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PRJNA207719: Tissue specific transcriptome profiling

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Results for foxn1

Z-value: 1.77

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Transcription factors associated with foxn1

Gene Symbol Gene ID Gene Info
ENSDARG00000011879 forkhead box N1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxn1dr11_v1_chr15_-_28161224_28161224-0.405.1e-01Click!

Activity profile of foxn1 motif

Sorted Z-values of foxn1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_21832441 1.72 ENSDART00000151272
ENSDART00000151442
ENSDART00000150168
ENSDART00000148797
ENSDART00000128196
ENSDART00000149259
ENSDART00000052556
ENSDART00000149658
ENSDART00000149639
ENSDART00000148424
myelin basic protein a
chr13_-_51247529 1.26 ENSDART00000191774
ENSDART00000083788

chr5_-_31901468 1.22 ENSDART00000147814
ENSDART00000141446
coronin, actin binding protein, 1Cb
chr7_+_23907692 1.16 ENSDART00000045479
synaptotagmin IV
chr23_+_19590006 1.13 ENSDART00000021231
sarcolemma associated protein b
chr12_-_19103490 1.06 ENSDART00000060561
cold shock domain containing C2, RNA binding a
chr17_+_29345606 1.06 ENSDART00000086164
potassium channel tetramerization domain containing 3
chr25_+_12640211 1.06 ENSDART00000165108
junctophilin 3
chr1_+_19930520 1.00 ENSDART00000158344
amyloid beta (A4) precursor protein-binding, family B, member 2b
chr3_-_35602233 0.99 ENSDART00000055269
guanine nucleotide binding protein (G protein), gamma 13b
chr3_+_33340939 0.96 ENSDART00000128786
peptide YYa
chr19_-_27966526 0.95 ENSDART00000141896
ubiquitin-conjugating enzyme E2Q family-like 1
chr17_-_46457622 0.93 ENSDART00000130215
transmembrane protein 179
chr7_+_23495986 0.93 ENSDART00000190739
ENSDART00000115299
ENSDART00000101423
ENSDART00000142401
zgc:109889
chr1_+_41690402 0.88 ENSDART00000177298
F-box protein 41
chr21_+_3093419 0.88 ENSDART00000162520
SHC adaptor protein 3
chr24_-_38374744 0.87 ENSDART00000007208
leucine rich repeat containing 4Bb
chr21_-_14251306 0.86 ENSDART00000114715
ENSDART00000181380
mannosidase, alpha, class 1B, member 1a
chr15_-_22147860 0.84 ENSDART00000149784
sodium channel, voltage-gated, type III, beta
chr4_-_8152746 0.83 ENSDART00000012928
ENSDART00000177482
WNK lysine deficient protein kinase 1b
chr19_-_27966780 0.82 ENSDART00000110016
ubiquitin-conjugating enzyme E2Q family-like 1
chr14_+_8275115 0.82 ENSDART00000129055
neuregulin 2b
chr8_+_6967108 0.81 ENSDART00000004588
acid-sensing (proton-gated) ion channel 1a
chr4_+_2619132 0.80 ENSDART00000128807
G protein-coupled receptor 22a
chr12_+_26467847 0.80 ENSDART00000022495
nudE neurodevelopment protein 1-like 1a
chr11_+_6819050 0.79 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr13_-_50672341 0.79 ENSDART00000190498

chr18_-_39787040 0.79 ENSDART00000169916
Dmx-like 2
chr10_+_37500234 0.77 ENSDART00000132096
ENSDART00000099473
musashi RNA-binding protein 2a
chr6_+_51932267 0.77 ENSDART00000156256
angiopoietin 4
chr15_-_15449929 0.74 ENSDART00000101918
protein interacting with cyclin A1
chr17_-_7861219 0.73 ENSDART00000148604
spectrin repeat containing, nuclear envelope 1b
chr1_+_33969015 0.73 ENSDART00000042984
ENSDART00000146530
eph receptor A6
chr10_+_21668606 0.72 ENSDART00000185751

chr23_-_27345425 0.72 ENSDART00000022042
ENSDART00000191870
sodium channel, voltage gated, type VIII, alpha subunit a
chr7_+_69528850 0.72 ENSDART00000109507
Rap1 GTPase-GDP dissociation stimulator 1
chr21_-_43606502 0.72 ENSDART00000151030
si:ch73-362m14.4
chr11_-_38083397 0.68 ENSDART00000086516
ENSDART00000184033
kelch domain containing 8A
chr12_+_9703172 0.68 ENSDART00000091489
protein phosphatase 1, regulatory subunit 9Bb
chr8_+_668184 0.65 ENSDART00000183788
ring finger protein 165b
chr14_-_2361692 0.65 ENSDART00000167696
si:ch73-233f7.4
chr11_+_23933016 0.64 ENSDART00000000486
contactin 2
chr23_-_10786400 0.63 ENSDART00000055038
RING1 and YY1 binding protein a
chr8_+_36500061 0.63 ENSDART00000185840
solute carrier family 7, member 4
chr4_-_12102025 0.63 ENSDART00000048391
ENSDART00000023894
B-Raf proto-oncogene, serine/threonine kinase
chr16_+_50741154 0.63 ENSDART00000101627
zgc:110372
chr17_+_44780166 0.62 ENSDART00000156260
transmembrane protein 63C
chr2_-_6292510 0.62 ENSDART00000092182
protein phosphatase, Mg2+/Mn2+ dependent, 1La
chr6_-_42377307 0.62 ENSDART00000129302
ER membrane protein complex subunit 3
chr7_+_22801465 0.62 ENSDART00000052862
ENSDART00000173633
RNA binding motif protein 4.1
chr8_+_52530889 0.61 ENSDART00000127729
ENSDART00000170360
ENSDART00000162687
STAM binding protein b
chr20_+_52442870 0.61 ENSDART00000163100
Rho GTPase activating protein 39
chr17_-_45552602 0.60 ENSDART00000154844
ENSDART00000034432
sushi domain containing 4
chr17_+_37301860 0.60 ENSDART00000181531
ENSDART00000075978
ELM2 and Myb/SANT-like domain containing 1b
chr23_+_23485858 0.60 ENSDART00000114067
agrin
chr20_-_28884800 0.59 ENSDART00000134564
ENSDART00000132127
ENSDART00000135506
ENSDART00000075515
serine/arginine-rich splicing factor 5b
chr6_+_51932563 0.59 ENSDART00000181778
angiopoietin 4
chr13_+_2442841 0.59 ENSDART00000114456
ENSDART00000137124
ENSDART00000193737
ENSDART00000189722
ENSDART00000187485
ARFGEF family member 3
chr15_+_19335646 0.59 ENSDART00000062569
acyl-CoA dehydrogenase family, member 8
chr23_-_35347714 0.59 ENSDART00000161770
ENSDART00000165615
copine family member IX
chr19_+_5134624 0.57 ENSDART00000151324
si:dkey-89b17.4
chr5_-_29643381 0.56 ENSDART00000034849
glutamate receptor, ionotropic, N-methyl D-aspartate 1b
chr1_-_21483832 0.55 ENSDART00000102790
glycine receptor, beta a
chr18_+_328689 0.55 ENSDART00000167841
synovial sarcoma translocation gene on chromosome 18-like 2
chr8_+_54055390 0.54 ENSDART00000102696
membrane associated guanylate kinase, WW and PDZ domain containing 1a
chr16_-_27161410 0.54 ENSDART00000177503

chr12_-_25150239 0.53 ENSDART00000038415
ENSDART00000135368
ras homolog family member Q
chr8_-_18582922 0.52 ENSDART00000123917
transmembrane protein 47
chr12_-_35988586 0.50 ENSDART00000157746
phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b
chr24_-_18179535 0.50 ENSDART00000186112
contactin associated protein like 2a
chr3_+_34919810 0.50 ENSDART00000055264
carbonic anhydrase Xb
chr24_-_29997145 0.50 ENSDART00000135094
palmdelphin b
chr2_+_37480669 0.49 ENSDART00000029801
signal peptide peptidase-like 2
chr6_+_6491013 0.48 ENSDART00000140827
B cell CLL/lymphoma 11Ab
chr13_+_51579851 0.48 ENSDART00000163847
NK6 homeobox 2
chr8_+_35172594 0.48 ENSDART00000177146

chr16_+_23282655 0.47 ENSDART00000015956
ephrin-A1b
chr19_+_5135113 0.47 ENSDART00000151310
si:dkey-89b17.4
chr2_+_6127593 0.46 ENSDART00000184007
fizzy/cell division cycle 20 related 1b
chr12_-_4632519 0.46 ENSDART00000110514
proline rich 12a
chr16_-_7362806 0.46 ENSDART00000166776
forkhead box O6 a
chr13_+_24287093 0.46 ENSDART00000058628
centriole, cilia and spindle-associated protein b
chr25_-_25142387 0.46 ENSDART00000031814
tumor susceptibility 101a
chr17_+_43032529 0.46 ENSDART00000055611
ENSDART00000154863
iron-sulfur cluster assembly 2
chr7_-_19146925 0.45 ENSDART00000142924
ENSDART00000009695
kirre like nephrin family adhesion molecule 1a
chr7_-_18168493 0.45 ENSDART00000127428
pellino E3 ubiquitin protein ligase family member 3
chr16_-_6205790 0.45 ENSDART00000038495
catenin (cadherin-associated protein), beta 1
chr12_-_13318944 0.44 ENSDART00000152201
ENSDART00000041394
ER membrane protein complex subunit 9
chr6_+_10450000 0.44 ENSDART00000151288
ENSDART00000187431
ENSDART00000192474
ENSDART00000188214
ENSDART00000184766
ENSDART00000190082
potassium channel, voltage gated eag related subfamily H, member 7
chr5_-_52216170 0.44 ENSDART00000158542
ENSDART00000192981
leucyl/cystinyl aminopeptidase
chr15_+_15516612 0.44 ENSDART00000016024
tnf receptor-associated factor 4a
chr8_-_24113575 0.44 ENSDART00000099692
ENSDART00000186211
DNA cross-link repair 1B
chr8_+_36503797 0.43 ENSDART00000184785
solute carrier family 7, member 4
chr5_-_19932621 0.43 ENSDART00000088881
G protein-coupled receptor kinase interacting ArfGAP 2a
chr2_-_16359042 0.42 ENSDART00000057216
Rho guanine nucleotide exchange factor (GEF) 4
chr22_+_26703026 0.42 ENSDART00000158756
CREB binding protein a
chr1_+_34295925 0.42 ENSDART00000075584
potassium channel tetramerisation domain containing 12.2
chr5_+_36415978 0.42 ENSDART00000084464
family with sequence similarity 155, member B
chr11_-_23687158 0.42 ENSDART00000189599
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr13_+_2448251 0.42 ENSDART00000188361
ARFGEF family member 3
chr20_-_6196989 0.42 ENSDART00000013343
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr11_-_5563498 0.41 ENSDART00000160835
peroxisomal biogenesis factor 11 gamma
chr15_+_2421432 0.41 ENSDART00000193772
hephaestin-like 1a
chr7_-_47850702 0.41 ENSDART00000109511
si:ch211-186j3.6
chr9_-_24046287 0.40 ENSDART00000184313
atypical chemokine receptor 3a
chr10_+_18877362 0.40 ENSDART00000138334
protein phosphatase 2, regulatory subunit B, alpha b
chr10_+_42374957 0.39 ENSDART00000147926
zgc:86599
chr20_-_31808779 0.39 ENSDART00000133788
syntaxin binding protein 5a (tomosyn)
chr13_-_25284716 0.39 ENSDART00000039828
vinculin a
chr3_+_15773991 0.39 ENSDART00000089923
zinc finger protein 652
chr21_+_1119046 0.39 ENSDART00000184678

chr15_+_2421729 0.38 ENSDART00000082294
ENSDART00000156428
hephaestin-like 1a
chr16_+_23531583 0.38 ENSDART00000146708
adenosine deaminase, RNA-specific
chr17_+_10593398 0.38 ENSDART00000168897
ENSDART00000193989
ENSDART00000191664
ENSDART00000167188
mitogen-activated protein kinase binding protein 1
chr1_+_34203817 0.38 ENSDART00000191432
ENSDART00000046094
ADP-ribosylation factor-like 6
chr13_+_35925490 0.38 ENSDART00000046115
major facilitator superfamily domain containing 2aa
chr3_-_60571218 0.38 ENSDART00000178981
si:ch73-366l1.5
chr20_-_18915376 0.38 ENSDART00000063725
XK, Kell blood group complex subunit-related family, member 6b
chr8_-_43158486 0.38 ENSDART00000134801
coiled-coil domain containing 92
chr3_-_22216771 0.37 ENSDART00000130546
microtubule-associated protein tau b
chr5_+_11812089 0.36 ENSDART00000111359
F-box protein 21
chr23_+_17354951 0.36 ENSDART00000189467
zgc:194282
chr4_-_1497384 0.36 ENSDART00000093236
zmp:0000000711
chr19_+_7173613 0.36 ENSDART00000001331
hydroxysteroid (17-beta) dehydrogenase 8
chr1_-_25144439 0.36 ENSDART00000132355
F-box and WD repeat domain containing 7
chr4_+_12013043 0.35 ENSDART00000130692
cryptochrome circadian clock 1aa
chr1_-_45041272 0.35 ENSDART00000190615
SMU1, DNA replication regulator and spliceosomal factor b
chr13_-_30645965 0.34 ENSDART00000109307
zinc finger, CCHC domain containing 24
chr17_-_8656155 0.34 ENSDART00000148990
C-terminal binding protein 2a
chr6_+_39493864 0.33 ENSDART00000086263
methyltransferase like 7A
chr7_+_40083601 0.33 ENSDART00000099046
zgc:112356
chr7_+_31145386 0.32 ENSDART00000075407
ENSDART00000169462
family with sequence similarity 189, member A1
chr25_+_2776511 0.32 ENSDART00000115280
neogenin 1b
chr8_-_25846188 0.31 ENSDART00000128829
EF-hand domain family, member D2
chr11_-_37425407 0.31 ENSDART00000160911
ELKS/RAB6-interacting/CAST family member 2
chr9_+_34221997 0.31 ENSDART00000028617
mitochondrial pyruvate carrier 2
chr7_+_21859337 0.31 ENSDART00000159626
si:dkey-85k7.7
chr24_+_19210001 0.30 ENSDART00000179373
ENSDART00000139299
zgc:162928
chr9_+_21793565 0.30 ENSDART00000134915
REV1, polymerase (DNA directed)
chr2_+_16696052 0.30 ENSDART00000022356
ENSDART00000164329
protein phosphatase 1, regulatory (inhibitor) subunit 7
chr15_+_2559875 0.30 ENSDART00000178505
SH2B adaptor protein 2
chr1_+_31725154 0.30 ENSDART00000112333
ENSDART00000189801
cyclin and CBS domain divalent metal cation transport mediator 2b
chr21_-_14175838 0.30 ENSDART00000111659
whirlin a
chr1_-_54063520 0.30 ENSDART00000171722
single-pass membrane protein with aspartate-rich tail 1b
chr5_-_52215926 0.29 ENSDART00000163973
ENSDART00000193602
leucyl/cystinyl aminopeptidase
chr9_-_28399071 0.29 ENSDART00000104317
ENSDART00000064343
Kruppel-like factor 7b
chr19_+_19512515 0.29 ENSDART00000180065
JAZF zinc finger 1a
chr1_-_6494384 0.29 ENSDART00000109356
Kruppel-like factor 7a
chr12_+_49100365 0.29 ENSDART00000171905

chr2_-_56131312 0.29 ENSDART00000097755
JunD proto-oncogene, AP-1 transcription factor subunit
chr18_+_19990412 0.29 ENSDART00000155054
ENSDART00000090310
protein inhibitor of activated STAT, 1b
chr7_+_66884291 0.29 ENSDART00000187499
SET binding factor 2
chr2_-_2096055 0.28 ENSDART00000126566
solute carrier family 22, member 23
chr9_-_48296469 0.28 ENSDART00000058255
Bardet-Biedl syndrome 5
chr21_+_21279159 0.28 ENSDART00000148346
inositol-trisphosphate 3-kinase Ca
chr7_-_12869545 0.28 ENSDART00000163045
SH3-domain GRB2-like 3a
chr2_+_42871831 0.28 ENSDART00000171393
EFR3 homolog A (S. cerevisiae)
chr16_+_48460873 0.28 ENSDART00000159902
exostosin glycosyltransferase 1a
chr7_+_17782436 0.28 ENSDART00000173793
ENSDART00000165110
si:dkey-28a3.2
chr22_-_11614973 0.27 ENSDART00000063135
phosphate cytidylyltransferase 2, ethanolamine
chr13_+_19884631 0.27 ENSDART00000089533
attractin-like 1a
chr21_-_35325466 0.27 ENSDART00000134780
ENSDART00000145930
ENSDART00000076715
ENSDART00000065341
ENSDART00000162189
ubiquitin-like domain containing CTD phosphatase 1
chr20_-_50014936 0.27 ENSDART00000148892
exostosin-like glycosyltransferase 3
chr25_-_16782394 0.27 ENSDART00000019413
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9a
chr16_+_20871021 0.26 ENSDART00000006429
3-hydroxyisobutyrate dehydrogenase b
chr5_+_54585431 0.26 ENSDART00000171225
natriuretic peptide receptor 2
chr10_+_36695597 0.26 ENSDART00000169015
ENSDART00000171392
RAB6A, member RAS oncogene family
chr23_+_27652906 0.25 ENSDART00000077931
wingless-type MMTV integration site family, member 1
chr17_-_53022822 0.25 ENSDART00000103434
zgc:154061
chr25_+_36405021 0.25 ENSDART00000152801
ankyrin repeat domain 27 (VPS9 domain)
chr12_-_19151708 0.25 ENSDART00000057124
thyrotrophic embryonic factor a
chr19_+_20163826 0.25 ENSDART00000090942
ENSDART00000134650
coiled-coil domain containing 126
chr3_+_17951790 0.25 ENSDART00000164663
ATP citrate lyase a
chr17_-_23895026 0.25 ENSDART00000122108
PDZ domain containing 8
chr5_+_26075230 0.24 ENSDART00000098473
Kruppel-like factor 9
chr20_-_4738101 0.23 ENSDART00000050201
ENSDART00000152559
ENSDART00000053858
ENSDART00000125620
poly(A) polymerase alpha
chr19_+_26681848 0.23 ENSDART00000138322
si:dkey-27c15.3
chr3_-_29891456 0.23 ENSDART00000151677
ENSDART00000014021
solute carrier family 25, member 39
chr12_-_10674606 0.23 ENSDART00000157919
mediator complex subunit 24
chr13_+_21779975 0.23 ENSDART00000021556
si:ch211-51a6.2
chr1_-_41982582 0.23 ENSDART00000014678
adrenoceptor alpha 1D
chr11_-_19694334 0.23 ENSDART00000054735
si:dkey-30j16.3
chr25_+_4660639 0.23 ENSDART00000130299
DEAF1 transcription factor
chr2_+_44615000 0.22 ENSDART00000188826
ENSDART00000113232
YEATS domain containing 2
chr15_+_404891 0.22 ENSDART00000155682
nipsnap homolog 2
chr7_+_66884570 0.22 ENSDART00000082664
SET binding factor 2
chr1_-_45341760 0.22 ENSDART00000149183
ENSDART00000148289
ENSDART00000110390
zgc:101679
chr10_+_29137482 0.22 ENSDART00000178280
phosphatidylinositol binding clathrin assembly protein a
chr7_-_29571615 0.22 ENSDART00000019140
RAR-related orphan receptor A, paralog b
chr6_+_50381347 0.22 ENSDART00000055504
cytochrome c-1
chr6_-_35106425 0.22 ENSDART00000165139
nitric oxide synthase 1 (neuronal) adaptor protein a
chr1_+_40237276 0.21 ENSDART00000037553
fatty acid amide hydrolase 2a
chr15_-_23908779 0.21 ENSDART00000088808
ubiquitin specific peptidase 32
chr7_+_24006875 0.21 ENSDART00000033755
homeobox and leucine zipper encoding b
chr17_-_16324565 0.21 ENSDART00000030835
homeobox containing 1a
chr8_+_18010568 0.21 ENSDART00000121984
single stranded DNA binding protein 3b
chr8_-_49701904 0.21 ENSDART00000142115
FERM domain containing 3
chr13_-_27916439 0.21 ENSDART00000139081
ENSDART00000087097
opioid growth factor receptor-like 1
chr8_+_27555314 0.21 ENSDART00000135568
ENSDART00000016696
ras homolog family member Cb
chr20_+_54333774 0.21 ENSDART00000144633
CLOCK-interacting pacemaker b

Network of associatons between targets according to the STRING database.

First level regulatory network of foxn1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.3 0.8 GO:0032847 regulation of cellular pH reduction(GO:0032847) synaptic vesicle lumen acidification(GO:0097401) regulation of synaptic vesicle lumen acidification(GO:1901546)
0.2 0.6 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.2 0.8 GO:0086005 ventricular cardiac muscle cell action potential(GO:0086005)
0.2 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957) regulation of protein activation cascade(GO:2000257)
0.2 0.6 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.2 0.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.4 GO:2000055 positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000055)
0.1 0.8 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.5 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 0.4 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of neurological system process(GO:0031645)
0.1 0.8 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.6 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.5 GO:0086011 membrane repolarization during action potential(GO:0086011) membrane repolarization during cardiac muscle cell action potential(GO:0086013) cardiac muscle cell membrane repolarization(GO:0099622)
0.1 0.4 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.5 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.1 1.0 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.4 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 0.5 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.1 0.6 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.1 0.3 GO:1901006 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.1 0.6 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.1 0.4 GO:0031627 telomeric loop formation(GO:0031627)
0.1 0.5 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 0.5 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.3 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 0.4 GO:0016559 peroxisome fission(GO:0016559)
0.1 0.3 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.7 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.2 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 0.8 GO:1901381 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:1903358 regulation of Golgi organization(GO:1903358)
0.0 0.3 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.3 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0 0.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.0 0.8 GO:0006825 copper ion transport(GO:0006825)
0.0 0.9 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.6 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0021634 optic nerve formation(GO:0021634)
0.0 0.1 GO:0072019 proximal convoluted tubule development(GO:0072019)
0.0 1.0 GO:0007631 feeding behavior(GO:0007631)
0.0 0.5 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.4 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.2 GO:0090660 cerebrospinal fluid circulation(GO:0090660)
0.0 0.2 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.4 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.3 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0060043 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.8 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.7 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.2 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.1 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.4 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.7 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 1.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.1 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.3 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.7 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.5 GO:0021986 habenula development(GO:0021986)
0.0 0.4 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.2 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.8 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.4 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.4 GO:0050708 regulation of protein secretion(GO:0050708)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0035777 pronephric distal tubule development(GO:0035777)
0.0 1.1 GO:0006865 amino acid transport(GO:0006865)
0.0 0.3 GO:0016925 protein sumoylation(GO:0016925)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0043291 RAVE complex(GO:0043291)
0.1 0.5 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.5 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 1.6 GO:0031209 SCAR complex(GO:0031209)
0.1 1.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.7 GO:0043209 myelin sheath(GO:0043209)
0.1 0.4 GO:0005913 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.5 GO:0033010 paranodal junction(GO:0033010)
0.1 1.6 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0090443 FAR/SIN/STRIPAK complex(GO:0090443)
0.0 0.3 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.8 GO:0005844 polysome(GO:0005844)
0.0 0.3 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.0 GO:0097255 R2TP complex(GO:0097255)
0.0 0.3 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.4 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.3 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.3 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0031841 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.2 1.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 0.8 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.4 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.1 1.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.8 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.5 GO:1990757 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.1 0.9 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.3 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.6 GO:0032977 membrane insertase activity(GO:0032977)
0.1 0.3 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 0.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.6 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.2 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.1 0.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.8 GO:0019869 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 1.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 1.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.0 0.6 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.6 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.6 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.4 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 1.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0050218 propionate-CoA ligase activity(GO:0050218)
0.0 0.7 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.6 GO:0048038 quinone binding(GO:0048038)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.6 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.4 GO:0015026 coreceptor activity(GO:0015026)
0.0 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.9 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.4 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 1.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.4 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.9 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 1.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.6 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs