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PRJNA207719: Tissue specific transcriptome profiling

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Results for klf12a

Z-value: 0.98

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Transcription factors associated with klf12a

Gene Symbol Gene ID Gene Info
ENSDARG00000015312 Kruppel-like factor 12a
ENSDARG00000115152 Kruppel-like factor 12a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
klf12adr11_v1_chr1_+_34527213_345272130.069.3e-01Click!

Activity profile of klf12a motif

Sorted Z-values of klf12a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_58221163 2.19 ENSDART00000157939

chr1_+_57371447 1.54 ENSDART00000152229
ENSDART00000181077
si:dkey-27j5.3
chr10_+_1668106 1.38 ENSDART00000142278
small G protein signaling modulator 1b
chr1_-_59176949 1.17 ENSDART00000128742

chr9_+_42095220 1.11 ENSDART00000148317
ENSDART00000134431
poly(rC) binding protein 3
chr2_+_413370 1.03 ENSDART00000122138
myosin light chain kinase family, member 4a
chr17_-_4318393 0.95 ENSDART00000167995
ENSDART00000153824
N-ethylmaleimide-sensitive factor attachment protein, beta a
chr10_+_19554604 0.84 ENSDART00000063806
ATPase H+ transporting V1 subunit B2
chr5_+_37056818 0.83 ENSDART00000036760
tubulin polymerization-promoting protein family member 2
chr5_-_46273938 0.82 ENSDART00000080033
si:ch211-130m23.3
chr3_+_5575313 0.79 ENSDART00000134693
ENSDART00000101807
si:ch211-106h11.3
chr2_-_2020044 0.77 ENSDART00000024135
tubulin, beta 2A class IIa
chr10_+_15777064 0.74 ENSDART00000114483
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr2_+_59015878 0.71 ENSDART00000148816
ENSDART00000122795
si:ch1073-391i24.1
chr9_-_296169 0.71 ENSDART00000165228
kinesin family member 5A, a
chr15_+_24388782 0.70 ENSDART00000191661
ENSDART00000179995
ENSDART00000111226
seizure related 6 homolog b
chr6_-_17849786 0.69 ENSDART00000172709
regulatory associated protein of MTOR, complex 1
chr7_+_23907692 0.69 ENSDART00000045479
synaptotagmin IV
chr5_-_69482891 0.68 ENSDART00000109487

chr21_+_1382078 0.68 ENSDART00000188463
transcription factor 4
chr7_+_30867008 0.67 ENSDART00000193106
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr18_+_26895994 0.66 ENSDART00000098347
cholesterol 25-hydroxylase like 1, tandem duplicate 2
chr10_+_1638876 0.66 ENSDART00000184484
ENSDART00000060946
ENSDART00000181251
small G protein signaling modulator 1b
chr6_-_52156427 0.64 ENSDART00000082821
regulating synaptic membrane exocytosis 4
chr2_-_44282796 0.63 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
myelin protein zero
chr25_-_25736958 0.63 ENSDART00000166308
calcium and integrin binding family member 2
chr11_-_4235811 0.62 ENSDART00000121716
si:ch211-236d3.4
chr13_+_36764715 0.57 ENSDART00000111832
ENSDART00000085230
atlastin GTPase 1
chr13_+_4405282 0.57 ENSDART00000148280
proline rich 18
chr8_-_4618653 0.57 ENSDART00000025535
septin 5a
chr16_-_6821927 0.56 ENSDART00000149070
ENSDART00000149570
myelin basic protein b
chr15_+_47161917 0.55 ENSDART00000167860
growth associated protein 43
chr23_+_44732863 0.54 ENSDART00000160044
ENSDART00000172268
ATPase Na+/K+ transporting subunit beta 2a
chr20_-_53366137 0.53 ENSDART00000146001
WAS protein family, member 1
chr15_-_19250543 0.53 ENSDART00000092705
ENSDART00000138895
immunoglobulin superfamily, member 9Ba
chr20_+_20672163 0.52 ENSDART00000027758
reticulon 1b
chr16_+_53455638 0.50 ENSDART00000045792
ENSDART00000154189
RNA binding motif protein 24b
chr16_+_29303971 0.49 ENSDART00000087149
hyaluronan and proteoglycan link protein 2
chr7_+_69528850 0.48 ENSDART00000109507
Rap1 GTPase-GDP dissociation stimulator 1
chr11_-_38083397 0.48 ENSDART00000086516
ENSDART00000184033
kelch domain containing 8A
chr13_-_30028103 0.47 ENSDART00000183889
stearoyl-CoA desaturase b
chr22_-_38516922 0.47 ENSDART00000151257
ENSDART00000151785
kinesin light chain 4
chr25_+_35375848 0.47 ENSDART00000155721
anoctamin 3
chr7_-_6592142 0.45 ENSDART00000160137
potassium inwardly-rectifying channel, subfamily J, member 10a
chr11_+_25064519 0.45 ENSDART00000016181
ndrg family member 3a
chr10_+_15777258 0.43 ENSDART00000140511
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr18_-_14677936 0.43 ENSDART00000111995
si:dkey-238o13.4
chr17_+_51764310 0.42 ENSDART00000157171
si:ch211-168d23.3
chr11_+_35364445 0.41 ENSDART00000125766
CaM kinase-like vesicle-associated b
chr13_+_421231 0.41 ENSDART00000188212
ENSDART00000017854
leucine-rich, glioma inactivated 1a
chr10_+_37500234 0.40 ENSDART00000132096
ENSDART00000099473
musashi RNA-binding protein 2a
chr2_+_30916188 0.40 ENSDART00000137012
myomesin 1a (skelemin)
chr11_-_42554290 0.40 ENSDART00000130573
ATPase H+ transporting accessory protein 1 like a
chr3_-_16227490 0.39 ENSDART00000057159
ENSDART00000130611
ENSDART00000012835
calcium channel, voltage-dependent, beta 1 subunit
chr15_-_19128705 0.38 ENSDART00000152428
Rho GTPase activating protein 32a
chr21_+_34167178 0.38 ENSDART00000158308
transient receptor potential cation channel, subfamily C, member 5b
chr2_+_23222939 0.38 ENSDART00000026800
kinesin-associated protein 3b
chr11_+_1796426 0.37 ENSDART00000173330
low density lipoprotein receptor-related protein 1Aa
chr23_-_17470146 0.37 ENSDART00000002398
tripartite motif containing 101
chr10_+_39952995 0.37 ENSDART00000183077

chr16_-_45327616 0.36 ENSDART00000158733
si:dkey-33i11.1
chr1_-_55058795 0.35 ENSDART00000187293
pellino E3 ubiquitin protein ligase 1a
chr16_-_44399335 0.35 ENSDART00000165058
regulating synaptic membrane exocytosis 2a
chr14_-_24391424 0.35 ENSDART00000113376
ENSDART00000126894
family with sequence similarity 13, member B
chr12_+_49125510 0.35 ENSDART00000185804

chr3_-_16227683 0.33 ENSDART00000111707
calcium channel, voltage-dependent, beta 1 subunit
chr6_+_59967994 0.33 ENSDART00000050457
zgc:65895
chr17_-_43466317 0.32 ENSDART00000155313
heat shock protein 4 like
chr18_+_21122818 0.32 ENSDART00000060015
ENSDART00000060184
choline kinase alpha
chr22_-_881080 0.32 ENSDART00000185489
choline/ethanolamine phosphotransferase 1b
chr9_-_48397702 0.32 ENSDART00000147169
zgc:172182
chr4_-_22519516 0.31 ENSDART00000130409
ENSDART00000186258
ENSDART00000002851
ENSDART00000123801
lysine (K)-specific demethylase 7Aa
chr8_-_410728 0.31 ENSDART00000151255
tripartite motif containing 36
chr9_+_22375779 0.30 ENSDART00000183956
diacylglycerol kinase, gamma
chr6_+_34512313 0.30 ENSDART00000102554
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr16_+_23282655 0.30 ENSDART00000015956
ephrin-A1b
chr12_+_42436328 0.29 ENSDART00000167324
early B cell factor 3a
chr23_-_31645760 0.29 ENSDART00000035031
serum/glucocorticoid regulated kinase 1
chr3_+_26019426 0.28 ENSDART00000135389
ENSDART00000182411
FAD-dependent oxidoreductase domain containing 2
chr3_-_22829710 0.28 ENSDART00000055659
cytochrome b561
chr4_-_9557186 0.28 ENSDART00000150569
SH3 and multiple ankyrin repeat domains 3b
chr19_-_31686252 0.28 ENSDART00000131721
RHO family interacting cell polarization regulator 2
chr21_+_11415224 0.27 ENSDART00000049036
zgc:92275
chr19_+_342094 0.27 ENSDART00000151013
ENSDART00000187622
endosulfine alpha a
chr7_-_18601206 0.27 ENSDART00000111636
si:ch211-119e14.2
chr17_+_11507131 0.27 ENSDART00000013170
kinesin family member 26Ba
chr13_+_36622100 0.27 ENSDART00000133198
si:ch211-67f24.7
chr1_-_50710468 0.26 ENSDART00000080389
family with sequence similarity 13, member A
chr9_+_34425736 0.26 ENSDART00000135147
si:ch211-218d20.15
chr3_-_6767440 0.26 ENSDART00000156174
microtubule associated serine/threonine kinase 1b
chr5_+_66132394 0.26 ENSDART00000073892
zgc:114041
chr25_+_25737386 0.26 ENSDART00000108476
leucine rich repeat containing 61
chr1_+_11977426 0.26 ENSDART00000103399
tetraspanin 5b
chr12_+_47909026 0.25 ENSDART00000192472
thymus, brain and testes associated
chr25_-_11088839 0.25 ENSDART00000154748
synaptic vesicle glycoprotein 2Bb
chr8_-_1698155 0.25 ENSDART00000186159

chr6_+_34511886 0.25 ENSDART00000179450
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr23_-_41762797 0.25 ENSDART00000186564
serine/threonine kinase 35
chr7_+_38762043 0.25 ENSDART00000036461
Rho GTPase activating protein 1
chr4_-_5019113 0.24 ENSDART00000189321
ENSDART00000081990
striatin interacting protein 2
chr24_+_41931585 0.24 ENSDART00000130310
erythrocyte membrane protein band 4.1-like 3a
chr10_-_22831611 0.24 ENSDART00000160115
period circadian clock 1a
chr19_+_48111285 0.23 ENSDART00000169420
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2
chr3_-_40054615 0.23 ENSDART00000003511
ENSDART00000102540
ENSDART00000146121
lethal giant larvae homolog 1 (Drosophila)
chr7_-_12596727 0.22 ENSDART00000186413
ADAMTS-like 3
chr5_+_43458304 0.22 ENSDART00000051114
Rho-related BTB domain containing 2a
chr25_-_1720736 0.22 ENSDART00000097256
solute carrier family 6 member 13
chr5_-_54792239 0.22 ENSDART00000056213
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr17_+_35097024 0.22 ENSDART00000026152
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2a
chr20_-_43786515 0.22 ENSDART00000004601
lysosomal protein transmembrane 4 alpha
chr22_-_21676364 0.22 ENSDART00000183668
transducin like enhancer of split 2b
chr17_-_34963575 0.22 ENSDART00000145664
kinase D-interacting substrate 220a
chr15_+_47418565 0.21 ENSDART00000155709
ClpB homolog, mitochondrial AAA ATPase chaperonin
chr9_+_4378153 0.21 ENSDART00000191264
ENSDART00000182384
kalirin RhoGEF kinase a
chr19_+_8144556 0.21 ENSDART00000027274
ENSDART00000147218
ephrin-A3a
chr4_-_5018705 0.21 ENSDART00000154025
striatin interacting protein 2
chr1_+_45707219 0.21 ENSDART00000143363
si:ch211-214c7.4
chr23_-_41762956 0.20 ENSDART00000128302
serine/threonine kinase 35
chr5_+_38263240 0.20 ENSDART00000051231
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr6_-_15604417 0.20 ENSDART00000157817
leucine rich repeat (in FLII) interacting protein 1b
chr6_-_15604157 0.20 ENSDART00000141597
leucine rich repeat (in FLII) interacting protein 1b
chr18_-_3166726 0.20 ENSDART00000165002
aquaporin 11
chr4_-_5597802 0.19 ENSDART00000136229
vascular endothelial growth factor Ab
chr4_+_3980247 0.19 ENSDART00000049194
G protein-coupled receptor 37b
chr3_+_59117136 0.19 ENSDART00000182745
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr22_-_20924747 0.19 ENSDART00000185845
ENSDART00000179672
elongation factor RNA polymerase II
chr18_+_23249519 0.18 ENSDART00000005740
ENSDART00000147446
ENSDART00000124818
myocyte enhancer factor 2aa
chr14_+_33264303 0.18 ENSDART00000130680
ENSDART00000075187
PDZ domain containing 11
chr21_-_39670375 0.18 ENSDART00000151567
uncharacterized serine/threonine-protein kinase SgK494b
chr6_+_59854224 0.18 ENSDART00000083499
lysine (K)-specific demethylase 6A, like
chr7_-_64152087 0.18 ENSDART00000165234

chr7_-_69647988 0.17 ENSDART00000169943

chr20_-_54381034 0.17 ENSDART00000136779
ectonucleoside triphosphate diphosphohydrolase 5b
chr2_-_39675829 0.17 ENSDART00000147821
splA/ryanodine receptor domain and SOCS box containing 4a
chr8_+_1187928 0.17 ENSDART00000127252
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr24_-_36238054 0.16 ENSDART00000155725
transmembrane protein 241
chr1_+_51329069 0.16 ENSDART00000187729
ENSDART00000193246
ENSDART00000186753
ENSDART00000190206
microtubule associated serine/threonine kinase 1a
chr19_-_30420602 0.16 ENSDART00000144121
protein phosphatase 1, regulatory subunit 10
chr19_-_34011340 0.16 ENSDART00000172618
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr5_+_4006837 0.16 ENSDART00000138862
phosphatidylinositol glycan anchor biosynthesis, class W
chr23_-_32129569 0.16 ENSDART00000167761
ENSDART00000139569
zgc:92658
chr8_+_104114 0.16 ENSDART00000172101
synuclein, alpha interacting protein
chr3_-_47876427 0.16 ENSDART00000180844
ENSDART00000124480
adhesion G protein-coupled receptor L1a
chr1_+_45839927 0.16 ENSDART00000148086
ENSDART00000180413
ENSDART00000048191
ENSDART00000179047
mitogen-activated protein kinase kinase 7
chr12_+_6391243 0.16 ENSDART00000152765
protein kinase, cGMP-dependent, type Ib
chr18_+_507618 0.16 ENSDART00000159464
neural precursor cell expressed, developmentally down-regulated 4a
chr5_+_61657702 0.16 ENSDART00000134387
ENSDART00000171248
adaptor-related protein complex 2, beta 1 subunit
chr18_+_507835 0.16 ENSDART00000189701
neural precursor cell expressed, developmentally down-regulated 4a
chr21_+_21279159 0.16 ENSDART00000148346
inositol-trisphosphate 3-kinase Ca
chr1_+_42874410 0.16 ENSDART00000153506
catenin (cadherin-associated protein), alpha 2
chr20_+_572037 0.15 ENSDART00000028062
ENSDART00000152736
ENSDART00000031759
ENSDART00000162198
SET and MYND domain containing 2b
chr12_+_30046320 0.15 ENSDART00000179904
ENSDART00000153394
actin binding LIM protein 1b
chr22_-_20924564 0.15 ENSDART00000100642
ENSDART00000032770
elongation factor RNA polymerase II
chr19_+_27479563 0.15 ENSDART00000049368
ENSDART00000185426
alpha tubulin acetyltransferase 1
chr11_-_36341189 0.15 ENSDART00000159752
sortilin 1a
chr10_+_3299829 0.15 ENSDART00000183684
zgc:56235
chr11_-_36341028 0.15 ENSDART00000146093
sortilin 1a
chr23_-_27822920 0.15 ENSDART00000023094
activin A receptor type 1Ba
chr13_+_28618086 0.14 ENSDART00000087001
cyclin and CBS domain divalent metal cation transport mediator 2a
chr18_-_14917296 0.14 ENSDART00000098662
pannexin 2
chr2_+_37134281 0.14 ENSDART00000020135
peroxisomal biogenesis factor 19
chr16_+_30002605 0.14 ENSDART00000160555
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6E
chr2_-_32513538 0.14 ENSDART00000056640
ATP-binding cassette, sub-family F (GCN20), member 2a
chr7_-_19364813 0.14 ENSDART00000173977
netrin 4
chr25_-_31423493 0.14 ENSDART00000027661
myogenic differentiation 1
chr21_+_10794914 0.14 ENSDART00000084035
zinc finger protein 532
chr16_+_43077909 0.14 ENSDART00000014140
RUN domain containing 3b
chr10_+_6383270 0.14 ENSDART00000170548
zgc:114200
chr3_+_22578369 0.14 ENSDART00000187695
ENSDART00000182678
ENSDART00000112270
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2a
chr6_+_16031189 0.13 ENSDART00000015333
gastrulation brain homeobox 2
chr22_-_29586608 0.13 ENSDART00000059869
adrenoceptor alpha 2A
chr14_-_47849216 0.13 ENSDART00000192796
Rap guanine nucleotide exchange factor (GEF) 2
chr24_-_14712427 0.13 ENSDART00000176316
junctophilin 1a
chr12_+_11080776 0.13 ENSDART00000079336
retinoic acid receptor, alpha a
chr11_-_11301283 0.13 ENSDART00000113311
ENSDART00000180466
collagen, type IX, alpha 1a
chr10_+_4875262 0.13 ENSDART00000165942
paralemmin 2
chr23_-_43393589 0.13 ENSDART00000183592
zgc:174862
chr6_+_29693492 0.12 ENSDART00000114172
phosphodiesterase 6D, cGMP-specific, rod, delta
chr5_+_67812062 0.12 ENSDART00000158611
zgc:175280
chr23_-_41821825 0.12 ENSDART00000184725
si:ch73-302a13.2
chr16_-_20294236 0.12 ENSDART00000059623
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
chr10_-_42131408 0.12 ENSDART00000076693
STAM binding protein a
chr24_+_33622769 0.12 ENSDART00000079342
dynein, axonemal, heavy chain 5 like
chr17_-_44440832 0.12 ENSDART00000148786
exocyst complex component 5
chr22_+_34430310 0.12 ENSDART00000109860
adhesion molecule with Ig-like domain 3
chr14_+_12110020 0.11 ENSDART00000192462
potassium channel tetramerisation domain containing 12b
chr5_-_12031174 0.11 ENSDART00000159896
cytosolic arginine sensor for mTORC1 subunit 1
chr17_-_25831569 0.11 ENSDART00000148743
hedgehog acyltransferase
chr17_-_18898115 0.11 ENSDART00000028044
galactosylceramidase b
chr8_-_17167819 0.11 ENSDART00000135042
ENSDART00000143920
mitochondrial ribosomal protein S36
chr23_+_30730121 0.11 ENSDART00000134141
additional sex combs like transcriptional regulator 1
chr11_+_5499661 0.11 ENSDART00000027850
solute carrier family 35, member E1
chr9_-_1434484 0.10 ENSDART00000093412
oxysterol binding protein-like 6
chr1_-_7659870 0.10 ENSDART00000085203
ephrin-B2b
chr10_+_41668483 0.10 ENSDART00000127073
leucine rich repeat containing 75Bb
chr5_+_61658282 0.10 ENSDART00000188878
adaptor-related protein complex 2, beta 1 subunit
chr5_-_72136548 0.10 ENSDART00000007827
sepiapterin reductase a
chr20_-_36617313 0.10 ENSDART00000172395
ENSDART00000152856
enabled homolog (Drosophila)
chr23_-_10745288 0.10 ENSDART00000140745
ENSDART00000013768
eukaryotic translation initiation factor 4E family member 3
chr22_-_38224315 0.10 ENSDART00000165430
ENSDART00000140968
Hermansky-Pudlak syndrome 3

Network of associatons between targets according to the STRING database.

First level regulatory network of klf12a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.2 0.7 GO:1990535 neuron projection maintenance(GO:1990535)
0.2 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.5 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.3 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.1 0.4 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.5 GO:0036268 swimming(GO:0036268)
0.1 0.5 GO:1904861 excitatory synapse assembly(GO:1904861)
0.1 0.3 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.5 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 1.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.6 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.0 0.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.5 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.1 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.0 0.5 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.8 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.4 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.8 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.1 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.6 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.1 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.0 0.1 GO:0090467 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.0 0.1 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.7 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.6 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.0 1.2 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.2 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.2 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.0 0.7 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.1 GO:0001709 cell fate determination(GO:0001709)
0.0 0.2 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828)
0.0 1.8 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.1 GO:0021871 forebrain regionalization(GO:0021871)
0.0 0.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.6 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.7 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.3 GO:0060171 stereocilium membrane(GO:0060171)
0.1 1.2 GO:0043209 myelin sheath(GO:0043209)
0.1 0.4 GO:0001650 fibrillar center(GO:0001650)
0.1 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 1.0 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 1.8 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:0031430 M band(GO:0031430)
0.0 2.1 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.8 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.5 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0005844 polysome(GO:0005844)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.5 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.7 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.1 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 1.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 1.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 0.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.2 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.0 0.1 GO:1902388 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.0 0.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 1.0 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.0 GO:0000035 acyl binding(GO:0000035)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.8 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.0 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.7 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 0.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors