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PRJNA207719: Tissue specific transcriptome profiling
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Results for gmeb2
Z-value: 0.73
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Transcription factors associated with gmeb2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| GMEB2 | dr11_v1_chr23_-_41824460_41824460 | 0.72 | 1.7e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_-_27381691 Show fit | 0.62 |
ENSDART00000010293
|
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10a |
|
| chr1_-_38815361 Show fit | 0.52 |
ENSDART00000148790
ENSDART00000148572 ENSDART00000149080 |
ankyrin repeat and SOCS box containing 5b |
|
| chr1_+_25801648 Show fit | 0.29 |
ENSDART00000129471
|
guanylate cyclase 1 soluble subunit beta 1 |
|
| chr8_+_1239 Show fit | 0.25 |
ENSDART00000067666
ENSDART00000192564 ENSDART00000192612 ENSDART00000190683 |
transmembrane p24 trafficking protein 7 |
|
| chr19_-_31402429 Show fit | 0.25 |
ENSDART00000137292
|
transmembrane protein 106Bb |
|
| chr2_-_32486080 Show fit | 0.24 |
ENSDART00000110821
|
tetratricopeptide repeat domain 19 |
|
| chr16_+_28596555 Show fit | 0.24 |
ENSDART00000046209
ENSDART00000141708 |
acyl-CoA binding domain containing 7 |
|
| chr11_+_37275448 Show fit | 0.23 |
ENSDART00000161423
|
cysteine-rich with EGF-like domains 1a |
|
| chr5_+_3501859 Show fit | 0.22 |
ENSDART00000080486
|
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1 |
|
| chr19_+_46259619 Show fit | 0.21 |
ENSDART00000158032
|
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1a (glutamate binding) |
Network of associatons between targets according to the STRING database.
First level regulatory network of gmeb2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0099548 | trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548) |
| 0.1 | 0.2 | GO:0021960 | anterior commissure morphogenesis(GO:0021960) |
| 0.0 | 0.2 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
| 0.0 | 0.2 | GO:1902108 | regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108) |
| 0.0 | 0.2 | GO:0021794 | thalamus development(GO:0021794) |
| 0.0 | 0.2 | GO:1902624 | positive regulation of neutrophil migration(GO:1902624) |
| 0.0 | 0.2 | GO:0032418 | lysosome localization(GO:0032418) |
| 0.0 | 0.2 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
| 0.0 | 0.1 | GO:0045040 | outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040) |
| 0.0 | 0.1 | GO:0070221 | sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.1 | 0.2 | GO:0017177 | glucosidase II complex(GO:0017177) |
| 0.0 | 0.1 | GO:0070695 | FHF complex(GO:0070695) |
| 0.0 | 0.1 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 0.0 | 0.1 | GO:0045293 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 0.0 | 0.1 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 0.0 | 0.1 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.1 | GO:0001401 | mitochondrial sorting and assembly machinery complex(GO:0001401) |
| 0.0 | 0.1 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.0 | 0.1 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 0.0 | 0.3 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.1 | 0.2 | GO:0004301 | epoxide hydrolase activity(GO:0004301) |
| 0.0 | 0.2 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
| 0.0 | 0.2 | GO:0004060 | arylamine N-acetyltransferase activity(GO:0004060) |
| 0.0 | 0.2 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 0.2 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) |
| 0.0 | 0.2 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.0 | 0.2 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.0 | 0.2 | GO:0031682 | G-protein gamma-subunit binding(GO:0031682) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.0 | 0.1 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 0.1 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |