ISMARA results: foxo3b+foxo6a+foxo6b

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PRJNA207719: Tissue specific transcriptome profiling

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Results for foxo3b+foxo6a+foxo6b

Z-value: 0.26

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Transcription factors associated with foxo3b+foxo6a+foxo6b

Gene Symbol	Gene ID	Gene Info
foxo6b NCBI UniProt	ENSDARG00000024619	forkhead box O6 b
foxo3b NCBI UniProt	ENSDARG00000042904	forkhead box O3b
foxo6a NCBI UniProt	ENSDARG00000100486	forkhead box O6 a

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
foxo6b	dr11_v1_chr19_+_15571290_15571290	-0.53	3.6e-01	Click!
foxo6a	dr11_v1_chr16_-_7362806_7362806	-0.44	4.6e-01	Click!
foxo3b	dr11_v1_chr20_-_32332736_32332736	-0.36	5.5e-01	Click!

Activity profile of foxo3b+foxo6a+foxo6b motif

Sorted Z-values of foxo3b+foxo6a+foxo6b motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr3_+_19299309 Show fit	0.13	ENSDART00000046297 ENSDART00000146955	ldlra NCBI UniProt Show fit	low density lipoprotein receptor a
chr20_-_33583779 Show fit	0.13	ENSDART00000097823	rock2b NCBI UniProt Show fit	rho-associated, coiled-coil containing protein kinase 2b
chr12_+_31713239 Show fit	0.12	ENSDART00000122379	habp2 NCBI UniProt Show fit	hyaluronan binding protein 2
chr2_+_10134345 Show fit	0.11	ENSDART00000100725	ahsg2 NCBI UniProt Show fit	alpha-2-HS-glycoprotein 2
chr5_+_46196147 Show fit	0.09	ENSDART00000084112	f2r NCBI UniProt Show fit	coagulation factor II (thrombin) receptor
chr19_-_30447611 Show fit	0.08	ENSDART00000073705 ENSDART00000048977 ENSDART00000191237	abcf1 NCBI UniProt Show fit	ATP-binding cassette, sub-family F (GCN20), member 1
chr2_+_44571200 Show fit	0.08	ENSDART00000098132	klhl24a NCBI UniProt Show fit	kelch-like family member 24a
chr5_+_29652513 Show fit	0.07	ENSDART00000035400	tsc1a NCBI UniProt Show fit	TSC complex subunit 1a
chr22_+_25753972 Show fit	0.07	ENSDART00000188417	AL929192.2 NCBI UniProt Show fit
chr23_+_17417539 Show fit	0.07	ENSDART00000182605	BX649300.2 NCBI UniProt Show fit

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of foxo3b+foxo6a+foxo6b

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Total log-likelihood	Term	Description
0.1	GO:1901533	negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.1	GO:0032367	intracellular cholesterol transport(GO:0032367)
0.1	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1	GO:2000312	regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0	GO:0031591	wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0	GO:0019878	lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.0	GO:0000212	meiotic spindle organization(GO:0000212)

Showing 1 to 7 of 7 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	GO:0033596	TSC1-TSC2 complex(GO:0033596)

Showing 1 to 1 of 1 entries

Gene overrepresentation in molecular function category:

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Total log-likelihood	Term	Description
0.1	GO:0030228	lipoprotein particle receptor activity(GO:0030228)
0.1	GO:0072518	Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	GO:0017040	ceramidase activity(GO:0017040)

Showing 1 to 4 of 4 entries

Results for foxo3b+foxo6a+foxo6b

Z-value: 0.26

Motif logo

Transcription factors associated with foxo3b+foxo6a+foxo6b

Activity-expression correlation:

Activity profile of foxo3b+foxo6a+foxo6b motif

Sorted Z-values of foxo3b+foxo6a+foxo6b motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of foxo3b+foxo6a+foxo6b

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: