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PRJNA207719: Tissue specific transcriptome profiling

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Results for hoxc8a

Z-value: 0.34

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Transcription factors associated with hoxc8a

Gene Symbol Gene ID Gene Info
hoxc8a
ENSDARG00000070346 homeobox C8a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hoxc8adr11_v1_chr23_+_36101185_36101185-0.098.9e-01Click!

Activity profile of hoxc8a motif

Sorted Z-values of hoxc8a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_23298928 0.33 ENSDART00000153652
zgc:165461
zgc:165461
chr4_-_815871 0.31 ENSDART00000067455
dpysl5b
dihydropyrimidinase-like 5b
chr15_-_15357178 0.31 ENSDART00000106120
ywhag2
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2
chr11_-_1509773 0.29 ENSDART00000050762
phactr3b
phosphatase and actin regulator 3b
chr13_-_35808904 0.28 ENSDART00000171667
map3k4
mitogen-activated protein kinase kinase kinase 4
chr18_+_7283283 0.27 ENSDART00000141493
ANO2 (1 of many)
si:ch73-86n2.1
chr20_+_40457599 0.27 ENSDART00000017553
serinc1
serine incorporator 1
chr13_+_13693722 0.27 ENSDART00000110509
si:ch211-194c3.5
si:ch211-194c3.5
chr5_+_27137473 0.26 ENSDART00000181833
unc5db
unc-5 netrin receptor Db
chr15_+_15856178 0.26 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr2_+_50608099 0.26 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr23_-_29505645 0.25 ENSDART00000146458
kif1b
kinesin family member 1B
chr8_+_31717175 0.25 ENSDART00000013434
oxct1a
3-oxoacid CoA transferase 1a
chr13_+_38521152 0.24 ENSDART00000145292
adgrb3
adhesion G protein-coupled receptor B3
chr5_+_30635309 0.24 ENSDART00000183769
abcg4a
ATP-binding cassette, sub-family G (WHITE), member 4a
chr8_+_31716872 0.23 ENSDART00000161121
oxct1a
3-oxoacid CoA transferase 1a
chr2_-_16380283 0.22 ENSDART00000149992
si:dkey-231j24.3
si:dkey-231j24.3
chr16_+_17389116 0.20 ENSDART00000103750
ENSDART00000173448
fam131bb
family with sequence similarity 131, member Bb
chr2_+_31833997 0.19 ENSDART00000066788
epdr1
ependymin related 1
chr14_-_30587814 0.19 ENSDART00000144912
ENSDART00000149714
tmem265
transmembrane protein 265
chr4_+_76926059 0.19 ENSDART00000136192
si:dkey-240n22.6
si:dkey-240n22.6
chr5_+_36768674 0.19 ENSDART00000146854
mark4a
MAP/microtubule affinity-regulating kinase 4a
chr6_-_30210378 0.18 ENSDART00000157359
ENSDART00000113924
lrrc7
leucine rich repeat containing 7
chr8_+_18624658 0.18 ENSDART00000089141
fsd1
fibronectin type III and SPRY domain containing 1
chr18_+_924949 0.18 ENSDART00000170888
ENSDART00000193163
pkma
pyruvate kinase M1/2a
chr20_-_14925281 0.18 ENSDART00000152641
dnm3a
dynamin 3a
chr6_+_40591149 0.17 ENSDART00000189060
ENSDART00000188298
frs3
fibroblast growth factor receptor substrate 3
chr3_+_46628885 0.17 ENSDART00000006602
pde4a
phosphodiesterase 4A, cAMP-specific
chr16_-_44945224 0.17 ENSDART00000156921
ncam3
neural cell adhesion molecule 3
chr14_-_47248784 0.17 ENSDART00000135479
fstl5
follistatin-like 5
chr14_-_27121854 0.16 ENSDART00000173119
pcdh11
protocadherin 11
chr2_-_33687214 0.16 ENSDART00000147439
atp6v0b
ATPase H+ transporting V0 subunit b
chr18_+_27738349 0.16 ENSDART00000187816
tspan18b
tetraspanin 18b
chr16_+_39159752 0.15 ENSDART00000122081
sybu
syntabulin (syntaxin-interacting)
chr17_+_23554932 0.15 ENSDART00000135814
pank1a
pantothenate kinase 1a
chr20_-_14924858 0.15 ENSDART00000047039
dnm3a
dynamin 3a
chr13_+_12299997 0.14 ENSDART00000108535
gabrb1
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr2_-_30668580 0.14 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr19_+_5480327 0.13 ENSDART00000148794
jupb
junction plakoglobin b
chr17_+_26611929 0.13 ENSDART00000166450
ENSDART00000087023
ttc7b
tetratricopeptide repeat domain 7B
chr23_+_40604951 0.13 ENSDART00000114959
cdh24a
cadherin 24, type 2a
chr24_-_29963858 0.13 ENSDART00000183442
CR352310.1

chr11_-_6188413 0.12 ENSDART00000109972
ccl44
chemokine (C-C motif) ligand 44
chr17_-_43556208 0.12 ENSDART00000188424
nt5c1ab
5'-nucleotidase, cytosolic IAb
chr7_-_67894046 0.12 ENSDART00000168964
si:ch73-315f9.2
si:ch73-315f9.2
chr18_+_17827149 0.12 ENSDART00000190237
ENSDART00000189345
ZNF423
si:ch211-216l23.1
chr20_+_38201644 0.11 ENSDART00000022694
ehd3
EH-domain containing 3
chr17_-_43556415 0.11 ENSDART00000190102
ENSDART00000193156
nt5c1ab
5'-nucleotidase, cytosolic IAb
chr20_-_9462433 0.11 ENSDART00000152674
ENSDART00000040557
zgc:101840
zgc:101840
chr24_-_7321928 0.11 ENSDART00000167570
ENSDART00000045150
actr3b
ARP3 actin related protein 3 homolog B
chr15_-_35252522 0.11 ENSDART00000144153
ENSDART00000059195
mff
mitochondrial fission factor
chr21_-_34032650 0.11 ENSDART00000138575
ENSDART00000047515
rnf145b
ring finger protein 145b
chr16_+_13818743 0.10 ENSDART00000090191
flcn
folliculin
chr21_-_5856050 0.10 ENSDART00000115367
CABZ01071020.1

chr25_-_13490744 0.10 ENSDART00000056721
ldhd
lactate dehydrogenase D
chr15_-_42736433 0.10 ENSDART00000154379
si:ch211-181d7.1
si:ch211-181d7.1
chr11_+_11267493 0.10 ENSDART00000148425
ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr20_-_34750045 0.10 ENSDART00000186130
znf395b
zinc finger protein 395b
chr5_-_68093169 0.10 ENSDART00000051849
slc25a11
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr13_-_39736938 0.09 ENSDART00000141645
zgc:171482
zgc:171482
chr4_+_14727018 0.09 ENSDART00000124189
cmasa
cytidine monophosphate N-acetylneuraminic acid synthetase a
chrM_+_9052 0.09 ENSDART00000093612
mt-atp6
ATP synthase 6, mitochondrial
chr11_-_40728380 0.09 ENSDART00000023745
ccdc114
coiled-coil domain containing 114
chr20_-_34750363 0.08 ENSDART00000152845
znf395b
zinc finger protein 395b
chr13_-_31812394 0.08 ENSDART00000124445
sertad4
SERTA domain containing 4
chr15_-_14552101 0.08 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr23_-_35790235 0.07 ENSDART00000142369
ENSDART00000141141
ENSDART00000011004
mfsd5
major facilitator superfamily domain containing 5
chr7_-_46777876 0.07 ENSDART00000193954
tshz3b
teashirt zinc finger homeobox 3b
chr15_+_29140126 0.07 ENSDART00000060034
zgc:113149
zgc:113149
chr11_+_33818179 0.07 ENSDART00000109418
spoplb
speckle-type POZ protein-like b
chr25_-_7705487 0.07 ENSDART00000128099
prdm11
PR domain containing 11
chr9_-_21918963 0.07 ENSDART00000090782
lmo7a
LIM domain 7a
chr19_-_205104 0.07 ENSDART00000011890
zbtb22a
zinc finger and BTB domain containing 22a
chr11_-_21528056 0.06 ENSDART00000181626
srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr8_-_7567815 0.06 ENSDART00000132536
hcfc1b
host cell factor C1b
chr4_+_14727212 0.06 ENSDART00000158094
cmasa
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr7_-_12464412 0.06 ENSDART00000178723
adamtsl3
ADAMTS-like 3
chr6_-_40713183 0.06 ENSDART00000157113
ENSDART00000154810
ENSDART00000153702
si:ch211-157b11.12
si:ch211-157b11.12
chr3_+_22442445 0.06 ENSDART00000190921
wnk4b
WNK lysine deficient protein kinase 4b
chr1_+_22691256 0.06 ENSDART00000017413
zmynd10
zinc finger, MYND-type containing 10
chr1_-_58036509 0.06 ENSDART00000081122
COLGALT1
si:ch211-114l13.7
chr21_+_22738939 0.06 ENSDART00000151342
ENSDART00000079145
arhgap42a
Rho GTPase activating protein 42a
chr13_+_36622100 0.06 ENSDART00000133198
si:ch211-67f24.7
si:ch211-67f24.7
chr5_+_63857055 0.05 ENSDART00000138950
rgs3b
regulator of G protein signaling 3b
chr15_-_23420079 0.05 ENSDART00000104525
ENSDART00000148840
kmt2a
lysine (K)-specific methyltransferase 2A
chr21_+_29077509 0.05 ENSDART00000128561
ecscr
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr2_+_16482338 0.05 ENSDART00000143912
fbxo36b
F-box protein 36b
chr13_+_31070181 0.05 ENSDART00000110560
ENSDART00000146088
si:ch211-223a10.1
si:ch211-223a10.1
chr7_-_48667056 0.05 ENSDART00000006378
cdkn1ca
cyclin-dependent kinase inhibitor 1Ca
chr1_+_39482588 0.05 ENSDART00000181790
tenm3
teneurin transmembrane protein 3
chr15_+_31899312 0.05 ENSDART00000155315
frya
furry homolog a (Drosophila)
chr21_+_30355767 0.05 ENSDART00000189948
CR749164.1

chr7_-_32895668 0.05 ENSDART00000141828
ano5b
anoctamin 5b
chr10_-_5847655 0.04 ENSDART00000192773
ankrd55
ankyrin repeat domain 55
chr6_+_49722970 0.04 ENSDART00000155934
ENSDART00000154738
stx16
syntaxin 16
chrM_+_9735 0.04 ENSDART00000093613
mt-co3
cytochrome c oxidase III, mitochondrial
chr16_-_13623928 0.04 ENSDART00000164344
si:dkeyp-69b9.6
si:dkeyp-69b9.6
chr6_+_19383267 0.04 ENSDART00000166549
mchr1a
melanin-concentrating hormone receptor 1a
chr4_+_49506359 0.04 ENSDART00000154478
si:dkey-5i16.5
si:dkey-5i16.5
chr11_+_30244356 0.04 ENSDART00000036050
ENSDART00000150080
rs1a
retinoschisin 1a
chr10_+_2899108 0.04 ENSDART00000147031
erap1a
endoplasmic reticulum aminopeptidase 1a
chr23_+_36130883 0.04 ENSDART00000103132
hoxc4a
homeobox C4a
chr21_+_8427059 0.04 ENSDART00000143151
dennd1a
DENN/MADD domain containing 1A
chr7_-_30174882 0.04 ENSDART00000110409
frmd5
FERM domain containing 5
chr11_-_44979281 0.04 ENSDART00000190972
ldb1b
LIM-domain binding 1b
chr22_+_29113796 0.04 ENSDART00000150264
pla2g6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr4_+_5333988 0.04 ENSDART00000129398
ENSDART00000163850
ENSDART00000067374
ENSDART00000150780
ENSDART00000150493
ENSDART00000150306
apex1
APEX nuclease (multifunctional DNA repair enzyme) 1
chr6_+_49723289 0.03 ENSDART00000190452
stx16
syntaxin 16
chr5_+_69981453 0.03 ENSDART00000143860
si:ch211-154e10.1
si:ch211-154e10.1
chr16_-_13623659 0.03 ENSDART00000168978
si:dkeyp-69b9.6
si:dkeyp-69b9.6
chr24_+_26997798 0.03 ENSDART00000089506
larp4b
La ribonucleoprotein domain family, member 4B
chr8_+_16676894 0.03 ENSDART00000076586
si:ch211-198n5.11
si:ch211-198n5.11
chr2_+_20793982 0.03 ENSDART00000014785
prg4a
proteoglycan 4a
chr19_+_33850705 0.03 ENSDART00000160356
pex1
peroxisomal biogenesis factor 1
chr10_-_26744131 0.03 ENSDART00000020096
ENSDART00000162710
ENSDART00000179853
fgf13b
fibroblast growth factor 13b
chr5_+_29671681 0.03 ENSDART00000043096
ak8
adenylate kinase 8
chr13_+_35339182 0.03 ENSDART00000019323
jag1b
jagged 1b
chr20_-_27225876 0.03 ENSDART00000149204
ENSDART00000149732
si:dkey-85n7.7
si:dkey-85n7.7
chr10_+_11355841 0.02 ENSDART00000193067
ENSDART00000064215
cops4
COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)
chr1_+_524388 0.02 ENSDART00000020327
mrpl16
mitochondrial ribosomal protein L16
chr17_+_50248152 0.02 ENSDART00000153998
zc2hc1c
zinc finger, C2HC-type containing 1C
chr9_+_32178374 0.02 ENSDART00000078576
coq10b
coenzyme Q10B
chr19_-_33850201 0.02 ENSDART00000168583
otud6b
OTU domain containing 6B
chr21_+_35327589 0.02 ENSDART00000145191
ENSDART00000132743
rars
arginyl-tRNA synthetase
chr15_-_38154616 0.02 ENSDART00000099392
irgq2
immunity-related GTPase family, q2
chr13_-_45811137 0.02 ENSDART00000190512
fndc5a
fibronectin type III domain containing 5a
chr10_-_35108683 0.01 ENSDART00000049633
zgc:110006
zgc:110006
chr2_-_28671139 0.01 ENSDART00000165272
ENSDART00000164657
dhcr7
7-dehydrocholesterol reductase
chr21_+_35328025 0.01 ENSDART00000136211
rars
arginyl-tRNA synthetase
chr24_+_36204028 0.01 ENSDART00000063832
ENSDART00000155260
rbbp8
retinoblastoma binding protein 8
chr3_+_7808459 0.01 ENSDART00000162374
hook2
hook microtubule-tethering protein 2
chr24_+_22485710 0.01 ENSDART00000146058
si:dkey-40h20.1
si:dkey-40h20.1
chr11_+_45110865 0.01 ENSDART00000158188
mgea5l
meningioma expressed antigen 5 (hyaluronidase) like
chr3_+_30500968 0.00 ENSDART00000103447
si:dkey-13n23.3
si:dkey-13n23.3
chr3_+_29179329 0.00 ENSDART00000085216
ENSDART00000190136
cacna1i
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr14_-_16082806 0.00 ENSDART00000165656
mxd3
MAX dimerization protein 3
chr8_-_39822917 0.00 ENSDART00000067843
zgc:162025
zgc:162025
chr3_-_34084387 0.00 ENSDART00000155365
ighv4-3
immunoglobulin heavy variable 4-3
chr16_+_4497302 0.00 ENSDART00000081826
ENSDART00000148096
ttc29
tetratricopeptide repeat domain 29

Network of associatons between targets according to the STRING database.

First level regulatory network of hoxc8a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.2 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:0060074 synapse maturation(GO:0060074)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.1 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.3 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.0 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0033344 cholesterol efflux(GO:0033344)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.0 GO:0030273 melanin-concentrating hormone receptor activity(GO:0030273)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling