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PRJNA207719: Tissue specific transcriptome profiling

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Results for lmx1ba+lmx1bb_lmx1al

Z-value: 0.86

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Transcription factors associated with lmx1ba+lmx1bb_lmx1al

Gene Symbol Gene ID Gene Info
ENSDARG00000068365 LIM homeobox transcription factor 1, beta b
ENSDARG00000104815 LIM homeobox transcription factor 1, beta a
ENSDARG00000077915 LIM homeobox transcription factor 1, alpha-like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lmx1aldr11_v1_chr3_+_52806347_52806441-0.573.2e-01Click!
lmx1bbdr11_v1_chr8_-_33381913_333819130.405.0e-01Click!
lmx1badr11_v1_chr5_-_5147220_5147336-0.365.5e-01Click!

Activity profile of lmx1ba+lmx1bb_lmx1al motif

Sorted Z-values of lmx1ba+lmx1bb_lmx1al motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_23431189 1.04 ENSDART00000004679
ictacalcin
chr21_+_25777425 0.99 ENSDART00000021620
claudin d
chr10_-_21362071 0.82 ENSDART00000125167
avidin
chr23_-_31913231 0.80 ENSDART00000146852
ENSDART00000085054
mitochondrial fission regulator 2
chr10_-_21362320 0.67 ENSDART00000189789
avidin
chr16_-_29387215 0.67 ENSDART00000148787
S100 calcium binding protein A1
chr8_+_21353878 0.61 ENSDART00000056420
aminolevulinate, delta-, synthase 2
chr7_+_20503344 0.61 ENSDART00000157699
si:dkey-19b23.12
chr17_+_28103675 0.59 ENSDART00000188078
zgc:91908
chr12_-_35830625 0.59 ENSDART00000180028

chr6_+_41191482 0.58 ENSDART00000000877
opsin 1 (cone pigments), medium-wave-sensitive, 3
chr25_+_31276842 0.58 ENSDART00000187238
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr24_-_35561672 0.57 ENSDART00000058564
minichromosome maintenance complex component 4
chr1_-_18811517 0.56 ENSDART00000142026
si:dkey-167i21.2
chr24_-_2450597 0.56 ENSDART00000188080
ENSDART00000093331
ras responsive element binding protein 1a
chr9_+_8396755 0.56 ENSDART00000043067
zgc:171776
chr13_-_31017960 0.52 ENSDART00000145287
WDFY family member 4
chr23_-_31913069 0.51 ENSDART00000135526
mitochondrial fission regulator 2
chr16_+_29509133 0.50 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr23_+_11285662 0.49 ENSDART00000111028
cell adhesion molecule L1-like a
chr22_+_7439186 0.46 ENSDART00000190667
zgc:92041
chr22_+_1170294 0.45 ENSDART00000159761
ENSDART00000169809
interferon regulatory factor 6
chr22_+_19552987 0.45 ENSDART00000105315
hydroxysteroid (11-beta) dehydrogenase 1-like a
chr1_+_45056371 0.44 ENSDART00000073689
ENSDART00000167309
bloodthirsty-related gene family, member 1
chr18_+_20560442 0.44 ENSDART00000151990
WEE1 homolog 2 (S. pombe)
chr22_-_17653143 0.43 ENSDART00000089171
histocompatibility (minor) HA-1 b
chr22_-_17652914 0.43 ENSDART00000138483
si:ch73-243b8.4
chr8_-_20230559 0.42 ENSDART00000193677
MLLT1, super elongation complex subunit a
chr8_-_14126646 0.40 ENSDART00000027225
biglycan a
chr20_-_40755614 0.40 ENSDART00000061247
connexin 32.3
chr18_+_19456648 0.39 ENSDART00000079695
zwilch kinetochore protein
chr18_+_15644559 0.39 ENSDART00000061794
nuclear receptor subfamily 1, group H, member 4
chr3_-_61162750 0.39 ENSDART00000055064
parvalbumin 8
chr8_+_6576940 0.39 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr16_-_16761164 0.39 ENSDART00000135872
si:dkey-27n14.1
chr13_+_24750078 0.38 ENSDART00000021053
collagen, type XVII, alpha 1b
chr19_+_43297546 0.38 ENSDART00000168002
lysosomal protein transmembrane 5
chr1_-_43905252 0.38 ENSDART00000135477
ENSDART00000132089
si:dkey-22i16.3
chr1_+_44173245 0.37 ENSDART00000159450
ENSDART00000106048
ENSDART00000157763
catenin (cadherin-associated protein), delta 1
chr5_+_6954162 0.36 ENSDART00000086666
sperm-tail PG-rich repeat containing 2
chr8_+_45334255 0.36 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
poly(A) binding protein, cytoplasmic 1-like
chr14_-_22113600 0.36 ENSDART00000113752
si:dkey-6i22.5
chr3_-_16719244 0.35 ENSDART00000055859
polymerase (DNA directed), delta 1, catalytic subunit
chr20_-_23426339 0.35 ENSDART00000004625
zygote arrest 1
chr22_+_19220459 0.35 ENSDART00000163070
si:dkey-21e2.7
chr25_-_3867990 0.35 ENSDART00000075663
calcium release activated channel regulator 2B
chr11_-_44801968 0.35 ENSDART00000161846
microtubule-associated protein 1 light chain 3 gamma
chr2_-_26596794 0.34 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr18_-_19456269 0.34 ENSDART00000060363
ribosomal protein L4
chr16_+_23961276 0.34 ENSDART00000192754
apolipoprotein Eb
chr18_+_3037998 0.34 ENSDART00000185844
ENSDART00000162657
ribosomal protein S3
chr1_-_10821584 0.34 ENSDART00000167452
ENSDART00000162137
cytokine receptor family member B15
chr8_+_11425048 0.33 ENSDART00000018739
tight junction protein 2b (zona occludens 2)
chr23_+_31913292 0.33 ENSDART00000136910
armadillo repeat containing 1, like
chr25_+_18475032 0.32 ENSDART00000073564
testis derived transcript (3 LIM domains)
chr15_-_21877726 0.32 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
chr6_-_43283122 0.31 ENSDART00000186022
FERM domain containing 4Ba
chr1_+_9966384 0.31 ENSDART00000132607
si:dkeyp-75b4.8
chr19_+_2631565 0.31 ENSDART00000171487
family with sequence similarity 126, member A
chr24_-_6078222 0.31 ENSDART00000146830
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr8_-_25034411 0.30 ENSDART00000135973
nuclear transcription factor Y, alpha, like
chr3_-_50443607 0.29 ENSDART00000074036
recoverin a
chr2_+_33326522 0.29 ENSDART00000056655
Kruppel-like factor 17
chr20_-_43663494 0.29 ENSDART00000144564

chr15_+_31344472 0.29 ENSDART00000146695
ENSDART00000159182
ENSDART00000060125
odorant receptor, family D, subfamily 107, member 1
chr2_+_30032303 0.28 ENSDART00000151841
RNA binding motif protein 33b
chr5_+_66433287 0.28 ENSDART00000170757
kinetochore associated 1
chr16_-_51299061 0.28 ENSDART00000148677
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4
chr18_+_20560616 0.28 ENSDART00000136710
ENSDART00000151974
ENSDART00000121699
ENSDART00000040074
WEE1 homolog 2 (S. pombe)
chr23_+_39695827 0.28 ENSDART00000113893
ENSDART00000186679
transmembrane and coiled-coil domains 4
chr17_+_25481466 0.27 ENSDART00000139451
crystallin beta-gamma domain containing 1a
chr13_-_45155792 0.27 ENSDART00000163556
runt-related transcription factor 3
chr16_+_33902006 0.27 ENSDART00000161807
ENSDART00000159474
guanine nucleotide binding protein-like 2 (nucleolar)
chr23_-_17003533 0.27 ENSDART00000080545
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr10_-_25217347 0.27 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr20_-_52902693 0.27 ENSDART00000166115
ENSDART00000161050
cathepsin Bb
chr7_+_7048245 0.27 ENSDART00000001649
actinin alpha 3b
chr15_+_36457888 0.27 ENSDART00000155100
si:dkey-262k9.2
chr2_+_37227011 0.26 ENSDART00000126587
ENSDART00000084958
sterile alpha motif domain containing 7
chr16_+_26777473 0.26 ENSDART00000188870
cadherin 17, LI cadherin (liver-intestine)
chr22_-_15578402 0.26 ENSDART00000062986
hematopoietic SH2 domain containing
chr1_-_5455498 0.25 ENSDART00000040368
ENSDART00000114035
motor neuron and pancreas homeobox 2b
chr7_-_71389375 0.25 ENSDART00000128928

chr10_-_15340362 0.25 ENSDART00000148119
ENSDART00000127277
ENSDART00000154037
ENSDART00000189109
pumilio RNA-binding family member 3
chr24_-_27452488 0.25 ENSDART00000136433
chemokine (C-C motif) ligand 34b, duplicate 8
chr17_+_16090436 0.24 ENSDART00000136059
ENSDART00000138734
zinc finger protein 395a
chr10_+_8885769 0.24 ENSDART00000139466
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2
chr24_-_38110779 0.24 ENSDART00000147783
c-reactive protein, pentraxin-related
chr9_-_50001606 0.23 ENSDART00000161648
ENSDART00000168514
sodium channel, voltage-gated, type I, alpha
chr11_+_35050253 0.23 ENSDART00000124800
family with sequence similarity 212, member Aa
chr25_-_21031007 0.23 ENSDART00000138985
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr2_+_19522082 0.23 ENSDART00000146098
Pim proto-oncogene, serine/threonine kinase, related 49
chr25_+_13620555 0.23 ENSDART00000163642
si:ch211-172l8.4
chr7_+_20471315 0.23 ENSDART00000173714
si:dkey-19b23.13
chr5_+_36850650 0.22 ENSDART00000051186
non-specific cytotoxic cell receptor protein 1
chr3_-_32337653 0.22 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
chr8_-_23612462 0.22 ENSDART00000025024
solute carrier family 38, member 5b
chr3_+_46635527 0.22 ENSDART00000153971
si:dkey-248g21.1
chr13_+_27232848 0.22 ENSDART00000138043
Ras and Rab interactor 2
chr3_-_15081874 0.22 ENSDART00000192532
NME/NM23 nucleoside diphosphate kinase 4
chr8_+_30112655 0.22 ENSDART00000099027
Fanconi anemia, complementation group C
chr10_+_6884627 0.22 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr16_+_23913943 0.22 ENSDART00000175404
ENSDART00000129525
apolipoprotein A-IV b, tandem duplicate 1
chr8_-_20230802 0.21 ENSDART00000063400
MLLT1, super elongation complex subunit a
chr11_-_1550709 0.21 ENSDART00000110097
si:ch73-303b9.1
chr6_+_39098397 0.21 ENSDART00000003716
ENSDART00000188655
protease, serine, 60.2
chr7_+_2236317 0.21 ENSDART00000075859
zgc:172065
chr14_+_22113331 0.20 ENSDART00000109759
thioredoxin-related transmembrane protein 2a
chr5_-_7199998 0.20 ENSDART00000167316

chr4_-_9891874 0.20 ENSDART00000067193
adrenomedullin 2a
chr17_-_26867725 0.20 ENSDART00000153590
si:dkey-221l4.10
chr13_+_28747934 0.20 ENSDART00000160176
ENSDART00000101633
ENSDART00000136318
prominin 2
chr3_-_36210344 0.20 ENSDART00000025326
casein kinase 1, delta a
chr1_-_10071422 0.20 ENSDART00000135522
ENSDART00000033118
fibrinogen alpha chain
chr14_+_35428152 0.20 ENSDART00000172597
synaptotagmin-like 4
chr9_-_9415000 0.19 ENSDART00000146210
si:ch211-214p13.9
chr20_-_37813863 0.19 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr17_-_2690083 0.19 ENSDART00000135374
protein tyrosine phosphatase, non-receptor type 21
chr10_-_34916208 0.19 ENSDART00000187371
cyclin A1
chr16_-_42056137 0.19 ENSDART00000102798
zona pellucida glycoprotein 3d tandem duplicate 2
chr11_-_45138857 0.19 ENSDART00000166501
calcium activated nucleotidase 1b
chr20_-_6532462 0.19 ENSDART00000054653
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like
chr18_-_40708537 0.19 ENSDART00000077577
si:ch211-132b12.8
chr19_+_43119014 0.19 ENSDART00000023156
eukaryotic translation elongation factor 1 alpha 1, like 1
chr23_-_31974060 0.18 ENSDART00000168087

chr8_+_23152244 0.18 ENSDART00000036801
ENSDART00000184298
solute carrier family 17 (vesicular nucleotide transporter), member 9a
chr3_+_1637358 0.18 ENSDART00000180266

chr11_-_41853874 0.18 ENSDART00000002556
MRT4 homolog, ribosome maturation factor
chr24_+_12835935 0.18 ENSDART00000114762
nanog homeobox
chr10_-_8053753 0.18 ENSDART00000162289
si:ch211-251f6.7
chr2_+_3201345 0.18 ENSDART00000130349
wingless-type MMTV integration site family, member 9A
chr15_-_43284021 0.18 ENSDART00000041677
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr5_+_33519943 0.18 ENSDART00000131316
membrane-spanning 4-domains, subfamily A, member 17C.1
chr13_+_25449681 0.17 ENSDART00000101328
atonal bHLH transcription factor 7
chr7_+_56577522 0.17 ENSDART00000149130
ENSDART00000149624
haptoglobin
chr2_+_19633493 0.17 ENSDART00000147989
Pim proto-oncogene, serine/threonine kinase, related 54
chr24_+_19415124 0.17 ENSDART00000186931
sulfatase 1
chr3_+_27798094 0.17 ENSDART00000075100
ENSDART00000151437
calcium regulated heat stable protein 1
chr23_-_16485190 0.17 ENSDART00000155038
si:dkeyp-100a5.4
chr8_-_44378391 0.17 ENSDART00000158784
ENSDART00000098138
si:busm1-228j01.6
chr23_+_2728095 0.17 ENSDART00000066086
zgc:114123
chr15_-_2493771 0.17 ENSDART00000184906
sialidase 4
chr18_+_7073130 0.17 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
chr15_+_6109861 0.16 ENSDART00000185154
Purkinje cell protein 4
chr22_-_10121880 0.16 ENSDART00000002348
retinol dehydrogenase 5 (11-cis/9-cis)
chr10_+_21867307 0.16 ENSDART00000126629
cerebellin 17
chr20_+_46492175 0.16 ENSDART00000060695
zinc finger CCCH-type containing 14
chr10_+_29850330 0.16 ENSDART00000168898
heat shock protein 8
chr19_-_5699703 0.15 ENSDART00000082050
zgc:174904
chr22_-_13042992 0.15 ENSDART00000028787
aryl hydrocarbon receptor 1b
chr7_+_25033924 0.15 ENSDART00000170873
sb:cb1058
chr24_-_40744672 0.15 ENSDART00000160672

chr12_+_48803098 0.15 ENSDART00000074768
peptidylprolyl isomerase Fb
chr7_-_31321027 0.15 ENSDART00000186878

chr2_+_36112273 0.14 ENSDART00000191315
T-cell receptor alpha joining 35
chr13_-_31008275 0.14 ENSDART00000139394
WDFY family member 4
chr25_-_18435481 0.14 ENSDART00000004771
POC1 centriolar protein B
chr8_+_25034544 0.14 ENSDART00000123300
neugrin, neurite outgrowth associated
chr23_+_36122058 0.14 ENSDART00000184448
homeobox C3a
chr16_-_38118003 0.14 ENSDART00000058667
si:dkey-23o4.6
chr16_-_38609146 0.14 ENSDART00000144651
eukaryotic translation initiation factor 3, subunit E, a
chr20_+_11731039 0.14 ENSDART00000152215
ENSDART00000152585
si:ch211-155o21.3
chr19_+_7152966 0.14 ENSDART00000080348
bromodomain containing 2a
chr17_-_24575893 0.14 ENSDART00000141914
aftiphilin b
chr6_-_18228358 0.14 ENSDART00000167937
prolyl 4-hydroxylase, beta polypeptide
chr12_-_14143344 0.14 ENSDART00000152742
bucky ball 2-like
chr3_-_13921173 0.14 ENSDART00000159177
ENSDART00000165174
si:dkey-61n16.5
chr9_+_50001746 0.14 ENSDART00000058892
solute carrier family 38, member 11
chr1_+_52392511 0.13 ENSDART00000144025
si:ch211-217k17.8
chr15_+_34988148 0.13 ENSDART00000076269
coiled-coil domain containing 105
chr8_+_16758304 0.13 ENSDART00000133514
ELOVL fatty acid elongase 7a
chr18_+_2228737 0.13 ENSDART00000165301
RAB27A, member RAS oncogene family
chr24_+_16985181 0.13 ENSDART00000135580
eukaryotic translation initiation factor 2, subunit 3 gamma
chr23_-_32162810 0.13 ENSDART00000155905
nuclear receptor subfamily 4, group A, member 1
chr6_+_14301214 0.13 ENSDART00000129491
transmembrane protein 182b
chr10_+_16584382 0.13 ENSDART00000112039

chr8_-_12867128 0.13 ENSDART00000142201
solute carrier family 2 (facilitated glucose transporter), member 6
chr11_+_3254524 0.13 ENSDART00000159459
premelanosome protein a
chr14_+_40874608 0.13 ENSDART00000168448
si:ch211-106m9.1
chr12_+_16168342 0.13 ENSDART00000079326
ENSDART00000170024
low density lipoprotein receptor-related protein 2b
chr20_-_48485354 0.13 ENSDART00000124040
ENSDART00000148437
insulinoma-associated 1a
chr17_-_21884323 0.12 ENSDART00000155574
CUB and zona pellucida-like domains 1, tandem duplicate 1
chr13_-_25720876 0.12 ENSDART00000142404
ENSDART00000146487
si:dkey-192p21.6
chr19_-_10330778 0.12 ENSDART00000081465
ENSDART00000136653
ENSDART00000171232
coiled-coil domain containing 106b
chr23_+_31912882 0.12 ENSDART00000140505
armadillo repeat containing 1, like
chr2_+_29842878 0.12 ENSDART00000131376
si:ch211-207d6.2
chr16_+_23303859 0.12 ENSDART00000006093
solute carrier family 50 (sugar efflux transporter), member 1
chr13_+_25720969 0.12 ENSDART00000046050
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr3_+_17933132 0.12 ENSDART00000104299
ENSDART00000162144
ENSDART00000162242
ENSDART00000166289
ENSDART00000171101
ENSDART00000164853
2',3'-cyclic nucleotide 3' phosphodiesterase
chr19_+_30884960 0.12 ENSDART00000140603
ENSDART00000183224
ENSDART00000135484
ENSDART00000139599
tyrosyl-tRNA synthetase
chr11_-_38533505 0.12 ENSDART00000113894
solute carrier family 45, member 3
chr4_+_76637548 0.12 ENSDART00000133799
membrane-spanning 4-domains, subfamily A, member 17A.9
chr3_-_34072446 0.12 ENSDART00000151528
immunoglobulin heavy variable 8-2
chr11_-_35171162 0.12 ENSDART00000017393
TRAF-interacting protein
chr25_+_3549584 0.12 ENSDART00000165913
coiled-coil domain containing 77
chr3_+_23092762 0.12 ENSDART00000142884
ENSDART00000024136
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr23_-_33709964 0.12 ENSDART00000143333
ENSDART00000130338
POU class 6 homeobox 1
chr7_-_6445129 0.11 ENSDART00000172825
Histone H3.2
chr19_+_30884706 0.11 ENSDART00000052126
tyrosyl-tRNA synthetase
chr1_-_55248496 0.11 ENSDART00000098615
nanos homolog 3

Network of associatons between targets according to the STRING database.

First level regulatory network of lmx1ba+lmx1bb_lmx1al

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0060631 regulation of meiosis I(GO:0060631)
0.2 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.3 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.1 0.8 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 0.3 GO:0048785 hatching gland development(GO:0048785)
0.1 0.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.3 GO:0010873 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873) high-density lipoprotein particle assembly(GO:0034380)
0.1 0.2 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.3 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.2 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.4 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.0 0.1 GO:0097435 fibril organization(GO:0097435)
0.0 0.6 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.2 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.1 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.3 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.2 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.4 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.2 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.2 GO:0040038 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.8 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.2 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0070265 necrotic cell death(GO:0070265) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.3 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.2 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.3 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.4 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.2 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:0061549 sympathetic ganglion development(GO:0061549)
0.0 0.0 GO:0031646 positive regulation of neurological system process(GO:0031646)
0.0 0.2 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.0 GO:0006522 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.0 0.2 GO:2000344 binding of sperm to zona pellucida(GO:0007339) cell-cell recognition(GO:0009988) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.6 GO:0007602 phototransduction(GO:0007602)
0.0 0.0 GO:0034969 histone arginine methylation(GO:0034969)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 0.4 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 0.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.2 GO:0043220 compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220)
0.1 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.0 0.1 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0071914 prominosome(GO:0071914)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.4 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0009374 biotin binding(GO:0009374)
0.2 0.6 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.4 GO:0032052 bile acid binding(GO:0032052)
0.1 0.3 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 1.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity(GO:0047173)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.4 GO:0016229 steroid dehydrogenase activity(GO:0016229)
0.0 0.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.2 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.0 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.0 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 0.6 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0051119 sugar transmembrane transporter activity(GO:0051119)
0.0 0.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates