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PRJNA207719: Tissue specific transcriptome profiling
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Results for hnf4g
Z-value: 1.44
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Transcription factors associated with hnf4g
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| hnf4g | dr11_v1_chr24_-_23671709_23671709 | 0.91 | 3.4e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr22_-_24818066 Show fit | 2.46 |
ENSDART00000143443
|
vitellogenin 6 |
|
| chr21_-_27443995 Show fit | 1.74 |
ENSDART00000003508
|
complement component bfb |
|
| chr17_-_2590222 Show fit | 1.66 |
ENSDART00000185711
|
|
|
| chr17_-_2578026 Show fit | 1.63 |
ENSDART00000065821
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
|
| chr17_-_2584423 Show fit | 1.62 |
ENSDART00000013506
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
|
| chr17_-_2573021 Show fit | 1.58 |
ENSDART00000074181
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
|
| chr22_-_24738188 Show fit | 1.52 |
ENSDART00000050238
|
vitellogenin 1 |
|
| chr22_+_16022211 Show fit | 1.43 |
ENSDART00000062618
|
serpin peptidase inhibitor, clade C (antithrombin), member 1 |
|
| chr15_-_16012963 Show fit | 1.40 |
ENSDART00000144138
|
HNF1 homeobox Ba |
|
| chr17_-_2595736 Show fit | 1.35 |
ENSDART00000128797
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of hnf4g
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 6.2 | GO:0035803 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344) |
| 0.1 | 4.0 | GO:0032355 | response to estradiol(GO:0032355) |
| 0.0 | 1.7 | GO:0006956 | complement activation(GO:0006956) |
| 0.5 | 1.4 | GO:2000257 | regulation of protein activation cascade(GO:2000257) |
| 0.2 | 1.4 | GO:0021572 | rhombomere 5 development(GO:0021571) rhombomere 6 development(GO:0021572) |
| 0.1 | 1.1 | GO:0071715 | icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571) |
| 0.2 | 1.0 | GO:0019483 | beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483) |
| 0.0 | 0.9 | GO:0042738 | drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) |
| 0.3 | 0.8 | GO:0034375 | high-density lipoprotein particle remodeling(GO:0034375) |
| 0.0 | 0.7 | GO:0030073 | insulin secretion(GO:0030073) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.5 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.1 | 0.8 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.1 | 0.5 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.0 | 0.2 | GO:0030428 | cell septum(GO:0030428) |
| 0.0 | 0.1 | GO:0033557 | Slx1-Slx4 complex(GO:0033557) |
| 0.0 | 0.1 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 6.2 | GO:0035804 | structural constituent of egg coat(GO:0035804) |
| 0.6 | 4.0 | GO:0045735 | nutrient reservoir activity(GO:0045735) |
| 0.0 | 1.4 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 0.0 | 1.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 1.2 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.1 | 0.9 | GO:0016803 | ether hydrolase activity(GO:0016803) |
| 0.0 | 0.9 | GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) |
| 0.0 | 0.8 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.0 | 0.7 | GO:0015245 | fatty acid transporter activity(GO:0015245) |
| 0.0 | 0.7 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.4 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 0.7 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 0.4 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.0 | 0.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.4 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.4 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.1 | 1.0 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.1 | 0.8 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 0.7 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.0 | 0.7 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 0.4 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.0 | 0.4 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 0.0 | 0.2 | REACTOME ACYL CHAIN REMODELLING OF PI | Genes involved in Acyl chain remodelling of PI |
| 0.0 | 0.2 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |