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PRJNA207719: Tissue specific transcriptome profiling
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Results for gli2a+gli3
Z-value: 1.09
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Transcription factors associated with gli2a+gli3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| gli2a | dr11_v1_chr9_+_37141836_37141836 | -0.93 | 2.2e-02 | Click! |
| gli3 | dr11_v1_chr24_-_11821505_11821505 | -0.68 | 2.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr22_-_24858042 Show fit | 1.50 |
ENSDART00000137998
ENSDART00000078216 ENSDART00000138378 |
vitellogenin 7 |
|
| chr1_-_19845378 Show fit | 1.26 |
ENSDART00000139314
ENSDART00000132958 ENSDART00000147502 |
glyoxylate reductase/hydroxypyruvate reductase b |
|
| chr22_+_38173960 Show fit | 1.01 |
ENSDART00000010537
|
ceruloplasmin |
|
| chr22_-_24818066 Show fit | 1.00 |
ENSDART00000143443
|
vitellogenin 6 |
|
| chr16_+_52512025 Show fit | 0.99 |
ENSDART00000056095
|
fatty acid binding protein 10a, liver basic |
|
| chr10_+_26747755 Show fit | 0.98 |
ENSDART00000100329
|
coagulation factor IXb |
|
| chr25_-_17403598 Show fit | 0.88 |
ENSDART00000104216
|
cytochrome P450, family 2, subfamily X, polypeptide 9 |
|
| chr22_-_24791505 Show fit | 0.86 |
ENSDART00000136837
|
vitellogenin 4 |
|
| chr5_-_43959972 Show fit | 0.70 |
ENSDART00000180517
|
si:ch211-204c21.1 |
|
| chr4_+_72797711 Show fit | 0.67 |
ENSDART00000190934
ENSDART00000163236 |
myelin regulatory factor-like |
Network of associatons between targets according to the STRING database.
First level regulatory network of gli2a+gli3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.0 | GO:0032355 | response to estradiol(GO:0032355) |
| 0.0 | 1.0 | GO:0007596 | blood coagulation(GO:0007596) |
| 0.1 | 0.9 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.0 | 0.9 | GO:0042738 | drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738) |
| 0.0 | 0.7 | GO:0045807 | positive regulation of endocytosis(GO:0045807) |
| 0.1 | 0.5 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
| 0.0 | 0.3 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.0 | 0.3 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 0.3 | GO:0007032 | endosome organization(GO:0007032) |
| 0.0 | 0.3 | GO:0006884 | cell volume homeostasis(GO:0006884) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0045277 | respiratory chain complex IV(GO:0045277) |
| 0.0 | 0.2 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.0 | 0.2 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.0 | 0.1 | GO:0043514 | interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743) |
| 0.0 | 0.1 | GO:0001650 | fibrillar center(GO:0001650) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 3.4 | GO:0045735 | nutrient reservoir activity(GO:0045735) |
| 0.4 | 1.3 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.2 | 1.0 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.1 | 1.0 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.0 | 0.9 | GO:0016712 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712) |
| 0.1 | 0.7 | GO:0000048 | peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374) |
| 0.1 | 0.5 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.1 | 0.4 | GO:0050508 | glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508) |
| 0.0 | 0.4 | GO:0005003 | ephrin receptor activity(GO:0005003) |
| 0.0 | 0.4 | GO:0015002 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 0.3 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
| 0.0 | 0.3 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.0 | 0.2 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 0.2 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 0.1 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |