ISMARA results: gbx2

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PRJNA207719: Tissue specific transcriptome profiling

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Results for gbx2

Z-value: 0.49

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Transcription factors associated with gbx2

Gene Symbol	Gene ID	Gene Info
gbx2 NCBI UniProt	ENSDARG00000002933	gastrulation brain homeobox 2
gbx2 NCBI UniProt	ENSDARG00000116377	gastrulation brain homeobox 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
gbx2	dr11_v1_chr6_+_16031189_16031189	0.69	2.0e-01	Click!

Activity profile of gbx2 motif

Sorted Z-values of gbx2 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr3_-_21037840 Show fit	0.26	ENSDART00000002393	rundc3aa NCBI UniProt Show fit	RUN domain containing 3Aa
chr18_+_26895994 Show fit	0.25	ENSDART00000098347	ch25hl1.2 NCBI UniProt Show fit	cholesterol 25-hydroxylase like 1, tandem duplicate 2
chr8_+_31821396 Show fit	0.22	ENSDART00000077053	plcxd3 NCBI UniProt Show fit	phosphatidylinositol-specific phospholipase C, X domain containing 3
chr11_+_24620742 Show fit	0.22	ENSDART00000182471 ENSDART00000048365	syt6b NCBI UniProt Show fit	synaptotagmin VIb
chr12_-_35386910 Show fit	0.22	ENSDART00000153453	camk2g1 NCBI UniProt Show fit	calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr10_-_34741738 Show fit	0.21	ENSDART00000163072	dclk1a NCBI UniProt Show fit	doublecortin-like kinase 1a
chr18_+_17537344 Show fit	0.20	ENSDART00000025782	nup93 NCBI UniProt Show fit	nucleoporin 93
chr17_+_51499789 Show fit	0.19	ENSDART00000187701	CABZ01067581.1 NCBI UniProt Show fit
chr5_+_30624183 Show fit	0.18	ENSDART00000141444	abcg4a NCBI UniProt Show fit	ATP-binding cassette, sub-family G (WHITE), member 4a
chr4_-_5019113 Show fit	0.18	ENSDART00000189321 ENSDART00000081990	strip2 NCBI UniProt Show fit	striatin interacting protein 2

Showing 1 to 10 of 104 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of gbx2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Total log-likelihood	Term	Description
0.4	GO:0055117	regulation of cardiac muscle contraction(GO:0055117)
0.3	GO:0010752	regulation of cGMP-mediated signaling(GO:0010752)
0.2	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.2	GO:0032289	central nervous system myelin formation(GO:0032289)
0.2	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2	GO:2000601	positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1	GO:0071361	cellular response to ethanol(GO:0071361)
0.1	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.1	GO:0060282	positive regulation of oocyte development(GO:0060282)

Showing 1 to 10 of 18 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	GO:0098982	GABA-ergic synapse(GO:0098982)
0.0	0.1	GO:0070847	core mediator complex(GO:0070847)

Showing 1 to 2 of 2 entries

Gene overrepresentation in molecular function category:

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Total log-likelihood	Term	Description
0.3	GO:0000254	C-4 methylsterol oxidase activity(GO:0000254)
0.2	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.2	GO:0016405	CoA-ligase activity(GO:0016405)
0.2	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1	GO:0031835	neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.1	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.1	GO:0003938	IMP dehydrogenase activity(GO:0003938)
0.1	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.1	GO:0000035	acyl binding(GO:0000035)
0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)

Showing 1 to 10 of 10 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors

Showing 1 to 1 of 1 entries

Results for gbx2

Z-value: 0.49

Motif logo

Transcription factors associated with gbx2

Activity-expression correlation:

Activity profile of gbx2 motif

Sorted Z-values of gbx2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of gbx2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: