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PRJNA207719: Tissue specific transcriptome profiling

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Results for klf12b

Z-value: 2.97

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Transcription factors associated with klf12b

Gene Symbol Gene ID Gene Info
ENSDARG00000032197 Kruppel-like factor 12b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
klf12bdr11_v1_chr9_+_30720048_307200480.701.9e-01Click!

Activity profile of klf12b motif

Sorted Z-values of klf12b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_13742899 6.50 ENSDART00000104722
cyclin-dependent kinase 5, regulatory subunit 2a (p39)
chr19_-_26863626 3.62 ENSDART00000145568
proline-rich transmembrane protein 1
chr21_-_43949208 2.69 ENSDART00000150983
calcium/calmodulin-dependent protein kinase II alpha
chr2_+_47582681 2.45 ENSDART00000187579
secretogranin II (chromogranin C), b
chr11_-_37509001 2.36 ENSDART00000109753
bassoon (presynaptic cytomatrix protein) b
chr9_-_35155089 2.33 ENSDART00000077901
amyloid beta (A4) precursor protein b
chr5_-_25174420 2.30 ENSDART00000141554
ATP-binding cassette, sub-family A (ABC1), member 2
chr9_-_31278048 2.20 ENSDART00000022204
zic family member 5 (odd-paired homolog, Drosophila)
chr7_-_18601206 2.18 ENSDART00000111636
si:ch211-119e14.2
chr5_-_22501663 2.05 ENSDART00000133174
si:dkey-27p18.5
chr10_+_25222367 1.99 ENSDART00000042767
glutamate receptor, metabotropic 5a
chr23_+_16633951 1.95 ENSDART00000109537
ENSDART00000193323
syntaphilin b
chr18_+_18104235 1.90 ENSDART00000145342
cerebellin 1 precursor
chr2_-_21082695 1.88 ENSDART00000032502
nebulette
chr10_+_22381802 1.85 ENSDART00000112484
neuroligin 2b
chr22_+_696931 1.85 ENSDART00000149712
ENSDART00000009756
G protein-coupled receptor 37 like 1a
chr10_-_20637098 1.82 ENSDART00000080391
shadow of prion protein 2
chr6_+_40591149 1.82 ENSDART00000189060
ENSDART00000188298
fibroblast growth factor receptor substrate 3
chr5_-_23317477 1.81 ENSDART00000090171
neuroligin 3b
chr17_-_52643970 1.79 ENSDART00000190594
sprouty-related, EVH1 domain containing 1
chr12_+_24344963 1.79 ENSDART00000191648
ENSDART00000183180
ENSDART00000088178
ENSDART00000189696
neurexin 1a
chr8_+_31248917 1.76 ENSDART00000112170
un-named hu7912
chr11_+_23957440 1.74 ENSDART00000190721
contactin 2
chr25_+_12640211 1.73 ENSDART00000165108
junctophilin 3
chr1_+_20084389 1.69 ENSDART00000140263
protease, serine, 12 (neurotrypsin, motopsin)
chr6_+_24817852 1.68 ENSDART00000165609
BarH-like homeobox 2
chr8_+_28900689 1.67 ENSDART00000141634
glutamate receptor, ionotropic, delta 2
chr8_+_31119548 1.67 ENSDART00000136578
synapsin I
chr1_-_21483832 1.65 ENSDART00000102790
glycine receptor, beta a
chr12_+_16233077 1.65 ENSDART00000152409
membrane protein, palmitoylated 3b (MAGUK p55 subfamily member 3)
chr19_-_13733870 1.64 ENSDART00000177773
erythrocyte membrane protein band 4.1a
chr9_-_27442339 1.64 ENSDART00000138602
syntaxin binding protein 5-like
chr2_+_22694382 1.61 ENSDART00000139196
kinesin family member 1Ab
chr2_+_24203229 1.56 ENSDART00000138088
microtubule associated protein 4 like
chr21_-_28235361 1.56 ENSDART00000164458
neurexin 2a
chr4_+_19535946 1.56 ENSDART00000192342
ENSDART00000183740
ENSDART00000180812
ENSDART00000180017
leucine rich repeat containing 4.1
chr2_+_27010439 1.55 ENSDART00000030547
cadherin 7a
chr3_-_18710009 1.54 ENSDART00000142478
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein, a
chr8_-_14050758 1.53 ENSDART00000133922
ATPase plasma membrane Ca2+ transporting 3a
chr3_-_19091024 1.52 ENSDART00000188485
ENSDART00000110554
glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca
chr1_+_14283692 1.51 ENSDART00000017679
protein phosphatase 2, regulatory subunit B, gamma a
chr7_-_43840680 1.51 ENSDART00000002279
cadherin 11, type 2, OB-cadherin (osteoblast)
chr5_+_20148671 1.47 ENSDART00000143205
SV2 related protein a
chr4_+_6643421 1.46 ENSDART00000099462
G protein-coupled receptor 85
chr18_+_18612388 1.46 ENSDART00000186455
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr20_+_5564042 1.46 ENSDART00000090934
ENSDART00000127050
neurexin 3b
chr12_+_9817440 1.46 ENSDART00000137081
ENSDART00000123712
RUN domain containing 3Ab
chr11_-_42554290 1.46 ENSDART00000130573
ATPase H+ transporting accessory protein 1 like a
chr8_+_36803415 1.44 ENSDART00000111680
IQ motif and Sec7 domain 2b
chr4_-_23643272 1.44 ENSDART00000112301
ENSDART00000133184
thyrotropin releasing hormone degrading enzyme, tandem duplicate 2
chr15_+_37197494 1.43 ENSDART00000166203
amyloid beta (A4) precursor-like protein 1
chr2_-_14390627 1.43 ENSDART00000172367
SH3-domain GRB2-like (endophilin) interacting protein 1b
chr16_-_29458806 1.42 ENSDART00000047931
leucine rich repeat and Ig domain containing 4b
chr12_+_42574148 1.42 ENSDART00000157855
early B cell factor 3a
chr23_+_35714574 1.42 ENSDART00000164616
tubulin, alpha 1c
chr16_-_44512882 1.41 ENSDART00000191241

chr4_-_1324141 1.41 ENSDART00000180720
pleiotrophin
chr25_-_13842618 1.39 ENSDART00000160258
mitogen-activated protein kinase 8 interacting protein 1a
chr6_+_27667359 1.38 ENSDART00000159624
ENSDART00000049177
RAB6B, member RAS oncogene family a
chr5_+_22098591 1.38 ENSDART00000143676
zinc finger CCCH-type containing 12B
chr3_-_32320537 1.38 ENSDART00000113550
ENSDART00000168483
si:dkey-16p21.7
chr6_-_7842078 1.37 ENSDART00000065507
phospholipid phosphatase related 2b
chr10_+_5159475 1.36 ENSDART00000142507
CDC42 small effector 2
chr25_+_19955598 1.36 ENSDART00000091547
potassium voltage-gated channel, shaker-related subfamily, member 1a
chr7_-_19940473 1.34 ENSDART00000127669
prospero homeobox 1b
chr16_-_12173554 1.33 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr11_+_23933016 1.32 ENSDART00000000486
contactin 2
chr14_+_28281744 1.31 ENSDART00000173292
midline 2
chr19_-_44089509 1.28 ENSDART00000189136
RAD21 cohesin complex component b
chr18_-_16179129 1.28 ENSDART00000125353
solute carrier family 6 (neutral amino acid transporter), member 15
chr19_+_37458610 1.28 ENSDART00000103151
discs, large (Drosophila) homolog-associated protein 3
chr17_+_15433518 1.28 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr17_-_3303805 1.27 ENSDART00000169136

chr21_-_12272543 1.27 ENSDART00000081510
ENSDART00000151297
CUGBP, Elav-like family member 4
chr5_-_31897139 1.26 ENSDART00000191957
coronin, actin binding protein, 1Cb
chr20_-_19422496 1.26 ENSDART00000143658
si:ch211-278j3.3
chr6_-_30210378 1.25 ENSDART00000157359
ENSDART00000113924
leucine rich repeat containing 7
chr20_-_31781941 1.24 ENSDART00000139417
syntaxin binding protein 5a (tomosyn)
chr1_+_38776294 1.24 ENSDART00000170546
WD repeat domain 17
chr17_+_18117358 1.22 ENSDART00000144894
B cell CLL/lymphoma 11Ba
chr24_-_10919588 1.22 ENSDART00000131204
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b
chr14_+_8328645 1.22 ENSDART00000127494
neuregulin 2b
chr16_+_37470717 1.21 ENSDART00000112003
ENSDART00000188431
ENSDART00000192837
adhesion G protein-coupled receptor B1a
chr22_-_22130623 1.19 ENSDART00000113168

chr7_-_30082931 1.19 ENSDART00000075600
tetraspanin 3b
chr21_-_24632778 1.19 ENSDART00000132533
ENSDART00000058370
Rho GTPase activating protein 32b
chr4_+_23223881 1.19 ENSDART00000133056
ENSDART00000089126
thyrotropin releasing hormone degrading enzyme, tandem duplicate 1
chr23_-_12345764 1.19 ENSDART00000133956
phosphatase and actin regulator 3a
chr13_-_31470439 1.18 ENSDART00000076574
reticulon 1a
chr3_-_19133003 1.18 ENSDART00000145215
glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca
chr2_+_55916911 1.18 ENSDART00000189483
ENSDART00000183647
ENSDART00000083470
ataxia, cerebellar, Cayman type b
chr17_-_36896560 1.18 ENSDART00000045287
microtubule-associated protein, RP/EB family, member 3a
chr12_+_2381213 1.17 ENSDART00000188007

chr5_-_55395964 1.16 ENSDART00000145791
prune homolog 2 (Drosophila)
chr3_+_32391540 1.14 ENSDART00000156608
adaptor-related protein complex 2, alpha 1 subunit
chr9_+_40939336 1.13 ENSDART00000100386
myostatin b
chr18_-_14937211 1.13 ENSDART00000141893
megalencephalic leukoencephalopathy with subcortical cysts 1
chr5_-_21970881 1.13 ENSDART00000182907
Cdc42 guanine nucleotide exchange factor (GEF) 9a
chr15_-_26686908 1.12 ENSDART00000185254
PITPNM family member 3
chr22_-_26323893 1.10 ENSDART00000105099
calpain 1, (mu/I) large subunit b
chr24_+_29382109 1.09 ENSDART00000184620
ENSDART00000188414
ENSDART00000186132
ENSDART00000191489
netrin g1a
chr23_-_8373676 1.09 ENSDART00000105135
ENSDART00000158531
opiate receptor-like 1
chr15_+_40188076 1.08 ENSDART00000063779
EF-hand domain family, member D1
chr16_-_44649053 1.08 ENSDART00000184807

chr13_-_5937034 1.07 ENSDART00000045292
sprouty-related, EVH1 domain containing 2b
chr20_-_39219537 1.06 ENSDART00000005764
cytochrome P450, family 39, subfamily A, polypeptide 1
chr3_-_2593859 1.06 ENSDART00000143826
si:dkey-217f16.5
chr15_-_12319065 1.06 ENSDART00000162973
ENSDART00000170543
FXYD domain containing ion transport regulator 6
chr20_+_18580176 1.05 ENSDART00000185310
si:dkeyp-72h1.1
chr7_-_34413392 1.04 ENSDART00000173673
ENSDART00000047208
ENSDART00000174546
MAP-kinase activating death domain
chr10_+_35953068 1.04 ENSDART00000015279
reticulon 4 receptor-like 1a
chr9_-_32753535 1.04 ENSDART00000060006
oligodendrocyte lineage transcription factor 2
chr4_+_8168514 1.04 ENSDART00000150830
ninjurin 2
chr22_+_12431608 1.03 ENSDART00000108609
Rho family GTPase 3a
chr8_-_12468744 1.03 ENSDART00000135019
si:dkeyp-51b7.3
chr8_-_7232413 1.02 ENSDART00000092426
glutamate receptor interacting protein 2a
chr14_+_24845941 1.02 ENSDART00000187513
Rho guanine nucleotide exchange factor (GEF) 37
chr20_+_38201644 0.99 ENSDART00000022694
EH-domain containing 3
chr7_+_26224211 0.99 ENSDART00000173999
VGF nerve growth factor inducible
chr18_-_26675699 0.99 ENSDART00000113280
si:ch211-69m14.1
chr22_+_5103349 0.99 ENSDART00000083474
ataxia, cerebellar, Cayman type a
chr4_+_20263097 0.99 ENSDART00000138820
leucine-rich repeats and transmembrane domains 2a
chr24_+_39137001 0.98 ENSDART00000181086
ENSDART00000183724
ENSDART00000193466
TBC1 domain family, member 24
chr15_+_32821392 0.98 ENSDART00000158272
doublecortin-like kinase 1b
chr14_-_27121854 0.98 ENSDART00000173119
protocadherin 11
chr7_-_46781614 0.97 ENSDART00000173891
teashirt zinc finger homeobox 3b
chr9_+_49659114 0.96 ENSDART00000189643
cysteine and serine rich nuclear protein 3
chr2_+_50094873 0.96 ENSDART00000132307
zinc finger, CCHC domain containing 2
chr16_+_20161805 0.95 ENSDART00000192146
chromosome 16 C2orf66 homolog
chr24_-_21989406 0.94 ENSDART00000032963
apolipoprotein O, b
chr19_-_4010263 0.94 ENSDART00000159605
ENSDART00000165541
MAP7 domain containing 1b
chr8_+_47342586 0.94 ENSDART00000007624
phospholipase C, eta 2a
chr23_+_16638639 0.94 ENSDART00000143545
syntaphilin b
chr3_-_61334589 0.93 ENSDART00000191560
tectonin beta-propeller repeat containing 1b
chr4_-_9557186 0.93 ENSDART00000150569
SH3 and multiple ankyrin repeat domains 3b
chr16_+_14812585 0.92 ENSDART00000134087
collagen, type XIV, alpha 1a
chr19_-_3488860 0.92 ENSDART00000172520
human immunodeficiency virus type I enhancer binding protein 1
chr22_-_600016 0.92 ENSDART00000086434
transmembrane and coiled-coil domain family 2
chr14_+_32022272 0.92 ENSDART00000105760
zic family member 6
chr4_-_18201622 0.91 ENSDART00000133509
ankyrin repeat and sterile alpha motif domain containing 1B
chr20_-_47704973 0.91 ENSDART00000174808
transcription factor AP-2 beta
chr5_-_28679135 0.91 ENSDART00000193585
tenascin C
chr3_+_54047342 0.89 ENSDART00000178486
olfactomedin 2a
chr10_-_34870667 0.88 ENSDART00000161272
doublecortin-like kinase 1a
chr24_+_29381946 0.88 ENSDART00000189551
netrin g1a
chr8_+_25247245 0.88 ENSDART00000045798
adenosine monophosphate deaminase 2b
chr20_+_26349002 0.87 ENSDART00000152842
spectrin repeat containing, nuclear envelope 1a
chr24_-_10828560 0.87 ENSDART00000132282
family with sequence similarity 49, member Bb
chr3_-_22829710 0.87 ENSDART00000055659
cytochrome b561
chr3_-_37476278 0.86 ENSDART00000083442
si:ch211-278a6.1
chr7_-_57933736 0.86 ENSDART00000142580
ankyrin 2b, neuronal
chr15_-_11341635 0.86 ENSDART00000055220
RAB30, member RAS oncogene family
chr20_+_18947314 0.85 ENSDART00000183632
myotubularin related protein 9
chr24_-_31123365 0.85 ENSDART00000182947
transmembrane protein 56a
chr13_+_4505232 0.84 ENSDART00000007500
ENSDART00000161684
phosphodiesterase 10A
chr10_+_29698467 0.84 ENSDART00000163402
discs, large homolog 2 (Drosophila)
chr13_+_25505580 0.82 ENSDART00000140634
inositol polyphosphate-5-phosphatase F
chr8_-_9118958 0.82 ENSDART00000037922
solute carrier family 6 (neurotransmitter transporter), member 8
chr7_+_34620418 0.82 ENSDART00000081338
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr24_+_24461558 0.82 ENSDART00000182424
basic helix-loop-helix family, member e22
chr12_+_21299338 0.81 ENSDART00000074540
ENSDART00000133188
carbonic anhydrase Xa
chr2_+_31833997 0.80 ENSDART00000066788
ependymin related 1
chr20_+_17739923 0.80 ENSDART00000024627
cadherin 2, type 1, N-cadherin (neuronal)
chr5_-_38506981 0.79 ENSDART00000097822
ATPase Na+/K+ transporting subunit beta 2b
chr23_+_11669337 0.79 ENSDART00000131355
contactin 3a, tandem duplicate 1
chr3_-_28750495 0.78 ENSDART00000054408
gsg1-like
chr1_-_51465730 0.78 ENSDART00000074284
sprouty-related, EVH1 domain containing 2a
chr23_+_11669109 0.78 ENSDART00000091416
contactin 3a, tandem duplicate 1
chr4_+_5741733 0.77 ENSDART00000110243
POU class 3 homeobox 2a
chr13_-_11536951 0.77 ENSDART00000018155
adenylosuccinate synthase
chr23_-_24450686 0.77 ENSDART00000189161
spen family transcriptional repressor
chr8_+_42998944 0.76 ENSDART00000048819
Ras association (RalGDS/AF-6) domain family member 2a
chr11_+_7432533 0.76 ENSDART00000180977
adhesion G protein-coupled receptor L2a
chr15_-_13254480 0.76 ENSDART00000190499
zgc:172282
chr5_+_33301005 0.76 ENSDART00000006021
ubiquitin specific peptidase 20
chr9_-_18814737 0.75 ENSDART00000131267
TSC22 domain family, member 1
chr1_+_29183962 0.75 ENSDART00000113735
cysteinyl-tRNA synthetase 2, mitochondrial
chr17_+_10242166 0.75 ENSDART00000170420
C-type lectin domain containing 14A
chr10_+_21776911 0.74 ENSDART00000163077
ENSDART00000186093
protocadherin 1 gamma 22
chr18_+_3243292 0.74 ENSDART00000166580
p21 protein (Cdc42/Rac)-activated kinase 1
chr17_-_8692722 0.74 ENSDART00000148931
ENSDART00000192891
C-terminal binding protein 2a
chr10_-_34867401 0.73 ENSDART00000145545
doublecortin-like kinase 1a
chr25_-_19090479 0.73 ENSDART00000027465
ENSDART00000177670
calcium channel, voltage-dependent, alpha 2/delta subunit 4b
chr15_+_24212847 0.73 ENSDART00000155502
seizure related 6 homolog b
chr2_-_48356787 0.73 ENSDART00000098004
period circadian clock 2
chr20_-_23226453 0.73 ENSDART00000142721
DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)
chr3_+_32396741 0.73 ENSDART00000156447
adaptor-related protein complex 2, alpha 1 subunit
chr23_-_24483311 0.72 ENSDART00000185793
ENSDART00000109248
spen family transcriptional repressor
chr15_-_30505607 0.72 ENSDART00000155212
musashi RNA-binding protein 2b
chr4_-_28158335 0.72 ENSDART00000134605
GRAM domain containing 4a
chr9_-_22963897 0.72 ENSDART00000133676
si:dkey-91i10.2
chr7_+_33314925 0.72 ENSDART00000148590
coronin, actin binding protein, 2Ba
chr21_+_22158744 0.72 ENSDART00000101732
calpain 5b
chr9_+_24126223 0.72 ENSDART00000132045
post-GPI attachment to proteins 1
chr8_+_36500308 0.71 ENSDART00000098701
solute carrier family 7, member 4
chr10_-_22828302 0.71 ENSDART00000079459
ENSDART00000100468
period circadian clock 1a
chr8_-_13177536 0.71 ENSDART00000100992
zgc:194990
chr19_+_27479838 0.70 ENSDART00000103922
alpha tubulin acetyltransferase 1
chr14_-_2209742 0.70 ENSDART00000054889
protocadherin 2 alpha b 5
chr14_-_2213660 0.70 ENSDART00000162537
protocadherin 2 alpha b 3

Network of associatons between targets according to the STRING database.

First level regulatory network of klf12b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.7 2.0 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.6 3.6 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.6 2.9 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.3 3.7 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.3 1.3 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.3 2.2 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.3 3.3 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.3 0.9 GO:0014814 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.3 1.4 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.3 1.1 GO:0045843 negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.3 0.8 GO:0035142 hindbrain structural organization(GO:0021577) dorsal fin morphogenesis(GO:0035142) cell motility involved in somitogenic axis elongation(GO:0090247) cell migration involved in somitogenic axis elongation(GO:0090248)
0.3 1.0 GO:0021742 abducens nucleus development(GO:0021742)
0.2 0.7 GO:2000434 regulation of protein neddylation(GO:2000434)
0.2 2.4 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.2 1.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 3.9 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.2 0.8 GO:0021856 pallium development(GO:0021543) cerebral cortex cell migration(GO:0021795) cerebral cortex tangential migration(GO:0021800) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cerebral cortex development(GO:0021987)
0.2 0.7 GO:0003232 bulbus arteriosus development(GO:0003232)
0.2 0.5 GO:1904969 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.2 0.7 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.2 2.6 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.2 0.9 GO:0036371 protein localization to T-tubule(GO:0036371)
0.2 6.5 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.2 1.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 1.3 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.1 0.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 1.3 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 1.8 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 1.2 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 2.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.7 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.4 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 3.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.4 GO:0045730 respiratory burst(GO:0045730)
0.1 0.7 GO:0045475 locomotor rhythm(GO:0045475)
0.1 1.6 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 2.9 GO:0070831 basement membrane assembly(GO:0070831)
0.1 1.1 GO:0034394 protein localization to cell surface(GO:0034394)
0.1 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.5 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 1.3 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.1 1.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 2.0 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.1 0.5 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 0.7 GO:0060118 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.1 1.5 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 1.1 GO:0019233 sensory perception of pain(GO:0019233)
0.1 1.3 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.1 0.8 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 2.9 GO:0050708 regulation of protein secretion(GO:0050708)
0.1 0.8 GO:0001964 startle response(GO:0001964)
0.1 1.2 GO:1903288 positive regulation of sodium ion transport(GO:0010765) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.1 0.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 1.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.6 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 0.9 GO:0042407 cristae formation(GO:0042407)
0.1 0.9 GO:0032264 IMP salvage(GO:0032264)
0.1 0.5 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 0.2 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1 2.5 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.1 1.1 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.4 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.1 0.6 GO:0034605 cellular response to heat(GO:0034605)
0.1 0.2 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.2 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 1.4 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 1.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 1.6 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 0.9 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 0.3 GO:1902765 amino acid import(GO:0043090) L-arginine import(GO:0043091) L-amino acid import(GO:0043092) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.1 1.0 GO:0008354 germ cell migration(GO:0008354)
0.1 2.2 GO:0046328 regulation of JNK cascade(GO:0046328)
0.1 1.5 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0061072 iris morphogenesis(GO:0061072)
0.0 1.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.9 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 2.0 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.7 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.7 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.3 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.3 GO:0061337 cardiac conduction(GO:0061337)
0.0 1.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 1.8 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.6 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 1.0 GO:1902667 regulation of axon guidance(GO:1902667)
0.0 0.5 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.9 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.5 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.3 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0 0.3 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.7 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.3 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 1.9 GO:0003146 heart jogging(GO:0003146)
0.0 0.9 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 4.0 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.3 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.2 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.8 GO:0008593 regulation of Notch signaling pathway(GO:0008593)
0.0 5.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:2000374 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.0 2.7 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 1.7 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.0 0.3 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.0 1.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 1.6 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.2 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 1.3 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.4 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.3 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 0.7 GO:0006505 GPI anchor metabolic process(GO:0006505)
0.0 0.7 GO:0019835 cytolysis(GO:0019835)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.7 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.4 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.3 GO:0007254 JNK cascade(GO:0007254)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 1.5 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.0 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.5 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.1 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.0 0.2 GO:0030816 activation of adenylate cyclase activity(GO:0007190) positive regulation of cAMP metabolic process(GO:0030816) positive regulation of cAMP biosynthetic process(GO:0030819) positive regulation of adenylate cyclase activity(GO:0045762)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370) mRNA methylation(GO:0080009)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.7 GO:0031638 zymogen activation(GO:0031638)
0.0 0.1 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.8 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.2 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.1 GO:0045738 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.0 0.9 GO:0021510 spinal cord development(GO:0021510)
0.0 0.6 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.7 GO:0003401 axis elongation(GO:0003401)
0.0 0.9 GO:0022900 electron transport chain(GO:0022900)
0.0 0.7 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.7 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.2 GO:0043534 blood vessel endothelial cell migration(GO:0043534)
0.0 0.6 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 0.4 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 1.2 GO:0045216 cell-cell junction organization(GO:0045216)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.6 1.9 GO:0060077 inhibitory synapse(GO:0060077)
0.3 1.7 GO:0043083 synaptic cleft(GO:0043083)
0.2 1.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.2 2.9 GO:0044295 axonal growth cone(GO:0044295)
0.2 2.4 GO:0098982 GABA-ergic synapse(GO:0098982)
0.2 1.3 GO:0030892 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.2 2.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 1.9 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 1.2 GO:0001650 fibrillar center(GO:0001650)
0.1 0.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.4 GO:0033270 paranode region of axon(GO:0033270) juxtaparanode region of axon(GO:0044224)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 2.0 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 0.9 GO:0061617 MICOS complex(GO:0061617)
0.1 0.8 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 0.3 GO:0016460 myosin II complex(GO:0016460)
0.1 0.6 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 2.8 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 1.0 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.8 GO:0014704 intercalated disc(GO:0014704)
0.1 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.5 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 1.3 GO:0060170 ciliary membrane(GO:0060170)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.1 0.9 GO:0030315 T-tubule(GO:0030315)
0.1 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 2.6 GO:0016342 catenin complex(GO:0016342)
0.0 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.2 GO:0070724 BMP receptor complex(GO:0070724)
0.0 1.2 GO:0035371 microtubule plus-end(GO:0035371)
0.0 7.1 GO:0099572 postsynaptic specialization(GO:0099572)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 5.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.0 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 2.7 GO:0031201 SNARE complex(GO:0031201)
0.0 0.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.7 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.1 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 3.4 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 0.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0097541 axonemal basal plate(GO:0097541)
0.0 0.7 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 2.5 GO:0030141 secretory granule(GO:0030141)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.6 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.7 GO:0005871 kinesin complex(GO:0005871)
0.0 2.6 GO:0030424 axon(GO:0030424)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 1.0 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 2.3 GO:0035770 ribonucleoprotein granule(GO:0035770)
0.0 0.5 GO:0016605 PML body(GO:0016605)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.4 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.6 GO:0030133 transport vesicle(GO:0030133)
0.0 3.4 GO:0043005 neuron projection(GO:0043005)
0.0 1.3 GO:0005802 trans-Golgi network(GO:0005802)
0.0 3.6 GO:0045202 synapse(GO:0045202)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 3.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.3 0.9 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.3 1.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.3 2.0 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.3 0.8 GO:0052834 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.3 1.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.2 0.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 1.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 2.0 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 0.6 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.2 0.6 GO:0030882 lipid antigen binding(GO:0030882)
0.2 1.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 3.2 GO:0045159 myosin II binding(GO:0045159)
0.2 3.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 3.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.7 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 2.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.1 1.1 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.3 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 3.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.1 0.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.6 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 1.3 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.3 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 0.2 GO:0001607 neuromedin U receptor activity(GO:0001607)
0.1 1.9 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.9 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.8 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 2.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.2 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.0 GO:0048495 Roundabout binding(GO:0048495)
0.1 5.4 GO:0008201 heparin binding(GO:0008201)
0.1 1.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 2.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 1.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 1.7 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.1 2.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.7 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.2 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.3 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.7 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.2 GO:0070883 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.0 0.9 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 3.7 GO:0045296 cadherin binding(GO:0045296)
0.0 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.8 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.1 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.6 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.4 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 2.5 GO:0042626 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.6 GO:0017022 myosin binding(GO:0017022)
0.0 3.9 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.1 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.8 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.6 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 2.0 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.9 PID ARF 3PATHWAY Arf1 pathway
0.1 1.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 0.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 2.3 PID SHP2 PATHWAY SHP2 signaling
0.1 1.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 0.7 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.3 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.3 1.7 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.2 2.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 1.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 1.9 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 1.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.7 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 1.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 0.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 2.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.5 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.0 0.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway