Project

PRJNA207719: Tissue specific transcriptome profiling

Navigation
Downloads

Results for irf1a

Z-value: 2.11

Motif logo

Transcription factors associated with irf1a

Gene Symbol Gene ID Gene Info
ENSDARG00000043492 interferon regulatory factor 1a

Activity profile of irf1a motif

Sorted Z-values of irf1a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_7115229 3.84 ENSDART00000001930
proteasome subunit beta 13a
chr5_+_13373593 3.75 ENSDART00000051668
ENSDART00000183883
chemokine (C-C motif) ligand 19a, tandem duplicate 2
chr13_+_13681681 2.88 ENSDART00000057825
complement factor D (adipsin)
chr19_+_7115223 2.83 ENSDART00000001359
proteasome subunit beta 12
chr11_-_20096018 2.50 ENSDART00000030420
opioid growth factor receptor-like 2
chr1_-_52431220 2.03 ENSDART00000111256
zgc:194101
chr15_-_29162193 1.97 ENSDART00000138449
ENSDART00000099885
XIAP associated factor 1
chr1_-_52447364 1.95 ENSDART00000140740
si:ch211-217k17.10
chr23_+_642395 1.78 ENSDART00000186995
interferon regulatory factor 10
chr23_+_642001 1.73 ENSDART00000030643
ENSDART00000124850
interferon regulatory factor 10
chr14_+_36889893 1.70 ENSDART00000124159
si:ch211-132p1.3
chr1_-_8000428 1.68 ENSDART00000133098
si:dkey-79f11.5
chr24_+_12945803 1.61 ENSDART00000005105
proteasome activator subunit 1
chr3_+_1942219 1.48 ENSDART00000114520
zgc:165583
chr22_-_10580194 1.47 ENSDART00000105848
si:dkey-42i9.7
chr5_-_825920 1.45 ENSDART00000126982
zgc:158463
chr8_-_36469117 1.44 ENSDART00000111240
major histocompatibility complex class II DAB gene
chr15_-_47929455 1.44 ENSDART00000064462
proteasome subunit alpha 6, like
chr21_+_8533533 1.42 ENSDART00000077924

chr13_+_27328098 1.36 ENSDART00000037585
Mab-21 domain containing 1
chr22_-_10158038 1.32 ENSDART00000047444
RanBP-type and C3HC4-type zinc finger containing 1
chr9_+_25330905 1.29 ENSDART00000101470
integral membrane protein 2Bb
chr21_-_22673758 1.29 ENSDART00000164910
grass carp reovirus (GCRV)-induced gene 2i
chr19_+_7938121 1.26 ENSDART00000140053
ENSDART00000146649
si:dkey-266f7.5
chr6_+_52947699 1.26 ENSDART00000180913
ubiquitin-like modifier activating enzyme 7
chr16_+_29514473 1.26 ENSDART00000034102
cathepsin S, ortholog 2, tandem duplicate 2
chr3_+_29941777 1.24 ENSDART00000113889
interferon-induced protein 35
chr20_+_26683933 1.21 ENSDART00000139852
ENSDART00000077751
forkhead box Q1b
chr4_+_5842433 1.20 ENSDART00000124085
ENSDART00000179848
ubiquitin specific peptidase 18
chr5_-_57723929 1.20 ENSDART00000144237
grass carp reovirus (GCRV)-induced gene 2p
chr22_-_36926342 1.16 ENSDART00000151804
si:dkey-37m8.11
chr10_-_4375190 1.16 ENSDART00000016102

chr1_-_25177086 1.15 ENSDART00000144711
ENSDART00000177225
transmembrane protein 154
chr23_+_36063599 1.15 ENSDART00000103147
homeobox C12a
chr1_-_7930679 1.09 ENSDART00000146090
si:dkey-79f11.10
chr19_+_23296616 1.08 ENSDART00000134567
immunity-related GTPase family, f1
chr2_-_42035250 1.05 ENSDART00000056460
ENSDART00000140788
guanylate binding protein 1
chr4_-_12795030 1.05 ENSDART00000150427
beta-2-microglobulin
chr17_+_35362851 1.03 ENSDART00000137659
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr1_-_47161996 1.03 ENSDART00000053153
major histocompatibility complex class I ZBA
chr19_+_7124337 1.03 ENSDART00000031380
transporter associated with antigen processing, subunit type a
chr19_-_325584 1.02 ENSDART00000134266
glycerol-3-phosphate dehydrogenase 1c
chr22_-_18164671 1.01 ENSDART00000014057
regulatory factor X-associated ankyrin-containing protein
chr7_+_19600262 1.00 ENSDART00000007310
zgc:171731
chr6_+_52947186 0.96 ENSDART00000155831
ubiquitin-like modifier activating enzyme 7
chr11_+_1575435 0.96 ENSDART00000155713
ENSDART00000156562
si:dkey-40c23.1
chr22_-_18164835 0.95 ENSDART00000143189
regulatory factor X-associated ankyrin-containing protein
chr3_-_48980319 0.89 ENSDART00000165319
finTRIM family, member 42
chr22_-_17459587 0.88 ENSDART00000142267
si:ch211-197g15.10
chr13_+_47810211 0.84 ENSDART00000122964
zmp:0000001006
chr9_-_18215644 0.81 ENSDART00000145876
epithelial stromal interaction 1
chr22_-_15693085 0.81 ENSDART00000141861
si:ch1073-396h14.1
chr23_+_46183410 0.80 ENSDART00000167596
ENSDART00000151149
ENSDART00000150896
bloodthirsty-related gene family, member 31
chr4_-_17669881 0.80 ENSDART00000066997
DNA-damage regulated autophagy modulator 1
chr16_-_51271962 0.79 ENSDART00000164021
ENSDART00000046420
serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1
chr17_-_35361322 0.79 ENSDART00000019617
radical S-adenosyl methionine domain containing 2
chr11_+_37638873 0.76 ENSDART00000186384
ENSDART00000184291
ENSDART00000131782
ENSDART00000140502
SH2 domain containing 5
chr4_-_76370630 0.75 ENSDART00000168831
ENSDART00000174313
si:ch73-158p21.3
chr4_+_25558849 0.75 ENSDART00000113663
ENSDART00000100755
ENSDART00000111416
ENSDART00000127840
ENSDART00000168618
ENSDART00000111820
ENSDART00000113866
ENSDART00000110107
ENSDART00000111344
ENSDART00000108548
zgc:195175
chr14_+_36414856 0.71 ENSDART00000123343
ENSDART00000015761
nei-like DNA glycosylase 3
chr4_+_68776476 0.68 ENSDART00000169135
si:dkey-264f17.3
chr7_-_60351876 0.67 ENSDART00000098563
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr11_-_19775182 0.66 ENSDART00000037894
nicotinamide phosphoribosyltransferase b
chr5_-_41841675 0.66 ENSDART00000141683
si:dkey-65b12.6
chr23_+_5736226 0.65 ENSDART00000134527
ENSDART00000112220
finTRIM family, member 57
chr20_-_26936887 0.65 ENSDART00000160827
finTRIM family, member 79
chr19_+_14115838 0.64 ENSDART00000192057
keratinocyte differentiation factor 1b
chr18_-_38270430 0.64 ENSDART00000139519
cell cycle associated protein 1b
chr9_+_11293830 0.64 ENSDART00000144440
wingless-type MMTV integration site family, member 6b
chr15_-_21702317 0.63 ENSDART00000155824
si:dkey-40g16.6
chr3_+_938438 0.62 ENSDART00000165671
immunity-related GTPase family, f4
chr22_+_29990448 0.62 ENSDART00000165313
si:dkey-286j15.3
chr2_+_42294944 0.61 ENSDART00000140599
ENSDART00000178811
finTRIM family, member 6
chr3_-_37148594 0.60 ENSDART00000140855
MLX, MAX dimerization protein
chr5_-_26247973 0.59 ENSDART00000098527
endoplasmic reticulum aminopeptidase 1b
chr22_+_19230434 0.58 ENSDART00000132929
si:dkey-21e2.8
chr3_-_4760384 0.58 ENSDART00000108810

chr13_-_50200042 0.58 ENSDART00000074230
protein kinase containing Z-DNA binding domains
chr23_-_6865946 0.57 ENSDART00000056426
finTRIM family, member 58
chr3_-_34586403 0.57 ENSDART00000151515
septin 9a
chr18_-_38270077 0.57 ENSDART00000185546
cell cycle associated protein 1b
chr7_+_54260004 0.56 ENSDART00000171909
protein kinase C and casein kinase substrate in neurons 3
chr17_-_23631400 0.56 ENSDART00000079563
Fas cell surface death receptor
chr25_+_8955530 0.55 ENSDART00000156444
si:ch211-256a21.4
chr3_-_10739625 0.55 ENSDART00000156144
zgc:112965
chr7_-_7984015 0.55 ENSDART00000163203
si:cabz01030277.1
chr13_-_1151410 0.55 ENSDART00000007231
proteasome subunit beta 1
chr20_+_51199666 0.54 ENSDART00000169321
heat shock protein 90, alpha (cytosolic), class B member 1
chr9_-_23765480 0.52 ENSDART00000027212
si:ch211-219a4.6
chr18_-_38270596 0.52 ENSDART00000098889
cell cycle associated protein 1b
chr22_+_36902352 0.52 ENSDART00000036273
tripartite motif containing 35-20
chr19_+_4066449 0.52 ENSDART00000162461
bloodthirsty-related gene family, member 26
chr4_+_70782916 0.52 ENSDART00000187960
si:dkey-16p6.1
chr5_-_26247671 0.52 ENSDART00000145187
endoplasmic reticulum aminopeptidase 1b
chr11_+_1584747 0.50 ENSDART00000154583
si:dkey-40c23.2
chr20_-_20402500 0.48 ENSDART00000190747
ENSDART00000185065
protein kinase C, eta, b
chr3_-_11040575 0.48 ENSDART00000159802

chr24_+_24809877 0.48 ENSDART00000185117
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr3_-_7997887 0.47 ENSDART00000172256
si:ch211-175l6.2
chr1_-_58002973 0.47 ENSDART00000140390
si:ch211-114l13.9
chr18_-_6534357 0.46 ENSDART00000192886
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr1_-_8966046 0.46 ENSDART00000136198
suppressor of cytokine signaling 1b
chr23_-_35649000 0.46 ENSDART00000053310
transmembrane protein 18
chr9_+_23765587 0.44 ENSDART00000145120
si:ch211-219a4.3
chr3_-_7974028 0.43 ENSDART00000144459
tripartite motif containing 35-22
chr15_-_41749364 0.43 ENSDART00000155464
finTRIM family, member 73
chr5_-_38179220 0.42 ENSDART00000147701
si:ch211-284e13.11
chr14_-_48786708 0.42 ENSDART00000169730
si:ch211-199b20.3
chr5_+_38680061 0.42 ENSDART00000143259
si:dkey-58f10.11
chr13_-_50200348 0.41 ENSDART00000038391
protein kinase containing Z-DNA binding domains
chr3_+_8826905 0.41 ENSDART00000167474
ENSDART00000168088
si:dkeyp-30d6.2
chr10_-_45229877 0.41 ENSDART00000169281
poly (ADP-ribose) glycohydrolase, like
chr3_-_3398383 0.40 ENSDART00000047865
si:dkey-46g23.2
chr13_-_47810394 0.40 ENSDART00000105025
zmp:0000001138
chr5_+_38685089 0.40 ENSDART00000139743
si:dkey-58f10.10
chr4_+_53115165 0.39 ENSDART00000157470
si:dkey-8o9.2
chr5_+_38679623 0.39 ENSDART00000131879
ENSDART00000170010
si:dkey-58f10.11
si:dkey-58f10.10
chr12_-_13549538 0.38 ENSDART00000133895
GH3 domain containing
chr4_-_25215968 0.38 ENSDART00000066932
ENSDART00000066933
inter-alpha-trypsin inhibitor heavy chain 2
chr18_+_50525109 0.35 ENSDART00000098390
ubiquitin-like 7b (bone marrow stromal cell-derived)
chr18_-_6534516 0.34 ENSDART00000009217
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr16_-_43344859 0.34 ENSDART00000058680
proteasome subunit alpha 2
chr8_-_12867128 0.34 ENSDART00000142201
solute carrier family 2 (facilitated glucose transporter), member 6
chr2_-_47904043 0.32 ENSDART00000185328
ENSDART00000126740
finTRIM family, member 22
chr15_+_28355023 0.31 ENSDART00000122159
si:dkey-118k5.3
chr17_+_25833947 0.31 ENSDART00000044328
ENSDART00000154604
acyl-CoA synthetase short chain family member 1
chr19_-_7706926 0.31 ENSDART00000151270
si:dkey-204a24.11
chr4_+_70317135 0.31 ENSDART00000159286
si:dkey-29j8.1
chr3_-_7961226 0.30 ENSDART00000159801
tripartite motif containing 35-23
chr1_+_58360935 0.30 ENSDART00000140754
si:dkey-222h21.1
chr1_-_49530615 0.30 ENSDART00000113315
si:ch211-281g13.5
chr19_+_12350069 0.30 ENSDART00000052240
proteasome (prosome, macropain) assembly chaperone 2
chr9_-_14084044 0.30 ENSDART00000141571
fer-1-like family member 6
chr1_-_52201266 0.30 ENSDART00000143805
ENSDART00000023757
RAB3D, member RAS oncogene family, a
chr13_+_30912385 0.30 ENSDART00000182642
dorsal root ganglia homeobox
chr18_-_17724295 0.29 ENSDART00000121553
family with sequence similarity 192, member A
chr12_-_4598237 0.28 ENSDART00000152489
interferon regulatory factor 3
chr2_-_43745146 0.28 ENSDART00000056164
ENSDART00000098052
finTRIM family, member 96
chr9_+_42269059 0.27 ENSDART00000113435
si:dkey-10c21.1
chr4_+_70967639 0.27 ENSDART00000159230
si:dkeyp-80d11.12
chr7_+_26049818 0.27 ENSDART00000173611
si:dkey-6n21.12
chr4_-_50933168 0.27 ENSDART00000150296
si:ch211-208f21.3
chr24_-_8730913 0.27 ENSDART00000187228
ENSDART00000082349
ENSDART00000186660
transcription factor AP-2 alpha
chr16_-_50952266 0.26 ENSDART00000165408
si:dkeyp-97a10.3
chr4_+_279669 0.26 ENSDART00000184884

chr4_+_59841099 0.26 ENSDART00000144806
si:dkey-196n19.2
chr1_-_8141135 0.26 ENSDART00000152295
si:dkeyp-9d4.4
chr3_-_7940522 0.26 ENSDART00000159710
ENSDART00000167201
tripartite motif containing 35-25
chr5_+_38726854 0.25 ENSDART00000138484
ENSDART00000142867
si:dkey-58f10.7
chr4_-_60790123 0.25 ENSDART00000137702
si:dkey-254e13.6
chr22_+_5858467 0.25 ENSDART00000137295
si:dkey-222f2.7
chr2_+_42271830 0.25 ENSDART00000074027
ENSDART00000146444
finTRIM family, member 10
chr22_-_11520405 0.24 ENSDART00000063157
solute carrier family 26 (anion exchanger), member 11
chr2_-_707152 0.24 ENSDART00000082304
finTRIM family, member 93
chr6_+_42338309 0.24 ENSDART00000015277
glutathione peroxidase 1b
chr22_+_10158502 0.24 ENSDART00000005869
ribonuclease P/MRP 14 subunit
chr21_-_26715270 0.23 ENSDART00000053794
barrier to autointegration factor 1
chr4_-_76079075 0.23 ENSDART00000158469
si:ch211-232d10.3
chr3_+_1724941 0.23 ENSDART00000193402

chr1_+_50613868 0.23 ENSDART00000111114
si:ch73-190m4.1
chr22_-_6465060 0.23 ENSDART00000081687
zgc:172133
chr22_+_11520249 0.23 ENSDART00000063147
N-sulfoglucosamine sulfohydrolase (sulfamidase)
chr2_+_42236118 0.23 ENSDART00000114162
ENSDART00000141199
finTRIM family, member 2
chr25_+_245018 0.23 ENSDART00000155344
zgc:92481
chr4_+_33862438 0.23 ENSDART00000165044
si:dkey-28i19.3
chr5_-_37820878 0.22 ENSDART00000165513
Danio rerio uncharacterized LOC567472 (LOC567472), mRNA.
chr4_-_71177920 0.22 ENSDART00000158287
si:dkey-193i10.1
chr17_-_28811747 0.22 ENSDART00000001444
G2/M-phase specific E3 ubiquitin protein ligase
chr18_-_12858016 0.22 ENSDART00000130343
poly (ADP-ribose) polymerase family, member 12a
chr4_-_13567387 0.22 ENSDART00000132971
ENSDART00000102010
Mdm1 nuclear protein homolog (mouse)
chr3_+_36127287 0.22 ENSDART00000058605
ENSDART00000182500
serine carboxypeptidase 1
chr2_+_42318012 0.21 ENSDART00000138137
finTRIM family, member 8
chr4_+_70911498 0.21 ENSDART00000157674
si:dkey-16p6.1
chr1_-_52790724 0.21 ENSDART00000139577
ENSDART00000100937
protein associated with topoisomerase II homolog 1 (yeast)
chr17_-_23603263 0.21 ENSDART00000079559
interferon-induced protein with tetratricopeptide repeats 16
chr3_+_48473346 0.21 ENSDART00000166294
meteorin, glial cell differentiation regulator-like
chr6_-_19271210 0.20 ENSDART00000163628
ENSDART00000159124
zgc:174863
chr4_+_71366326 0.20 ENSDART00000170807
si:ch211-76m11.8
chr4_-_76027176 0.20 ENSDART00000165718
si:dkey-71l4.1
chr10_+_2899108 0.20 ENSDART00000147031
endoplasmic reticulum aminopeptidase 1a
chr5_-_26247215 0.19 ENSDART00000136806
endoplasmic reticulum aminopeptidase 1b
chr18_+_14684115 0.19 ENSDART00000108469
spermatogenesis associated 2-like
chr20_-_36408836 0.19 ENSDART00000076419
lamin B receptor
chr6_+_56076595 0.18 ENSDART00000169747
replication termination factor 2 domain containing 1
chr18_-_14901437 0.18 ENSDART00000145842
ENSDART00000008035
TraB domain containing
chr2_-_38287987 0.18 ENSDART00000185329
ENSDART00000061677
si:ch211-14a17.6
chr5_-_23715027 0.17 ENSDART00000139020
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr18_+_14693682 0.17 ENSDART00000132249
URI1, prefoldin-like chaperone
chr23_+_39970425 0.17 ENSDART00000165376
FYVE and coiled-coil domain containing 1a
chr2_+_49667767 0.16 ENSDART00000191013
ENSDART00000193757
ENSDART00000187134
ENSDART00000189100

chr10_+_40623414 0.16 ENSDART00000187616
zgc:172131
chr3_+_19336286 0.16 ENSDART00000111528
KRI1 homolog
chr22_+_9994833 0.16 ENSDART00000172696
ENSDART00000192101

chr4_+_8016457 0.16 ENSDART00000014036
optineurin
chr18_+_8812549 0.15 ENSDART00000017619
IMP (inosine 5'-monophosphate) dehydrogenase 1a
chr8_-_12867434 0.15 ENSDART00000081657
solute carrier family 2 (facilitated glucose transporter), member 6
chr21_-_11632403 0.15 ENSDART00000171708
ENSDART00000138619
ENSDART00000136308
ENSDART00000144770
calpastatin
chr6_+_56076848 0.15 ENSDART00000059438
ENSDART00000157040
replication termination factor 2 domain containing 1
chr11_-_30341431 0.15 ENSDART00000078378
CASP8 and FADD-like apoptosis regulator a
chr7_+_22792895 0.14 ENSDART00000184407
RNA binding motif protein 4.3

Network of associatons between targets according to the STRING database.

First level regulatory network of irf1a

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 1.0 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.3 1.3 GO:1903019 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.3 9.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.3 0.8 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.3 1.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.3 1.0 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.2 0.5 GO:0071635 transforming growth factor beta activation(GO:0036363) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635)
0.1 0.6 GO:0070227 lymphocyte apoptotic process(GO:0070227)
0.1 2.7 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.6 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.3 GO:0071514 genetic imprinting(GO:0071514)
0.1 1.4 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 3.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.5 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.6 GO:0014028 notochord formation(GO:0014028)
0.1 0.2 GO:0042546 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.1 1.0 GO:0046686 response to cadmium ion(GO:0046686)
0.1 0.3 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 0.3 GO:0006083 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.0 0.5 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 3.0 GO:0051607 defense response to virus(GO:0051607)
0.0 0.4 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.7 GO:0090279 regulation of calcium ion import(GO:0090279)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 1.8 GO:0010950 positive regulation of endopeptidase activity(GO:0010950) positive regulation of peptidase activity(GO:0010952)
0.0 0.2 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.7 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.1 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.2 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 0.3 GO:0051131 proteasome assembly(GO:0043248) chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.3 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.7 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.2 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.0 0.7 GO:0006289 nucleotide-excision repair(GO:0006289)
0.0 0.1 GO:0006031 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.7 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.1 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0035803 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.4 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0008537 proteasome activator complex(GO:0008537)
0.3 9.0 GO:0005839 proteasome core complex(GO:0005839)
0.2 1.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 1.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.9 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.6 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3 1.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.3 2.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.3 1.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.3 1.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2 1.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.4 GO:0004649 poly(ADP-ribose) glycohydrolase activity(GO:0004649)
0.1 3.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 3.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.7 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 1.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 3.0 GO:0032182 ubiquitin-like protein binding(GO:0032182)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 1.3 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.7 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 3.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.4 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.2 1.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 4.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 2.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 0.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)