Project

PRJNA207719: Tissue specific transcriptome profiling

Navigation
Downloads

Results for irf4a+irf4b

Z-value: 1.57

Motif logo

logo of

Transcription factors associated with irf4a+irf4b

Gene Symbol Gene ID Gene Info
irf4a
ENSDARG00000006560 interferon regulatory factor 4a
irf4b
ENSDARG00000055374 interferon regulatory factor 4b
irf4b
ENSDARG00000115381 interferon regulatory factor 4b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irf4bdr11_v1_chr20_+_26556174_265561740.903.8e-02Click!
irf4adr11_v1_chr2_-_879800_8798000.829.0e-02Click!

Activity profile of irf4a+irf4b motif

Sorted Z-values of irf4a+irf4b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_7110617 2.22 ENSDART00000104838
psmb8a
proteasome subunit beta 8A
chr1_-_7582859 1.68 ENSDART00000110696
mxb
myxovirus (influenza) resistance B
chr21_+_45626136 1.44 ENSDART00000158742
irf1b
interferon regulatory factor 1b
chr17_-_22552678 1.21 ENSDART00000079401
si:ch211-125o16.4
si:ch211-125o16.4
chr7_-_19614916 1.14 ENSDART00000169029
zgc:194655
zgc:194655
chr1_-_7570181 1.12 ENSDART00000103588
mxa
myxovirus (influenza) resistance A
chr14_-_33585809 1.09 ENSDART00000023540
sash3
SAM and SH3 domain containing 3
chr7_+_19615056 1.07 ENSDART00000124752
ENSDART00000190297
si:ch211-212k18.15
si:ch211-212k18.15
chr4_-_26107841 1.00 ENSDART00000172012
si:ch211-244b2.4
si:ch211-244b2.4
chr16_+_48753664 0.98 ENSDART00000155148
si:ch73-31d8.2
si:ch73-31d8.2
chr9_-_32837860 0.97 ENSDART00000142227
mxe
myxovirus (influenza virus) resistance E
chr2_-_37140423 0.95 ENSDART00000144220
tspan37
tetraspanin 37
chr4_-_12795436 0.93 ENSDART00000131026
ENSDART00000075127
b2m
beta-2-microglobulin
chr1_+_38153944 0.91 ENSDART00000135666
galnt7
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr15_+_34069746 0.90 ENSDART00000163513
arl4aa
ADP-ribosylation factor-like 4aa
chr8_-_27687095 0.87 ENSDART00000086946
mov10b.1
Moloney leukemia virus 10b, tandem duplicate 1
chr16_+_29492937 0.85 ENSDART00000011497
ctsk
cathepsin K
chr15_-_17071328 0.84 ENSDART00000122617
si:ch211-24o10.6
si:ch211-24o10.6
chr11_+_10984293 0.83 ENSDART00000065933
itgb6
integrin, beta 6
chr17_+_35362851 0.83 ENSDART00000137659
cmpk2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr2_-_13333932 0.80 ENSDART00000150238
ENSDART00000168258
si:dkey-185p13.1
vps4b
si:dkey-185p13.1
vacuolar protein sorting 4b homolog B (S. cerevisiae)
chr9_+_23765587 0.80 ENSDART00000145120
si:ch211-219a4.3
si:ch211-219a4.3
chr4_-_17669881 0.79 ENSDART00000066997
dram1
DNA-damage regulated autophagy modulator 1
chr9_-_23765480 0.79 ENSDART00000027212
si:ch211-219a4.6
si:ch211-219a4.6
chr4_-_12795030 0.74 ENSDART00000150427
b2m
beta-2-microglobulin
chr22_-_17474583 0.72 ENSDART00000148027
si:ch211-197g15.8
si:ch211-197g15.8
chr10_+_8101729 0.72 ENSDART00000138875
ENSDART00000123447
ENSDART00000185333
pstpip2
proline-serine-threonine phosphatase interacting protein 2
chr19_-_15420678 0.72 ENSDART00000151454
ENSDART00000027697
serinc2
serine incorporator 2
chr7_+_19482877 0.69 ENSDART00000077868
si:ch211-212k18.7
si:ch211-212k18.7
chr19_+_791538 0.69 ENSDART00000146554
ENSDART00000138406
tmem79a
transmembrane protein 79a
chr3_+_25191467 0.68 ENSDART00000156956
ENSDART00000154799
il2rb
interleukin 2 receptor, beta
chr23_-_30045661 0.66 ENSDART00000122239
ENSDART00000103480
ccdc187
coiled-coil domain containing 187
chr12_-_23658888 0.65 ENSDART00000088319
map3k8
mitogen-activated protein kinase kinase kinase 8
chr10_+_110868 0.63 ENSDART00000135572
ENSDART00000190467
ENSDART00000056672
pigp
phosphatidylinositol glycan anchor biosynthesis, class P
chr7_+_19483277 0.58 ENSDART00000173750
si:ch211-212k18.7
si:ch211-212k18.7
chr19_-_42462491 0.56 ENSDART00000131715
psmb4
proteasome subunit beta 4
chr16_+_19637384 0.53 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
macc1
metastasis associated in colon cancer 1
chr18_+_44532370 0.52 ENSDART00000086952
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr5_-_69716501 0.52 ENSDART00000158956
mob1a
MOB kinase activator 1A
chr13_+_17694845 0.52 ENSDART00000079778
ifit8
interferon-induced protein with tetratricopeptide repeats 8
chr18_+_44532883 0.50 ENSDART00000121994
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr4_+_68562464 0.50 ENSDART00000192954
BX548011.4

chr20_-_35012093 0.49 ENSDART00000062761
cnstb
consortin, connexin sorting protein b
chr13_-_50200042 0.49 ENSDART00000074230
pkz
protein kinase containing Z-DNA binding domains
chr12_+_36109507 0.48 ENSDART00000175409
map2k6
mitogen-activated protein kinase kinase 6
chr10_+_28160265 0.47 ENSDART00000022484
rnft1
ring finger protein, transmembrane 1
chr5_+_13385837 0.46 ENSDART00000191190
ccl19a.1
chemokine (C-C motif) ligand 19a, tandem duplicate 1
chr25_-_37489917 0.44 ENSDART00000160688
psma1
proteasome subunit alpha 1
chr4_+_11464255 0.43 ENSDART00000008584
gdi2
GDP dissociation inhibitor 2
chr1_-_49530615 0.43 ENSDART00000113315
si:ch211-281g13.5
si:ch211-281g13.5
chr7_-_26579465 0.43 ENSDART00000173820
si:dkey-62k3.6
si:dkey-62k3.6
chr5_+_28260158 0.40 ENSDART00000181434
ncaph
non-SMC condensin I complex, subunit H
chr15_-_40175894 0.40 ENSDART00000156632
si:ch211-281l24.3
si:ch211-281l24.3
chr3_-_29941357 0.39 ENSDART00000147732
ENSDART00000137973
ENSDART00000103523
grna
granulin a
chr10_-_17550931 0.39 ENSDART00000145077
ska1
spindle and kinetochore associated complex subunit 1
chr2_+_42708674 0.39 ENSDART00000141989
ENSDART00000005767
ftr11
finTRIM family, member 11
chr16_+_46497149 0.39 ENSDART00000135151
ENSDART00000058324
rpz4
rapunzel 4
chr13_+_22476742 0.39 ENSDART00000078759
ENSDART00000130101
ENSDART00000137220
ENSDART00000133065
ENSDART00000147348
ldb3a
LIM domain binding 3a
chr15_-_1835189 0.38 ENSDART00000154369
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr21_+_25793970 0.38 ENSDART00000101217
CLDN4 (1 of many)
zgc:136892
chr11_-_6206520 0.38 ENSDART00000150199
ENSDART00000148246
ENSDART00000019440
pole4
polymerase (DNA-directed), epsilon 4, accessory subunit
chr18_+_44532199 0.37 ENSDART00000135386
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr22_-_17474781 0.36 ENSDART00000186817
si:ch211-197g15.8
si:ch211-197g15.8
chr13_-_50200348 0.35 ENSDART00000038391
pkz
protein kinase containing Z-DNA binding domains
chr22_-_30999000 0.35 ENSDART00000109841
ssuh2.3
ssu-2 homolog, tandem duplicate 3
chr21_+_11535304 0.34 ENSDART00000158901
ENSDART00000081600
cd8b
cd8 beta
chr8_+_45361775 0.34 ENSDART00000015193
chmp4bb
charged multivesicular body protein 4Bb
chr9_+_34089156 0.34 ENSDART00000000005
ccdc80
coiled-coil domain containing 80
chr18_+_17624295 0.33 ENSDART00000151865
ENSDART00000190408
ENSDART00000189204
ENSDART00000188894
ENSDART00000033762
ENSDART00000193471
nlrc5
NLR family, CARD domain containing 5
chr12_-_27242498 0.33 ENSDART00000152609
ENSDART00000152170
si:dkey-11c5.11
si:dkey-11c5.11
chr15_-_21702317 0.32 ENSDART00000155824
IL4I1
si:dkey-40g16.6
chr22_+_19365220 0.32 ENSDART00000132781
ENSDART00000135672
ENSDART00000153630
si:dkey-21e2.12
si:dkey-21e2.12
chr12_+_36109071 0.31 ENSDART00000171268
map2k6
mitogen-activated protein kinase kinase 6
chr15_-_41749364 0.30 ENSDART00000155464
ftr73
finTRIM family, member 73
chr25_-_483808 0.28 ENSDART00000104720
si:ch1073-385f13.3
si:ch1073-385f13.3
chr7_-_20464133 0.28 ENSDART00000078192
cnpy4
canopy4
chr11_-_42472941 0.28 ENSDART00000166624
arf4b
ADP-ribosylation factor 4b
chr25_+_28862660 0.28 ENSDART00000154681
si:ch211-106e7.2
si:ch211-106e7.2
chr6_-_40466861 0.23 ENSDART00000062724
crbn
cereblon
chr23_-_29553430 0.22 ENSDART00000157773
ENSDART00000126384
ube4b
ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)
chr23_-_35396845 0.22 ENSDART00000142038
ENSDART00000049373
ENSDART00000181978
ENSDART00000171357
cmtr1
cap methyltransferase 1
chr18_+_44532668 0.22 ENSDART00000140672
st14a
suppression of tumorigenicity 14 (colon carcinoma) a
chr6_-_18400548 0.22 ENSDART00000179797
ENSDART00000164891
trim25
tripartite motif containing 25
chr24_-_3407507 0.22 ENSDART00000132648
nck1b
NCK adaptor protein 1b
chr8_+_20157798 0.21 ENSDART00000124809
acsbg2
acyl-CoA synthetase bubblegum family member 2
chr21_-_40049642 0.20 ENSDART00000124416
med31
mediator complex subunit 31
chr7_-_34192834 0.19 ENSDART00000125131
smad6a
SMAD family member 6a
chr22_-_8692305 0.19 ENSDART00000181602
CR450686.4

chr5_+_69716458 0.19 ENSDART00000159594
mthfd2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr25_-_774350 0.18 ENSDART00000166321
ENSDART00000160386
IRAK4
interleukin 1 receptor associated kinase 4
chr15_-_41734639 0.18 ENSDART00000154230
ENSDART00000167443
ftr90
finTRIM family, member 90
chr25_-_3034668 0.18 ENSDART00000053405
scamp2
secretory carrier membrane protein 2
chr13_+_24263049 0.18 ENSDART00000135992
ENSDART00000088005
abcb10
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr12_-_35936329 0.17 ENSDART00000166634
rnf213b
ring finger protein 213b
chr12_+_48319221 0.17 ENSDART00000126362
anapc16
anaphase promoting complex subunit 16
chr9_+_51147764 0.17 ENSDART00000188480
ifih1
interferon induced with helicase C domain 1
chr11_-_575786 0.17 ENSDART00000019997
mkrn2
makorin, ring finger protein, 2
chr2_-_26620803 0.16 ENSDART00000003946
ENSDART00000126826
tmem59
transmembrane protein 59
chr3_+_36127287 0.14 ENSDART00000058605
ENSDART00000182500
scpep1
serine carboxypeptidase 1
chr9_-_23747264 0.14 ENSDART00000141461
ENSDART00000010311
ndufa10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10
chr9_+_51147380 0.14 ENSDART00000003913
ifih1
interferon induced with helicase C domain 1
chr9_+_42269059 0.14 ENSDART00000113435
si:dkey-10c21.1
si:dkey-10c21.1
chr17_-_23603263 0.13 ENSDART00000079559
ifit16
interferon-induced protein with tetratricopeptide repeats 16
chr5_+_21922534 0.13 ENSDART00000148092
si:ch73-92i20.1
si:ch73-92i20.1
chr4_-_6373735 0.13 ENSDART00000140100
MDFIC
si:ch73-156e19.1
chr20_-_38525467 0.13 ENSDART00000061417
si:ch211-245h14.1
si:ch211-245h14.1
chr3_-_26171668 0.12 ENSDART00000113890
rabep2
rabaptin, RAB GTPase binding effector protein 2
chr24_-_11467004 0.11 ENSDART00000144316
pxdc1b
PX domain containing 1b
chr14_+_33329420 0.10 ENSDART00000171090
ENSDART00000164062
sowahd
sosondowah ankyrin repeat domain family d
chr2_-_43739740 0.10 ENSDART00000113849
kif5ba
kinesin family member 5B, a
chr21_-_22543611 0.10 ENSDART00000177084
myo5b
myosin VB
chr2_+_37975026 0.10 ENSDART00000034802
si:rp71-1g18.13
si:rp71-1g18.13
chr24_-_11467549 0.09 ENSDART00000082264
pxdc1b
PX domain containing 1b
chr20_-_3911546 0.09 ENSDART00000169787
cnksr3
cnksr family member 3
chr23_-_29553691 0.09 ENSDART00000053804
ube4b
ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)
chr1_-_35924495 0.08 ENSDART00000184424
smad1
SMAD family member 1
chr6_-_10728057 0.08 ENSDART00000002247
sp3b
Sp3b transcription factor
chr22_-_10605045 0.07 ENSDART00000184812
bap1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr9_+_23003208 0.07 ENSDART00000021060
eaf2
ELL associated factor 2
chr7_+_17908235 0.07 ENSDART00000077113
mta2
metastasis associated 1 family, member 2
chr19_-_19871211 0.07 ENSDART00000170980
evx1
even-skipped homeobox 1
chr9_-_30576522 0.07 ENSDART00000101085
morc3a
MORC family CW-type zinc finger 3a
chr2_-_55797318 0.06 ENSDART00000158147
calr3b
calreticulin 3b
chr25_+_16646113 0.06 ENSDART00000110426
cecr2
cat eye syndrome chromosome region, candidate 2
chr18_-_24988645 0.05 ENSDART00000136434
ENSDART00000085735
chd2
chromodomain helicase DNA binding protein 2
chr12_-_28975705 0.05 ENSDART00000129173
znf646
zinc finger protein 646
chr21_+_21010786 0.04 ENSDART00000079692
ndr1
nodal-related 1
chr5_+_66063807 0.04 ENSDART00000122405
jak2b
Janus kinase 2b
chr8_-_51340773 0.03 ENSDART00000060633
kansl3
KAT8 regulatory NSL complex subunit 3
chr1_-_36771712 0.03 ENSDART00000148386
prmt9
protein arginine methyltransferase 9
chr17_+_43895158 0.02 ENSDART00000111123
msh4
mutS homolog 4
chr4_+_54948890 0.02 ENSDART00000166873
si:dkey-56m15.7
si:dkey-56m15.7
chr22_+_38914983 0.01 ENSDART00000085701
senp5
SUMO1/sentrin specific peptidase 5
chr2_+_2818645 0.01 ENSDART00000163587
rock1
Rho-associated, coiled-coil containing protein kinase 1
chr7_+_19738665 0.00 ENSDART00000089333
tkfc
triokinase/FMN cyclase

Network of associatons between targets according to the STRING database.

First level regulatory network of irf4a+irf4b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.2 3.8 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.2 0.9 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.2 0.5 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 2.0 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.1 1.7 GO:0050688 regulation of defense response to virus(GO:0050688)
0.1 0.3 GO:0044878 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.1 3.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.5 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.1 0.6 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.1 0.3 GO:0032608 interferon-beta production(GO:0032608) regulation of interferon-beta production(GO:0032648) positive regulation of interferon-beta production(GO:0032728)
0.0 0.4 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.1 GO:0070589 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 0.2 GO:0080009 7-methylguanosine mRNA capping(GO:0006370) mRNA methylation(GO:0080009)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.8 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 1.4 GO:0051607 defense response to virus(GO:0051607)
0.0 0.8 GO:0042476 odontogenesis(GO:0042476)
0.0 0.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 1.1 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.8 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971) axo-dendritic protein transport(GO:0099640)
0.0 0.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.8 GO:0060348 bone development(GO:0060348)
0.0 1.7 GO:0016485 protein processing(GO:0016485)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 0.8 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.2 1.2 GO:0043034 costamere(GO:0043034)
0.2 3.8 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 3.2 GO:0005839 proteasome core complex(GO:0005839)
0.1 0.4 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.4 GO:0000796 condensin complex(GO:0000796)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.9 GO:0043186 P granule(GO:0043186)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.3 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.3 0.8 GO:0009041 uridylate kinase activity(GO:0009041)
0.2 0.8 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 2.8 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.4 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.1 GO:0031386 protein tag(GO:0031386)
0.1 0.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0016405 CoA-ligase activity(GO:0016405)
0.0 0.8 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 0.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 0.8 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.8 PID CXCR4 PATHWAY CXCR4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.8 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions