637
si:dkey-1f12.3
chr14_-_2206476 1.06 ENSDART00000081870
protocadherin 2 alpha b 6
chr19_+_32947910 1.05 ENSDART00000052091
ATPase H+ transporting V1 subunit C1b
chr8_+_1082100 1.05 ENSDART00000149276
leucine zipper, putative tumor suppressor family member 3b
chr1_+_7679328 1.05 ENSDART00000163488
ENSDART00000190070
engrailed homeobox 1b
chr12_-_3840664 1.05 ENSDART00000160967
TAO kinase 2b
chr4_-_8882572 1.04 ENSDART00000190060
metallophosphoesterase domain containing 1
chr8_+_53423408 1.04 ENSDART00000164792
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr6_+_41255485 1.04 ENSDART00000042683
ENSDART00000186013
Ca2+-dependent activator protein for secretion b
chr9_-_41323746 1.04 ENSDART00000140564
glutaminase b
chr9_-_23217196 1.03 ENSDART00000083567
kinesin family member 5C
chr13_+_15657911 1.02 ENSDART00000134972
ENSDART00000138991
ENSDART00000133342
MAP/microtubule affinity-regulating kinase 3a
chr1_+_29281764 1.01 ENSDART00000112106
family with sequence similarity 155, member A
chr15_-_10341048 1.01 ENSDART00000171013
teneurin transmembrane protein 4
chr20_-_31905968 1.01 ENSDART00000142806
syntaxin binding protein 5a (tomosyn)
chr14_+_1365097 1.01 ENSDART00000083797
ENSDART00000176087
TBC1 domain family, member 9 (with GRAM domain)
chr12_+_42574148 1.01 ENSDART00000157855
early B cell factor 3a
chr5_+_71999996 1.01 ENSDART00000179933
ENSDART00000187070
phospholipid phosphatase 7 (inactive)
chr22_-_22416337 1.00 ENSDART00000142947
ENSDART00000089569
calmodulin regulated spectrin-associated protein family, member 2a
chr4_+_23223881 1.00 ENSDART00000133056
ENSDART00000089126
thyrotropin releasing hormone degrading enzyme, tandem duplicate 1
chr9_-_327901 1.00 ENSDART00000159956
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2a
chr12_-_26383242 1.00 ENSDART00000152941
ubiquitin specific peptidase 54b
chr8_+_25254435 0.99 ENSDART00000143554
adenosine monophosphate deaminase 2b
chr1_-_20271138 0.99 ENSDART00000185931
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr15_-_19771981 0.99 ENSDART00000175502
ENSDART00000159475
phosphatidylinositol binding clathrin assembly protein b
chr1_+_29858032 0.99 ENSDART00000054066
zic family member 2 (odd-paired homolog, Drosophila) b
chr19_+_33093395 0.99 ENSDART00000019459
family with sequence similarity 91, member A1
chr1_+_59154521 0.98 ENSDART00000130089
ENSDART00000152456
heme-binding protein soul5, like
chr1_+_38758261 0.98 ENSDART00000182756
WD repeat domain 17
chr2_-_56635744 0.98 ENSDART00000167790
ENSDART00000168160
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b
chr15_+_46386261 0.98 ENSDART00000191793
immunoglobulin superfamily member 11
chr3_+_20156956 0.98 ENSDART00000125281
nerve growth factor receptor a (TNFR superfamily, member 16)
chr20_-_20931197 0.97 ENSDART00000152726
BTB (POZ) domain containing 6b
chr18_+_22793465 0.97 ENSDART00000149685
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a
chr8_+_54055390 0.97 ENSDART00000102696
membrane associated guanylate kinase, WW and PDZ domain containing 1a
chr17_-_7861219 0.97 ENSDART00000148604
spectrin repeat containing, nuclear envelope 1b
chr5_+_36415978 0.96 ENSDART00000084464
family with sequence similarity 155, member B
chr15_+_24212847 0.96 ENSDART00000155502
seizure related 6 homolog b
chr7_-_38477235 0.96 ENSDART00000084355
zgc:165481
chr4_-_19028861 0.96 ENSDART00000166374
si:dkey-31f5.11
chr6_-_43092175 0.95 ENSDART00000084389
leucine rich repeat neuronal 1
chr19_+_33093577 0.94 ENSDART00000180317
family with sequence similarity 91, member A1
chr18_+_30028135 0.94 ENSDART00000140825
ENSDART00000145306
ENSDART00000136810
si:ch211-220f16.1
chr24_+_24461558 0.94 ENSDART00000182424
basic helix-loop-helix family, member e22
chr4_+_11439511 0.94 ENSDART00000150485
piccolo presynaptic cytomatrix protein a
chr3_-_35801146 0.94 ENSDART00000150911
CASK interacting protein 1
chr18_+_38908903 0.94 ENSDART00000159834
myosin VAa
chr4_+_4816695 0.93 ENSDART00000136962
solute carrier family 13 (sodium/sulfate symporter), member 4
chr20_-_53321499 0.93 ENSDART00000179894
ENSDART00000127427
ENSDART00000084952
WAS protein family, member 1
chr25_+_35706493 0.93 ENSDART00000176741
kinesin family member 21A
chr9_+_30890549 0.93 ENSDART00000101070
dachshund d
chr12_-_4672708 0.92 ENSDART00000152659
ENSDART00000186076
si:ch211-255p10.4

Network of associatons between targets according to the STRING database.

First level regulatory network of mafb+mafba+nrl

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0015824 proline transport(GO:0015824)
0.6 4.3 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.6 2.5 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.5 1.6 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.5 1.4 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.5 3.7 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.4 2.0 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.4 3.0 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.3 1.0 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.3 1.7 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.3 1.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 1.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.3 1.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.3 1.2 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.3 0.9 GO:0036314 response to sterol(GO:0036314) cellular response to sterol(GO:0036315) SREBP-SCAP complex retention in endoplasmic reticulum(GO:0036316) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.3 0.9 GO:0015874 norepinephrine transport(GO:0015874)
0.3 0.8 GO:1903792 negative regulation of anion transport(GO:1903792)
0.3 2.0 GO:1903306 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.3 1.7 GO:0051969 regulation of transmission of nerve impulse(GO:0051969)
0.3 1.8 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.3 0.8 GO:0031645 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.3 0.8 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.3 2.6 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.3 1.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 1.3 GO:1903146 regulation of mitophagy(GO:1903146)
0.2 1.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 2.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 0.8 GO:0044003 modification by symbiont of host morphology or physiology(GO:0044003) modulation by symbiont of host cellular process(GO:0044068)
0.2 1.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.2 1.3 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.2 2.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.7 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.2 0.9 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.2 2.6 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 0.7 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.7 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1 1.0 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 1.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.5 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 2.5 GO:0099565 excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
0.1 0.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.0 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 0.4 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1 2.5 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 1.1 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.1 1.0 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 2.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.0 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 0.5 GO:1902260 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 1.1 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 1.1 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 0.3 GO:2000405 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.1 1.5 GO:0048899 anterior lateral line development(GO:0048899)
0.1 0.9 GO:0043584 nose development(GO:0043584)
0.1 0.6 GO:0010586 miRNA metabolic process(GO:0010586)
0.1 1.9 GO:0048923 posterior lateral line neuromast hair cell differentiation(GO:0048923)
0.1 0.5 GO:0035608 protein deglutamylation(GO:0035608)
0.1 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 1.5 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.7 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.3 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 1.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 0.3 GO:0035992 tendon formation(GO:0035992)
0.1 0.5 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.3 GO:0060148 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1 1.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.3 GO:0046087 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.1 0.6 GO:1903400 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.1 3.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.9 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.1 0.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.9 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 1.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 2.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.4 GO:0055071 manganese ion homeostasis(GO:0055071)
0.1 1.5 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.1 0.4 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.1 0.2 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.1 1.1 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.4 GO:0046677 response to antibiotic(GO:0046677)
0.1 3.8 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.1 0.7 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.3 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 0.4 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 1.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.3 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659) negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 3.0 GO:0072114 pronephros morphogenesis(GO:0072114)
0.1 0.2 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.1 1.0 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.5 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.3 GO:0006844 acyl carnitine transport(GO:0006844)
0.1 0.6 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 0.9 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1 1.7 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 3.3 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 1.2 GO:0030878 thyroid gland development(GO:0030878)
0.1 0.8 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 2.7 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 1.0 GO:0032264 IMP salvage(GO:0032264)
0.1 1.2 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 0.6 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.1 0.5 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 0.3 GO:0009098 leucine biosynthetic process(GO:0009098)
0.1 1.8 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 1.3 GO:0001556 oocyte maturation(GO:0001556)
0.1 0.7 GO:0030431 sleep(GO:0030431)
0.1 1.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.3 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.1 0.4 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.1 1.0 GO:0097324 melanocyte migration(GO:0097324)
0.1 0.4 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 0.2 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 1.3 GO:0043967 histone H4 acetylation(GO:0043967)
0.1 11.6 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 0.6 GO:0043901 negative regulation of multi-organism process(GO:0043901)
0.1 0.4 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 0.7 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 1.3 GO:0051289 protein homotetramerization(GO:0051289)
0.1 0.5 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.4 GO:0035188 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.2 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 0.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 1.0 GO:0008354 germ cell migration(GO:0008354)
0.1 1.5 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0035376 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.2 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.0 0.6 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.4 GO:0072425 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.0 0.9 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 1.1 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 4.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.3 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.0 0.9 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.2 GO:0048387 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0021767 mammillary body development(GO:0021767)
0.0 1.2 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.7 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.2 GO:1903729 regulation of plasma membrane organization(GO:1903729)
0.0 0.8 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 6.1 GO:0006814 sodium ion transport(GO:0006814)
0.0 1.4 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 1.1 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.0 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.9 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.5 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.9 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.9 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.4 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.5 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.2 GO:0035094 response to nicotine(GO:0035094)
0.0 0.3 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.1 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.6 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 1.0 GO:0030901 midbrain development(GO:0030901)
0.0 0.8 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.5 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.8 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.2 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902229)
0.0 0.3 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.4 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.7 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.3 GO:0061709 reticulophagy(GO:0061709)
0.0 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.0 0.0 GO:1903589 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.0 1.4 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0015886 heme transport(GO:0015886) iron coordination entity transport(GO:1901678)
0.0 0.3 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.8 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 2.0 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.2 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0 0.7 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 3.2 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 0.9 GO:1903844 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 0.6 GO:0050890 cognition(GO:0050890)
0.0 0.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.7 GO:0050868 negative regulation of homotypic cell-cell adhesion(GO:0034111) negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 1.7 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.1 GO:0007269 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 1.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 1.4 GO:0017157 regulation of exocytosis(GO:0017157)
0.0 1.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.8 GO:0046058 cAMP biosynthetic process(GO:0006171) cAMP metabolic process(GO:0046058)
0.0 1.0 GO:0016573 histone acetylation(GO:0016573)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.3 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.4 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 4.4 GO:0043087 regulation of GTPase activity(GO:0043087)
0.0 0.6 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.6 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.1 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.0 1.6 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.2 GO:0036065 fucosylation(GO:0036065)
0.0 0.3 GO:0043486 histone exchange(GO:0043486)
0.0 0.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.5 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.1 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.4 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0072318 clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.0 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.4 GO:0001878 response to yeast(GO:0001878)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.5 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.5 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.2 GO:0060021 palate development(GO:0060021)
0.0 0.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.0 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.3 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.6 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.1 GO:0072554 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.0 0.0 GO:0061614 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.2 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.1 GO:0042138 meiotic DNA double-strand break processing(GO:0000706) meiotic DNA double-strand break formation(GO:0042138)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.4 1.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 1.9 GO:0070062 extracellular exosome(GO:0070062)
0.3 1.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.3 0.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 3.7 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 0.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 9.9 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.2 0.7 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 1.7 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.2 2.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.2 0.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 1.2 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1 0.4 GO:1990745 EARP complex(GO:1990745)
0.1 1.2 GO:0036449 microtubule minus-end(GO:0036449)
0.1 3.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 1.3 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 1.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.9 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0000938 GARP complex(GO:0000938)
0.1 2.8 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.1 0.5 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 2.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 6.9 GO:0005871 kinesin complex(GO:0005871)
0.1 0.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 1.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.6 GO:0016586 RSC complex(GO:0016586)
0.1 0.3 GO:0070209 ASTRA complex(GO:0070209)
0.1 1.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 1.2 GO:0043195 terminal bouton(GO:0043195)
0.1 1.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.2 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.4 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 3.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 0.2 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 4.5 GO:0001726 ruffle(GO:0001726)
0.1 1.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.1 GO:0031256 leading edge membrane(GO:0031256)
0.0 0.3 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.6 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.4 GO:0070552 BRISC complex(GO:0070552)
0.0 2.4 GO:0030426 growth cone(GO:0030426)
0.0 0.9 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0044306 neuron projection terminus(GO:0044306)
0.0 2.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.5 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 1.6 GO:0030496 midbody(GO:0030496)
0.0 5.6 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.9 GO:0000145 exocyst(GO:0000145)
0.0 2.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0070449 elongin complex(GO:0070449)
0.0 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 1.0 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 4.8 GO:0045202 synapse(GO:0045202)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 2.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 2.0 GO:0030141 secretory granule(GO:0030141)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.4 GO:0043209 myelin sheath(GO:0043209)
0.0 1.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.8 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 2.7 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.3 GO:0044545 NSL complex(GO:0044545)
0.0 0.2 GO:0030130 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 2.2 GO:0034703 cation channel complex(GO:0034703)
0.0 2.1 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.3 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.0 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.4 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.1 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 8.1 GO:0043005 neuron projection(GO:0043005)
0.0 0.5 GO:0036452 ESCRT complex(GO:0036452)
0.0 0.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.6 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 0.3 GO:0005921 gap junction(GO:0005921)
0.0 3.3 GO:0005768 endosome(GO:0005768)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.0 GO:1990130 Iml1 complex(GO:1990130)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.5 1.4 GO:0047325 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726)
0.4 2.5 GO:0004104 cholinesterase activity(GO:0004104)
0.4 3.0 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.4 1.8 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.3 1.7 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.3 1.8 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.3 1.2 GO:0097016 L27 domain binding(GO:0097016)
0.3 0.9 GO:0005333 dopamine transmembrane transporter activity(GO:0005329) dopamine:sodium symporter activity(GO:0005330) norepinephrine transmembrane transporter activity(GO:0005333) norepinephrine:sodium symporter activity(GO:0005334)
0.3 3.7 GO:0015295 solute:proton symporter activity(GO:0015295)
0.3 3.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.3 8.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.3 0.8 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 1.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.2 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 1.8 GO:0005522 profilin binding(GO:0005522)
0.2 1.3 GO:0031628 opioid receptor binding(GO:0031628)
0.2 0.5 GO:0043621 protein self-association(GO:0043621)
0.2 0.5 GO:0046978 TAP1 binding(GO:0046978)
0.2 8.6 GO:0044325 ion channel binding(GO:0044325)
0.2 1.5 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 1.0 GO:0005035 death receptor activity(GO:0005035)
0.1 1.2 GO:0030507 spectrin binding(GO:0030507)
0.1 2.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 1.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.9 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.1 1.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 2.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.7 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.0 GO:0004359 glutaminase activity(GO:0004359)
0.1 1.6 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.9 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.6 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.5 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.1 0.5 GO:0015288 porin activity(GO:0015288)
0.1 0.7 GO:0099583 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 1.7 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.1 0.5 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 1.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 1.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.5 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.6 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.3 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.7 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 2.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.0 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.6 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 3.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.3 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.1 0.5 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 2.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.1 0.9 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 1.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 1.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.3 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 2.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.5 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 2.0 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.5 GO:0008494 translation activator activity(GO:0008494)
0.1 0.4 GO:0001006 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 0.9 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.8 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.2 GO:0070404 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404)
0.1 0.8 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 2.6 GO:0016247 channel regulator activity(GO:0016247)
0.0 1.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.1 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 1.0 GO:0043236 laminin binding(GO:0043236)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.8 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 3.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.6 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 1.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.7 GO:0030552 cAMP binding(GO:0030552)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.7 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.7 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.6 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 1.9 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.8 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.8 GO:0031267 small GTPase binding(GO:0031267)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.5 GO:0045159 myosin II binding(GO:0045159)
0.0 1.0 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.3 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.8 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 1.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.7 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 8.2 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.8 GO:0004890 GABA-A receptor activity(GO:0004890) GABA receptor activity(GO:0016917)
0.0 1.8 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.5 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 1.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 2.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.9 GO:0000146 microfilament motor activity(GO:0000146) actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.0 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.0 GO:0047453 ATP-dependent NAD(P)H-hydrate dehydratase activity(GO:0047453) ADP-dependent NAD(P)H-hydrate dehydratase activity(GO:0052855)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.3 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.8 GO:0071949 FAD binding(GO:0071949)
0.0 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 2.4 GO:0015293 symporter activity(GO:0015293)
0.0 0.0 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.9 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 3.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 3.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 2.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 0.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 1.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.0 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 2.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.1 PID INSULIN PATHWAY Insulin Pathway
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.6 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.6 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.3 4.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.3 3.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.3 5.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 1.1 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.2 3.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 2.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 0.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 1.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.6 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import