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PRJNA207719: Tissue specific transcriptome profiling

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Results for hey2_hey1+heyl

Z-value: 1.34

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Transcription factors associated with hey2_hey1+heyl

Gene Symbol Gene ID Gene Info
ENSDARG00000013441 hes-related family bHLH transcription factor with YRPW motif 2
ENSDARG00000055798 hes related family bHLH transcription factor with YRPW motif like
ENSDARG00000070538 hes-related family bHLH transcription factor with YRPW motif 1
ENSDARG00000112770 hes related family bHLH transcription factor with YRPW motif like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
heyldr11_v1_chr19_+_32553874_32553874-0.316.1e-01Click!
hey1dr11_v1_chr19_-_31802296_318022960.237.1e-01Click!
hey2dr11_v1_chr20_-_39596338_39596338-0.167.9e-01Click!

Activity profile of hey2_hey1+heyl motif

Sorted Z-values of hey2_hey1+heyl motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_6780340 1.15 ENSDART00000139493
ENSDART00000140478
olfactomedin 1b
chr6_-_60147517 1.11 ENSDART00000083453
solute carrier family 32 (GABA vesicular transporter), member 1
chr20_+_34915945 1.01 ENSDART00000153064
synaptosomal-associated protein, 25a
chr14_+_35748385 0.87 ENSDART00000064617
ENSDART00000074671
ENSDART00000172803
glutamate receptor, ionotropic, AMPA 2b
chr14_+_35748206 0.86 ENSDART00000177391
glutamate receptor, ionotropic, AMPA 2b
chr10_-_7913591 0.78 ENSDART00000139661
solute carrier family 35, member E4
chr20_+_23440632 0.73 ENSDART00000180685
ENSDART00000042820
si:dkey-90m5.4
chr25_+_3328487 0.71 ENSDART00000181143
lactate dehydrogenase Bb
chr3_+_23488652 0.70 ENSDART00000126282
nuclear receptor subfamily 1, group d, member 1
chr8_+_21146262 0.68 ENSDART00000045684
porcupine O-acyltransferase
chr7_-_40993456 0.67 ENSDART00000031700
engrailed homeobox 2a
chr1_-_39943596 0.67 ENSDART00000149730
storkhead box 2a
chr10_+_10677697 0.64 ENSDART00000188705
family with sequence similarity 163, member B
chr11_-_3552067 0.62 ENSDART00000163656
si:dkey-33m11.6
chr14_-_30387894 0.59 ENSDART00000176136
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr23_-_24856025 0.59 ENSDART00000142171
synaptotagmin VIa
chr2_+_21090317 0.57 ENSDART00000109568
ENSDART00000139633
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b
chr19_-_24555935 0.57 ENSDART00000132660
ENSDART00000162801
polymerase (RNA) III (DNA directed) polypeptide G like a
chr1_+_7956030 0.57 ENSDART00000159655

chr8_-_42238543 0.55 ENSDART00000062697
GDNF family receptor alpha 2a
chr15_+_16897554 0.55 ENSDART00000154679
yippee-like 2b
chr7_+_38717624 0.55 ENSDART00000132522
synaptotagmin XIII
chr2_+_18988407 0.55 ENSDART00000170216
glutamate-ammonia ligase (glutamine synthase) a
chr19_-_8940068 0.54 ENSDART00000043507
circadian associated repressor of transcription a
chr4_-_16824231 0.54 ENSDART00000014007
glycogen synthase 2
chr7_-_30082931 0.54 ENSDART00000075600
tetraspanin 3b
chr21_+_31150773 0.53 ENSDART00000126205
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr10_+_17026870 0.53 ENSDART00000184529
ENSDART00000157480

chr18_-_19103929 0.52 ENSDART00000188370
ENSDART00000177621
DENN/MADD domain containing 4A
chr17_+_24318753 0.52 ENSDART00000064083
orthodenticle homeobox 1
chr7_+_38750871 0.52 ENSDART00000114238
ENSDART00000052325
ENSDART00000137001
coagulation factor II (thrombin)
chr3_+_1015867 0.51 ENSDART00000109912
si:ch1073-464p5.5
chr21_+_31150438 0.50 ENSDART00000065366
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr21_-_42100471 0.48 ENSDART00000166148
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr4_-_16824556 0.48 ENSDART00000165289
ENSDART00000185839
glycogen synthase 2
chr25_+_37268900 0.47 ENSDART00000156737
si:dkey-234i14.6
chr8_+_17184602 0.47 ENSDART00000050228
ENSDART00000140531
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr24_+_39135419 0.47 ENSDART00000180941
TBC1 domain family, member 24
chr8_-_23081511 0.47 ENSDART00000142015
ENSDART00000135764
ENSDART00000147021
si:dkey-70p6.1
chr5_+_26075230 0.47 ENSDART00000098473
Kruppel-like factor 9
chr18_-_21218851 0.46 ENSDART00000060160
calbindin 2a
chr17_-_17948587 0.46 ENSDART00000090447
HHIP-like 1
chr18_+_19990412 0.45 ENSDART00000155054
ENSDART00000090310
protein inhibitor of activated STAT, 1b
chr18_-_40684756 0.45 ENSDART00000113799
ENSDART00000139042
si:ch211-132b12.7
chr13_-_4992395 0.45 ENSDART00000102651
nucleolar and coiled-body phosphoprotein 1
chr2_+_20331445 0.44 ENSDART00000186880
phospholipid phosphatase related 4a
chr2_+_29976419 0.44 ENSDART00000056748
engrailed homeobox 2b
chr24_-_38644937 0.44 ENSDART00000170194
solute carrier family 6, member 16b
chr5_+_43470544 0.44 ENSDART00000111587
Rho-related BTB domain containing 2a
chr11_-_3959889 0.43 ENSDART00000159683
polybromo 1
chr19_-_24555623 0.43 ENSDART00000176022
polymerase (RNA) III (DNA directed) polypeptide G like a
chr1_+_17695426 0.43 ENSDART00000103236
ankyrin repeat domain 37
chr22_+_438714 0.43 ENSDART00000136491
cadherin, EGF LAG seven-pass G-type receptor 2
chr8_-_31606514 0.42 ENSDART00000018886
growth hormone receptor a
chr18_+_6479963 0.40 ENSDART00000092752
ENSDART00000136333
WAS protein family homolog 1
chr2_-_9489611 0.40 ENSDART00000146715
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr23_-_21463788 0.39 ENSDART00000079265
hairy-related 4, tandem duplicate 4
chr13_+_31402067 0.39 ENSDART00000019202
tudor domain containing 9
chr3_-_62380146 0.39 ENSDART00000155853
G protein-coupled receptor, class C, group 5, member Ba
chr24_-_12938922 0.39 ENSDART00000024084
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr2_-_32513538 0.39 ENSDART00000056640
ATP-binding cassette, sub-family F (GCN20), member 2a
chr17_+_25414033 0.38 ENSDART00000001691
L-threonine dehydrogenase 2
chr13_+_39277178 0.38 ENSDART00000113259
si:dkey-85a20.4
chr22_-_20105969 0.37 ENSDART00000088687
relaxin/insulin-like family peptide receptor 3.2b
chr2_+_22659787 0.36 ENSDART00000043956
zgc:161973
chr12_+_24342303 0.36 ENSDART00000111239
neurexin 1a
chr17_-_7440397 0.36 ENSDART00000162597
glutamate receptor, metabotropic 1b
chr10_-_41450367 0.35 ENSDART00000122682
ENSDART00000189549
calcium binding protein 1b
chr4_+_5180650 0.35 ENSDART00000067390
fibroblast growth factor 6b
chr15_-_20731297 0.35 ENSDART00000114464
tyrosylprotein sulfotransferase 1
chr12_-_15620090 0.34 ENSDART00000038032
acyl-CoA binding domain containing 4
chr11_+_45299447 0.34 ENSDART00000172999
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
chr8_-_26961779 0.34 ENSDART00000099214
solute carrier family 16 (monocarboxylate transporter), member 1b
chr16_-_31622777 0.33 ENSDART00000137311
ENSDART00000002930
PHD finger protein 20 like 1
chr5_+_4366431 0.33 ENSDART00000168560
ENSDART00000149185
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr19_+_6938289 0.32 ENSDART00000139122
ENSDART00000178832
flotillin 1b
chr24_-_22702017 0.32 ENSDART00000179403
catenin (cadherin-associated protein), delta 2a
chr2_-_44720551 0.31 ENSDART00000146380
MAP6 domain containing 1
chr13_+_41917606 0.31 ENSDART00000114741
polymerase (RNA) I polypeptide B
chr5_+_1965296 0.31 ENSDART00000156224
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr7_+_31319876 0.31 ENSDART00000187611
family with sequence similarity 189, member A1
chr19_-_3303995 0.31 ENSDART00000105150
si:ch211-133n4.9
chr20_+_50115335 0.30 ENSDART00000031139
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4b
chr5_+_63785339 0.30 ENSDART00000050871
regulator of G protein signaling 3b
chr7_+_20031202 0.30 ENSDART00000052904
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr8_+_25247245 0.30 ENSDART00000045798
adenosine monophosphate deaminase 2b
chr14_+_14836468 0.30 ENSDART00000166728
si:dkey-102m7.3
chr16_+_50741154 0.30 ENSDART00000101627
zgc:110372
chr22_-_15569736 0.29 ENSDART00000132334
ankyrin repeat and MYND domain containing 1
chr21_-_20765338 0.29 ENSDART00000135940
growth hormone receptor b
chr18_-_9046805 0.29 ENSDART00000134224
glutamate receptor, metabotropic 3
chr7_+_21752168 0.29 ENSDART00000173641
lysine (K)-specific demethylase 6B, a
chr20_-_27733683 0.29 ENSDART00000103317
ENSDART00000138139
zgc:153157
chr8_-_47329755 0.29 ENSDART00000060853
peroxisomal biogenesis factor 10
chr9_+_42066030 0.29 ENSDART00000185311
ENSDART00000015267
poly(rC) binding protein 3
chr19_+_33732188 0.28 ENSDART00000151192
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr7_+_20030888 0.28 ENSDART00000192808
solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
chr6_+_39184236 0.28 ENSDART00000156187
tachykinin 3b
chr2_+_40294313 0.27 ENSDART00000037292
eph receptor A4b
chr12_-_6159545 0.27 ENSDART00000152487
RAMP-like triterpene glycoside receptor
chr16_-_29458806 0.27 ENSDART00000047931
leucine rich repeat and Ig domain containing 4b
chr14_-_32016615 0.27 ENSDART00000105761
zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)
chr9_+_36314867 0.27 ENSDART00000176763
low density lipoprotein receptor-related protein 1Bb
chr7_+_29167744 0.27 ENSDART00000076345
solute carrier family 38, member 8b
chr9_-_44295071 0.27 ENSDART00000011837
neuronal differentiation 1
chr20_+_19212962 0.26 ENSDART00000063706
fibronectin type III domain containing 4a
chr22_-_17606575 0.26 ENSDART00000183951
glutathione peroxidase 4a
chr6_-_16456093 0.26 ENSDART00000083305
ENSDART00000181640
solute carrier family 19 (thiamine transporter), member 2
chr20_-_5369105 0.26 ENSDART00000114316
serine palmitoyltransferase, long chain base subunit 2b
chr1_-_22834824 0.26 ENSDART00000043556
LIM domain binding 2b
chr5_-_18897482 0.25 ENSDART00000010101
ENSDART00000099434
acetoacetyl-CoA synthetase
chr18_-_5875433 0.25 ENSDART00000151727
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr21_-_2322102 0.24 ENSDART00000162867
zgc:66483
chr9_+_45789887 0.24 ENSDART00000135202
si:dkey-34f9.3
chr13_-_18637244 0.24 ENSDART00000057869
methionine adenosyltransferase I, alpha
chr24_+_2519761 0.24 ENSDART00000106619
neuritin 1a
chr9_-_35557397 0.24 ENSDART00000100681
neural cell adhesion molecule 2
chr25_-_21092222 0.24 ENSDART00000154765
proline rich 5a (renal)
chr2_+_6181383 0.23 ENSDART00000153307
si:ch73-344o19.1
chr10_+_21559605 0.23 ENSDART00000123648
ENSDART00000108584
protocadherin 1 alpha 3
protocadherin 1 alpha 3
chr24_-_8409641 0.23 ENSDART00000149662
ENSDART00000149025
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
chr10_+_23022263 0.23 ENSDART00000138955
si:dkey-175g6.2
chr11_-_3959477 0.23 ENSDART00000045971
polybromo 1
chr6_+_22597362 0.23 ENSDART00000131242
cytoglobin 2
chr22_-_38034852 0.23 ENSDART00000104613
peroxisomal biogenesis factor 6
chr23_+_40452157 0.23 ENSDART00000113106
ENSDART00000140136
SOGA family member 3b
chr25_-_8625601 0.23 ENSDART00000155280
zgc:153343
chr13_-_40316367 0.23 ENSDART00000009343
pyridine nucleotide-disulphide oxidoreductase domain 2
chr4_-_211714 0.22 ENSDART00000172566
protein tyrosine phosphatase, receptor type, O
chr6_+_42819337 0.22 ENSDART00000046498
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa
chr15_-_14469704 0.22 ENSDART00000185077
numb homolog (Drosophila)-like
chr8_+_20438884 0.22 ENSDART00000016422
ENSDART00000133794
MAP kinase interacting serine/threonine kinase 2b
chr18_+_5875268 0.22 ENSDART00000177784
ENSDART00000122009
WD repeat domain 59
chr6_-_44711942 0.22 ENSDART00000055035
contactin 3b
chr11_-_37411492 0.22 ENSDART00000166468
ELKS/RAB6-interacting/CAST family member 2
chr25_+_17689565 0.21 ENSDART00000171965
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18a
chr8_-_19649617 0.21 ENSDART00000189033
family with sequence similarity 78, member B b
chr15_+_43093044 0.21 ENSDART00000141125
potassium voltage-gated channel, Isk-related family, member 4
chr8_-_30979494 0.21 ENSDART00000138959
si:ch211-251j10.3
chr1_-_23588996 0.21 ENSDART00000102600
ligand dependent nuclear receptor corepressor-like
chr3_+_53773256 0.21 ENSDART00000170461
collagen, type V, alpha 3a
chr10_-_6775271 0.20 ENSDART00000110735
zgc:194281
chr18_-_226800 0.20 ENSDART00000165180
threonyl-tRNA synthetase-like 2
chr13_+_18311410 0.20 ENSDART00000036718
ENSDART00000132073
eukaryotic translation initiation factor 4E family member 1c
chr24_-_3783258 0.20 ENSDART00000139596
adenosine deaminase, RNA-specific, B2 (non-functional)
chr12_-_3453589 0.20 ENSDART00000175918

chr19_+_33732487 0.20 ENSDART00000010294
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr19_+_42469058 0.20 ENSDART00000076915
si:dkey-166k12.1
chr5_-_13167097 0.20 ENSDART00000149700
ENSDART00000030213
mitogen-activated protein kinase 1
chr7_-_35126374 0.20 ENSDART00000141211
hydroxysteroid (11-beta) dehydrogenase 2
chr21_-_36948 0.19 ENSDART00000181230
junction mediating and regulatory protein, p53 cofactor
chr12_-_999762 0.19 ENSDART00000127003
ENSDART00000084076
ENSDART00000152425
methyltransferase like 9
chr16_+_10841163 0.19 ENSDART00000065467
death effector domain-containing 1
chr18_+_6126506 0.19 ENSDART00000125725
si:ch1073-390k14.1
chr22_+_3238474 0.19 ENSDART00000157954
si:ch1073-178p5.3
chr5_+_27583445 0.19 ENSDART00000136488
zinc finger, matrin-type 4a
chr12_+_33038757 0.19 ENSDART00000153146
RNA binding fox-1 homolog 3a
chr16_+_36906693 0.19 ENSDART00000160645
si:ch73-215d9.1
chr14_-_46675850 0.19 ENSDART00000113285
transmembrane anterior posterior transformation 1a
chr5_-_45894802 0.18 ENSDART00000097648
cytokine receptor family member b6
chr3_+_17744339 0.18 ENSDART00000132622
zinc finger protein 385C
chr18_+_10784730 0.18 ENSDART00000028938
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr9_-_403767 0.18 ENSDART00000167743
si:dkey-11f4.7
chr5_+_44228526 0.18 ENSDART00000143789
si:dkey-84j12.1
chr3_-_40933415 0.18 ENSDART00000055201
forkhead box K1
chr16_-_21489514 0.17 ENSDART00000149525
ENSDART00000148517
ENSDART00000146914
ENSDART00000186493
ENSDART00000193081
ENSDART00000186017
membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6)
chr11_-_16975190 0.17 ENSDART00000122222
succinate-CoA ligase, GDP-forming, beta subunit
chr17_+_19499157 0.17 ENSDART00000077804
solute carrier family 22, member 15
chr11_-_37880492 0.17 ENSDART00000102868
ethanolamine kinase 2
chr19_-_791016 0.17 ENSDART00000037515
misato 1, mitochondrial distribution and morphology regulator
chr5_-_3839285 0.17 ENSDART00000122292
MLX interacting protein like
chr9_+_32358514 0.17 ENSDART00000144608
phospholipase C like 1
chr22_+_17261801 0.17 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tudor domain containing 5
chr1_+_17376922 0.17 ENSDART00000145068
FAT atypical cadherin 1a
chr19_-_5103313 0.17 ENSDART00000037007
triosephosphate isomerase 1a
chr19_+_9111550 0.17 ENSDART00000088336
SET domain, bifurcated 1a
chr12_+_34827808 0.16 ENSDART00000105533
TEPSIN, adaptor related protein complex 4 accessory protein
chr20_-_22798794 0.16 ENSDART00000148084
FIP1 like 1a (S. cerevisiae)
chr21_-_41588129 0.16 ENSDART00000164125
creb3 regulatory factor
chr14_-_42231293 0.16 ENSDART00000185486

chr20_-_9199721 0.16 ENSDART00000064140
YLP motif containing 1
chr23_+_21459263 0.16 ENSDART00000104209
hairy-related 4, tandem duplicate 3
chr7_+_32021669 0.16 ENSDART00000173976
methyltransferase like 15
chr21_+_1378250 0.16 ENSDART00000186912
transcription factor 4
chr7_+_48999723 0.16 ENSDART00000182699
ENSDART00000166329
si:ch211-288d18.1
chr19_-_30565122 0.16 ENSDART00000185650
hippocalcin like 4
chr2_+_205763 0.16 ENSDART00000160164
ENSDART00000101071
zgc:113293
chr3_+_40841897 0.16 ENSDART00000150081
ENSDART00000126096
monocyte to macrophage differentiation-associated 2a
chr9_+_32872690 0.16 ENSDART00000020798
si:dkey-145p14.5
chr6_-_57476465 0.15 ENSDART00000128065
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr3_-_11972516 0.15 ENSDART00000140123
heme oxygenase 2b
chr5_+_27583117 0.15 ENSDART00000180340
zinc finger, matrin-type 4a
chr4_+_3455665 0.15 ENSDART00000058277
zinc finger protein 800b
chr22_-_38035084 0.15 ENSDART00000145029
peroxisomal biogenesis factor 6
chr15_-_11956981 0.15 ENSDART00000164163
si:dkey-202l22.3
chr12_+_32729470 0.15 ENSDART00000175712
RNA binding fox-1 homolog 3a
chr7_+_29163762 0.15 ENSDART00000173762
solute carrier family 38, member 8b
chr21_-_22122312 0.15 ENSDART00000101726
solute carrier family 35, member F2
chr18_+_38191346 0.15 ENSDART00000052703
nucleobindin 2b
chr4_-_5302866 0.14 ENSDART00000138590
si:ch211-214j24.9

Network of associatons between targets according to the STRING database.

First level regulatory network of hey2_hey1+heyl

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 0.5 GO:0061355 Wnt protein secretion(GO:0061355)
0.1 1.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.5 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.1 0.4 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 0.3 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.1 0.6 GO:1902023 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.1 0.4 GO:0019626 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.1 0.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.3 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 0.3 GO:0009447 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 0.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.5 GO:0030194 acute-phase response(GO:0006953) positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.1 0.2 GO:0042245 RNA repair(GO:0042245)
0.1 0.2 GO:0071435 potassium ion export(GO:0071435) potassium ion export across plasma membrane(GO:0097623)
0.1 0.2 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.1 0.7 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.4 GO:0007141 male meiosis I(GO:0007141)
0.1 1.0 GO:0009749 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.1 0.7 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.0 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.3 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.4 GO:0006567 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.2 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.3 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.7 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.4 GO:0030719 P granule organization(GO:0030719)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.0 0.6 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:1903673 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.0 1.0 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.0 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.1 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.1 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.0 0.3 GO:0045117 azole transport(GO:0045117)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0097037 heme export(GO:0097037)
0.0 0.2 GO:0034650 cortisol metabolic process(GO:0034650)
0.0 0.1 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.0 0.9 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0006788 heme oxidation(GO:0006788)
0.0 0.3 GO:0021754 facial nucleus development(GO:0021754)
0.0 1.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 0.3 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.5 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0019079 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 0.1 GO:0042766 nucleosome mobilization(GO:0042766)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.2 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.0 0.1 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.2 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.2 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0090177 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.1 GO:0070378 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.0 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.0 GO:0072387 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.0 0.1 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.2 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.0 GO:0006585 dopamine biosynthetic process from tyrosine(GO:0006585) dopamine biosynthetic process(GO:0042416)
0.0 0.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.2 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.4 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.0 GO:1900136 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.0 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.3 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.0 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.1 GO:0032094 response to food(GO:0032094)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 1.0 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.7 GO:0016586 RSC complex(GO:0016586)
0.1 1.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.3 GO:0016600 flotillin complex(GO:0016600)
0.1 0.4 GO:0071203 WASH complex(GO:0071203)
0.1 0.4 GO:0070062 extracellular exosome(GO:0070062)
0.1 0.2 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.1 0.2 GO:0033391 chromatoid body(GO:0033391)
0.1 0.2 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:0097268 cytoophidium(GO:0097268)
0.0 1.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0044545 NSL complex(GO:0044545)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0043186 P granule(GO:0043186)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.5 GO:0032589 neuron projection membrane(GO:0032589) dendrite membrane(GO:0032590)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.2 0.7 GO:0004903 growth hormone receptor activity(GO:0004903)
0.1 1.0 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 1.1 GO:0015295 solute:proton symporter activity(GO:0015295)
0.1 0.6 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.3 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 0.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.5 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.4 GO:0008743 L-threonine 3-dehydrogenase activity(GO:0008743)
0.1 0.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.2 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.1 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.2 GO:0043734 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.1 0.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.4 GO:0099583 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.0 0.2 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0052834 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.5 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.5 GO:0022851 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0043531 ADP binding(GO:0043531)
0.0 0.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.0 0.2 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 0.0 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.0 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.0 0.1 GO:0043121 neurotrophin binding(GO:0043121)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.0 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.2 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.3 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 0.4 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.4 GO:0030145 manganese ion binding(GO:0030145)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.0 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells