ISMARA results: foxl1

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PRJNA207719: Tissue specific transcriptome profiling

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Results for foxl1

Z-value: 0.95

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Transcription factors associated with foxl1

Gene Symbol	Gene ID	Gene Info
foxl1 NCBI UniProt	ENSDARG00000008133	forkhead box L1
foxl1 NCBI UniProt	ENSDARG00000111418	forkhead box L1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
foxl1	dr11_v1_chr18_-_17485419_17485419	0.85	6.8e-02	Click!

Activity profile of foxl1 motif

Sorted Z-values of foxl1 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr6_+_28124393 Show fit	0.79	ENSDART00000089195	gpr17 NCBI UniProt Show fit	G protein-coupled receptor 17
chr13_+_35745572 Show fit	0.77	ENSDART00000159690	gpr75 NCBI UniProt Show fit	G protein-coupled receptor 75
chr11_+_22374419 Show fit	0.68	ENSDART00000174683 ENSDART00000170521 ENSDART00000193980	ppfia4 NCBI UniProt Show fit	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr1_-_54718863 Show fit	0.61	ENSDART00000122601	pgam1b NCBI UniProt Show fit	phosphoglycerate mutase 1b
chr2_+_47581997 Show fit	0.61	ENSDART00000112579	scg2b NCBI UniProt Show fit	secretogranin II (chromogranin C), b
chr19_-_28367413 Show fit	0.56	ENSDART00000079092	si:dkey-261i16.5 NCBI UniProt Show fit	si:dkey-261i16.5
chr13_+_28819768 Show fit	0.55	ENSDART00000191401 ENSDART00000188895 ENSDART00000101653	CU639469.1 NCBI UniProt Show fit
chr7_+_20535869 Show fit	0.54	ENSDART00000078181	zgc:158423 NCBI UniProt Show fit	zgc:158423
chr2_+_31833997 Show fit	0.54	ENSDART00000066788	epdr1 NCBI UniProt Show fit	ependymin related 1
chr4_+_3287819 Show fit	0.53	ENSDART00000168633	CABZ01085700.1 NCBI UniProt Show fit

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of foxl1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.4	GO:0006096	glycolytic process(GO:0006096)
0.0	1.1	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.8	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.2	0.5	GO:0061187	regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1	0.5	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.5	GO:0099550	trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.0	0.5	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.5	GO:1903670	regulation of sprouting angiogenesis(GO:1903670)
0.0	0.5	GO:0006885	regulation of pH(GO:0006885) regulation of cellular pH(GO:0030641)
0.1	0.4	GO:0042245	RNA repair(GO:0042245)

Showing 1 to 10 of 93 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.9	GO:0030141	secretory granule(GO:0030141)
0.0	0.8	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	0.7	GO:0031901	early endosome membrane(GO:0031901)
0.1	0.5	GO:0033181	plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0	0.5	GO:1902711	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1	0.4	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.4	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0	0.4	GO:0070822	Sin3-type complex(GO:0070822)
0.0	0.4	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	0.3	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)

Showing 1 to 10 of 27 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.2	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	1.1	GO:0015299	solute:proton antiporter activity(GO:0015299)
0.2	0.8	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.0	0.8	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.6	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.5	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.5	GO:0008503	benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0	0.5	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.5	GO:0030371	translation repressor activity(GO:0030371)
0.1	0.4	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)

Showing 1 to 10 of 68 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Total log-likelihood	Term	Description
0.6	PID AURORA B PATHWAY	Aurora B signaling
0.6	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.5	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.4	PID IL5 PATHWAY	IL5-mediated signaling events
0.3	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.3	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.3	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.3	PID AURORA A PATHWAY	Aurora A signaling
0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma

Showing 1 to 10 of 13 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.5	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.5	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.4	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.3	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.3	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling

Showing 1 to 10 of 14 entries

Results for foxl1

Z-value: 0.95

Motif logo

Transcription factors associated with foxl1

Activity-expression correlation:

Activity profile of foxl1 motif

Sorted Z-values of foxl1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of foxl1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: