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PRJNA207719: Tissue specific transcriptome profiling

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Results for hnf4g

Z-value: 1.44

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Transcription factors associated with hnf4g

Gene Symbol Gene ID Gene Info
hnf4g
ENSDARG00000071565 hepatocyte nuclear factor 4, gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
hnf4gdr11_v1_chr24_-_23671709_236717090.913.4e-02Click!

Activity profile of hnf4g motif

Sorted Z-values of hnf4g motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_24818066 2.46 ENSDART00000143443
vtg6
vitellogenin 6
chr21_-_27443995 1.74 ENSDART00000003508
bfb
complement component bfb
chr17_-_2590222 1.66 ENSDART00000185711
CR759892.1

chr17_-_2578026 1.63 ENSDART00000065821
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr17_-_2584423 1.62 ENSDART00000013506
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr17_-_2573021 1.58 ENSDART00000074181
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr22_-_24738188 1.52 ENSDART00000050238
vtg1
vitellogenin 1
chr22_+_16022211 1.43 ENSDART00000062618
serpinc1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr15_-_16012963 1.40 ENSDART00000144138
hnf1ba
HNF1 homeobox Ba
chr17_-_2595736 1.35 ENSDART00000128797
zp3.2
zona pellucida glycoprotein 3, tandem duplicate 2
chr10_+_19569052 1.32 ENSDART00000058425
CABZ01059627.1

chr6_-_607063 1.22 ENSDART00000189900
lgals2b
lectin, galactoside-binding, soluble, 2b
chr4_-_77114795 1.07 ENSDART00000144849
CU467646.2

chr8_+_30699429 1.03 ENSDART00000005345
upb1
ureidopropionase, beta
chr3_+_16762483 0.90 ENSDART00000132732
tmem86b
transmembrane protein 86B
chr17_+_20173882 0.89 ENSDART00000155379
si:ch211-248a14.8
si:ch211-248a14.8
chr17_+_20174044 0.80 ENSDART00000156028
si:ch211-248a14.8
si:ch211-248a14.8
chr18_+_17611627 0.80 ENSDART00000046891
cetp
cholesteryl ester transfer protein, plasma
chr8_-_49207319 0.77 ENSDART00000022870
fam110a
family with sequence similarity 110, member A
chr9_+_8380728 0.76 ENSDART00000133501
si:ch1073-75o15.4
si:ch1073-75o15.4
chr19_-_25519310 0.74 ENSDART00000089882
C1GALT1 (1 of many)
si:dkey-202e17.1
chr20_-_25522911 0.74 ENSDART00000063058
cyp2n13
cytochrome P450, family 2, subfamily N, polypeptide 13
chr6_+_27624023 0.72 ENSDART00000147789
slco2a1
solute carrier organic anion transporter family, member 2A1
chr8_+_39802506 0.70 ENSDART00000018862
hnf1a
HNF1 homeobox a
chr13_-_35908275 0.54 ENSDART00000013961
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr9_-_44953664 0.53 ENSDART00000188558
ENSDART00000185210
vil1
villin 1
chr5_-_62317496 0.52 ENSDART00000180089
zgc:85789
zgc:85789
chr25_+_29472361 0.51 ENSDART00000154857
il17rel
interleukin 17 receptor E-like
chr13_-_40726865 0.47 ENSDART00000099847
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr17_-_30702411 0.46 ENSDART00000114358
zgc:194392
zgc:194392
chr5_-_69180587 0.46 ENSDART00000156681
ENSDART00000160753
zgc:171967
zgc:171967
chr5_-_69180227 0.44 ENSDART00000154816
zgc:171967
zgc:171967
chr8_+_24745041 0.43 ENSDART00000148872
slc16a4
solute carrier family 16, member 4
chr7_-_26518086 0.43 ENSDART00000058913
eif4a1a
eukaryotic translation initiation factor 4A1A
chr12_-_10567188 0.43 ENSDART00000144283
myof
myoferlin
chr4_-_17725008 0.41 ENSDART00000016658
chpt1
choline phosphotransferase 1
chr2_-_10877765 0.41 ENSDART00000100607
cdc7
cell division cycle 7 homolog (S. cerevisiae)
chr21_-_31290582 0.39 ENSDART00000065362
ca4c
carbonic anhydrase IV c
chr7_-_24520866 0.39 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr23_+_19790962 0.38 ENSDART00000142228
flna
filamin A, alpha (actin binding protein 280)
chr20_+_29436601 0.38 ENSDART00000136804
fmn1
formin 1
chr21_-_43428040 0.36 ENSDART00000148325
stk26
serine/threonine protein kinase 26
chr21_-_5879897 0.35 ENSDART00000184034
rpl35
ribosomal protein L35
chr20_+_23238833 0.33 ENSDART00000074167
ociad2
OCIA domain containing 2
chr13_-_35907768 0.33 ENSDART00000147522
mycla
MYCL proto-oncogene, bHLH transcription factor a
chr22_+_19407531 0.32 ENSDART00000141060
si:dkey-78l4.2
si:dkey-78l4.2
chr4_-_72468168 0.32 ENSDART00000182995
ENSDART00000174067
CR788316.1

chr16_+_9495583 0.31 ENSDART00000150750
ENSDART00000150457
pimr208
Pim proto-oncogene, serine/threonine kinase, related 208
chr16_+_26846495 0.31 ENSDART00000078124
trim35-29
tripartite motif containing 35-29
chr4_+_21741228 0.30 ENSDART00000112035
ENSDART00000127664
myf5
myogenic factor 5
chr9_+_1138802 0.30 ENSDART00000191130
ENSDART00000187308
slc15a1a
solute carrier family 15 (oligopeptide transporter), member 1a
chr10_-_39055620 0.30 ENSDART00000187437
igsf5a
immunoglobulin superfamily, member 5a
chr25_+_8316953 0.29 ENSDART00000154598
muc2.2
mucin 2.2, oligomeric mucus/gel-forming
chr15_+_34069746 0.29 ENSDART00000163513
arl4aa
ADP-ribosylation factor-like 4aa
chr23_+_2740741 0.29 ENSDART00000134938
zgc:114123
zgc:114123
chr15_-_31366742 0.28 ENSDART00000125585
or111-3
odorant receptor, family D, subfamily 111, member 3
chr1_-_9644630 0.27 ENSDART00000123725
ENSDART00000161164
ugt5b3
UDP glucuronosyltransferase 5 family, polypeptide B3
chr16_+_11660839 0.27 ENSDART00000193911
ENSDART00000143683
si:dkey-250k15.10
si:dkey-250k15.10
chr1_-_37383741 0.27 ENSDART00000193155
ENSDART00000191887
ENSDART00000189077
scpp1
secretory calcium-binding phosphoprotein 1
chr24_+_1294176 0.26 ENSDART00000106637
si:ch73-134f24.1
si:ch73-134f24.1
chr4_+_57099307 0.26 ENSDART00000131654
si:ch211-238e22.2
si:ch211-238e22.2
chr6_+_59029485 0.26 ENSDART00000050140
CABZ01088367.1

chr19_+_18983900 0.25 ENSDART00000161005
cmtm8a
CKLF-like MARVEL transmembrane domain containing 8a
chr18_+_33725576 0.24 ENSDART00000146816
si:dkey-145c18.5
si:dkey-145c18.5
chr7_-_29341233 0.24 ENSDART00000140938
ENSDART00000147251
trpm1a
transient receptor potential cation channel, subfamily M, member 1a
chr9_+_29994439 0.24 ENSDART00000012447
tmem30c
transmembrane protein 30C
chr13_+_18520738 0.24 ENSDART00000113952
tlr4al
toll-like receptor 4a, like
chr6_-_46474483 0.23 ENSDART00000155761
rdh20
retinol dehydrogenase 20
chr12_-_44122412 0.23 ENSDART00000169094
si:ch73-329n5.3
si:ch73-329n5.3
chr19_+_10536093 0.23 ENSDART00000138706
si:dkey-211g8.1
si:dkey-211g8.1
chr6_+_18298444 0.22 ENSDART00000166018
card14
caspase recruitment domain family, member 14
chr24_-_36175365 0.22 ENSDART00000065338
pak1ip1
PAK1 interacting protein 1
chr7_-_39738460 0.21 ENSDART00000052201
ccdc96
coiled-coil domain containing 96
chr21_-_43474012 0.21 ENSDART00000065104
tmem185
transmembrane protein 185
chr4_-_170120 0.20 ENSDART00000171333
eps8
epidermal growth factor receptor pathway substrate 8
chr23_-_43595956 0.20 ENSDART00000162186
itchb
itchy E3 ubiquitin protein ligase b
chr9_+_1138323 0.20 ENSDART00000190352
ENSDART00000190387
slc15a1a
solute carrier family 15 (oligopeptide transporter), member 1a
chr1_-_12064715 0.19 ENSDART00000143628
ENSDART00000103406
pla2g12a
phospholipase A2, group XIIA
chr4_+_38981587 0.17 ENSDART00000142713
si:dkey-66k12.3
si:dkey-66k12.3
chr1_-_37383539 0.17 ENSDART00000127579
scpp1
secretory calcium-binding phosphoprotein 1
chr4_+_53145525 0.17 ENSDART00000166960
si:dkey-8o9.2
si:dkey-8o9.2
chr2_-_10450784 0.17 ENSDART00000081196
scinlb
scinderin like b
chr7_+_29115890 0.17 ENSDART00000052345
tradd
tnfrsf1a-associated via death domain
chr20_-_49657134 0.17 ENSDART00000151248
col12a1b
collagen, type XII, alpha 1b
chr1_-_59169815 0.16 ENSDART00000100163
wu:fk65c09
wu:fk65c09
chr7_-_52417060 0.16 ENSDART00000148579
myzap
myocardial zonula adherens protein
chr13_-_303137 0.16 ENSDART00000099131
chs1
chitin synthase 1
chr2_-_37896965 0.16 ENSDART00000129852
hbl1
hexose-binding lectin 1
chr20_-_46694573 0.15 ENSDART00000182557
AL929435.2

chr3_+_12764894 0.15 ENSDART00000166071
cyp2k16
cytochrome P450, family 2, subfamily K, polypeptide16
chr1_-_57129179 0.15 ENSDART00000157226
ENSDART00000152469
si:ch73-94k4.2
si:ch73-94k4.2
chr8_-_20838342 0.15 ENSDART00000141345
si:ch211-133l5.7
si:ch211-133l5.7
chr23_+_17437554 0.15 ENSDART00000184282
BX649300.3

chr7_-_59514547 0.14 ENSDART00000168457
slx1b
SLX1 homolog B, structure-specific endonuclease subunit
chr7_+_17229282 0.14 ENSDART00000097982
slc6a5
solute carrier family 6 (neurotransmitter transporter), member 5
chr1_-_9485939 0.13 ENSDART00000157814
micall2b
mical-like 2b
chr11_+_22134540 0.13 ENSDART00000190502
MDFI
si:dkey-91m3.1
chr21_-_11856143 0.13 ENSDART00000151204
ube2r2
ubiquitin-conjugating enzyme E2R 2
chr13_-_50309969 0.13 ENSDART00000191597
CU928131.1

chr7_-_72352043 0.12 ENSDART00000163536
muc5f
mucin 5f
chr14_-_16810401 0.12 ENSDART00000158396
ENSDART00000170758
tcirg1b
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3b
chr16_+_11623956 0.11 ENSDART00000137788
cxcr3.1
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr14_+_9009600 0.11 ENSDART00000133904
si:ch211-274f20.2
si:ch211-274f20.2
chr25_+_5288665 0.11 ENSDART00000169540
CABZ01039861.1

chr16_+_54875530 0.10 ENSDART00000149795
nr0b2a
nuclear receptor subfamily 0, group B, member 2a
chr7_+_31398775 0.10 ENSDART00000124820
si:ch211-150j10.4
si:ch211-150j10.4
chr7_+_39738505 0.10 ENSDART00000004365
tada2b
transcriptional adaptor 2B
chr8_+_23390844 0.09 ENSDART00000184556
si:dkey-16n15.6
si:dkey-16n15.6
chr20_-_46128590 0.09 ENSDART00000123744
taar1b
trace amine associated receptor 1b
chr22_-_24992532 0.09 ENSDART00000102751
si:dkey-179j5.5
si:dkey-179j5.5
chr1_-_52292235 0.09 ENSDART00000132638
si:dkey-121b10.7
si:dkey-121b10.7
chr6_-_10788065 0.09 ENSDART00000190968
wipf1b
WAS/WASL interacting protein family, member 1b
chr17_-_6076266 0.08 ENSDART00000171084
ephx2
epoxide hydrolase 2, cytoplasmic
chr10_-_21953643 0.08 ENSDART00000188921
ENSDART00000193569
FO744833.2

chr2_-_42958619 0.08 ENSDART00000144317
oc90
otoconin 90
chr13_+_26703922 0.08 ENSDART00000020946
fancl
Fanconi anemia, complementation group L
chr22_-_20376488 0.07 ENSDART00000140187
zbtb7a
zinc finger and BTB domain containing 7a
chr6_-_9251122 0.07 ENSDART00000167835
BX119909.1

chr24_+_20960216 0.07 ENSDART00000133008
si:ch211-161h7.8
si:ch211-161h7.8
chr23_-_2448234 0.07 ENSDART00000082097
LO018513.1

chr2_-_42958113 0.07 ENSDART00000139945
oc90
otoconin 90
chr9_-_1986014 0.06 ENSDART00000142842
hoxd12a
homeobox D12a
chr7_+_5920665 0.06 ENSDART00000173208
si:dkey-23a13.11
si:dkey-23a13.11
chr24_+_7828097 0.06 ENSDART00000134975
zgc:101569
zgc:101569
chr13_-_37254777 0.06 ENSDART00000139734
syne2b
spectrin repeat containing, nuclear envelope 2b
chr14_-_16379843 0.06 ENSDART00000090711
ltc4s
leukotriene C4 synthase
chr7_+_24520518 0.06 ENSDART00000173604
btr09
bloodthirsty-related gene family, member 9
chr2_+_11670270 0.05 ENSDART00000100524
ftr01
finTRIM family, member 1
chr17_+_2734331 0.05 ENSDART00000067542
kcnk10b
potassium channel, subfamily K, member 10b
chr24_-_32150276 0.04 ENSDART00000166212
cubn
cubilin (intrinsic factor-cobalamin receptor)
chr3_-_8765165 0.04 ENSDART00000191131
CABZ01058333.1

chr6_-_56103718 0.04 ENSDART00000191002
gcnt7
glucosaminyl (N-acetyl) transferase family member 7
chr12_+_22607761 0.04 ENSDART00000153112
si:dkey-219e21.2
si:dkey-219e21.2
chr15_-_14884332 0.03 ENSDART00000165237
si:ch211-24o8.4
si:ch211-24o8.4
chr22_+_2844865 0.03 ENSDART00000139123
si:dkey-20i20.4
si:dkey-20i20.4
chr5_+_37069605 0.03 ENSDART00000161977
si:dkeyp-110c7.4
si:dkeyp-110c7.4
chr11_-_5563498 0.02 ENSDART00000160835
pex11g
peroxisomal biogenesis factor 11 gamma
chr25_+_22216723 0.02 ENSDART00000051291
hexa
hexosaminidase A (alpha polypeptide)
chr15_-_2632891 0.02 ENSDART00000081840
cldnj
claudin j
chr8_+_47188154 0.00 ENSDART00000137319
si:dkeyp-100a1.6
si:dkeyp-100a1.6

Network of associatons between targets according to the STRING database.

First level regulatory network of hnf4g

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.4 6.2 GO:0035803 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.3 0.8 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.2 1.4 GO:0021572 rhombomere 5 development(GO:0021571) rhombomere 6 development(GO:0021572)
0.2 1.0 GO:0019483 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.2 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.5 GO:2000392 lamellipodium morphogenesis(GO:0072673) regulation of lamellipodium morphogenesis(GO:2000392)
0.1 1.1 GO:0071715 icosanoid transport(GO:0071715) fatty acid derivative transport(GO:1901571)
0.1 4.0 GO:0032355 response to estradiol(GO:0032355)
0.1 0.5 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.3 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.0 0.2 GO:1901073 chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.7 GO:0030073 insulin secretion(GO:0030073)
0.0 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 1.7 GO:0006956 complement activation(GO:0006956)
0.0 0.9 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:0043092 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.0 0.4 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.1 GO:0006691 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.4 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 0.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0032433 filopodium tip(GO:0032433)
0.1 0.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 0.2 GO:0030428 cell septum(GO:0030428)
0.0 6.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.0 GO:0045735 nutrient reservoir activity(GO:0045735)
0.6 6.2 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 0.5 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 1.2 GO:0016936 galactoside binding(GO:0016936)
0.1 0.9 GO:0016803 ether hydrolase activity(GO:0016803)
0.1 0.4 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 0.5 GO:0042936 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.1 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.7 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.8 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.4 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 0.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex