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PRJNA207719: Tissue specific transcriptome profiling

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Results for lhx5

Z-value: 1.38

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Transcription factors associated with lhx5

Gene Symbol Gene ID Gene Info
ENSDARG00000057936 LIM homeobox 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
lhx5dr11_v1_chr21_-_15929041_159290410.856.7e-02Click!

Activity profile of lhx5 motif

Sorted Z-values of lhx5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_9669717 2.17 ENSDART00000004604
si:dkey-153k10.9
chr15_-_44601331 1.91 ENSDART00000161514
zgc:165508
chr9_+_7998794 1.44 ENSDART00000138167
myosin XVI
chr4_-_5019113 1.44 ENSDART00000189321
ENSDART00000081990
striatin interacting protein 2
chr11_-_1509773 1.44 ENSDART00000050762
phosphatase and actin regulator 3b
chr3_-_49566364 1.43 ENSDART00000161507
zgc:153426
chr21_-_20939488 1.43 ENSDART00000039043
regulator of G protein signaling 7 binding protein b
chr6_-_11768198 1.43 ENSDART00000183463
membrane-associated ring finger (C3HC4) 7
chr6_+_7444899 1.36 ENSDART00000053775
ADP-ribosylation factor 3b
chr16_-_28856112 1.35 ENSDART00000078543
synaptotagmin XIb
chr19_+_31771270 1.32 ENSDART00000147474
stathmin 2b
chr12_+_1139690 1.27 ENSDART00000160442

chr19_-_26869103 1.27 ENSDART00000089699
proline-rich transmembrane protein 1
chr17_+_15433518 1.23 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr10_-_2524917 1.22 ENSDART00000188642

chr17_+_15433671 1.21 ENSDART00000149568
fatty acid binding protein 7, brain, a
chr2_-_9059955 1.17 ENSDART00000022768
adenylate kinase 5
chr24_+_24461341 1.14 ENSDART00000147658
basic helix-loop-helix family, member e22
chr9_+_54039006 1.12 ENSDART00000112441
toll-like receptor 7
chr10_-_2524297 1.11 ENSDART00000192475

chr25_-_19420949 1.03 ENSDART00000181338
microtubule-associated protein 1Ab
chr17_-_16965809 1.03 ENSDART00000153697
neurexin 3a
chr10_+_45089820 1.02 ENSDART00000175481
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2
chr9_+_24159280 0.98 ENSDART00000184624
ENSDART00000178422
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a
chr12_+_7497882 0.91 ENSDART00000134608
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr24_+_24461558 0.90 ENSDART00000182424
basic helix-loop-helix family, member e22
chr20_+_52389858 0.86 ENSDART00000185863
ENSDART00000166651
Rho GTPase activating protein 39
chr5_-_31901468 0.86 ENSDART00000147814
ENSDART00000141446
coronin, actin binding protein, 1Cb
chr25_-_9805269 0.86 ENSDART00000192048
leucine rich repeat containing 4C
chr2_-_30668580 0.86 ENSDART00000087270
catenin (cadherin-associated protein), delta 2b
chr11_+_30057762 0.85 ENSDART00000164139
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr12_-_17712393 0.83 ENSDART00000143534
ENSDART00000010144
parvalbumin 2
chr3_-_48716422 0.83 ENSDART00000164979
si:ch211-114m9.1
chr16_-_41004731 0.82 ENSDART00000102591
si:dkey-201i6.2
chr21_+_30502002 0.81 ENSDART00000043727
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3a
chr13_-_29421331 0.79 ENSDART00000150228
choline O-acetyltransferase a
chr20_+_32552912 0.78 ENSDART00000009691
Scm polycomb group protein like 4
chr21_-_17482465 0.77 ENSDART00000004548
BarH-like homeobox 1b
chr24_-_7697274 0.77 ENSDART00000186077
synaptotagmin Vb
chr2_+_20430366 0.77 ENSDART00000155108
si:ch211-153l6.6
chr23_+_16638639 0.74 ENSDART00000143545
syntaphilin b
chr12_+_45200744 0.73 ENSDART00000098932
WW domain binding protein 2
chr19_+_5480327 0.72 ENSDART00000148794
junction plakoglobin b
chr5_-_67911111 0.72 ENSDART00000051833
GS homeobox 1
chr16_+_2820340 0.72 ENSDART00000092299
ENSDART00000192931
ENSDART00000148512
si:dkey-288i20.2
chr17_-_200316 0.72 ENSDART00000190561

chr9_+_24159725 0.68 ENSDART00000137756
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a
chr9_+_34641237 0.68 ENSDART00000133996
short stature homeobox
chr2_+_2223837 0.68 ENSDART00000101038
ENSDART00000129354
transmembrane inner ear
chr24_-_35767501 0.65 ENSDART00000105680
ENSDART00000042290
ENSDART00000166264
dystrobrevin, alpha
chr8_+_36500061 0.64 ENSDART00000185840
solute carrier family 7, member 4
chr5_-_38094130 0.64 ENSDART00000131831
si:ch211-284e13.4
chr6_-_40029423 0.63 ENSDART00000103230
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b
chr5_-_21422390 0.63 ENSDART00000144198
teneurin transmembrane protein 1
chr16_-_28658341 0.62 ENSDART00000148456
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr12_+_25600685 0.61 ENSDART00000077157
SIX homeobox 3b
chr6_-_1865323 0.60 ENSDART00000155775
discs, large (Drosophila) homolog-associated protein 4b
chr10_-_43404027 0.59 ENSDART00000086227
EGF-like repeats and discoidin I-like domains 3b
chr9_-_37749973 0.59 ENSDART00000087663
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba
chr8_-_30979494 0.56 ENSDART00000138959
si:ch211-251j10.3
chr15_-_18162647 0.56 ENSDART00000012064
PIH1 domain containing 2
chr10_+_16225117 0.54 ENSDART00000169885
solute carrier family 12 (sodium/potassium/chloride transporter), member 2
chr1_+_6862917 0.53 ENSDART00000182953
erb-b2 receptor tyrosine kinase 4a
chr16_+_28932038 0.53 ENSDART00000149480
natriuretic peptide receptor 1b
chr1_+_29858032 0.53 ENSDART00000054066
zic family member 2 (odd-paired homolog, Drosophila) b
chr4_-_75158035 0.52 ENSDART00000174353

chr24_+_20969358 0.52 ENSDART00000129675
dopamine receptor D3
chr4_-_1801519 0.51 ENSDART00000188604
ENSDART00000135749
nudix (nucleoside diphosphate linked moiety X)-type motif 4b
chr8_+_36500308 0.50 ENSDART00000098701
solute carrier family 7, member 4
chr5_-_6377865 0.50 ENSDART00000031775
zgc:73226
chr22_-_13466246 0.50 ENSDART00000134035
contactin associated protein-like 5b
chr13_+_11440389 0.50 ENSDART00000186463
zinc finger and BTB domain containing 18
chr12_+_18681477 0.50 ENSDART00000127981
ENSDART00000143979
regulator of G protein signaling 9b
chr2_-_17393216 0.50 ENSDART00000123137
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr9_-_42418470 0.50 ENSDART00000144353
calcitonin receptor-like a
chr3_+_39853788 0.48 ENSDART00000154869
calcium channel, voltage-dependent, T type, alpha 1H subunit a
chr4_-_2219705 0.47 ENSDART00000131046
si:ch73-278m9.1
chr4_-_5018705 0.47 ENSDART00000154025
striatin interacting protein 2
chr23_+_26946429 0.46 ENSDART00000185564
calcium channel, voltage-dependent, beta 3b
chr7_-_71829649 0.46 ENSDART00000160449
calcium channel, voltage-dependent, beta 2a
chr7_-_74057288 0.46 ENSDART00000189740

chr3_-_11624694 0.46 ENSDART00000127157
hepatic leukemia factor a
chr17_-_40956035 0.45 ENSDART00000124715
si:dkey-16j16.4
chr24_-_11309477 0.45 ENSDART00000137257
myosin VIIA and Rab interacting protein
chr15_-_20949692 0.43 ENSDART00000185548
tubulin folding cofactor E-like a
chr20_+_19512727 0.42 ENSDART00000063696
all-trans retinoic acid-induced differentiation factor
chr25_-_25058508 0.42 ENSDART00000087570
ENSDART00000178891

chr6_+_35362225 0.41 ENSDART00000133783
ENSDART00000102483
regulator of G protein signaling 4
chr21_+_21195487 0.40 ENSDART00000181746
ENSDART00000184832
RPTOR independent companion of MTOR, complex 2b
chr18_+_8320165 0.39 ENSDART00000092053
choline kinase beta
chr22_-_11614973 0.39 ENSDART00000063135
phosphate cytidylyltransferase 2, ethanolamine
chr17_-_4245902 0.39 ENSDART00000151851
growth differentiation factor 3
chr9_+_38074082 0.37 ENSDART00000017833
calcium channel, voltage-dependent, beta 4a subunit
chr1_+_6172786 0.37 ENSDART00000126468
protein kinase, AMP-activated, gamma 3a non-catalytic subunit
chr23_-_20051369 0.37 ENSDART00000049836
biglycan b
chr1_+_41498188 0.36 ENSDART00000191934
ENSDART00000146310
deltex 4, E3 ubiquitin ligase
chr21_-_22635245 0.36 ENSDART00000115224
ENSDART00000101782
nectin cell adhesion molecule 1a
chr17_+_28533102 0.35 ENSDART00000156218
MAM domain containing glycosylphosphatidylinositol anchor 2a
chr15_-_46718759 0.35 ENSDART00000085926
ENSDART00000154577
zgc:162872
chr6_-_57539141 0.34 ENSDART00000156967
itchy E3 ubiquitin protein ligase a
chr2_-_17392799 0.34 ENSDART00000136470
ENSDART00000141188
ST3 beta-galactoside alpha-2,3-sialyltransferase 3b
chr15_-_21014270 0.33 ENSDART00000154019
si:ch211-212c13.10
chr1_-_50438247 0.32 ENSDART00000114098
dickkopf WNT signaling pathway inhibitor 2
chr5_-_48664522 0.32 ENSDART00000083229
metallo-beta-lactamase domain containing 2
chr6_+_49551614 0.32 ENSDART00000022581
RAB22A, member RAS oncogene family
chr1_-_15797663 0.32 ENSDART00000177122
sarcoglycan zeta
chr24_-_33873451 0.32 ENSDART00000159840
acid-sensing (proton-gated) ion channel 1c
chr4_+_2482046 0.31 ENSDART00000103371
zinc finger, DHHC-type containing 17
chr5_-_66397688 0.31 ENSDART00000161483
huntingtin interacting protein 1 related b
chr17_-_25831569 0.31 ENSDART00000148743
hedgehog acyltransferase
chr11_-_22371105 0.31 ENSDART00000146873
transmembrane protein 183A
chr22_-_28226948 0.31 ENSDART00000147686
si:dkey-222p3.1
chr2_+_11923615 0.31 ENSDART00000126118
TROVE domain family, member 2
chr5_+_21144269 0.30 ENSDART00000028087
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr15_-_14552101 0.30 ENSDART00000171169
numb homolog (Drosophila)-like
chr16_-_27677930 0.29 ENSDART00000145991
transforming growth factor beta regulator 4
chr23_+_41800052 0.29 ENSDART00000141484
prodynorphin
chr11_+_40812590 0.28 ENSDART00000186690
ERBB receptor feedback inhibitor 1a
chr23_-_17509656 0.28 ENSDART00000148423
DnaJ (Hsp40) homolog, subfamily C, member 5ab
chr18_+_46382484 0.27 ENSDART00000024202
ENSDART00000142790
dynein assembly factor with WDR repeat domains 1
chr12_-_48006835 0.27 ENSDART00000108989
ADAM metallopeptidase with thrombospondin type 1 motif, 14
chr21_+_34976600 0.26 ENSDART00000191672
ENSDART00000139635
RNA binding motif protein 11
chr9_+_2574122 0.26 ENSDART00000166326
ENSDART00000191822
si:ch73-167c12.2
chr2_-_16216568 0.26 ENSDART00000173758
Rho guanine nucleotide exchange factor (GEF) 4
chr21_+_25802190 0.25 ENSDART00000128987
neurofibromin 2b (merlin)
chr9_+_55154414 0.25 ENSDART00000182924
anosmin 1
chr11_-_26832685 0.25 ENSDART00000153519
IQ motif and Sec7 domain 1b
chr15_-_22074315 0.25 ENSDART00000149830
dopamine receptor D2a
chr3_-_39180048 0.24 ENSDART00000049720
cyclin-dependent kinase 21
chr1_+_54124209 0.24 ENSDART00000187730

chr7_+_24023653 0.24 ENSDART00000141165
TERF1 (TRF1)-interacting nuclear factor 2
chr9_-_38398789 0.23 ENSDART00000188384
zinc finger protein 142
chr22_-_20812822 0.23 ENSDART00000193778
DOT1-like histone H3K79 methyltransferase
chr15_+_9327252 0.23 ENSDART00000144381
sarcoglycan, gamma
chr5_+_13427826 0.22 ENSDART00000083359
SEC14-like lipid binding 8
chr17_+_16564921 0.22 ENSDART00000151904
forkhead box N3
chr24_+_21540842 0.22 ENSDART00000091529
WAS protein family, member 3b
chr23_-_18707418 0.22 ENSDART00000144668
ENSDART00000141205
ENSDART00000016765
zgc:103759
chr6_-_12912606 0.21 ENSDART00000164640
islet cell autoantigen 1-like
chr6_-_58764672 0.21 ENSDART00000154322
sterol O-acyltransferase 2
chr25_+_3994823 0.21 ENSDART00000154020
EPS8 like 2
chr25_-_13490744 0.21 ENSDART00000056721
lactate dehydrogenase D
chr11_-_34478225 0.21 ENSDART00000189604
xyloside xylosyltransferase 1
chr5_-_13251907 0.21 ENSDART00000176774
ENSDART00000030553
DNA topoisomerase III beta
chr14_+_36521005 0.20 ENSDART00000192286
si:dkey-237h12.3
chr7_+_66884291 0.20 ENSDART00000187499
SET binding factor 2
chr12_+_36416173 0.20 ENSDART00000190278
unkempt family zinc finger
chr7_-_57509447 0.20 ENSDART00000051973
ENSDART00000147036
sirtuin 3
chr22_-_23545828 0.19 ENSDART00000161253
crumbs family member 1, photoreceptor morphogenesis associated
chr3_-_26787430 0.19 ENSDART00000087047
RAB40c, member RAS oncogene family
chr17_+_38476300 0.19 ENSDART00000123298
StAR-related lipid transfer (START) domain containing 9
chr24_+_12989727 0.19 ENSDART00000126842
ENSDART00000129309
hypothetical protein FLJ11011-like (H. sapiens)
chr6_+_25257728 0.19 ENSDART00000162581
kynurenine aminotransferase 3
chr22_-_14739491 0.19 ENSDART00000133385
low density lipoprotein receptor-related protein 1Ba
chr18_-_17485419 0.19 ENSDART00000018764
forkhead box L1
chr23_+_27051919 0.18 ENSDART00000054237
prostaglandin E synthase 3a (cytosolic)
chr14_-_42231293 0.18 ENSDART00000185486

chr20_-_53981626 0.17 ENSDART00000023550
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2
chr17_+_22577472 0.16 ENSDART00000045099
Yip1 domain family, member 4
chr4_-_73447058 0.16 ENSDART00000172042
si:ch73-120g24.4
chr24_+_28953089 0.16 ENSDART00000153761
RNA-binding region (RNP1, RRM) containing 3
chr12_-_3773869 0.16 ENSDART00000092983
si:ch211-166g5.4
chr11_-_6068375 0.16 ENSDART00000167672
ENSDART00000122262
BRISC and BRCA1 A complex member 1
chr22_-_23545307 0.16 ENSDART00000166915
crumbs family member 1, photoreceptor morphogenesis associated
chr8_+_36560019 0.15 ENSDART00000136418
ENSDART00000061378
ENSDART00000185237
splicing factor 3a, subunit 1
chr19_+_40069524 0.15 ENSDART00000151365
ENSDART00000140926
zinc finger, MYM-type 4
chr3_+_7808459 0.15 ENSDART00000162374
hook microtubule-tethering protein 2
chr9_+_28598577 0.15 ENSDART00000142623
ENSDART00000135947
si:ch73-7i4.1
chr23_+_31405497 0.14 ENSDART00000053546
SH3 domain binding glutamate-rich protein like 2
chr20_+_22799641 0.14 ENSDART00000131132
sec1 family domain containing 2
chr11_-_45141309 0.14 ENSDART00000181736
calcium activated nucleotidase 1b
chr8_+_50953776 0.14 ENSDART00000013870
zgc:56596
chr21_+_27278120 0.13 ENSDART00000193882
si:dkey-175m17.7
chr5_-_41494831 0.13 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr15_-_20939579 0.13 ENSDART00000152371
ubiquitin specific peptidase 2a
chr10_-_43568239 0.13 ENSDART00000131731
ENSDART00000097433
ENSDART00000131309
myocyte enhancer factor 2ca
chr13_-_38730267 0.13 ENSDART00000157524
LMBR1 domain containing 1
chr17_+_43595692 0.13 ENSDART00000156271
cilia and flagella associated protein 99
chr22_-_5252005 0.12 ENSDART00000132942
ENSDART00000081801
nicalin
chr4_+_57881965 0.12 ENSDART00000162234
si:dkeyp-44b5.4
chr24_+_17260001 0.12 ENSDART00000066765
bmi1 polycomb ring finger oncogene 1a
chr3_-_26806032 0.12 ENSDART00000143710
phosphatidylinositol glycan anchor biosynthesis, class Q
chr20_-_13774826 0.12 ENSDART00000063831
opsin 8, group member c
chr8_+_7801060 0.12 ENSDART00000161618
transcription factor binding to IGHM enhancer 3a
chr6_-_21582444 0.11 ENSDART00000151339
si:dkey-43k4.3
chr7_-_7692992 0.11 ENSDART00000192619
aminoadipate aminotransferase
chr3_+_40164129 0.11 ENSDART00000102526
growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
chr16_-_41515662 0.11 ENSDART00000166201
ENSDART00000127243
sialic acid binding Ig-like lectin 15, like
chr4_+_72723304 0.10 ENSDART00000186791
ENSDART00000158902
ENSDART00000191925
RAB3A interacting protein (rabin3)
chr7_-_7692723 0.10 ENSDART00000183352
aminoadipate aminotransferase
chr1_-_669717 0.10 ENSDART00000160564
cysteine/tyrosine-rich 1
chr6_-_50730749 0.10 ENSDART00000157153
ENSDART00000110441
phosphatidylinositol glycan anchor biosynthesis, class U
chr9_-_12811936 0.10 ENSDART00000188490
myosin X-like 3
chr5_-_32396929 0.09 ENSDART00000023977
F-box and WD repeat domain containing 2
chr24_-_31425799 0.09 ENSDART00000157998
cyclic nucleotide gated channel beta 3, tandem duplicate 1
chr21_-_35534401 0.09 ENSDART00000112308
si:dkeyp-23e4.3
chr7_+_59020972 0.09 ENSDART00000157873
3-hydroxyacyl-CoA dehydratase 1
chr7_-_66868543 0.09 ENSDART00000149680
adenosine monophosphate deaminase 3a
chr11_+_11974708 0.09 ENSDART00000125060
zgc:64002
chr11_-_2838699 0.09 ENSDART00000066189
LHFPL tetraspan subfamily member 5a

Network of associatons between targets according to the STRING database.

First level regulatory network of lhx5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.3 0.8 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.2 1.7 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.2 0.8 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.7 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 0.7 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.8 GO:0090467 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.1 1.9 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.1 0.4 GO:0019062 virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)
0.1 0.4 GO:0021611 facial nerve formation(GO:0021611)
0.1 0.4 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 0.5 GO:0071543 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 0.6 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.5 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.2 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.7 GO:0050975 sensory perception of touch(GO:0050975)
0.1 2.9 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.2 GO:0034729 histone H3-K79 methylation(GO:0034729) regulation of transcription regulatory region DNA binding(GO:2000677)
0.1 0.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.1 0.3 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 0.5 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 2.4 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.5 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.0 0.3 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:0036076 ligamentous ossification(GO:0036076)
0.0 0.5 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 0.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 0.7 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.6 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.3 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.8 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.9 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.2 GO:0035138 pectoral fin morphogenesis(GO:0035138)
0.0 0.5 GO:0070654 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.0 1.4 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.5 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0072401 signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in G2 DNA damage checkpoint(GO:0072425)
0.0 0.2 GO:0034435 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 0.5 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.7 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.0 0.1 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 0.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.2 GO:0016074 snoRNA metabolic process(GO:0016074)
0.0 0.2 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.6 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.7 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.3 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.2 GO:0007004 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.1 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 1.0 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.0 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.0 0.3 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.8 GO:0060216 definitive hemopoiesis(GO:0060216)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0097255 R2TP complex(GO:0097255)
0.1 0.8 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.3 GO:0030426 growth cone(GO:0030426)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.0 1.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.8 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 2.0 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 1.4 GO:0098858 actin-based cell projection(GO:0098858)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 1.6 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.0 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.2 0.5 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.2 2.4 GO:0005504 fatty acid binding(GO:0005504)
0.2 0.5 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.8 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.1 0.8 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.5 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.2 GO:1990174 m7G(5')pppN diphosphatase activity(GO:0050072) phosphodiesterase decapping endonuclease activity(GO:1990174)
0.1 0.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.2 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.8 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.5 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.2 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.1 0.8 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.2 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 2.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 1.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 1.0 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0031628 opioid receptor binding(GO:0031628)
0.0 1.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.4 GO:0016208 AMP binding(GO:0016208)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation