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PRJNA207719: Tissue specific transcriptome profiling

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Results for irx5a+irx5b_irx3a+irx3b

Z-value: 1.55

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Transcription factors associated with irx5a+irx5b_irx3a+irx3b

Gene Symbol Gene ID Gene Info
ENSDARG00000034043 iroquois homeobox 5a
ENSDARG00000074070 iroquois homeobox 5b
ENSDARG00000031138 iroquois homeobox 3b
ENSDARG00000101076 iroquois homeobox 3a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irx3bdr11_v1_chr25_-_36492779_36492779-0.941.7e-02Click!
irx5bdr11_v1_chr25_+_36152215_36152215-0.731.6e-01Click!
irx3adr11_v1_chr7_+_36041509_36041509-0.286.5e-01Click!
irx5adr11_v1_chr7_-_35710263_35710263-0.227.2e-01Click!

Activity profile of irx5a+irx5b_irx3a+irx3b motif

Sorted Z-values of irx5a+irx5b_irx3a+irx3b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_50147948 1.12 ENSDART00000149010
haptoglobin
chr11_-_45185792 0.86 ENSDART00000171328
si:dkey-93h22.7
chr3_-_32956808 0.71 ENSDART00000183902
caspase 6, apoptosis-related cysteine peptidase, like 1
chr1_-_7951002 0.70 ENSDART00000138187
si:dkey-79f11.8
chr7_+_56577522 0.62 ENSDART00000149130
ENSDART00000149624
haptoglobin
chr7_+_56577906 0.59 ENSDART00000184023
haptoglobin
chr17_-_5352924 0.56 ENSDART00000167275
SPT3 homolog, SAGA and STAGA complex component
chr20_+_34029820 0.55 ENSDART00000143901
ENSDART00000134305
proteoglycan 4b
chr2_-_13333932 0.53 ENSDART00000150238
ENSDART00000168258
si:dkey-185p13.1
vacuolar protein sorting 4b homolog B (S. cerevisiae)
chr16_-_42186093 0.53 ENSDART00000076030
fibrillarin
chr19_-_8748571 0.52 ENSDART00000031173
ribosomal protein S27, isoform 1
chr8_-_20914829 0.50 ENSDART00000025356
HAUS augmin-like complex, subunit 5
chr3_-_34100700 0.49 ENSDART00000151628
immunoglobulin heavy variable 6-1
chr24_-_27419198 0.49 ENSDART00000141124
chemokine (C-C motif) ligand 34b, duplicate 4
chr17_-_4395373 0.49 ENSDART00000015923
kelch-like family member 10a
chr23_-_44574059 0.48 ENSDART00000123007
si:ch73-160p18.3
chr11_+_14284866 0.48 ENSDART00000163729
si:ch211-262i1.3
chr6_+_41144155 0.48 ENSDART00000191395
ENSDART00000143577
solute carrier family 6 member 22, tandem duplicate 2
chr24_-_24983047 0.46 ENSDART00000066631
solute carrier family 51, alpha subunit
chr16_+_42018367 0.46 ENSDART00000058613
Fli-1 proto-oncogene, ETS transcription factor b
chr3_-_16784280 0.45 ENSDART00000137108
ENSDART00000137276
si:dkey-30j10.5
chr8_+_3405612 0.45 ENSDART00000163437
zgc:112433
chr18_-_49286381 0.45 ENSDART00000174248
ENSDART00000174038
si:zfos-464b6.2
chr8_-_4760723 0.45 ENSDART00000064201
CDC45 cell division cycle 45 homolog (S. cerevisiae)
chr2_+_17055069 0.45 ENSDART00000115078
thrombopoietin
chr10_-_42237304 0.45 ENSDART00000140341
transcription factor 7 like 1a
chr3_-_33970190 0.44 ENSDART00000151238
ighj2-5
chr5_+_24087035 0.44 ENSDART00000183644
tumor protein p53
chr10_-_6976645 0.43 ENSDART00000123312
SH2 domain containing 4A
chr7_+_34587081 0.43 ENSDART00000173817
formin homology 2 domain containing 1
chr6_-_7438584 0.43 ENSDART00000053776
FK506 binding protein 11
chr9_-_5337923 0.43 ENSDART00000017939
TNF superfamily member 13b
chr11_+_13224281 0.43 ENSDART00000102557
ENSDART00000178706
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
chr19_-_48336535 0.42 ENSDART00000162752
si:ch73-359m17.6
chr14_+_45471642 0.42 ENSDART00000126979
ENSDART00000172952
ENSDART00000173284
UBX domain protein 1
chr22_+_6293563 0.42 ENSDART00000063416
ribonuclease like 2
chr22_-_1079773 0.41 ENSDART00000136668
si:ch1073-15f12.3
chr11_+_24716837 0.40 ENSDART00000145217
zgc:153953
chr3_-_32541033 0.40 ENSDART00000151476
ENSDART00000055324
reticulocalbin 3, EF-hand calcium binding domain
chr22_-_26353916 0.39 ENSDART00000077958
calpain 2, (m/II) large subunit b
chr13_+_2908764 0.39 ENSDART00000162362
wu:fj16a03
chr1_+_53945934 0.39 ENSDART00000052838
actin, alpha 1a, skeletal muscle
chr12_+_20693743 0.39 ENSDART00000153023
ENSDART00000153370
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 2
chr24_-_23758003 0.39 ENSDART00000178085
Danio rerio minichromosome maintenance domain containing 2 (mcmdc2), mRNA.
chr22_+_19478140 0.39 ENSDART00000135291
ENSDART00000136576
si:dkey-78l4.8
chr25_-_3867990 0.38 ENSDART00000075663
calcium release activated channel regulator 2B
chr13_+_13578552 0.38 ENSDART00000101673
forkhead box I2
chr6_-_54826061 0.37 ENSDART00000149982
troponin I type 1b (skeletal, slow)
chr3_-_33970431 0.37 ENSDART00000151313
ighj2-4
chr23_-_7594723 0.37 ENSDART00000115298
pleiomorphic adenoma gene-like 2
chr2_+_36608387 0.37 ENSDART00000159541
p21 protein (Cdc42/Rac)-activated kinase 2a
chr14_-_36799280 0.37 ENSDART00000168615
ring finger protein 130
chr24_-_25098719 0.37 ENSDART00000193651
pleckstrin homology-like domain, family B, member 2b
chr5_+_45677781 0.36 ENSDART00000163120
ENSDART00000126537
group-specific component (vitamin D binding protein)
chr6_-_54180516 0.36 ENSDART00000149945
ribosomal protein S10
chr25_-_29072162 0.36 ENSDART00000169269
AT rich interactive domain 3B (BRIGHT-like)
chr5_-_58996324 0.36 ENSDART00000033923
MIS12 kinetochore complex component
chr7_+_9922607 0.36 ENSDART00000184532
ENSDART00000113396
ceramide synthase 3a
chr25_-_34281411 0.36 ENSDART00000189932
glucosaminyl (N-acetyl) transferase 3, mucin type
chr19_-_7115229 0.36 ENSDART00000001930
proteasome subunit beta 13a
chr18_+_22109379 0.36 ENSDART00000147230
zgc:158868
chr7_-_71758307 0.35 ENSDART00000161067
ENSDART00000165253
myomesin 1b
chr16_-_53259409 0.35 ENSDART00000157080
si:ch211-269k10.4
chr22_-_22340688 0.35 ENSDART00000105597
si:ch211-129c21.1
chr13_-_34683370 0.34 ENSDART00000113661
kinesin family member 16Bb
chr16_-_15263099 0.34 ENSDART00000125691
syntrophin, basic 1
chr17_+_22102791 0.34 ENSDART00000047772
mal, T cell differentiation protein
chr16_-_47381519 0.34 ENSDART00000032188
ENSDART00000150136
si:dkey-256h2.1
chr19_-_11237125 0.34 ENSDART00000163921
signal sequence receptor, beta
chr5_+_43782267 0.34 ENSDART00000130355
nitric oxide synthase 2a, inducible
chr13_+_22717366 0.34 ENSDART00000134122
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr25_+_13205878 0.34 ENSDART00000162319
ENSDART00000162283
si:ch211-147m6.2
chr10_+_8629275 0.34 ENSDART00000129643
apelin receptor b
chr22_-_23666504 0.33 ENSDART00000158665
complement factor H
chr7_-_21928826 0.33 ENSDART00000088043
si:dkey-85k7.11
chr11_+_42474694 0.33 ENSDART00000056048
ENSDART00000184710
si:ch1073-165f9.2
chr22_+_10781894 0.33 ENSDART00000081183
ectodermal-neural cortex 3
chr4_-_12997587 0.33 ENSDART00000140532
si:dkey-6a5.3
chr17_+_30587333 0.33 ENSDART00000156500
NHS-like 1a
chr16_+_29516098 0.32 ENSDART00000174895
cathepsin S, ortholog 2, tandem duplicate 2
chr3_-_50136424 0.32 ENSDART00000188843
bloodthirsty-related gene family, member 2
chr15_-_21132480 0.31 ENSDART00000078734
ENSDART00000157481
alpha-2-macroglobulin-like
chr13_-_41908583 0.31 ENSDART00000136515
inositol polyphosphate multikinase a
chr7_-_6357952 0.31 ENSDART00000173197
zgc:165555
chr8_-_36475328 0.31 ENSDART00000048448
si:busm1-266f07.2
chr5_+_66170479 0.31 ENSDART00000172117
glycine dehydrogenase (decarboxylating)
chr23_+_46157638 0.31 ENSDART00000076048
bloodthirsty-related gene family, member 32
chr3_+_25999477 0.31 ENSDART00000024316
minichromosome maintenance complex component 5
chr9_-_9415000 0.30 ENSDART00000146210
si:ch211-214p13.9
chr16_+_53259521 0.30 ENSDART00000155461
si:ch211-269k10.5
chr3_+_19336286 0.30 ENSDART00000111528
KRI1 homolog
chr20_+_54299419 0.30 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
chr1_-_56032619 0.30 ENSDART00000143793
complement component c3a, duplicate 4
chr4_+_7391400 0.30 ENSDART00000169111
ENSDART00000186395
troponin I4a
chr16_-_16522013 0.30 ENSDART00000160602
neurobeachin-like 2
chr14_+_21106444 0.30 ENSDART00000075744
ENSDART00000132363
aldolase b, fructose-bisphosphate
chr20_+_10723292 0.30 ENSDART00000152805
si:ch211-182e10.4
chr15_-_563877 0.30 ENSDART00000128032
cerebellin 18
chr23_+_45027263 0.30 ENSDART00000058364
high mobility group box 2b
chr4_-_20313810 0.29 ENSDART00000136350
decapping mRNA 1B
chr22_+_37874691 0.29 ENSDART00000028565
alpha-2-HS-glycoprotein 1
chr23_+_32044410 0.29 ENSDART00000048628
myosin light chain kinase 2
chr3_+_24618012 0.29 ENSDART00000111997
zgc:171506
chr9_+_24088062 0.29 ENSDART00000126198
leucine rich repeat (in FLII) interacting protein 1a
chr14_+_15620640 0.29 ENSDART00000188867
si:dkey-203a12.9
chr20_-_33566640 0.29 ENSDART00000159729
si:dkey-65b13.9
chr24_-_27473771 0.29 ENSDART00000139874
CX chemokine ligand 34b, duplicate 11
chr3_+_21200763 0.29 ENSDART00000067841
zgc:112038
chr20_+_24448007 0.29 ENSDART00000139866
si:dkey-273g18.1
chr9_-_14055959 0.29 ENSDART00000146675
fer-1-like family member 6
chr12_-_30549022 0.29 ENSDART00000102474
zgc:158404
chr9_-_34396264 0.29 ENSDART00000045754
growth hormone regulated TBC protein 1b
chr23_-_36313431 0.28 ENSDART00000125860
nuclear factor, erythroid 2
chr11_-_42134968 0.28 ENSDART00000187115

chr8_-_24252933 0.28 ENSDART00000057624
zgc:110353
chr10_+_45345574 0.28 ENSDART00000166085
peptidylprolyl isomerase Ab (cyclophilin A)
chr15_-_29573267 0.28 ENSDART00000099947
SAM domain, SH3 domain and nuclear localisation signals 1a
chr16_-_45230084 0.28 ENSDART00000184652
si:dkey-33i11.4
chr21_-_22648007 0.28 ENSDART00000121788
grass carp reovirus (GCRV)-induced gene 2l
chr4_-_7869731 0.28 ENSDART00000067339
minichromosome maintenance 10 replication initiation factor
chr4_-_8043839 0.28 ENSDART00000190047
ENSDART00000057567
si:ch211-240l19.5
chr22_+_9069081 0.27 ENSDART00000187842

chr4_-_78020361 0.27 ENSDART00000159559
ENSDART00000162341
pepsinogen 3, group I (pepsinogen A)
chr4_+_76755294 0.27 ENSDART00000142339
membrane-spanning 4-domains, subfamily A, member 17A.12
chr15_-_21155641 0.27 ENSDART00000061098
ENSDART00000046443
si:dkey-105h12.2
chr1_+_26667872 0.27 ENSDART00000152803
ENSDART00000152144
ENSDART00000152785
ENSDART00000152393
hemogen
chr10_+_8656417 0.27 ENSDART00000123131
phorbol-12-myristate-13-acetate-induced protein 1
chr1_-_23293261 0.27 ENSDART00000122648
UDP-glucose 6-dehydrogenase
chr1_-_55116453 0.27 ENSDART00000142348
SERTA domain containing 2a
chr4_+_62341346 0.27 ENSDART00000160601
zinc finger protein 1079
chr1_+_53919110 0.27 ENSDART00000020680
nucleoporin 133
chr21_-_20832482 0.27 ENSDART00000191928
complement component 6
chr16_+_23984179 0.27 ENSDART00000175879
apolipoprotein C-II
chr5_+_1933131 0.27 ENSDART00000061693
si:ch73-55i23.1
chr21_+_30084823 0.27 ENSDART00000154573
proline-rich basic protein 1
chr20_-_487783 0.27 ENSDART00000162218
collagen, type X, alpha 1b
chr15_+_12377887 0.26 ENSDART00000170769
interleukin 10 receptor, alpha
chr8_-_1219815 0.26 ENSDART00000016800
ENSDART00000149969
zinc finger protein 367
chr21_-_41838284 0.26 ENSDART00000141067
chaperonin containing TCP1, subunit 6A (zeta 1)
chr9_+_29985010 0.26 ENSDART00000020743
cms1 ribosomal small subunit homolog (yeast)
chr9_+_426392 0.26 ENSDART00000172515
basic leucine zipper and W2 domains 1b
chr5_+_29831235 0.26 ENSDART00000109660
F11 receptor, tandem duplicate 1
chr9_+_20853894 0.26 ENSDART00000003648
WD repeat domain 3
chr23_+_4890693 0.26 ENSDART00000023537
troponin C type 1a (slow)
chr8_+_28695914 0.26 ENSDART00000033386
osteoclast stimulatory transmembrane protein
chr13_+_13681681 0.26 ENSDART00000057825
complement factor D (adipsin)
chr24_-_4765740 0.26 ENSDART00000121576
carboxypeptidase B1 (tissue)
chr7_+_19600262 0.25 ENSDART00000007310
zgc:171731
chr7_-_60831082 0.25 ENSDART00000073654
ENSDART00000136999
pyruvate carboxylase b
chr6_-_54180699 0.25 ENSDART00000045901
ribosomal protein S10
chr15_+_42560354 0.25 ENSDART00000059484
zgc:110333
chr22_-_347424 0.25 ENSDART00000067633
NECAP endocytosis associated 2
chr16_-_44709832 0.25 ENSDART00000156784
si:ch211-151m7.6
chr14_+_10567104 0.25 ENSDART00000160723
G protein-coupled receptor 174
chr4_+_18843015 0.25 ENSDART00000152086
ENSDART00000066977
ENSDART00000132567
BCL2 interacting killer
chr12_-_31484677 0.24 ENSDART00000066578
tectorin beta
chr14_+_21222287 0.24 ENSDART00000159905
si:ch211-175m2.4
chr23_+_19701587 0.24 ENSDART00000104425
deoxyribonuclease I-like 1
chr4_-_17725008 0.24 ENSDART00000016658
choline phosphotransferase 1
chr1_+_1904419 0.24 ENSDART00000142874
si:ch211-132g1.4
chr16_+_25184207 0.24 ENSDART00000147584
hematopoietic cell signal transducer
chr10_+_40700311 0.24 ENSDART00000157650
ENSDART00000138342
trace amine associated receptor 19n
chr14_+_1007169 0.24 ENSDART00000172676
coagulation factor VIII, procoagulant component
chr20_+_54034512 0.24 ENSDART00000173226
si:dkey-241l7.2
chr13_-_43149063 0.24 ENSDART00000099601
V-set immunoregulatory receptor
chr16_-_13388821 0.24 ENSDART00000144062
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr8_+_19356072 0.24 ENSDART00000063272
macrophage expressed 1, tandem duplicate 2
chr3_-_32925476 0.24 ENSDART00000189673
amine oxidase, copper containing 2
chr19_+_7115223 0.24 ENSDART00000001359
proteasome subunit beta 12
chr16_-_35975254 0.23 ENSDART00000167537
eva-1 homolog Ba (C. elegans)
chr20_+_23440632 0.23 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
chr14_-_10617127 0.23 ENSDART00000154299
si:dkey-92i17.2
chr20_-_25518488 0.23 ENSDART00000186993
cytochrome P450, family 2, subfamily N, polypeptide 13
chr18_-_40773413 0.23 ENSDART00000133797
vasodilator stimulated phosphoprotein b
chr5_+_19261687 0.23 ENSDART00000139401
ATPase phospholipid transporting 8B5a
chr24_-_37640705 0.23 ENSDART00000066583
zgc:112496
chr6_+_612594 0.23 ENSDART00000150903
kynureninase
chr14_+_21107032 0.23 ENSDART00000138319
ENSDART00000139103
ENSDART00000184735
aldolase b, fructose-bisphosphate
chr3_-_50147160 0.23 ENSDART00000191341
bloodthirsty-related gene family, member 2
chr2_-_127945 0.23 ENSDART00000056453
insulin-like growth factor binding protein 1b
chr5_-_35159379 0.23 ENSDART00000144105
FCH domain only 2
chr17_+_24684778 0.23 ENSDART00000146309
ENSDART00000082237
zinc finger protein 593
chr23_+_45845423 0.23 ENSDART00000183404
lamin L3
chr10_+_8401929 0.23 ENSDART00000059028
hydrogen voltage-gated channel 1
chr21_-_34972872 0.22 ENSDART00000023838
lipase, member Ia
chr2_-_42109575 0.22 ENSDART00000075551
alcohol dehydrogenase, iron containing, 1
chr6_-_15641686 0.22 ENSDART00000135583
melanophilin a
chr20_+_54018005 0.22 ENSDART00000123026
ENSDART00000152894
si:dkey-241l7.5
chr15_-_39971756 0.22 ENSDART00000063789
ribosomal protein S5
chr9_+_21358941 0.22 ENSDART00000147619
ENSDART00000059402
EEF1A lysine methyltransferase 1
chr24_-_25244637 0.22 ENSDART00000153798
HERV-H LTR-associating 2b, tandem duplicate 2
chr1_+_40156908 0.22 ENSDART00000138886
si:ch211-113e8.9
chr15_+_21202820 0.22 ENSDART00000154036
si:dkey-52d15.2
chr5_+_22370167 0.22 ENSDART00000145163
si:dkey-27p18.7
chr13_-_4223955 0.22 ENSDART00000113060
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr10_+_28428222 0.22 ENSDART00000135003
si:ch211-222e20.4
chr21_+_3796196 0.22 ENSDART00000146754
SPOUT domain containing methyltransferase 1
chr2_+_22496973 0.22 ENSDART00000159638
leucine rich repeat containing 8 VRAC subunit Da
chr13_-_41901225 0.22 ENSDART00000167582
inositol polyphosphate multikinase a
chr22_+_25672155 0.21 ENSDART00000087769
si:ch211-250e5.2

Network of associatons between targets according to the STRING database.

First level regulatory network of irx5a+irx5b_irx3a+irx3b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.1 0.4 GO:0032197 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.1 0.4 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.4 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.4 GO:0001782 B cell homeostasis(GO:0001782) positive regulation of B cell proliferation(GO:0030890)
0.1 0.3 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.1 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.3 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.1 0.4 GO:0042182 ketone catabolic process(GO:0042182)
0.1 0.3 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.4 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.3 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 0.7 GO:0031126 snoRNA 3'-end processing(GO:0031126)
0.1 0.3 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 0.2 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.1 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.1 0.4 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 0.3 GO:0008594 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 1.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.2 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.1 0.1 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.1 0.3 GO:0030826 regulation of cGMP metabolic process(GO:0030823) positive regulation of cGMP metabolic process(GO:0030825) regulation of cGMP biosynthetic process(GO:0030826) positive regulation of cGMP biosynthetic process(GO:0030828) regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.2 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.2 GO:1903961 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.1 0.2 GO:0010898 regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898) positive regulation of lipid catabolic process(GO:0050996)
0.0 0.3 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.4 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.3 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.0 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.2 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.3 GO:0003188 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0009268 response to pH(GO:0009268) cellular response to pH(GO:0071467)
0.0 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:0048785 hatching gland development(GO:0048785)
0.0 0.2 GO:0031652 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364) pore complex assembly(GO:0046931) disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.2 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.1 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.0 0.3 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 0.1 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.3 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.3 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.6 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.6 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.1 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:0006168 adenine salvage(GO:0006168)
0.0 0.1 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:0061015 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.0 0.1 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.0 0.1 GO:0003400 regulation of COPII vesicle coating(GO:0003400) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.0 0.2 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.5 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0061511 centriole elongation(GO:0061511)
0.0 0.4 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.2 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0034434 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0 0.4 GO:0051492 regulation of stress fiber assembly(GO:0051492)
0.0 0.1 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.0 0.2 GO:1901185 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.4 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.2 GO:0045444 fat cell differentiation(GO:0045444)
0.0 0.2 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.1 GO:0003250 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.0 0.1 GO:0007344 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.0 0.2 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0034087 establishment of mitotic sister chromatid cohesion(GO:0034087) establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.1 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0090224 regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.0 0.2 GO:0061157 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.8 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 0.1 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.0 0.4 GO:0019835 cytolysis(GO:0019835)
0.0 0.3 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.0 0.3 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.4 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.1 GO:0072574 hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.0 0.1 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.2 GO:0046348 chitin catabolic process(GO:0006032) amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.3 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.0 GO:0021730 trigeminal sensory nucleus development(GO:0021730)
0.0 0.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.2 GO:0033198 response to ATP(GO:0033198)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.3 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.1 GO:0031448 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.0 0.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.3 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.0 0.3 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.0 0.2 GO:0030168 platelet activation(GO:0030168)
0.0 0.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.5 GO:0007596 blood coagulation(GO:0007596)
0.0 0.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.3 GO:0051180 vitamin transport(GO:0051180)
0.0 0.0 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.2 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.0 0.1 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.4 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.3 GO:0061702 inflammasome complex(GO:0061702)
0.1 0.5 GO:0030914 STAGA complex(GO:0030914)
0.1 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.2 GO:0044279 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.4 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.1 0.3 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.2 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.0 0.2 GO:0005880 nuclear microtubule(GO:0005880)
0.0 0.1 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.0 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 1.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0055087 Ski complex(GO:0055087)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.6 GO:0030686 90S preribosome(GO:0030686)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784)
0.0 0.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.4 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0005861 troponin complex(GO:0005861)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2 0.6 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.4 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.1 0.3 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 0.4 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.6 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1 0.3 GO:0060182 apelin receptor activity(GO:0060182)
0.1 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.2 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.2 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 1.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.5 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.0 0.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 0.6 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.2 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.5 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.3 GO:0016594 glycine binding(GO:0016594)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.4 GO:0030546 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.0 0.1 GO:0005542 folic acid binding(GO:0005542)
0.0 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 0.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 3.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.3 GO:0042379 chemokine activity(GO:0008009) chemokine receptor binding(GO:0042379)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.1 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.0 GO:0030623 U5 snRNA binding(GO:0030623)
0.0 0.0 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) excitatory extracellular ligand-gated ion channel activity(GO:0005231) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 2.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0008832 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.0 0.1 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 0.0 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.0 0.2 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0017022 myosin binding(GO:0017022)
0.0 0.4 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:1903924 estradiol binding(GO:1903924)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.1 GO:0005537 mannose binding(GO:0005537)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.2 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.1 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks