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PRJNA207719: Tissue specific transcriptome profiling

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Results for junba+junbb

Z-value: 2.84

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Transcription factors associated with junba+junbb

Gene Symbol Gene ID Gene Info
ENSDARG00000074378 JunB proto-oncogene, AP-1 transcription factor subunit a
ENSDARG00000104773 JunB proto-oncogene, AP-1 transcription factor subunit b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
junbbdr11_v1_chr3_-_7656059_76560590.474.3e-01Click!
junbadr11_v1_chr1_-_51734524_517345350.069.3e-01Click!

Activity profile of junba+junbb motif

Sorted Z-values of junba+junbb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_12385308 3.91 ENSDART00000080927
synaptosomal-associated protein, 25b
chr9_+_219124 3.63 ENSDART00000161484
mitogen-activated protein kinase kinase kinase 12
chr6_+_27667359 2.69 ENSDART00000159624
ENSDART00000049177
RAB6B, member RAS oncogene family a
chr19_+_24882845 2.58 ENSDART00000010580
si:ch211-195b13.1
chr3_-_36115339 2.49 ENSDART00000187406
ENSDART00000123505
ENSDART00000151775
RAB11 family interacting protein 4 (class II) a
chr20_+_34913069 2.46 ENSDART00000007584
synaptosomal-associated protein, 25a
chr18_+_16330025 2.45 ENSDART00000142353
neurotensin
chr1_-_38756870 2.20 ENSDART00000130324
ENSDART00000148404
glycoprotein M6Ab
chr2_-_42415902 2.11 ENSDART00000142489
solute carrier organic anion transporter family member 5A1b
chr10_-_39011514 2.09 ENSDART00000075123
Purkinje cell protein 4a
chr14_+_34486629 2.04 ENSDART00000131861
thymosin beta 2
chr2_-_11512819 2.03 ENSDART00000142013
proenkephalin a
chr18_+_21408794 2.01 ENSDART00000140161
N-terminal EF-hand calcium binding protein 2
chr3_-_49566364 2.00 ENSDART00000161507
zgc:153426
chr2_+_22694382 1.94 ENSDART00000139196
kinesin family member 1Ab
chr16_-_17207754 1.90 ENSDART00000063804
wu:fj39g12
chr1_-_22861348 1.88 ENSDART00000139412
si:dkey-92j12.6
chr11_+_25064519 1.81 ENSDART00000016181
ndrg family member 3a
chr25_-_23052707 1.78 ENSDART00000024633
dual specificity phosphatase 8a
chr8_+_23165749 1.78 ENSDART00000063057
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr17_+_29345606 1.71 ENSDART00000086164
potassium channel tetramerization domain containing 3
chr24_-_7632187 1.69 ENSDART00000041714
ATPase H+ transporting V0 subunit a1b
chr18_+_17663898 1.67 ENSDART00000021213
copine II
chr7_-_72605673 1.65 ENSDART00000123887
mitogen-activated protein kinase 8 interacting protein 1
chr9_+_42095220 1.65 ENSDART00000148317
ENSDART00000134431
poly(rC) binding protein 3
chr16_-_43026273 1.61 ENSDART00000156820
ENSDART00000189080
si:dkey-7j14.5
chr19_+_16222618 1.60 ENSDART00000137189
ENSDART00000169246
ENSDART00000190583
ENSDART00000189521
protein tyrosine phosphatase, receptor type, U, a
chr1_-_51606552 1.58 ENSDART00000130828
cannabinoid receptor interacting protein 1a
chr15_-_28200049 1.56 ENSDART00000004200
sterile alpha and TIR motif containing 1
chr8_+_23174137 1.55 ENSDART00000189470
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr14_-_7888748 1.55 ENSDART00000166293
protein phosphatase 3, catalytic subunit, beta isozyme
chr6_+_13933464 1.55 ENSDART00000109144
protein tyrosine phosphatase, receptor type, Nb
chr21_-_43606502 1.54 ENSDART00000151030
si:ch73-362m14.4
chr5_-_35301800 1.54 ENSDART00000085142
microtubule-associated protein 1B
chr3_+_32403758 1.53 ENSDART00000156982
si:ch211-195b15.8
chr1_+_49266886 1.52 ENSDART00000137179
calcyon neuron-specific vesicular protein
chr7_+_23907692 1.50 ENSDART00000045479
synaptotagmin IV
chr8_+_8845932 1.50 ENSDART00000112028
si:ch211-180f4.1
chr15_-_44512461 1.50 ENSDART00000155456
glutamate receptor, ionotropic, AMPA 4a
chr4_+_13733838 1.46 ENSDART00000067166
ENSDART00000133157
contactin 1b
chr20_-_34801181 1.46 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr8_+_29267093 1.46 ENSDART00000077647
glutamate receptor, ionotropic, delta 2
chr6_+_27146671 1.43 ENSDART00000156792
kinesin family member 1Aa
chr13_-_33398735 1.41 ENSDART00000182601
ENSDART00000103628
BTB (POZ) domain containing 6a
chr25_-_7686201 1.39 ENSDART00000157267
ENSDART00000155094
si:ch211-286c4.6
chr6_-_31348999 1.37 ENSDART00000153734
DnaJ (Hsp40) homolog, subfamily C, member 6
chr12_+_45200744 1.36 ENSDART00000098932
WW domain binding protein 2
chr11_-_7320211 1.36 ENSDART00000091664
adenomatosis polyposis coli 2
chr23_+_45584223 1.36 ENSDART00000149367
si:ch73-290k24.5
chr18_-_38087875 1.35 ENSDART00000111301
leucine zipper protein 2
chr15_-_163586 1.34 ENSDART00000163597
septin-4
chr23_-_637347 1.33 ENSDART00000132175
L1 cell adhesion molecule, paralog b
chr20_+_3108597 1.33 ENSDART00000133435
si:ch73-212j7.1
chr8_+_28065803 1.33 ENSDART00000178481
potassium voltage-gated channel, Shal-related subfamily, member 3
chr1_-_40227166 1.32 ENSDART00000146680
si:ch211-113e8.3
chr22_+_18786797 1.32 ENSDART00000141864
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr2_+_20332044 1.32 ENSDART00000112131
phospholipid phosphatase related 4a
chr7_-_39203799 1.31 ENSDART00000173727
cholinergic receptor, muscarinic 4a
chr22_+_11535131 1.30 ENSDART00000113930
neuropeptide B
chr12_-_19103490 1.30 ENSDART00000060561
cold shock domain containing C2, RNA binding a
chr3_-_5964557 1.29 ENSDART00000184738

chr9_+_11532025 1.28 ENSDART00000109037
cyclin-dependent kinase 5, regulatory subunit 2b (p39)
chr19_+_10396042 1.28 ENSDART00000028048
ENSDART00000151735
NECAP endocytosis associated 1
chr16_-_43025885 1.28 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
chr11_+_40649412 1.27 ENSDART00000043016
ENSDART00000134560
solute carrier family 45, member 1
chr8_+_8532407 1.27 ENSDART00000169276
ENSDART00000138993
glutamate receptor, metabotropic 6a
chr24_-_17444067 1.27 ENSDART00000155843
contactin associated protein like 2a
chr10_+_32683089 1.26 ENSDART00000063551
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr8_+_28066063 1.26 ENSDART00000078533
potassium voltage-gated channel, Shal-related subfamily, member 3
chr20_-_37522569 1.25 ENSDART00000177011
ENSDART00000058502
human immunodeficiency virus type I enhancer binding protein 2a
chr5_-_41560874 1.25 ENSDART00000136702
DnaJ (Hsp40) homolog, subfamily B, member 5
chr1_+_31864404 1.25 ENSDART00000075260
internexin neuronal intermediate filament protein, alpha b
chr20_+_27020201 1.25 ENSDART00000126919
ENSDART00000016014
chromogranin A
chr5_+_3501859 1.25 ENSDART00000080486
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1
chr15_-_12319065 1.23 ENSDART00000162973
ENSDART00000170543
FXYD domain containing ion transport regulator 6
chr10_+_34426571 1.23 ENSDART00000144529
neurobeachin a
chr12_-_30443562 1.22 ENSDART00000020769
adrenoceptor beta 1
chr17_+_24722646 1.22 ENSDART00000138356
mitochondrial fission regulator 1-like
chr25_+_16945348 1.21 ENSDART00000016591
fibroblast growth factor 6a
chr3_+_15271943 1.20 ENSDART00000141752
aspartate beta-hydroxylase domain containing 1
chr13_+_12175724 1.20 ENSDART00000166053
gamma-aminobutyric acid type A receptor gamma1 subunit
chr8_+_25959940 1.19 ENSDART00000143011
ENSDART00000140626
si:dkey-72l14.4
chr16_+_14029283 1.19 ENSDART00000146165
ENSDART00000132075
RUN and SH3 domain containing 1
chr24_+_34606966 1.19 ENSDART00000105477
leucine rich repeat transmembrane neuronal 2
chr8_+_39607466 1.18 ENSDART00000097427
musashi RNA-binding protein 1
chr21_-_24865454 1.17 ENSDART00000142907
immunoglobulin superfamily, member 9Bb
chr17_-_26721007 1.17 ENSDART00000034580
calmodulin 1a
chr2_+_25929619 1.17 ENSDART00000137746
solute carrier family 7, member 14a
chr2_-_27775236 1.16 ENSDART00000187983
zgc:123035
chr24_-_28711176 1.16 ENSDART00000105753
olfactomedin 3a
chr18_-_46063773 1.15 ENSDART00000078561
si:ch73-262h23.4
chr7_-_71434298 1.14 ENSDART00000180507
leucine-rich repeat LGI family, member 2a
chr19_+_45970692 1.13 ENSDART00000158781
si:ch211-153f2.7
chr9_-_31747106 1.12 ENSDART00000048469
ENSDART00000145204
ENSDART00000186889
sodium leak channel, non-selective
chr20_+_522457 1.11 ENSDART00000138585
5'-nucleotidase domain containing 1
chr7_-_48805181 1.11 ENSDART00000015884
milk fat globule-EGF factor 8 protein a
chr14_-_2050057 1.10 ENSDART00000112875
protocadherin beta 15
chr11_-_29623380 1.09 ENSDART00000162587
ENSDART00000193935
ENSDART00000191646
chromodomain helicase DNA binding protein 5
chr2_+_20331445 1.08 ENSDART00000186880
phospholipid phosphatase related 4a
chr13_+_15816573 1.08 ENSDART00000137061
kinesin light chain 1a
chr24_-_35767501 1.08 ENSDART00000105680
ENSDART00000042290
ENSDART00000166264
dystrobrevin, alpha
chr2_-_27774783 1.08 ENSDART00000161864
zgc:123035
chr25_-_31863374 1.08 ENSDART00000028338
secretory carrier membrane protein 5a
chr3_-_22214029 1.08 ENSDART00000154818
microtubule-associated protein tau b
chr12_+_7491690 1.07 ENSDART00000152564
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr23_+_2136344 1.06 ENSDART00000085290
ENSDART00000092757
cytoplasmic polyadenylation element binding protein 2
chr18_-_38088099 1.06 ENSDART00000146120
leucine zipper protein 2
chr21_+_22630297 1.06 ENSDART00000147175
si:dkeyp-69c1.7
chr17_+_956821 1.05 ENSDART00000082101
protein phosphatase 2, regulatory subunit B', gamma a
chr1_-_54947592 1.05 ENSDART00000129710
cartilage acidic protein 1a
chr10_-_22249444 1.05 ENSDART00000148831
fibroblast growth factor 11b
chr12_-_33972798 1.05 ENSDART00000105545
ADP-ribosylation factor-like 3
chr20_-_18736281 1.04 ENSDART00000142837
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr10_+_5689510 1.03 ENSDART00000183217
ENSDART00000172632
peptidylglycine alpha-amidating monooxygenase
chr10_-_45379831 1.03 ENSDART00000186205

chr5_-_23999777 1.03 ENSDART00000085969
MAP7 domain containing 2a
chr3_+_33367954 1.02 ENSDART00000103161
membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2)
chr6_-_51101834 1.02 ENSDART00000092493
protein tyrosine phosphatase, receptor type, t
chr10_+_15777258 1.02 ENSDART00000140511
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr22_-_7129631 1.01 ENSDART00000171359
acid-sensing (proton-gated) ion channel 1b
chr12_+_28298859 1.01 ENSDART00000183366

chr23_+_28582865 1.00 ENSDART00000020296
L1 cell adhesion molecule, paralog a
chr20_+_30490682 1.00 ENSDART00000184871
myelin transcription factor 1-like, a
chr18_+_10784730 1.00 ENSDART00000028938
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr17_-_21249651 1.00 ENSDART00000156580
ENSDART00000155221
heat shock protein 12A
chr14_-_1955257 0.99 ENSDART00000193254
protocadherin 2 gamma 5
chr19_-_874888 0.99 ENSDART00000007206
eomesodermin homolog a
chr23_-_28141419 0.98 ENSDART00000133039
tachykinin 3a
chr4_+_26496489 0.98 ENSDART00000160652
IQ motif and Sec7 domain 3a
chr8_+_39634114 0.97 ENSDART00000144293
musashi RNA-binding protein 1
chr17_+_12698532 0.97 ENSDART00000064509
ENSDART00000136830
stathmin-like 4, like
chr14_-_1958994 0.97 ENSDART00000161783
protocadherin 2 gamma 5
chr9_+_6997861 0.97 ENSDART00000190491
inositol polyphosphate-4-phosphatase type I Aa
chr20_+_19238382 0.97 ENSDART00000136757
fibronectin type III domain containing 4a
chr25_-_8030113 0.97 ENSDART00000104674
calcium/calmodulin-dependent protein kinase 1Db
chr14_-_1949277 0.96 ENSDART00000159435
protocadherin 2 gamma 5
chr15_+_36115955 0.96 ENSDART00000032702
somatostatin 1, tandem duplicate 2
chr21_+_25054420 0.95 ENSDART00000065132
zgc:171740
chr20_+_26095530 0.94 ENSDART00000139350
spectrin repeat containing, nuclear envelope 1a
chr9_+_6998082 0.94 ENSDART00000092480
ENSDART00000135576
ENSDART00000188884
inositol polyphosphate-4-phosphatase type I Aa
chr17_+_8184649 0.93 ENSDART00000091818
tubby like protein 4b
chr9_+_21535885 0.93 ENSDART00000141408
Rho guanine nucleotide exchange factor (GEF) 7a
chr10_+_15777064 0.93 ENSDART00000114483
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr5_-_46896541 0.93 ENSDART00000133240
EGF-like repeats and discoidin I-like domains 3a
chr10_-_7858553 0.92 ENSDART00000182010
inositol polyphosphate-5-phosphatase Ja
chr6_+_3004972 0.92 ENSDART00000186750
ENSDART00000183862
ENSDART00000191485
ENSDART00000171014
protein tyrosine phosphatase, receptor type, f, a
chr21_+_22630627 0.92 ENSDART00000193092
si:dkeyp-69c1.7
chr19_+_25649626 0.92 ENSDART00000146947
tachykinin 1
chr18_+_16749091 0.91 ENSDART00000061265
ring finger protein 141
chr24_-_22702017 0.90 ENSDART00000179403
catenin (cadherin-associated protein), delta 2a
chr13_+_13770980 0.90 ENSDART00000113089
solute carrier family 4, sodium borate transporter, member 11
chr19_-_10395683 0.90 ENSDART00000109488
zgc:194578
chr15_+_1372343 0.89 ENSDART00000152285
schwannomin interacting protein 1
chr25_-_31763897 0.88 ENSDART00000041740
ubiquitin-like 7a (bone marrow stromal cell-derived)
chr8_+_44714336 0.88 ENSDART00000145801
ELMO/CED-12 domain containing 3
chr2_+_21090317 0.88 ENSDART00000109568
ENSDART00000139633
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b
chr8_+_104114 0.87 ENSDART00000172101
synuclein, alpha interacting protein
chr1_+_49878000 0.87 ENSDART00000047876
lymphoid enhancer-binding factor 1
chr1_-_46924801 0.85 ENSDART00000142560
pyridoxal (pyridoxine, vitamin B6) kinase b
chr17_-_35881841 0.85 ENSDART00000110040
SRY (sex determining region Y)-box 11a
chr2_-_56635744 0.85 ENSDART00000167790
ENSDART00000168160
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b
chr4_-_72080351 0.85 ENSDART00000174925

chr7_-_40993456 0.84 ENSDART00000031700
engrailed homeobox 2a
chr7_-_51476276 0.84 ENSDART00000082464
NHS-like 2
chr8_+_25913787 0.84 ENSDART00000190257
ENSDART00000062515
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3H
chr13_+_4505079 0.84 ENSDART00000144312
phosphodiesterase 10A
chr22_+_12366516 0.84 ENSDART00000157802
R3H domain containing 1
chr6_+_33537267 0.84 ENSDART00000040334
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
chr12_+_33038757 0.83 ENSDART00000153146
RNA binding fox-1 homolog 3a
chr2_-_11912347 0.83 ENSDART00000023851
abhydrolase domain containing 3
chr14_+_5936996 0.83 ENSDART00000097144
ENSDART00000126777
potassium channel tetramerization domain containing 8
chr25_+_33849647 0.83 ENSDART00000121449
RAR-related orphan receptor A, paralog a
chr11_+_28476298 0.82 ENSDART00000122319
leucine rich repeat containing 38b
chr14_-_33454595 0.82 ENSDART00000109615
ENSDART00000173267
ENSDART00000185737
ENSDART00000190989
transmembrane protein 255A
chr14_-_2318590 0.81 ENSDART00000192735
protocadherin 2 alpha b 8
chr3_+_40576447 0.80 ENSDART00000083212
fascin actin-bundling protein 1a
chr21_+_13150937 0.80 ENSDART00000102251
spectrin alpha, non-erythrocytic 1
chr5_-_28679135 0.79 ENSDART00000193585
tenascin C
chr10_+_7563755 0.79 ENSDART00000165877
purine-rich element binding protein G
chr15_+_28685892 0.79 ENSDART00000155815
ENSDART00000060244
neuro-oncological ventral antigen 2
chr1_+_51312752 0.79 ENSDART00000063938
microtubule associated serine/threonine kinase 1a
chr23_+_19590006 0.78 ENSDART00000021231
sarcolemma associated protein b
chr13_+_12174937 0.78 ENSDART00000171683
gamma-aminobutyric acid type A receptor gamma1 subunit
chr19_-_10196370 0.76 ENSDART00000091707
D site albumin promoter binding protein a
chr19_-_30510930 0.76 ENSDART00000088760
ENSDART00000181043
BCL2 associated athanogene 6, like
chr9_+_21536122 0.76 ENSDART00000182266
Rho guanine nucleotide exchange factor (GEF) 7a
chr3_+_40315410 0.76 ENSDART00000083241
ENSDART00000132827
solute carrier family 29 (equilibrative nucleoside transporter), member 4
chr13_-_33822550 0.76 ENSDART00000143703
fibronectin leucine rich transmembrane 3
chr22_-_18746508 0.76 ENSDART00000003929
midnolin
chr2_-_5942355 0.76 ENSDART00000110469
transmembrane protein 125b
chr13_+_28854438 0.75 ENSDART00000193407
ENSDART00000189554

chr22_-_7168571 0.75 ENSDART00000165549
acid-sensing (proton-gated) ion channel 1b
chr13_+_24552254 0.74 ENSDART00000147907
lectin, galactoside-binding-like b
chr1_+_54908895 0.74 ENSDART00000145652
golgin A7 family, member Ba
chr23_-_24146591 0.74 ENSDART00000133269
Rho guanine nucleotide exchange factor (GEF) 19
chr17_+_17955063 0.74 ENSDART00000104999
coiled-coil domain containing 85C, a
chr7_+_21752168 0.74 ENSDART00000173641
lysine (K)-specific demethylase 6B, a
chr1_-_11291324 0.73 ENSDART00000091205
sidekick cell adhesion molecule 1b
chr2_+_9821757 0.73 ENSDART00000018408
ENSDART00000141227
ENSDART00000144681
ENSDART00000148227
annexin A13, like
chr3_+_31933893 0.72 ENSDART00000146509
ENSDART00000139644
lin-7 homolog B (C. elegans)

Network of associatons between targets according to the STRING database.

First level regulatory network of junba+junbb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0071435 potassium ion export(GO:0071435) potassium ion export across plasma membrane(GO:0097623)
0.5 1.6 GO:0019364 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.4 1.2 GO:0002792 negative regulation of peptide secretion(GO:0002792) negative regulation of peptide hormone secretion(GO:0090278)
0.4 1.9 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.3 4.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.3 1.7 GO:0010754 negative regulation of cGMP-mediated signaling(GO:0010754)
0.3 1.0 GO:0055109 invagination involved in gastrulation with mouth forming second(GO:0055109) morphogenesis of an epithelial fold(GO:0060571)
0.3 4.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.3 2.0 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.3 0.9 GO:0042823 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.3 1.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.3 0.8 GO:0014814 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.3 1.3 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.3 1.8 GO:0070207 protein homotrimerization(GO:0070207)
0.2 3.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.2 0.7 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.2 1.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.2 0.6 GO:0003403 optic vesicle formation(GO:0003403)
0.2 1.6 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.2 0.9 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.2 0.6 GO:1902410 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.2 0.9 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.2 0.9 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.2 1.0 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.2 0.7 GO:0071788 endoplasmic reticulum tubular network maintenance(GO:0071788)
0.2 0.7 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 1.1 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.2 0.6 GO:0090299 regulation of neural crest formation(GO:0090299)
0.2 0.8 GO:1901166 neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.2 0.6 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 0.9 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 1.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.6 GO:0098921 endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921)
0.1 0.4 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.7 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 1.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.9 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 1.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 6.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.1 GO:0072318 clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
0.1 1.7 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 2.9 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 0.9 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 2.4 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.4 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.1 0.3 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.1 2.3 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.4 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 1.5 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.9 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.1 0.6 GO:1901739 regulation of myoblast fusion(GO:1901739)
0.1 0.6 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 1.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 1.3 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.4 GO:0072116 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 0.5 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.1 0.4 GO:0055071 manganese ion homeostasis(GO:0055071)
0.1 2.5 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 0.6 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 1.6 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 2.0 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.1 1.5 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 1.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 2.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 1.0 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.9 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.8 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 0.2 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 1.2 GO:0032418 lysosome localization(GO:0032418)
0.1 0.3 GO:0035627 ceramide transport(GO:0035627)
0.1 1.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.6 GO:0008216 spermidine metabolic process(GO:0008216)
0.1 0.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 1.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.7 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.1 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.9 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.4 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.1 0.5 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) single-organism membrane invagination(GO:1902534)
0.1 0.3 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1 0.5 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 0.5 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.3 GO:0021588 cerebellum formation(GO:0021588)
0.1 3.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.3 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 2.4 GO:0032456 endocytic recycling(GO:0032456)
0.1 1.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.2 GO:0010259 multicellular organism aging(GO:0010259)
0.1 1.3 GO:0007631 feeding behavior(GO:0007631)
0.1 0.4 GO:0001839 neural plate morphogenesis(GO:0001839)
0.1 0.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.4 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:0061437 renal system vasculature development(GO:0061437) renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439) kidney vasculature development(GO:0061440) glomerulus vasculature development(GO:0072012) glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.0 0.4 GO:0030656 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.2 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.0 0.2 GO:0090104 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.0 0.4 GO:0021794 thalamus development(GO:0021794)
0.0 0.3 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.2 GO:0018199 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.0 0.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 1.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.4 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 3.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.9 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.0 0.4 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.6 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.4 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.1 GO:0009838 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 1.3 GO:0000266 mitochondrial fission(GO:0000266)
0.0 1.2 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.2 GO:1902765 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.0 0.4 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.3 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0031112 positive regulation of microtubule polymerization or depolymerization(GO:0031112) positive regulation of microtubule polymerization(GO:0031116)
0.0 1.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.2 GO:0006921 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 2.0 GO:0007416 synapse assembly(GO:0007416)
0.0 0.2 GO:0072574 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.0 0.9 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.4 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.8 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.0 1.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.7 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.1 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.6 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.9 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 6.6 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.1 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144) negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.7 GO:0051904 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.1 GO:0090008 pancreas morphogenesis(GO:0061113) hypoblast development(GO:0090008)
0.0 2.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 4.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0045471 response to ethanol(GO:0045471)
0.0 0.0 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 2.5 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.2 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.0 1.8 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543) cellular response to fibroblast growth factor stimulus(GO:0044344) response to fibroblast growth factor(GO:0071774)
0.0 0.7 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.0 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 4.1 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.5 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.3 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.1 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.2 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.4 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 0.1 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.1 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222)
0.0 1.1 GO:0001819 positive regulation of cytokine production(GO:0001819)
0.0 0.6 GO:0072089 stem cell proliferation(GO:0072089)
0.0 0.3 GO:0035141 medial fin morphogenesis(GO:0035141)
0.0 0.4 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.5 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.8 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.3 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.4 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 2.8 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 0.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.4 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.9 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 1.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.3 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.5 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 1.1 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 0.4 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.4 GO:0034250 positive regulation of cellular amide metabolic process(GO:0034250) positive regulation of translation(GO:0045727)
0.0 0.1 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.0 0.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.7 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.2 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.5 GO:0046488 phosphatidylinositol metabolic process(GO:0046488)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.4 4.5 GO:0044295 axonal growth cone(GO:0044295)
0.3 0.8 GO:0033268 node of Ranvier(GO:0033268)
0.3 1.5 GO:0005955 calcineurin complex(GO:0005955)
0.3 1.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 1.2 GO:0005883 neurofilament(GO:0005883)
0.2 1.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 0.7 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 0.7 GO:0060171 stereocilium membrane(GO:0060171)
0.2 1.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 1.3 GO:0033010 paranodal junction(GO:0033010)
0.1 1.2 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.6 GO:0008091 spectrin(GO:0008091)
0.1 0.8 GO:0071818 BAT3 complex(GO:0071818)
0.1 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 1.5 GO:0031209 SCAR complex(GO:0031209)
0.1 1.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 3.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 2.0 GO:0032590 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.1 1.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 8.3 GO:0043025 neuronal cell body(GO:0043025)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.5 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.2 GO:0034657 GID complex(GO:0034657)
0.0 0.2 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 1.2 GO:0030426 growth cone(GO:0030426)
0.0 4.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.4 GO:0034464 BBSome(GO:0034464)
0.0 0.4 GO:0072487 MSL complex(GO:0072487)
0.0 2.2 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.8 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 1.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.9 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 1.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 6.5 GO:0036477 somatodendritic compartment(GO:0036477)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0038039 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 7.9 GO:0043005 neuron projection(GO:0043005)
0.0 1.5 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.9 GO:0001726 ruffle(GO:0001726)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.4 3.6 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.4 1.8 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.3 1.7 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.3 0.9 GO:0031834 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.3 4.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 1.1 GO:0071889 14-3-3 protein binding(GO:0071889)
0.3 0.8 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.3 1.9 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.3 1.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.3 1.5 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 1.6 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.2 1.6 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.9 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.2 0.7 GO:0097016 L27 domain binding(GO:0097016)
0.2 1.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 2.0 GO:0031628 opioid receptor binding(GO:0031628)
0.2 6.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.0 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.1 1.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 1.0 GO:0008506 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.5 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 1.0 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 3.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.3 GO:0035620 ceramide transporter activity(GO:0035620) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388)
0.1 1.9 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.9 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 1.7 GO:0051117 ATPase binding(GO:0051117)
0.1 1.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.4 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 3.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.6 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 1.8 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 1.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.8 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.1 0.4 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 1.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 2.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 2.3 GO:0031267 small GTPase binding(GO:0031267)
0.1 1.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.7 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.4 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 2.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 1.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.3 GO:0005009 insulin-activated receptor activity(GO:0005009) insulin receptor substrate binding(GO:0043560)
0.1 2.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.6 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.1 0.8 GO:0070628 proteasome binding(GO:0070628)
0.1 0.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.3 GO:0008126 acetylesterase activity(GO:0008126)
0.0 2.8 GO:0005178 integrin binding(GO:0005178)
0.0 2.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 1.7 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 1.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.3 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.6 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 3.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.1 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 1.5 GO:0044325 ion channel binding(GO:0044325)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 2.0 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.4 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 1.6 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 3.1 GO:0005179 hormone activity(GO:0005179)
0.0 1.1 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:1901612 cardiolipin binding(GO:1901612)
0.0 4.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.6 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.5 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.1 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.6 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 2.0 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.1 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 1.0 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.5 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.0 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 4.0 GO:0015631 tubulin binding(GO:0015631)
0.0 2.7 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.7 PID REELIN PATHWAY Reelin signaling pathway
0.1 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 1.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.3 PID INSULIN PATHWAY Insulin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 0.6 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 1.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 4.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.9 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events