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PRJNA207719: Tissue specific transcriptome profiling
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Results for junba+junbb
Z-value: 2.84
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Transcription factors associated with junba+junbb
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| junbb | dr11_v1_chr3_-_7656059_7656059 | 0.47 | 4.3e-01 | Click! |
| junba | dr11_v1_chr1_-_51734524_51734535 | 0.06 | 9.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_-_12385308 Show fit | 3.91 |
ENSDART00000080927
|
synaptosomal-associated protein, 25b |
|
| chr9_+_219124 Show fit | 3.63 |
ENSDART00000161484
|
mitogen-activated protein kinase kinase kinase 12 |
|
| chr6_+_27667359 Show fit | 2.69 |
ENSDART00000159624
ENSDART00000049177 |
RAB6B, member RAS oncogene family a |
|
| chr19_+_24882845 Show fit | 2.58 |
ENSDART00000010580
|
si:ch211-195b13.1 |
|
| chr3_-_36115339 Show fit | 2.49 |
ENSDART00000187406
ENSDART00000123505 ENSDART00000151775 |
RAB11 family interacting protein 4 (class II) a |
|
| chr20_+_34913069 Show fit | 2.46 |
ENSDART00000007584
|
synaptosomal-associated protein, 25a |
|
| chr18_+_16330025 Show fit | 2.45 |
ENSDART00000142353
|
neurotensin |
|
| chr1_-_38756870 Show fit | 2.20 |
ENSDART00000130324
ENSDART00000148404 |
glycoprotein M6Ab |
|
| chr2_-_42415902 Show fit | 2.11 |
ENSDART00000142489
|
solute carrier organic anion transporter family member 5A1b |
|
| chr10_-_39011514 Show fit | 2.09 |
ENSDART00000075123
|
Purkinje cell protein 4a |
Network of associatons between targets according to the STRING database.
First level regulatory network of junba+junbb
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.6 | GO:0006470 | protein dephosphorylation(GO:0006470) |
| 0.1 | 6.0 | GO:0007019 | microtubule depolymerization(GO:0007019) |
| 0.3 | 4.7 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.0 | 4.7 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 4.1 | GO:0018105 | peptidyl-serine phosphorylation(GO:0018105) |
| 0.3 | 4.0 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.2 | 3.6 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.1 | 3.2 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.0 | 3.1 | GO:0046839 | phospholipid dephosphorylation(GO:0046839) |
| 0.1 | 2.9 | GO:0021555 | midbrain-hindbrain boundary morphogenesis(GO:0021555) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.3 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.0 | 7.9 | GO:0043005 | neuron projection(GO:0043005) |
| 0.0 | 6.5 | GO:0036477 | somatodendritic compartment(GO:0036477) |
| 1.1 | 6.4 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.4 | 4.5 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 4.2 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.1 | 3.0 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 2.2 | GO:0014069 | postsynaptic density(GO:0014069) |
| 0.0 | 2.1 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.1 | 2.0 | GO:0032590 | neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.1 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 4.9 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.3 | 4.0 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 0.0 | 4.0 | GO:0015631 | tubulin binding(GO:0015631) |
| 0.0 | 3.9 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.4 | 3.6 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 0.1 | 3.5 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 3.1 | GO:0042577 | lipid phosphatase activity(GO:0042577) |
| 0.0 | 3.1 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 2.8 | GO:0005178 | integrin binding(GO:0005178) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.8 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.2 | 2.2 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.1 | 1.7 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 1.7 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 1.5 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.4 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.1 | 1.2 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 1.0 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.9 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 0.8 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.6 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.1 | 3.4 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.1 | 2.3 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 1.8 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.1 | 1.7 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.1 | 1.4 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 1.2 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.1 | 1.1 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 1.0 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.9 | REACTOME CIRCADIAN CLOCK | Genes involved in Circadian Clock |