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PRJNA207719: Tissue specific transcriptome profiling
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Results for foxk1_foxj3
Z-value: 0.49
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Transcription factors associated with foxk1_foxj3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| foxk1 | dr11_v1_chr3_-_40933415_40933415 | 0.70 | 1.9e-01 | Click! |
| foxj3 | dr11_v1_chr11_-_26362294_26362334 | 0.58 | 3.0e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of foxk1_foxj3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0003171 | atrioventricular valve development(GO:0003171) |
| 0.0 | 0.4 | GO:0097120 | receptor localization to synapse(GO:0097120) |
| 0.1 | 0.3 | GO:0033183 | negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915) |
| 0.1 | 0.2 | GO:0031630 | regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630) |
| 0.1 | 0.2 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.0 | 0.2 | GO:0055011 | atrial cardiac muscle cell differentiation(GO:0055011) |
| 0.0 | 0.2 | GO:0043328 | protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
| 0.0 | 0.2 | GO:0001964 | startle response(GO:0001964) |
| 0.0 | 0.1 | GO:0052576 | carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576) |
| 0.0 | 0.1 | GO:0048682 | axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 0.2 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.0 | 0.1 | GO:0098574 | cytoplasmic side of lysosomal membrane(GO:0098574) |
| 0.0 | 0.1 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.0 | 0.1 | GO:0032783 | ELL-EAF complex(GO:0032783) |
| 0.0 | 0.1 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.0 | 0.1 | GO:0017177 | glucosidase II complex(GO:0017177) |
| 0.0 | 0.1 | GO:0033557 | Slx1-Slx4 complex(GO:0033557) |
| 0.0 | 0.1 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.0 | 0.3 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
| 0.0 | 0.2 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.0 | 0.1 | GO:0004379 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) |
| 0.0 | 0.1 | GO:0004807 | triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929) |
| 0.0 | 0.1 | GO:0008184 | phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184) |
| 0.0 | 0.1 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.0 | 0.1 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.0 | 0.0 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.0 | 0.0 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.3 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.0 | 0.3 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.0 | 0.2 | REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS | Genes involved in TGF-beta receptor signaling activates SMADs |